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* ''Animation/ThreeThousandWhysOfBlueCat'': In ''Dinosaur Times Series'' episode 118, a rock-paper-scissors fight between Blue Cat and Feifei ends with Feifei grabbing a big syringe labeled "Anesthetic" and using it to stun Blue Cat.

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* ''WesternAnimation/HazbinHotel'': In [[Recap/HazbinHotelS1E0ThatsEntertainment the pilot]]'s musical number "Inside of Every Demon is a Rainbow", a demon diagnosed with "evil" is prescribed "love + fun", which is injected from a syringe larger than their head.
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* ''VideoGame/MegaManXCommandMission'': One of [[WhiteMagicianGirl Cinnamon]]'s weapons is "Injector" - a pair of large syringes that completely replace both of her hands. For some reason it can inflict "[[DamageOverTime Virus]]" {{Status Effect|s}}, as in computer virus, since everyone involved are robots.
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* ''WesternAnimation/TheSuperMarioBrosSuperShow'' features an episode where King Koopa [[AttackOfThe50FootWhatever grows to a gigantic size]], and the gang use a huge needle to shrink him down. [[LampshadeHanging Lampshaded]] by Toad.
-->'''Toad:''' This is the second biggest hypodermic needle I've ever seen!\\
'''Luigi:''' What was the biggest?\\
'''Toad:''' My last flu shot![[note]]Which usually aren't that big![[/note]]
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* Suction syringes used to clear the airway in emergency medicine can look like this. They just don't have any needles.
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Giant medical syringes tend to occur alongside the NaughtyNurseOutfit in Japanese media as a form of [[VisualPun visual wordplay]]: "chu" means kiss, while "'''chu'''usha" means injection.

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Giant medical syringes tend to occur alongside the NaughtyNurseOutfit in Japanese media as a form of [[VisualPun visual wordplay]]: "chu" means kiss, while "'''chu'''usha" means injection.
injection. It often serves to exemplify the cuteness of the character holding it and any CuteAndPsycho tendencies she might have.
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[[folder:Fan Works]]
* ''Webcomic/NaruHinaChronicles'': In Chapter 9, Naruto tells a story to Hinata about how he was afraid of a needle that was as long as his arm during a medical exam.
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* In ''VisualNovel/Danganronpa2GoodbyeDespair'', [[BandageBabe Ultimate Nurse Mikan Tsumiki]] chases [[PlayerCharacter Hajime]] with one of these at the end of one of her Free Time events. [[spoiler:Her execution has Monokuma approaching her with a giant syringe of glowing green liquid... [[BaitAndSwitch which he then uses to fill a giant arm-shaped rocket up with fuel and launch Mikan into the stratosphere]].]]

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* In ''VisualNovel/Danganronpa2GoodbyeDespair'', [[BandageBabe Ultimate Nurse Mikan Tsumiki]] Tsumiki chases [[PlayerCharacter Hajime]] with one of these at the end of one of her Free Time events. [[spoiler:Her execution has Monokuma approaching her with a giant syringe of glowing green liquid... [[BaitAndSwitch which he then uses to fill a giant arm-shaped rocket up with fuel and launch Mikan into the stratosphere]].]]
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Want something to cause someone's [[AfraidOfNeedles trypanophobia]] to really act up? A needle so big, it's almost as big as the person using it! Never mind that such a huge needle would be very hard to target a vein with or how injecting an amount of serum over half of the human body's mass into the bloodstream probably isn't practical, because this is fiction. RuleOfCool and RuleOfFunny are king! Expect the needle to be so big that it requires ''at least'' two hands to carry, which carries a lot of impracticality on its own.

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Want something to cause someone's [[AfraidOfNeedles trypanophobia]] to really act up? A needle so big, it's almost as big as the person using it! Never mind that such a huge comically oversized needle would be very hard to target a vein with or how injecting an amount of serum over half of the human body's mass into the bloodstream probably isn't practical, because this is fiction. RuleOfCool and RuleOfFunny are king! Expect the needle to be so big that it requires ''at least'' two hands to carry, which carries a lot of impracticality on its own.



Such a huge syringe can probably make for an easy ImprovisedWeapon, if it's not just made as a weapon to begin with.

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Such a huge syringe can probably make for an easy ImprovisedWeapon, ImprovisedWeapon in the hands of a DeadlyDoctor, if it's not just made as a weapon to begin with.

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* ''Franchise/{{Digimon}}'': Demi-Devimon has an attack called Demi-Dart which has him hurling a (for him) over-sized syringe at an opponent. He tried to use it on TK in an effort take him forget about Patamon, so presumably it's filled with something less beneficial than medicine.

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* ''Franchise/{{Digimon}}'': ''Anime/DigimonAdventure'': Demi-Devimon has an attack called Demi-Dart which has him hurling a (for him) over-sized syringe at an opponent. He tried to use it on TK in an effort take him forget about Patamon, so presumably it's filled with something less beneficial than medicine.medicine.
* In the ''Anime/PokemonTheOriginalSeries'' episode "A Chansey Operation", when the [[TerribleTrio Team Rocket Trio]] try to steal all the injured Pokémon at a hospital James threatens Ash with one of these but is stopped by the titular Chansey.



* In ''VisualNovel/Danganronpa2GoodbyeDespair'', Mikan Tsumiki's execution has Monokuma approaching her with a giant syringe of glowing green liquid... [[BaitAndSwitch which he then uses to fill a giant arm-shaped rocket up with fuel and launch Mikan into the stratosphere]].

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* In ''VisualNovel/Danganronpa2GoodbyeDespair'', [[BandageBabe Ultimate Nurse Mikan Tsumiki's Tsumiki]] chases [[PlayerCharacter Hajime]] with one of these at the end of one of her Free Time events. [[spoiler:Her execution has Monokuma approaching her with a giant syringe of glowing green liquid... [[BaitAndSwitch which he then uses to fill a giant arm-shaped rocket up with fuel and launch Mikan into the stratosphere]].]]
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* Show up regularly in large animal veterinary medicine. It takes a ''big'' syringe to hold enough of most meds to treat half a ton of cranky horse/cow/whatever.

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* Show up regularly in large animal veterinary medicine. It takes a ''big'' syringe to hold enough of most meds medication to treat half a ton of cranky horse/cow/whatever.farm animal.
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* In ''WesternAnimation/MonstersVsAliens'' when the army arrives to deal with the [[AttackOfThe50FootWhatever newly giant]] Susan, they bring along a needle of sedative so large it needs to be administered via ballista. After getting hit in the leg, Susan pulls it out and throws it, impaling a soldier's foot.

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* In ''WesternAnimation/MonstersVsAliens'' when the army arrives to deal with the [[AttackOfThe50FootWhatever newly giant]] Susan, they bring along a needle of sedative so large it needs to be administered via ballista. After getting hit in the leg, Susan pulls it out and throws it, impaling a soldier's foot. This whole sequence is a ShoutOut to ''The Amazing Colossal Man'' as described below.
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* In ''Film/TheRescuersDownUnder'', Orville the albatross crashes and is brought to a hospital where the creepy nurse mice try to use a syringe that requires six of them to move across the room. Upon seeing it he breaks his restraints in panic and flies away.

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* In ''Film/TheRescuersDownUnder'', ''WesternAnimation/TheRescuersDownUnder'', Orville the albatross crashes and is brought to a hospital where the creepy nurse mice try to use a syringe that requires six of them to move across the room. Upon seeing it he breaks his restraints in panic and flies away.

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