These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Anticlimax Boss: Wooly really isn't that tough at all if you did all your quests to get all the weapons and upgraded your jumping ability properly, as two of his attacks are easy to jump over and the third can be shot down by your slew of weapons.
Demonic Spiders: Zippers. They're fast and move erratically, making them harder to hit than the other enemies. And guess which Mook Wooly spawns in mass numbers periodically when you fight him?
Goddamned Bats: Repulsors. They fly very quickly and circle you attempting to touch you. Thankfully they don't have much health.