John calls the Dunwych "tribals" but never refers to them as Natives or Native Americans. That's because they're the descendants of the same groups of Americans that survived the Rising. They're no more indigineous than John or the New Arkhamites.
Physics is utterly broken in the world of Post-Rising Earth with impossible things like the stars re-arranging and changing colors. Later, we find out that the world has been merged with the Dreamland. Of course everything is utterly upended. The universe as it used to be is completely changed!
Nyarlathotep's weird fascination with John makes a lot more sense once you realize he's the last of the Kastro'vaal. Nyarlathotep has been following this particular experiment for many millions of years.
Jackie is going to eventually be warped and twisted into a ghoul when she reaches maturity just like every other Half-Human Hybrid that exists in this world.
What does this mean for John's children, Gabriel and Anita?
