I'll be there (Saber Marionette J - Beware, video is spoiler-tastic, so close the window as soon as it loads in case you haven't seen all of the episodes)
Anata no Kokoro ni, the ending theme of Abenobashi Mahou Shoutengai. The yearning tone of Megumi Hayashibara's voice, the lyrics, and the black-and-white images of Osaka's past; if all that together doesn't call up a sense of loss, this troper can't imagine what will.