Due to the extensive list of the characters in Mad Men, the character sheet has been split between the main ensemble and the supporting cast. Beware of spoilers.
- The Main Characters note Don Draper, Peggy Olson, Joan Holloway, Pete Campbell, Roger Sterling, Bert Cooper, Lane Pryce, Harry Crane, Ken Cosgrove, Betty Draper, Sally Draper, Megan Draper
- Sterling Coopernote Paul Kinsey, Sal Romano, Duck Phillips, Freddy Rumsen, Allison, Lois Sadler, Kurt Smith and Smitty, John Hooker
- Sterling Cooper Draper Prycenote Stan Rizzo, Faye Miller, Michael Ginsberg, Dawn Chambers, Bob Benson, Lou Avery, Meredith, Caroline, Clara, Shirley, Scarlet, Johnny Mathis
- Cutler Gleason Chaoughnote Ted Chaough, Jim Cutler, Frank Gleason
- Families note Emile and Marie Calvet, Trudy Campbell, Cynthia Cosgrove, Anna Draper, Bobby and Gene Draper, Henry Francis, Pauline Francis, Margaret Sterling, Greg Harris, Gayle Holloway, Anita Olson, Katherine Olson, Jane Sterling, Mona Sterling, Abagail Whitman, Adam Whitman, Archie Whitman
- Other Charactersnote Carla, Bobbie Barrett, Jimmy Barrett, Ed Baxter, Glen Bishop, Manolo Colon, Midge Daniels, Lt. Don Draper, Suzanne Farrell, Lee Garner, Jr., Father John Gill, Francine Henson, Conrad Hilton, Jim Hobart, Stephanie Horton, Mack Johnson, Guy McKendrick, Rachel Menken, St. John Powell, Kitty Romano, Dr. Arnold Rosen, Sylvia Rosen