History Main / LongevityTreatment

* In ''Literature/{{Turnabout}}'' by Creator/MargaretPetersonHaddix, the government is working on a top-secret experiment in 2000 to reverse the aging process. And it works -- the main characters, who were extremely elderly and would have died before long, are given the chance to grow young again. Unfortunately, they haven't figured out a working way to ''stop'' the un-aging. Within a few years, the subjects start to notice a few memory-related side effects…

* The prolong treatments in the ''Literature/HonorHarrington'' books. Its most blatant example is Honor's mother, Allison, who at 90 is still very attractive and capable of bearing children. And since Honor received a more advanced version of the treatment, she's likely to live even longer. Also, people not only look very young for decades, they also have the hormonal levels corresponding with the apparent age ''for decades''. In the latter books, prolong becomes a key indicator of how socially and economically evolved a planet is: if you look old, it likely means you're poor. When the [[spoiler:Star Empire of Manticore]] is created, receiving prolong is made a fundamental, inalienable right of every citizen.

* In the ''Series/RedDwarf'' episode "[[Recap/RedDwarfSeasonXLemons Lemons]]", the guys find a Rejuvenation Shower that's supposed to turn old people young again and was common enough to be sold in [=IKEA=]. But the dwarfers end up putting it together wrong and it becomes a time machine.

* In the ''VideoGame/{{Fallout}}'' series, [[ILoveNuclearPower radiation]] under very specific conditions[[note]]by and large this seems to be long-term exposure to high levels of background radiation[[/note]] can render a person effectively immortal, turning them into a '[[OurGhoulsAreCreepier ghoul]]'. Ghouls [[TheAgeless do not age]] and even [[RadiationImmuneMutants heal from radiation]], but [[BodyHorror lose most of their skin and hair as it flakes off in big chunks]], suffer the long term effects of age leading to severe cataracts and arthritis, and become infertile. However, those exposed to too much radiation during ghoulification -- but not enough to outright kill them -- lose their mind and become 'feral', essentially mindless zombies. Ghouls who receive even more radiation can become Glowing Ones, ghouls that have a SicklyGreenGlow and can erupt in a burst of radiation to harm and heal. While most Glowing One ghouls are feral, one Jason [[MeaningfulName Bright]] is a Glowing One who hasn't become feral and leads a cult in a rocket facility in [[VideoGame/FalloutNewVegas Henderson]]. In ''VideoGame/Fallout4'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.

* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us," which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced {{nano|machines}}technology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain. The species from whose computer equipment carbosilicate amorphs has evolved already made themselves immortal and ran into several layers of problems. Still, there's a few remaining individuals alive and sane after their twelve million Terran years, [[http://www.schlockmercenary.com/2007-07-14 "give or take a little bit."]]

* ''VideoGame/TheSims 2'' features a carnivorous plant (the cowplant) that produces a substance that, when drunk, gives a Sim an extra day of life.
** ''VideoGame/TheSims3'' has a plant called '''life fruit''', which expand at least one day of a sim's life. Said fruit is a critical ingredient in the Ambrosia recipe that resets a Sim to the start of their current life stage.

