- Hilarious in Hindsight: The book came out over a decade before the Metal Gear series became popular. Reading it today, the inclusion of a genetically enhanced super ninja named "Hideo" is pretty funny.
- Les Yay: At first, Lady 3Jane appears to be giving Molly a Creepy Physical when she gets injured, but this comes across more like Intimate Healing than anything else.
- Seinfeld Is Unfunny: Every other cyberpunk work done after Neuromancer was released used it as a base, even by copying the terms at times. Combined with Science Marches On and the rise of the Internet, it can make some of the book's elements feel rather dated to the modern reader.
- This was even the case at the time; Gibson notes in one introduction that he was quite dejected when Blade Runner was released while he was still working on the book, as suddenly it would look like he was ripping off the film's aesthetics.
- Tear Jerker: when Corto-Armitage gets spaced, the usually relatively stoic Case starts crying. Admittedly, he's crying because he wants to keep his ability to stay in the Matrix, not because he liked Armitage, but still, it's kind of depressing seeing him that broken. It doesn't last long, though.