Castlevania (2017) does a lot this of this, somewhat out of necessity since many of the characters from the games didn't have much personality to begin with.
- Trevor Belmont while he was a bland hero when he debuted in Castlevania III: Dracula's Curse was later characterized in Castlevania: Curse of Darkness as a Hot-Blooded and proud warrior. In the show Trevor is a laid back alcoholic who leans towards being a Knight in Sour Armor who still very much enjoys fighting monsters and shows his gentle side to Sypha his lover, though he still remains very cynical as seen by the end of Season 3.
- Alucard is a textbook example of The Stoic in the games being quite emotionless in Castlevania: Symphony of the Night albeit with some explicit care for his teammates Trevor, Sypha and Grant and a strong love for his late mother Lisa. In the show Alucard is still hesitant to display too much emotion but is actually capable of being surprisingly immature, as seen with his rapport with Trevor. This includes giving Trevor the finger during their goodbye, something game Alucard would never do. Also in the games Alucard forms few attachments (as seen with Richter and Maria), while in the show Alucard deeply cares for his friends but couldn't express it, at least until they reunite in Season 4.
- Sypha Belnades, like Trevor, had little characterization beyond being a Blue Mage who was secretly a girl, though the manual and later games (such as Castlevania: Judgment) would make her to be a highly pious person who despises those tainted by the darkness and leans towards being a Knight Templar. In the show she's a compassionate person who shows no prejudice despite being ostracized herself as a Speaker.
- Dracula in the games (and most media for that matter) is a Evil Overlord with a few Affably Evil and Pet the Dog moments but is still full of malice for humanity. In the show Dracula is an Anti-Villain whose motivation (his wife being burned at stake by the church) is justified and sympathetic, also unlike the games Dracula notably spares innocent women, children and elderly when he can. In the games Dracula also had no qualms trying to kill his son Alucard while in the show Dracula holds back as not to truly hurt Alucard and eventually has a Heel Realization when he almost kills his son. The Stinger of Season 4 shows Dracula and Lisa Walking the Earth together after their resurrection and Dracula is even willingly to be a Retired Monster completely, something that he would never truly consider in the games.
- Carmilla, while The Vamp, was still unquestionably loyal to Dracula and would destroy anyone who defied him. In the show she thinks Dracula is a crazy old man and only acts like a faithful servant so she can stick the knife in at first opportunity, making her even more vile than her game counterpart. Carmilla is also a terrible misandrist in the show and by the later seasons so batshit insane, even her own allies are bothered by her tyranny. No tears are shed but her own when she explodes herself in an attempt to kill Isaac.
- Hector differs from Castlevania: Curse of Darkness, in the game he was a Defector from Decadence who goes on a Roaring Rampage of Revenge when his former ally Isaac kills his wife. In the show, Hector is more a morally ambiguous character. He burned his abusive family to death as a child and in the present he betrays his Benevolent Boss Dracula after being manipulated by Carmilla and suffers for it greatly. He becomes more heroic and closer to his game counterpart in Season 4, as he Grew a Spine and helps bring down Carmilla.
- Isaac also greatly differs from the Curse of Darkness where he was a Card-Carrying Villain with little to no redeeming traits whatsoever. In the show Isaac manages to be an Anti-Villain like Dracula whose actions are highly sympathetic and justified most of the time. Also in the game Isaac always hated Hector while in the show they were friendly with each other before Hectors's betrayal. By Season 4, Isaac has decided he wants to help make the world a better place, which is very far removed from the Smug Snake in the game.
- Saint Germain was a very enigmatic time traveler in Curse of Darkness who was quite the gentleman and gave mysterious warnings to Hector. In the show, while Germain is still mysterious, he's far more down to earth and occasionally crass and nor does he impose on the heroes' quest like the games, he doesn't even ask for help until Trevor and Sypha insist on helping him. Season 4 takes Germain on a different tangent as he makes a Deal with the Devil to cause the Apocalypse in order to see the woman he loved again, although he pulls a last minute Heel–Face Turn.
- Death is an Affably Evil Recurring Boss in the games who has Undying Loyalty to Dracula as his servant. In the show Death is a despicable and crass monster, pulling strings to usher in the Apocalypse using Dracula and his wife Lisa as a tool of ultimate destruction.
