These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Hilarious in Hindsight: Greg tells Jimmy to stop thinking about sex, to which Jimmy says "That's like Tiger Woods not thinking about sex." Now fast forward to 2010.
In one episode, Jimmy unintentionally tells Kevin Smith that his latest film (a WW2 comedy) sucks, at first Smith gets offended and demands an apology, but then he later admits to Jimmy that his film really does suck and he ends getting more funding to do a different film. A very similar scenario ended up happening with Smith in real life, after Smith directed Cop Out, Smith was pissed at critics for the negative reviews, then he lateradmitted the film really wasn't very good, and that was a big part of his decision to make Red State.
A movie Jimmy pitches to Savitsky (A sci-fi movie about clones used as organ donors) sounds a lot like The Island.
Squick: During the episode Speed Dating, Billy asks Jimmy to go on speed dating with him for moral support, a proposition that Christine refuses to approve of — that is, until Jimmy tells her that Billy spends many dateless nights fantasizing himself with her, a revelation that prompts Christine to change her mind at once.
Unfortunate Implications: In one episode, andropause is treated as essentially nothing but a joke. In fact, even after being given sympathy, Jimmy is viewed as less of a man because of it, by his own wife no less.
Double Standard: If his wife were referred to as "less of a woman" for going through menopause, then no one would be laughing.
The Woobie: Greg, certainly during his childhood years.