* CrossDressingVoices: Moro is voiced by a man in the Japanese version.
* ExecutiveMeddling: Thankfully averted, as opposed to earlier efforts to adapt Miyazaki's films into English. Miramax (read: the Weinstein brothers) wanted to cut 20 minutes from the English release, which was explicitly forbidden by the Disney/Ghibli distribution agreement. When Studio Ghibli producer Toshio Suzuki found this out after a very successful screening for the New York Film Critics Circle, he allegedly sent the Miramax executives a katana with a note attached: "No cuts."
* ExtremelyLengthyCreation: [[HayaoMiyazaki Miyazaki]] took 16 years to fully develop the characters and plot of the film.
* HeyItsThatVoice:
** The English dub is ''made'' of this. Billy Crudup, Claire Daines, Gillian Anderson, Minnie Driver, Billy Bob Thornton, Jada Pinkett Smith, and Keith David, among others.
** The original Japanese version is an interesting case: This is the first Ghibli movie that doesn't use professional voice actors for the main characters, relying entirely on [[CelebrityVoiceActor celebrities]] for them. The only known professional with a named role in the movie is Creator/SumiShimamoto as Toki, Lady Eboshi's servant.
** Moro's Japanese voice actor, Akihiro Miwa, would eventually go on to voice Arceus in ''Anime/PokemonArceusAndTheJewelOfLife''.
* KeepCirculatingTheTapes: Disney's sale of Miramax was in the way of any possible re-release in America for several years. Miramax' rights lapsed at some point and Disney re-issued the film (officially re-printing the original DVD release from Buena Vista Home Entertainment re-badged in Disney's Ghibli package design) in 2012.
* LastOfItsKind: This is Studio Ghibli's final film to be drawn & colored on plastic cels, and is often thought to be the last cel-animated film in the world chronologically. After ''Mononoke'', Studio Ghibli switched to digital animation because cel animation had become too financially impractical.
* SoMyKidsCanWatch: Billy Bob Thornton explains on the DVD that this is part of the reason he took the part of Jigo. [[WhatDoYouMeanItsNotForKids Unfortunately...]]
* WhatCouldHaveBeen: The earliest concepts Miyazaki had that involved a Mononoke spirit was actually his re-telling of Beauty and the Beast.