In this finale, Patrick Girts of Double Toasted guest stars as the talking...you know...of Lloyd's date/potential client!
- Honesty Is the Best Policy: After spending the entire episode looking for advice to tell Lloyd, Bonetti tells Chloe (as well as Lord directly) that it is best that he should just tell Penelope what he does; solves mysteries and meets new and interesting people all the time. Unfortunately, Penelope has already moved on from him and has a new, lucritive career via her singing vagina.
- Refusal of the Call: The episode ends with one of Professor Edward Mannix’s students asking Lloyd to help her find him the Amazon. He responds with a resounding “let him die.”
- Replacement Goldfish: Penelope for Lloyd post-breakup.Lloyd: If I'm gonna forget Glynis, I need to meet someone right away. Preferably someone who instantly reminds me of her. Maybe with a similar voice or something. That’ll make the transition easier.
- Running Gag: Whenever a character tempts fate hoping that there won't be any end-of-season cliffhangers, a Continuity Nod Sequel Hook to a previous episode manifesting in the form of either a Revenge plot or implications to a sequel plot.
- A man with a gun shows up at Sasquatch's burrito-stand to avenge the death of his porn-star/camper/sasquatch-hunter father Trevor.
- Lord Hobigee appears in Lloyd’s favorite bar to avenge the deaths of his sons Dookie and Zico.
- One of Professor Edward Mannix’s students begs Lloyd to go back into the Amazon to find him. You see? It’s different because its the exact opposite.
- Shout-Out: The premise and title are a reference to the 1977 talking-vagina comedy Chatterbox.
- Penelope’s vagina records a rendition of “The Michigan Rag.”
- Super Sex Organs: Penelope has a talking vagina. Oh yes, you heard me.
