- Duality Motif: Differently colored eyes foreshadow/reinforce a dual nature about the character.
- Electronic Eye: One eye is cybernetic.
- Glass Eye: One of their eyes is a prosthesis.
- Mad Eye: One of the eyes is considerably weirder.
- Magical Eye: One eye grants them magical powers.
- Mark of the Supernatural: Marks the character as special in some way, whether as magical, nonhuman, or something else entirely.
- Real Life: Heterochromia iridum Bear in mind that while healthy individuals can have this—see star baseball pitcher Max Scherzer—it is often a sign of medical problems.
- Red Right Hand: To foreshadow/reinforce something evil about the character.
- Shared Unusual Trait: Two or more characters have differently colored eyes because they're related or connected somehow.
When a character has differently colored eyes, it may represent one of the following: