These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Base Breaker: Is season two just as good as season one or is it a step down? The general consensus is that season two is weaker than season one due to the original creators and writers leaving, Paul Rugg and new writers coming in, and the show moving from Saturday morning to Tuesday afternoons (which, at the time, was a Friday Night Death Slot because weekday afternoon cartoons were starting to be phased out due to cable cartoons and the rise in talk shows and syndicated shows airing in the afternoon), making the show more like a horror version of Animaniacs, but, despite this, there are some funny moments
Retroactive Recognition: Two of Billy West's characters on the show (the toy store clerk on "Darla Doiley Demon Doll" and "Spawn of Santa" and the scientist in the B-movie parodies) sound like Professor Farnsworth (from the early episodes of Futurama when Farnsworth was dotty and lazy, but overall harmless and sane).
The voice Nancy Cartwright uses for Melissa Screetch is the one she now uses for Nelson Muntz on The Simpsons (deeper and scratchier rather than sounding like Kearney).
Seasonal Rot and They Changed It, Now It Sucks: The format went from a set format of three six or seven-minute shorts to several of irregular length in season two. Often instead of The Deadman family, Melissa Screech or Dr. Vic and company, the cartoon might star a minor character like Madame Olga or Becki-with-an-I. On top of this, the show became much more self-aware than before, owing it to the original creators leaving the series, and Paul Rigg of Animaniacs! fame stepping in.