* ''VideoGame/SentinelDescendantsInTime'' (based on Terry Dowling's short story "The Dormeuse and the Ichneumon") is set 1900 years in the future, where genetic treatments allowed mankind to live several times longer than a regular human. The main character Beni is 78 years old, but sounds like a 20-year-old man, which Dormeuse finds amusing when he enters her Tastan tomb. [[spoiler:It turns out that said tomb is meant to trap people, out of spite from the Tastans who couldn't achieve longevity because the treatments didn't affect them.]]
* In ''VideoGame/MoonChronicles'' an alien installation is discovered on the moon. Further investigation shows that the aliens have been [[HumanResources harvesting humans]] for centuries in order to make a substance that restores health and prolongs life.
* In the ''VideoGame/{{Fallout}}'' series, [[ILoveNuclearPower radiation]] under very specific conditions[[note]]by and large this seems to be long-term exposure to high levels of background radiation[[/note]] can render a person effectively immortal, turning them into a '[[OurGhoulsAreCreepier ghoul]]'. Ghouls [[TheAgeless do not age]] and even [[RadiationImmuneMutants heal from radiation]], but [[BodyHorror lose most of their skin and hair as it flakes off in big chunks]], suffer the long term effects of age leading to severe cataracts and arthritis, and become infertile. However, those exposed to too much radiation during ghoulification -- but not enough to outright kill them -- lose their mind and become 'feral', essentially mindless zombies. Ghouls who receive even more radiation can become Glowing Ones, ghouls that have a SicklyGreenGlow and can erupt in a burst of radiation to harm and heal. While most Glowing One ghouls are feral, one Jason [[MeaningfulName Bright]] is a Glowing One who hasn't become feral and leads a cult in a rocket facility in [[VideoGame/FalloutNewVegas Henderson]]. In ''VideoGame/Fallout4'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.
** The [[SuperSoldier Super Mutants]] altered by the Forced Evolution Virus in ''VideoGame/Fallout1'' are still around and at full fighting strength over a century later. Super Mutant bodies have increased healing, durability, and strength, but are infertile due to said healing[[note]]as Marcus says, it takes a few years to "get the juices flowing", so it doesn't mean they are castrated[[/note]] and lack secondary sexual characteristics. Of course, becoming a Super Mutant isn't easy, painless, or safe. It involves being dipped in a massive vat of FEV or having direct injections to force the change and only humans from Vaults have the minimum damage to their DNA to allow themselves to keep their intelligence afterwards before long-term Stealth Boy usage rots their minds. The East Coast Mutants in the [[VideoGame/Fallout3 Capital]] and [[VideoGame/Fallout4 Boston]] Wastelands are the result of leftover FEV found in Vault 87 in the former and used by the Institute in the latter.
** Another element of "feralization" in ghouls is socialization or general willpower/mental fortitude. Those that don't immediately go crazy may still decline over time if they're weak-willed or hide away in isolation and slowly go crazy.
* ''VideoGame/{{Stellaris}}'' has a variety of technologies that add extra years to your Leaders' life expectancies, it's also possible to use [[LegoGenetics gene tailoring]] to add the [[LongLived Enduring (+20 years) or Venerable (+80)]] traits to one or more of your species.
** There's also an event where [[ShoutOut you find a]] [[Film/TheFountain tree floating in space]] with sap that can extend your leaders' lifespans, or be distributed to the whole population for a boost in morale.
** It's also possible for certain leaders to become {{immortal|ity}} through events or other special conditions.

* Juraians and [[SpacePolice Galaxy Police]] officers get a treatment involving {{Nanomachines}} that gives them SuperStrength and lets them live for thousands of years.

* Rejuv in the ''Literature/AllianceUnion'' universe is made from a lifeform native to Cyteen and delays aging up to a century. Side effects include sterility and loss of hair color.

* In ''Literature/{{Turnabout}}'' by Creator/MargaretPetersonHaddix, the government is working on a top-secret experiment in 2000 to reverse the aging process. And it works -- the main characters, who were extremely elderly and would have died before long, are given the chance to grow young again. Unfortunately, they haven't figured out a working way to ''stop'' the un-aging.

In many science-fiction works, both CyberPunk and SpaceOpera, it's not uncommon for humans, or at least the upper classes, to [[LongLived live for centuries]]. Most often the reason for this is some form of technology ranging from alien substances to gene therapy to nanomachines.

[[folder: Comic Books ]]

* The Lazarus Pits used by ComicBook/RasAlGhul rejuvenate him every century or so. Various adaptations depict the process as having diminishing returns, putting more pressure on him to find a "worthy heir" before it stops working and / or he goes totally feral.

* ''ComicBook/JudgeDredd'': Aging has been slowed down quite a bit after most diseases have been eradicated and anti-aging drugs and skin grafting have become more advanced. Judge Dredd for instance is chronologically in his 70s, but still looks like a 40-something.
* One Wolverine story involves him helping out a caveman who was one of three abducted and experimented on by a [[{{Ultraterrestrials}} Deviant]] scientist attempting to discover a way to extend Deviant lifespans. The process worked, but he never gets to see it as he dies when their civilization is destroyed just after he finishes the procedure. That was thousands of years before recorded human history and the caveman is visibly aged but still perfectly well.
* The non-canon "The End" story for the ''ComicBook/FantasticFour'' takes place in a distant future where Reed Richards' genius has finally ushered in a utopia. One of his inventions was the "Methuselah Treatment" which has extended everyone's life expectancy into centuries.

