Trivia: Life With Louie
- Author Existence Failure: Mary Wickes, the voice actress for Louie's maternal grandmother, died during the series' production. "The Thank You Note" was subsequently produced in memory of her, wherein Louie's grandmother died as well.
- Hey, It's That Voice!: In addition to Louie Anderson, Jimmy Neutron voices Louie's friend/love interest Jeannie Harper and Kratos voices Andy's coworker Gus and neighbor Mr. Jensen. Michael Grunwald and the local bully Glen Glen are also voiced by, appropriately in the latter's case, Harold Berman.
- Keep Circulating the Tapes: Some sources claim the show is available on DVD in Poland. Other than that, good luck buying it!
- It is available in Poland indeed, but only the first two seasons, and without English audio.
- Germans Love David Hasselhoff: This show was ridiculously popular in Romania in the late 90's and early 00's, and still raises up a roaring nostalgia discussion whenever it's mentioned, partly due to being genuinely hilarious but mostly due to uncharacteristically good voice-over work by the dubbing studio. It's one of the few shows Romanians prefer to watch dubbed
- Talking to Himself: Louie Anderson voicing both his younger self and Andy.