Major spoilers abound.
- Atlantic Connection: Otto goes through the wringer in this chapter. First, his friend Gerhardnote disappears because the dangerous Sturmabteilung agents he didn't know were involved in their smuggling operation take poorly his and Father Lenz's decision to quit smuggling. His other friend Father Lenz is murdered by the Brownshirts as a warning of what will happen if he doesn't surrender the hotel to them. Then he discovers that the Brownshirts have hidden explosives in his hotel, one of which destroys his warehouse. And finally, Gerhard is revealed to have been his False Friend for all the years they've known each other as well as the Sturmabteilung member behind everything. Gerhard tries to shoot Anna, but Otto nearly dies by taking the bullet instead. He's granted a pardon for coming clean with his smuggling activities because of his role in exposing Gerhard's criminal ring, but he still misses Father Lenz.
- The Heir:
- Paola Tornetta has an utter breakdown due to her beloved Aldo being murdered. Having lost all her will to live, she jumps from the cliffs. When Anna and Luigi find her suicide note, the former blames herself for it, thinking that she should have realized how heartbroken the young lady was. In Exiled Dead, Anna is still blaming herself for it and brings flowers to Paola's grave.
- The story of Flora Molinelli. She married Albert Bernstein against her father's wishes and fled with him to South America. In response, her father disinherited her and forbade her mother and little brother Mario from contacting her ever again. Flora and Albert were so poor they had to survive without food even for days, and when this stressful lifestyle became too much for Albert, he left Flora to raise their son Osvald alone. Flora told Osvald bedtime stories about his rich grandfather's company and promised that he'll one day take over Molinelli Industries. Decades later, Osvald murders his cousin Aldo in order to inherit Molinelli Industries, only to end up being arrested, leaving the company to walk on thin ice and crushing Flora's dreams for her son.
- According to the game's social media accounts, Flora died when Osvald was six years old.
- Flora's little brother Mario doesn't end up having a much better life. He last saw his sister when he was a little boy and was told not to make contact with her by their father. Several months before The Heir, the old and ailing Mario ranted about Flora during one of his seizures, indicating that he has missed his big sister for all his life. His only child Aldo becomes murdered with no children of his own. The murderer turns out to be Osvald, the family's longtime employee and friend who has all along been Flora's embittered son, and he tricks his ailing uncle into signing a will that gives Osvald full ownership of Molinelli Industries. Exiled Dead reveals that after Mario learns of Aldo's death, he passes away. The wealthy family was destroyed in a story of love and vengeance.
- Unforgiven:
- The flashback revealing how exactly Roberto Fiore died. He was escorting his drunken best friend and brother-in-arms, Flavio Riva, from the cliffs. When Roberto questions why Flavio keeps acting erratically under the influence, Flavio rants that being second best to Roberto in everything ruined his life. Roberto is surprised that Flavio would say such things and even calls him his brother. This seems to knock some sense into Flavio, but when Roberto tries to take him home again, Flavio pushes him back in frustration, resulting in Roberto falling to his death. The flashback ends with Flavio regretting what he just did.
- For the rest of his life, Flavio is given a black rose by Roberto's mother who strongly believes that he killed her son out of jealousy and wants him to never forget that. The worst part is that Irene is Right for the Wrong Reasons, so these reminders of Flavio accidentally killing his best friend must have been real stabs in the heart for the broken war veteran.
- The revelation of Flavio's murderer. Rinaldo Fiore has harboured sadness and anger over Roberto's death as much as Irene, so after he learned what happened from Roberto's diary, he murdered Flavio for accidentally killing Roberto. He wished that by avenging their son, he'd win back his ex-wife who, consumed by her grief, left him to wallow alone in his own misery. When he tried wooing her earlier, her response was to angrily throw to the ground the flowers he was offering her. After he has confessed everything and called everyone out of thinking that he hasn't suffered from Roberto's death as much as Irene, he asks Officer Cozzi to imprison him, for he no longer has any reason to live in the society. The usually brusque Officer Cozzi softly tells him to follow him.Rinaldo: Miss Myers, you are very clever. But I don't regret it! All this time Irene was right. Our poor son died at the hands of his best friend… You all thought that it was just Irene who was angry about Roberto's death. [sheds tears] But he was my son too… "Irene is such a fragile person, she needs help" everybody used to say. But I missed him too.
Officer Cozzi: Calm down, Rinaldo.
Rinaldo: I have feelings! I still love Irene! And I still can't sleep at night when I think about our son Roberto. I did this for her, but I also did it for me… Giuseppe, put me in a cell. I don't have a place in a peaceful life anymore.
Officer Cozzi: Come this way, Rinaldo.