[[folder: Film ]]

* In ''Film/InTime'', the aging gene has been "shut down", freezing aging at 25. But to prevent overpopulation and present an anvilicious message about income disparity, people are programmed to die at a certain time and use their remaining time as currency.
* In ''Film/JupiterAscending'', "Recode" rejuvenates people when they bathe in it. Kalique Abrasax is 14,004 years old and her mother was starting her 91st millenium when she was murdered. [[spoiler: And it's made from human cells, harvested a planet at a time.]]

* In ''Film/{{Tomorrowland}}'', Governor Nix looks exactly the same in 2015 as he did in 1964. Apparently thanks to some kind of shake he drinks every morning.

[[folder: Literature ]]

* The spice melange in ''Franchise/{{Dune}}'' can extend lifespans up to 300 years.

** The Bene Gesserit can also alter their own body chemistry to stop aging altogether if they choose to. They deliberately don't choose this because people would notice the resulting ageless women and conflict would result. That Alia has broken the taboo against it in ''Children of Dune'' is one of many things her mother Jessica takes issue with.
* The ''Literature/RedMarsTrilogy'' features a specialized gene therapy referred to as a "gerontological treatment". The books span over two hundred years and most the major characters, many of whom were ''already'' in their 40s and 50s at the start of the series, are alive and active that entire time due to repeated use of the treatment. However, the treatment cannot overcome TheFogOfAges. [[spoiler: In the final book, a separate treatment is created for this, giving them nigh-eidetic memory. The increasing age of the characters leads to many dying of old age in their [=200s=] despite the gerontological treatments]]
* In Creator/RobertAHeinlein's future history series, particularly ''Literature/MethuselahsChildren'' and ''Literature/TimeEnoughForLove'', humanity develops a form of rejuvenation through blood replacement after a group of naturally long-lived people reveal themselves and then hijack a starship when the rest of the species demand they reveal their "secret". Later more advanced methods including complete body replacement are developed.
* In the ''Literature/TakeshiKovacs'' series, people are implanted with "cortical stacks" at birth that record one's brain state so that when they die, they can be "resleeved" in a new body.

* In Creator/JohnScalzi's ''Literature/OldMansWar'', rejuvenation treatment via consciousness transfer to a genetically enhanced body is only available to military personnel--and the minimum age for joining the military is 75.

* Citizens of Literature/TheCulture are genetically engineered to live for centuries, longer if they feel like it.
* In John Norman's ''Literature/{{Gor}}'' novels, the Caste of Physicians developed a treatment called the Stabilization Serums, which allowed the recipient to live for hundreds of years.[[note]]In 'Marauders of Gor', Tarl meets someone who is almost certainly the legendary founder of Torvaldsland, which would make him about 1000 years old.[[/note]] The Priest-Kings, the PhysicalGods of the setting, have a similar treatment, the oldest being about 5,000,000 years old.

* Poulsen treatments in the ''{{Literature/Hyperion}}'' series. It will extend one's life to a few centuries - one person lived close to a thousand, although it also included a lot of time as a HumanPopsicle. However, after a few times, the skin starts literally glowing blue, and it is of limited use on old people. [[ArtificialHuman Androids]] are built with the process being constant in their bodies, and can live for six or more centuries without visible signs of aging.
* The same name was later used in Creator/RobertReed's novel, ''Literature/TheRemarkables''. It can greatly expand one's life (beyond the already genetically enhanced ~150 year lifespan), though the treatment leaves visible marks - one of the characters who has had extensive treatments has an almost young face, but wrinkled hands and oddly colored skin.
* In the ''Literature/ChildrenOfSteel'' series it's mentioned that humans can take life extension treatments that make the age of some of the executives hard to discern. There's no indication whether it's possible to use those on animorphs.
* In Creator/MikhailAkhmanov and Christopher Nicholas Gilmore's ''Literature/CaptainFrenchOrTheQuestForParadise'', the Cellular Regeneration treatment available on most worlds has, effectively, turned humanity into TheAgeless. People choose when to "freeze" their age with most picking sometime in their 20s, although some wait until 30 in order to look "more mature". The only people who die of old age are either criminals on worlds where capital crime is punished by aging (reversing the treatment) and on recently-settled worlds where CR machines have not yet been set up. It's mentioned by the titular protagonist that, even before CR, various treatments (including cloned organs and blood vessel cleansing) have extended expected lifespans to centuries.

