Tear Jerker / Zombie Exodus

• In Chapter 3 of Part 5, you re-encounter Hadley, the cute little girl you met in Part IV. She's being chased by zombies, and if you so choose, you kill them and rescue her. After that you talk her for a bit and offer to take her back to the Cathedral, which she responds to with glee, since her entire family was slaughtered a few days ago. Just when you think everything will be fine, you find out that she was bit a by a zombie. Your choices are to leave her in the woods by herself, kill her when she's unsuspecting, or to stay with her until she dies. You can make a make-shift grave for her that badly scratches your hands, or if you're a priest you can say a prayer for her. And unlike other characters, you can't prevent her death.
• Uncle Lou's death at the hands of Tom. Made all the worse if you were dating him, because his jealousy and obsession with the Cathedral overcame his love for you, allowing him to sabotage the van, get Lou killed, and put you at risk.
• Emma's death. Good Lord, Emma's death. After everything the PC has done to protect their beloved little sister, they lose her to a zombie bite. Thank goodness this doesn't have to happen, depending on your choices.