Double Subverted: Alice is still very helpful in keeping Bob's life in order.
Parodied: Alice insists on helping Bob no matter how much he protests (quite accurately) that he's fine as is.
Zig Zagged: Sometimes Alice keeps an eye on Bob, other times she just accepts the inevitable.
Averted: Bob never comes close to suffering any consequences for his shenanigans.
Enforced: Bob is initially written as a loner, however executives decide it's too implausible that he could look after himself and Alice is written in.
Lampshaded: "Don't worry guys, Alice'll clean that up"
Exploited: Bob avoids appearing too sane because he's worried his friend Alice might move on if he can survive on his own.
Defied: Alice retreats to safety whenever Bob starts any of his Zany Schemes.
Discussed: "Ah, there's Alice and Bob. I've got no idea why she sticks by him, but I doubt he'd last long without her."
Conversed: "Are you one of those people who keeps their crazy friend in check?"
Deconstructed: Alice is essentially Bob's full time carer; he's completely dependent on her.
Reconstructed: Alice managed to teach him how to get by on his own long ago. They just hang around with each other because they're close friends as a result, Alice corrects Bob out of habit and Bob doesn't mind this for the same reason.
Played for Laughs: Alice is forever suffering in her efforts to prevent things getting too out of hand.
Played for Drama: Bob often comes close to getting them both killed and this puts a strain on their friendship.