** The Jacksonians have a highly unethical treatment in which the brain of a wealthy client is transferred into the body of a younger clone. Mark Vorkosigan has made it his life's work to eliminate that practice, and as of the chronologically latest book was about to begin testing of a treatment that could potentially revert someone from 'old' to 'middle aged'.

* The setting of ''Literature/ThePrincesOfTheAir'' has a longevity treatment which is only available to the rich and powerful. When we first meet the protagonist he's running a con where the bait is illicit access to the longevity treatment.

* Dystopian setting for ''Literature/TheDeclaration'' by Gemma Malley has the "Longevity" treatment, which starts at 16 years old when the user signs the titular Declaration in exchange for a regular supply of pills and renuncing to ever have children (to avoid surpopulation). Not only the second volume reveals it needs [[PoweredByAForsakenChild foetuses cells]], the formula is ''incomplete'', as shown in the third volume when people go senile and suddenly die because their treatment doesn't work anymore.

* In ''Series/TheTwilightZone1959'' episode "The Trade-Ins", an elderly couple go to a clinic that can give them new, younger bodies. But, they only have enough money for one of them.

** The sarcophagus can extend the life of a human without a [[PuppeteerParasite Goa'uld]] for 700 years or so, and a human that is a host to Goa'uld for millennia. Unfortunately it makes the user megalomaniacal. [[ImmortalityImmorality Because reasons.]]

** In the episode ''2010'' the Aschen give earth a life-extension drug that serves to explain why SG-1 hadn't aged at all in ten years. It also turned out to cause sterility, as part of an Aschen plot to depopulate earth so they could turn it into an agricultural colony. Necessitating TimeTravel to prevent the earth-Aschen alliance.

* ''Series/StarTrekDeepSpaceNine''. Parodied in "In The Cards". Dr. Giger believes that people die because their cells get bored of doing the same thing day in and day out, literally boring them to death. His invention intends to provide stimulating entertainment to the user's cells to entice them into immortality. After listening to this spiel, the protagonists decide that--even given the miraculous science of the ''Star Trek'' universe--this guy's a loon.

[[folder: Tabletop Games ]]

* In ''TabletopGame/ArsMagica'', Hermetic Magi are able to create a longevity ritual that can drastically slow the aging process. The ''Mysteries'' sourcebook provides a significantly more powerful version in the form of an alchemical Elixir of Life.

* A couple of nanosymbionts in ''GURPS TabletopGame/TranshumanSpace'' extend life expectancy by 10 years and expensive "rejuvenation" treatments can actually reverse the aging process.
* The space marines' biological enhancements in ''TabletopGame/{{Warhammer 40000}}'' setting allow them to live a millennium or more. Unenhanced human nobles and dignitaries have "rejuvenat" or simply "juveant" treatments, enabling them to live several centuries longer than ordinary humans. Some sources imply that certain variants of these procedures use raw materials [[PoweredByAForsakenChild From Living Children.]]

* In ''TabletopGame/HcSvntDracones'' the Mega Corps don't want immortal customers, even though they have the technology for it. Pulse and Progenitus do offer "graceful aging" treatments that keep a client healthy and active through their nineties, but include a "termination date" somewhere around age 100. Still, some very valuable employees manage to secure long-term contracts that include body replacement at the end of their natural lifespan.

[[folder: Video Games ]]

* In the ''Franchise/MassEffect'' series, humans commonly live to 150 or so due to gene therapies and drugs. This puts us in the mid-range for lifespans in that universe.

** There is a secret project called 'The Longevity Vaccine' and another called 'Clinical Immortality'. The former is a simple injection, the latter involves removing the [[BrainInAJar brain, spine, and eyes and placing them in a glass machine]] giving the user [[ExactWords Clinical Immortality]].
** It is mentioned that the player character goes through some sort of gene therapy on a regular basis to explain how he stays alive for the full five centuries of the game.