- The flashback revealing how exactly Roberto Fiore died. He was escorting his drunken best friend and brother-in-arms, Flavio Riva, from the cliffs. When Roberto questions why Flavio keeps acting erratically under the influence, Flavio rants that being second best to Roberto in everything ruined his life. Roberto is surprised that Flavio would say such things and even calls him his brother. This seems to knock some sense into Flavio, but when Roberto tries to take him home again, Flavio pushes him back in frustration, resulting in Roberto falling to his death. The flashback ends with Flavio regretting what he just did.
- The Only Redemption: Officer Cozzi's own wife turns out to be a fanatic who murdered their former housekeeper Cloe Como for having with him an affair that resulted in a baby. As Giuseppe asks from his wife if she's truly the murderer, she only replies with more Bible quotations in the midst of her Villainous Breakdown. The scene ends with him begging for her to stop. The scene then cuts to Anna departing from Porto Ceso on a train, with Luigi saying goodbye to her and giving her a bouquet. When he asks if they'll meet again, she says that she doesn't know, but is still glad that she met him. Her answer fits the fact that there aren't any more scheduled chapters for Chapter 2 announced, so it's really ambiguous if Anna visits Porto Ceso ever again.
- The Dada Killer:
- When the crime scene photo Anna takes without permission ends up in the newspaper (either because Sven finds it behind her back and uses it instead of the picture she took of the building exterior, or she has a change of heart and begs Sven to change photos, only for him to go back on his promise), the furious and disappointed Judit confronts her about betraying her trust and landing her in trouble with her superiors. The thoroughly ashamed Anna has to give her a rare car model and Amy the cat as apology gifts before Judit gives their friendship a second chance.
- Gustav Meisner is arrested as the prime suspect, much to the distraughtness of his mother Natalie whom Anna has to leave alone to cope. Though Judit is convinced Gustav is the Dada Killer, she admits that the hardest part of being a police is not catching criminals but watching innocent lives shatter. This becomes the last time Gustav and Anna see Natalie alive, for Natalie becomes the Dada Killer's next victim the following night.
- Ruben is found in a hotel room in an apparent act of unfaithfulness to Judit, and the body of Nadia Shwetz/Kiki Hag is discovered in the bathroom.note After Ruben is taken away, Judit is devastated by the apparent revelation that her fiancé was the Dada Killer all along. As Anna tries to console her, Judit thanks her for all her support and melancholically leaves the room. This becomes the last time we see her alive, for both she and Ruben are discovered murdered in his cell the next day, much to Anna's sorrow.
- The last cut scene where Judit is alive is the first time the heartbreaking soundtrack "Weeping Spire" plays out. It is heard again when Anna learns of Judit's fate. Three of her tears stain her diary page where she has written about this tragedy.
- Ladies of the Night:
- When Anna visits Gustav Meisner, it's made obvious how depressed his mother's murder has made him. Both he and the apartment he shared with Natalie have declined, and he has collected pictures of Oskar in hopes of finding the Dada Killer. Anna is concerned he'll endanger himself to avenge Natalie and can only hope she'll catch Oskar by herself while Gustav is still grasping at straws. She even writes in her diary that "of all the bodies I've ever laid eyes on, the most unsettling ones are the people who haven't died yet". What's more, one of the items you pick up as you help Gustav find his glasses is a photo of the mother and son.
- Though it's not much focused on, Anna and Ulli are still mourning Judit. When you sort through Judit's former office to find an example of Oskar's handwriting, you find a small photo of Ruben that has a heart painted on it with lipstick.
- It ultimately turns out that Susi Wiget is the twin who was murdered in Oskar's hideout when Petrus Krämer was captured and tied up there. When he woke up and searched the room, Mitzi burst in and begged her dead sister to wake up. As Petrus fled, the enraged Mitzi mistook him for the murderer, ran after him with a knife, and gave him the fatal stab wounds as her husband Johann Stumpf ran to the scene and tried to calm her down. As Ulli realizes that Johann has falsely confessed murdering Petrus to save his wife, he decides to let this charade continue, releases Mitzi and believes Johann may get five or less years in jail by pleading self-defense against the armed detective who'll likely be held accountable for Susi's murder.
- Grey Nature: When the opening cinematic narrates about poliomyelitis, an article of Eure Tages shows a photo of grieving parents who've lost their child to the disease.
- Forgotten Memento: Poor Ernestine. First she lost her colleague Dr. Kranz in The Dada Killer. Then she lost another friend Dr. Brüner in Gray Nature. Now she loses her husband Charles Kistner in this chapter. As she says, the people around her drop like flies.
- No Quarter: It's revealed that Manu used to live in a comfortable life with a proper house and toys until Leon gambled everything away, forcing Manu to endure being homeless and living on his own at a young age. Manu as a child being sad by himself during the opening cutscene especially is quite an upsetting sight to see.
