- Fan-Preferred Couple: Many Science fiction fans like to, often jokingly, pair up Lt. Colonel Manning with a woman his size in the form of Nancy Archer.
- Memetic Mutation: "What sin could a man commit in a single lifetime..."
- Older Than They Think: In recent times, some have accused Glenn's accident of being a ripoff of the origin story of the Incredible Hulk — who in actual fact didn't make his debut until five years after The Amazing Colossal Man was released.
- The Other Darrin: Everyone was replaced in the sequel.
- Took the Bad Film Seriously: Whenever someone offers genuine praise for this film, it's typically regarding Glenn Langan's intense performance as the title character.
- Wangst: Glenn has an excuse, but it crosses the line into Narm frequently.
"What sin could a man commit in a single lifetime to bring this on himself?"