Reese, bar none, for being badass, funny, and surprisingly intelligent and competent. The fact she initially seems like a disposable Police Are Useless figure before ultimately saving the day helps a lot.
Of the college students, Sasha tends to be the most popular due to her sexy, fun, and sweet nature (a huge contrast to the overwhelming amount of asshole victims in the film).
Harsher in Hindsight: The reveal of Brenda as the killer became this after Rebecca Gayheart was convicted of vehicular manslaughter in 2001, especially given that said character's motivation involved her boyfriend being a victim of vehicular manslaughter.
Although Tosh was an obnoxious Jerkass, her death is genuinely upsetting as at one point she tries to call out Natalie's name only to have her mouth covered again, for all her many flaws she didn't deserve to die scared and with the only person who could save her unaware of her being murdered in front of her.
Sasha's death. Partly because she was one of the few actually likeable characters, partly because she sounds so terrified, even whimpering "I don't want to die" just moments before she does.
While Snopes existed at the time of the film's release, it's so widely used now that urban legends tend to have a much shorter shelf life, as a single person in a group of friends doing a Google search can stop a legend in its tracks. The classic decades-old legends are believed by approximately nobody nowadays.
The argument between Natalie and Tosh over the latter's internet use hogging the phone line. Anybody who grew up in the days of dial-up internet can attest to those sorts of arguments having been Truth in Television, but with broadband now the default, it dates the film firmly to the '90s.