Trivia: The Brute Man
- Hey, It's That Guy!: Tom Neal, playing Clifford Scott, was the star of the Film Noir classic Detour (1945). He was also Bob Boxbody from Radar Secret Service.
- The wannabe hepcat little girl's mother is Aunt Flavia from The Thing That Couldn't Die.
- Missing Episode: The film was missing for about thirty years.
- Real Life Writes the Plot: Partially, Rondo Hatton suffered from acromegaly.
- Reality Subtext: The plot of the film was semi-biographical as the story revolved around a handsome college athlete scarred and turned into a monster by an accident. Hatton, who suffered from acromegaly, was dying during filming, and passed away shortly after filming. Universal felt guilty about exploiting Hatten's disease to the extent that they sold the film rights to Republic and completely disowned the film.