Broken Base: Anthony starting his own show while Opie and Jimmy stayed at Sirius first broke the fanbase between those loyal to Anthony, who refuse to support Sirius, and those who still wanted to support Jimmy. Once Opie was fired and Jimmy moved onto his own show with Sam Roberts, most of what is left of the fanbase now support Anthony and Jimmy's shows. Opie on the other hand...
Fandom Rivalry: With Howard Stern. Though it's more the rabid fans from each of these camps; while O&A and Howard have sparred a bit in the past, it pretty much ended once Anthony was fired in 2014.
Growing the Beard: The transition from WAAF in Boston to WNEW in New York, which is where the show came into its own.
The Scrappy: Opie. To some listeners, he played the Straight Man. However, it never helped that most of the time he either talked about his own career, stuck to talking about technical details, or had poor comedic timing, especially going up against Ant, Jim, and company. The acrimony towards him only grew since Ant's 2014 firing. In an interview with Joe Rogan shortly after Opie's 2017 firing, Jim Norton has said that him and Opie "simply stopped liking each other."