* AuthorExistenceFailure: ''Princess Mononoke'' was the last film Yoshifumi Kondo worked on as an animator before his death in 1998.
* CastingGag:
** Akihiro Miwa is a male who voices the female Moro in the Japanese version. He also had a career as a female impersonator.
** Gillian Anderson was famous for playing the TropeNamer and TropeCodifier of AgentScully. So who does she voice in the English dub? A wolf spirit.
* CelebrityVoiceActor:
** The English dub is ''made'' of this. Creator/BillyCrudup, Creator/ClaireDanes, Creator/GillianAnderson, Creator/MinnieDriver, Creator/BillyBobThornton, Creator/JadaPinkettSmith, and Creator/KeithDavid, among others.
** The original Japanese version is an interesting case: ''Princess Mononoke'' is the first Ghibli film that uses celebrities to provide the voice of the main characters of this film and all later Ghibli films. The only known professional with a named role in the movie is Creator/SumiShimamoto as Toki, Lady Eboshi's servant.
* CrossDressingVoices: Moro is voiced by a man in the Japanese version. This comes from Japanese mythology which says that wolves are always male-voiced (and cats always female-voiced), regardless of sex.
* ExecutiveMeddling: Thankfully averted, as opposed to earlier efforts to adapt Miyazaki's films into English. Miramax (read: the Weinstein brothers) wanted to cut 20 minutes from the English release, which was explicitly forbidden by the Disney/Ghibli distribution agreement. When Studio Ghibli producer Toshio Suzuki found this out after a very successful screening for the New York Film Critics Circle, he allegedly sent the Miramax executives a katana with a note attached: "No cuts."
* ExtremelyLengthyCreation: [[HayaoMiyazaki Miyazaki]] took 16 years to fully develop the characters and plot of the film.
* KeepCirculatingTheTapes: Disney's sale of Miramax was in the way of any possible re-release in America for several years. Miramax's rights lapsed at some point and Disney re-issued the film (officially re-printing the original DVD release from Buena Vista Home Entertainment re-badged in Disney's Ghibli package design) in 2012, with a Blu-ray release in 2014.
* LastOfItsKind: This is Studio Ghibli's final film to be drawn & colored on plastic cels, and is often thought to be the last cel-animated film in the world chronologically. After ''Mononoke'', Studio Ghibli switched to digital animation because cel animation had become too financially impractical.
* SoMyKidsCanWatch: Billy Bob Thornton explains on the DVD that this is part of the reason he took the part of Jigo. [[WhatDoYouMeanItsNotForKids Unfortunately...]]
* WhatCouldHaveBeen:
** The earliest concepts Miyazaki had that involved a Mononoke spirit was actually his re-telling of ''Beauty and the Beast''.
** Leonardo [=DiCaprio=] was considered to voice Ashitaka in the English dub. Possible CastingGag since Claire Danes was the voice of San, which would have made this the [[Film/WilliamShakespearesRomeoAndJuliet second time]] they had been StarCrossedLovers.
** Miyazaki intended for this film to be his last, but came out of retirement after conceiving the story for ''Anime/SpiritedAway''.