* In ''VideoGame/SwordOfTheStars II'' anagathics technologies extend the lifespans of your admirals.
* ''VideoGame/SentinelDescendantsInTime'' (based on Terry Dowling's short story "The Dormeuse and the Ichneumon") is set 1900 years in the future, where genetic treatments allowed mankind to live several times longer than a regular human. The main character Beni is 78 years old, but sounds like a 20-year-old man, which Dormeuse finds amusing when he enters her Tastan tomb. [[spoiler: It turns out that said tomb is meant to trap people, out of spite from the Tastans who couldn't achieve longevity because the treatments didn't affect them.]]
* In ''VideoGame/MoonChronicles'' an alien installation is discovered on the moon. Further investigation shows that the aliens have been harvesting humans for centuries in order to make a substance that restores health and prolongs life.
* In the ''Videogame/{{Fallout}}'' series, radiation under very specific conditions [[note]](by and large seems to be long-term exposure to high levels of background radiation)[[/note]] can render a person effectively immortal, turning them into a 'ghoul.' Ghouls do not age and even heal from radiation, but lose most of their skin and hair as it flakes off in big chunks, suffer the long term effects of age leading to severe cataracts and arthritis, and becoming infertile. However, those exposed to too much radiation during ghoulification - but not enough to outright kill them - lose their mind and become 'feral', essentially mindless zombies. Ghouls who receive even more radiation can become Glowing Ones, ghouls that have a SicklyGreenGlow and can erupt in a burst of radiation to harm and heal. While most Glowing One ghouls are feral, one Jason [[MeaningfulName Bright]] is a Glowing One who hasn't become feral and leads a cult in a rocket facility in [[VideoGame/FalloutNewVegas Henderson]]. In ''Videogame/{{Fallout 4}}'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.
** While the Super Mutants altered by the Forced Evolution Virus in ''VideoGame/{{Fallout 1}}'' are still around and at full fighting strength over a century later. Super Mutant bodies have increased healing, durability, and strength but are infertile due to said healing [[note]](as Marcus says, it takes a few years to "get the juices flowing", so it doesn't mean they are castrated[[/note]] and lack secondary sexual characteristics. Of course, becoming a Super Mutant isn't easy, painless, or safe. It involves being dipped in a massive vat of FEV or having direct injections to force the change and only humans from Vaults have the minimum damage to their DNA to allow themselves to keep their intelligence afterwards before long-term Stealth Boy usage rots their minds. The East Coast Mutants in the [[Videogame/Fallout3 Capital]] and [[Videogame/Fallout4 Boston]] Wastelands are the result of leftover FEV found in Vault 87 in the former and used by the Institute in the latter.

** It's also possible for certain leaders to become [[{{Immortality}} immortal]] through events or other special conditions.

[[folder: Webcomics ]]

* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us," which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain. The species from whose computer equipment carbosilicate amorphs has evolved already made themselves immortal and ran into several layers of problems. Still, there's a few remaining individuals alive and sane after their twelve million Terran years, [[http://www.schlockmercenary.com/2007-07-14 "give or take a little bit."]]

* In ''Webcomic/QuantumVibe'', rejuvenation treatments are even more readily available. One of the main characters is reportedly in his third century, but there's evidence that he's ''[[ReallySevenHundredYearsOld over 500 years old.]]''
* ''Webcomic/TheDragonDoctors'': The effects of a FountainOfYouth were reverse-engineered about a century earlier. The Fountain itself is a deadly lake that regresses everything to nothing within its radius, but learning its magic has allowed other characters to get regular rejuvenation treatments. In Mori's backstory it is shown that she helped discover it and was rather old before someone tried to kill her by dunking her head in the lake, she went from about 60 to 20, she also adopted the sole survivor of the previous team to the area who had been regressed to a baby.
* In ''Webcomic/GenocideMan'' the titular Genocide Men had a variety of procedures done that allowed them to continue operating well into their 90s or 100s, Jacob Doe is 98. Artificial glands to stabilize hormones, nanotube-laced skeletons to prevent broken bones, and telomerase to prevent cancer. The former two sets of augmentations have [[SuperSoldier other bonuses]] as well.

