History TearJerker / NoMatterHowILookAtItItsYouGuysFaultImNotPopular

* In chapter 46, the reveal that she [[spoiler: and Komiyama never started a good friendship in middle school.]] The very next chapter [[spoiler:effectively destroys any chances of the two becoming friends in high school in foreseeable future as well.]]
** [[spoiler:Said event also indicates just how far Tomoko's inability to understand other people goes and how easily she links everything to sex, to the point where it's clear that she is her own worst enemy at ever developing relationships with others.]]

* The scene where after she begins running to school in a positive mood, she ends up [[spoiler:vomiting in an alley.]] This scene is specially painful in the manga. This isn't helped by [[BystanderSyndrome bystanders not only ignoring her]], but also calling her a drunk.

* The [[spoiler: panties as tissue]] scene. It can be seen as funny, or as a teenage girl having a serious freakout.

* The moment when Kii-chan's [[BrokenPedestal pedestal was broken]].

* Creepy, wrong-assuming StalkerWithACrush that she is, you can't help but feel bad for Ucchi in chapter 131. Tomoko gave her a keychain just before they parted ways at Disneyland, and she seems to be the happiest she's ever been...[[YankTheDogsChain until she finds out the next day that Asuka got three]]. You can almost feel her heartbreak as she sees a vision of Tomoko drift off into the distance.

* The fact that these kinds of thing can happen in [[RealityEnsues real life]], where some people experience crippling amounts of social anxiety whether in the form of a learning or mental disability like Autism or Agoraphobia or whether the person is just naturally unable to make friends. Given that humans are social animals, social isolation can easily become a crippling and debilitating situation where a person can wither away from a combination of psychological issues stemming from their lack of social ability.

* Chapter 189 in general. Minami's HeelRealization has fully started to hit her by this point as she's being mercilessly picked on by Nori and Maki for hanging out with otakus which causes to inadvertantly lash out by making fun of Maki's boyfriend before realizing what she's done. Sachi, who's realized that Minami's pretty much drifted away from her for good, uses the opportunity to jump in and intentionally destroy the group while explaining that she's always hated Nori and Maki but was glad to have one last laugh with Minami (the one member of their friend group she actually liked) before leaving her and seeming to accept that their friendship is likely over. Minami can really do nothing but sit there in stunned, despondent silence before Yuu (who'd been studying nearby with Miho and Fuuka) comes over to ask if she's okay while Minami can only conclude that she'd never get it because she's probably a good person unlike her or her friends.

* In an omake that gives a WhatIf scenario where Tomoko becomes part of the popular group with Asuka. It's a BeCarefulWhatYouWishFor moment where Tomoko manage to get the popularity she was craving for before with lots of attention and multiple guys hitting on her in a daily basis. Ultimately Tomoko isn't happy at all since she doesn't actually enjoy being constantly asked out by random boys or not being herself at school, she only feels happy when doing her otaku interest at home which parallels Yuu's heavily implied issues in the canon.

** Asuka's scene, though brief, leaves a particularly strong impression. The first thing we see of her, she's sitting at a table holding a teacup, but looking spaced out and bored. Then, when Fuka asks her if Tomoko groped her, Asuka becomes oddly irritated, and tells Fuka to not ask about it so openly, despite Asuka herself offering Tomoko the opportunity in front of Fuka.

** And as the manga shows, it's really Tomoko's fault, as she grew obnoxious as she got older. And while she is quick to note her own shortcomings, this doesn't extend to realizing just how her behavior can annoy her brother.

** Worse, her behavior towards Tomoko after. She treats Tomoko like a pitiful little puppy and dresses her up, makes her wait somewhere in hopes of getting Tomok picked up. While she means well, it definitely goes from CringeComedy to sad how Kii-chan sees Tomoko as... a dog. Poor Tomoko.

* Tomoko crying herself to sleep because she's so "[[BlatantLies happy]]" is already sad enough, but her brother's complete and utter lack of empathy for her in the next room really drives it home. She's alone even in her own home.

* The StylisticSuck way that the ED song is sung; it sounds like Tomoko is on the verge of tears; a combination of desperation, heartbreak, and frustration. Further compounded by the last few lines of the song.

-->'''Tomoko''' All I see is my miserable self.

* Creepy, wrong-assuming StalkerWithACrush that she is, you can't help but feel bad for Ucchi in chapter 231. Tomoko gave her a keychain just before they parted ways at Disneyland, and she seems to be the happiest she's ever been...[[YankTheDogsChain until she finds out the next day that Asuka got three]]. You can almost feel her heartbreak as she sees a vision of Tomoko drift off into the distance.

* The scene where after she begins running to school in a positive mood, she ends up [[spoiler: vomiting in an alley.]] This scene is specially painful in the manga.

* The moment when Kii-chan's [[spoiler:[[BrokenPedestal pedestal was broken.]]]]

* The ending of chapter 27 (or episode 10 of the anime). Tomoko is shown starting a club of her own and bonding with her schoolmates... and then it's revealed that [[YankTheDogsChain it was all in her imagination]], her proposal for a club got rejected by the school council and she's sitting alone in her room, having tea with her plushies and retreating into her fantasies.