History Main / JekyllAndHyde

* In ''Literature/PleaseDontTellMyParentsYouBelieveHer'' the retired supervillain First Horseman theorizes the main character, Penny, had a [[DownplayedTrope mild case]] of splitting into a [[AntiVillain mildly villainous]] personality called "Bad Penny" who a mind-reader confirms is almost the same as the Penny.

[[caption-width-right:350:[[MemeticMutation He can be your angle... or yuor devil.]]]]

* Kenshin and Battousai in ''Manga/RurouniKenshin.''

* ''Manga/{{Inuyasha}}'':
** Naraku and his evil human self, Onigumo.
** Suikotsu and his evil personality.

* ComicBook/TheSentry and The Void.

* ''Film/DrHeckylAndMrHype'': Parodied. This one differs in that the original "good" alter-ego is the ugly one.

* [[TokenGoodTeammate Glen]] and [[EvilTwin Glenda]] from ''Film/SeedOfChucky''.
* ''Film/AngelHeart'' (1987) with Creator/MickeyRourke.

** Done rather well with [[spoiler:Professor Yana]] and the Master.
** [[spoiler:The Doctor and the Dream Lord]]
** It happens again later in the episode "Nightmare in Silver" with [[spoiler:The Eleventh Doctor]]/Mr. Clever

* Scorpius's suicidal program inside Crichton's head in ''Series/{{Farscape}}''.

* Niki and Jessica from ''[[{{Series.Heroes}} Heroes]]''.

* Marcus Kane (Roadkill) and Needles Kane (Sweet Tooth) of the ''VideoGame/TwistedMetal'' series.
* Daniel and [[spoiler:Leo]] in ''VideoGame/{{Manhunt}} 2''.

* [[spoiler:Pat and his evil other-self Rey]] in the first ''VideoGame/MegaManStarForce''.

* ''WesternAnimation/{{Arthur}}'': "Jekyll, Jekyll, Hyde, Jekyll, Hyde, Hyde, Jekyll! "Jekyll, Jekyll, Hyde, Jekyll, HYDE!!!"
* ''WesternAnimation/AtomicBetty'': Minimus' two personalities. The book was even mentioned in the episode where he got stuck on "Hyde" mode.

* ''WesternAnimation/MyLittlePonyFriendshipIsMagic'': Princess Luna as Jekyll and Nightmare Moon as Hyde.

* This is how [[WebVideo/TheSpoonyExperiment Spoony]] and [[MadScientist Dr. Insano]] are portrayed in the Website/ThatGuyWithTheGlasses anniversary special ''WebVideo/{{Kickassia}}''. This is subject to NegativeContinuity;[[spoiler:''WebVideo/ToBoldlyFlee'' had retconned this into an anomaly caused by the PlotHole, in 'reality', Spoony and Insano are indeed two separate people.]]

[[caption-width-right:350:[[MemeticMutation He can be your angle or yuor devil.]]]]

* Chastity and Prixen, Martina and Sweater Puppy in ''Webcomic/TheMagnificentMilkmaid''.

* Tsubasa from ''[[Anime/MetalFightBeyblade Beyblade: Metal Masters]]'' has a dark side when he beyblade battles, making him obsessed with winning, going a bit mad. (He usually loses as a result)

* ''Radio/JohnFinnemoresSouvenirProgramme'': Series 1, Episode 3 includes a sketch consisting of Jekyll and Hyde writing letters to one another: Hyde is constantly sabotaging Jekyll's equipment, food, and moustache (and killing costermongers), and Jekyll is telling him off. Eventually, Jekyll teaches Hyde his place by threatening to subject him to a [[GroinAttack vasectomy]]. Hyde meekly apologizes to him and promises not to torment Jekyll again. [[AcceptableTargets He can still kill costermongers, though.]]

-->''You turn this? Into night,\\

* In ''TabletopGame/{{Pathfinder}}'', the Alchemist class can create a mutagenic potion that changes his/her personality and appearance, making the character more physically powerful at the expense of their mental abilities. The Master Chymist PrestigeClass takes this a step further, allowing the alchemist to create a unique infusion that, when taken, changes the character's personality and CharacterAlignment and possibly gives them a monstrous appearance; the two personas have separate minds and may work against each other. That said, the SplitPersonality doesn't have to be evil, just a different alignment; a LawfulGood chymist could have a ChaoticGood alter ego, for instance.

* "Jekyll and Hyde" by Music/FiveFingerDeathPunch is, unsurprisingly, about this trope.
-->''Oh, yo, yo, there's a demon inside!\\

* [=MazM=] made a [[VisualNovel/MazMJekyllAndHyde virtual comic]] adaptation of ''Literature/TheStrangeCaseOfDrJekyllAndMrHyde,'' which is pretty faithful save for Mr. Hyde being a little more bishounen than strictly necessary. And to be fair to the artist, he is never described as ugly in the book, just creepy and deep in the UncannyValley, and those aspects of his character come across just fine.

* "Jekyll and Hyde" by Music/FiveFingerDeathPunch is, unsurprisingly, about this trope. "Oh, yo, yo, there's a demon inside! Oh, yo, yo, just like Jekyll and Hyde!"

* "Jekyll and Hyde" by Music/FiveFingerDeathPunch is, unsurprisingly, about this trope. "Ohweeohweeoh, there's a demon inside! Ohweeohweeoh, just like Jekyll and Hyde!"

* Angel Starr from ''VisualNovel/PhoenixWrightAceAttorney'', complete with PeekABangs moving from one eye to another depending on whether she's sweet or sour.

* ''WesternAnimation/TheProudFamily'': In season 3, episode 10, it's revealed that Michael Collins has a monstrous Hyde persona that may have supernatural abilities.

* ''Film/Persona1966'': The dynamic between Elisabet and Sister Alma; the strange scenes in which one turns the other's head towards her; the reaction of Mr Vogler to Anna.

* ''Film/BeforeIHang'': After taking the age-reversal serum, Dr. Garth is occasionally overcome by a sudden urge to kill induced by the presence of an executed murderer's blood in his system. Garth does not remember committing these murders.

* In ''LightNovel/{{Kampfer}}'', Akane is a sweet, shy, bespectacled girl who often hangs out in the library. When she turns into a Kämpfer, then she becomes a real mean, foul-mouthed, trigger-happy bitch with a pair of pistols.

** Issue 173 of ''World's Finest Comics'' had a scientist named Dr. Aaron give Batman and Superman a potion that caused them to respectively transform into copies of their respective enemies Two-Face and Kralik (an obscure Silver Age Superman villain).

* In the ''VideoGame/{{Neptunia}}'' series, [=CPUs=] are a mild example. While there's only one consciousness and they retain all their memories, goals, etc. during the voluntary transformation, their normal and [[SuperMode Hard Disk Divinity]] forms can have very different personalities. [[TheSlacker Neptune's]] HDD form being a more mature LadyOfWar is one example. Another is Plutia, who goes from a friendly, scatterbrained girl to a [[FetishizedAbuser stone-cold]], [[TheDreaded ally-terrifying]] {{Dominatrix}}.