[[folder: Web Original ]]

* In ''WebOriginal/OrionsArm'' most [[HumanSubspecies nearbaselines]] are genetically engineered to live about 500 years. But due to medical nanotechnology and brain uploading most in the Sephirotic Empires live to 3,000 before succumbing to ennui or [[AscendToAHigherPlaneOfExistence transcending]].

[[folder:Web Serial Novel]]

* One of the very rare dungeon lot drops in ''Literature/TheDailyGrind'' can add months to your total lifespan.

[[folder: Western Animation ]]

* In ''WesternAnimation/BatmanTheAnimatedSeries'' Poison Ivy under the guise of Dr. Demeter offers this treatment to rich industrialists but in reality is turning them into trees as karmic justice for their environmental destruction. She has no qualms about going after their friends or loved ones as well.
* In ''WesternAnimation/{{Gargoyles}}'', the Illuminati provides life extending drugs to its senior members such as Mace Malone, who is in remarkably good health for a man in his nineties. When Matt Bluestone remarks on this, Mace wrly responds that [[SignedUpForTheDental Matt should see their dental plan]], flashing a smile full of perfect white, even, natural teeth.

[[folder: Real Life ]]

* While life extension systems which would prolong your life by decades do not exist (yet), certain measures can be taken to prolong your life at best, or avert major maladies ''at least'' with proper hygiene, nutrition, regular exercise and barring any serious illness or injury, you can expect to live to a ripe old age.

[[/folder]]

[[folder: Live Action TV ]]

* In ''Turnabout'' by Creator/MargaretPetersonHaddix, the government is working on a top-secret experiment in 2000 to reverse the aging process. And it works -- the main characters, who were extremely elderly and would have died before long, are given the chance to grow young again. Unfortunately, they haven't figured out a working way to ''stop'' the un-aging.

* The same name was later used in Creator/RobertReed's novel, ''The Remarkables''. It can greatly expand one's life (beyond the already genetically enhanced ~150 year lifespan), though the treatment leaves visible marks - one of the characters who has had extensive treatments has an almost young face, but wrinkled hands and oddly colored skin.

* In ''Film/{{Tomorrowland}}'' Governor Nix looks exactly the same in 2015 as he did in 1964. Apparently thanks to some kind of shake he drinks every morning.
* In ''Film/JupiterAscending'' "Recode" rejuvenates people when they bathe in it. Kalique Abrasax is 14,004 years old and her mother was starting her 91st millenium when she was murdered. [[spoiler: And it's made from human cells, harvested a planet at a time.]]

* One Wolverine story involves him helping out a caveman who was one of three abducted and experimented on by a [[{{Ultraterrestrials}} Deviant]] scientist attempting to discover a way to extend Deviant lifespans. The process worked, but he never gets to see it as he dies when their civilization is destroyed just after he finishes the procedure. That was thousands of years before recorded human history and the caveman is still perfectly well.

** It's also possible for certain leaders to become {{Immortal}} through events or other special conditions.

* Dystopian setting for ''The Declaration'' by Gemma Malley has the "Longevity" treatment, which starts at 16 years old when the user signs the titular Declaration in exchange for a regular supply of pills and renuncing to ever have children (to avoid surpopulation). Not only the second volume reveals it needs [[PoweredByAForsakenChild foetuses cells]], the formula is ''incomplete'', as shown in the third volume when people go senile and suddenly die because their treatment doesn't work anymore.

* One Wolverine story involves him helping out a caveman who was one of three abducted and experimented on by a [[{{Ultra terrestrial}} Deviant]] scientist attempting to discover a way to extend Deviant lifespans. The process worked, but he never gets to see it as he dies when their civilization is destroyed just after he finishes the procedure. That was thousands of years before recorded human history and the caveman is still perfectly well.

* In ''WesternAnimation/BatmanTheAnimatedSeries'' Poison Ivy under the guise of Dr. Demeter offers this treatment to rich industrialists but in reality is turning them into trees as karmic justice for their enviromental destruction. She has no qualms about going after their friends or loved ones as well.

* Anagathic drugs in ''TabletopGame/{{Traveller}}'', frequently banned or controlled. Require monthly doses or the character is forced to make an aging roll.

** There's also an event where [[ShoutOut you find a]] [Film/TheFountain tree floating in space]] with sap that can extend your leaders' lifespans, or be distributed to the whole population for a boost in morale.