History Main / BloodyMurder

* Vanica from ''Manga/BlackClover'' uses her Blood Magic to attack by solidifying it, forming wings and a giant claw from which she can unleash bladed beams of blood.

* ComicBook/{{Superman}} was once bitten by Franchise/{{Dracula}}, but his solar-powered blood made the vampire lord ''explode''.

* In ''Anime/DarkerThanBlack'', the contractor Wei Zhi Jun is shown to have ''[[PortalCut teleporting]]'' blood, which he uses offensively by cutting himself and splattering it on his opponents before he it activates it by snapping his fingers to take chunks of people and objects with it.

* [[Franchise/TheDCU DC's]] ''Franchise/{{Lobo}}'' has the ability to spawn a full-sized clone from a single drop of blood, though it was genetically removed by Vril Dox, his former employer in ''ComicBook/LEGIONDCComics''. Different writers have seen fit to bring it back at their discretion.

* Vlad King aka Sekjiro Kan in ''Manga/MyHeroAcademia'' has the quirk “blood comtrol”. He can manipulate his own blood after ejecting it from his glove. He once pinned a Dabi clone to the wall with it and ended the fight in three seconds. He can reabsorb the blood after the fight.

* Surprisingly uncommon in ''VideoGame/{{Bloodborne}}'', considering how prominent blood is in the game, but it does pop up a couple of times. Queen Yharnam uses her blood as a weapon in her fight, either by spraying toxic blood or by fashioning blades out of it. In the Old Hunters DLC, Maria also powers up her swordplay with blood magic in her battle, which she learned from the Cainhursts. The player can get in on the action with the Chikage, a Cainhurst weapon that's halfway between a cavalry sabre and a katana. Its trick weapon mode involves magically coating its blade in your blood, draining your health over time but slightly boosting your attack range and massively boosting your damage.

** Both types of vampire can use various different attacks with blood. The Stone Mask vampires can freeze blood on contact and [[EyeBeams fire high-pressure streams of blood out of their eyes]]. The [[OurVampiresAreDifferent Pillar Man]] Esidisi can heat his blood to 500 degrees Celsius(932 degrees Fahrenheit) and shoot it out of his veins.
** Josuke's [[FightingSpirit Stand]], Crazy Diamond, [[HealingHands can restore objects to a previous state]], which Josuke once [[LethalHarmlessPowers exploits]] after spilling some of his own blood on his opponent. When he put some more blood from the same wound on a shard of glass, "restoring" the two pieces causes the shard to [[HomingProjectile home in on his target]].
** Part 5's Risotto Nero, who can manipulate iron, including the iron in blood. This ended in such lovely images as Risotto forming a pair of scissors in his enemy's throat, and forcing him to ''vomit up razor blades.''

* In ''WebOriginal/{{Mortasheen}}'', the [[http://www.bogleech.com/mortasheen/viviphage.htm Viviphage]] has the power to control blood, ripping out the blood of its victims. It also happens to be the ultimate form of the [[OurVampiresAreDifferent Vampire race]] and look like a bacteriophage. There's also the [[http://www.bogleech.com/mortasheen/mothneaser.htm Mothneaser]], one of the game's OlympusMons that produces massive quantities of blood that it doesn't just turn into weapons or horrible "blood golems" but also can insert tendrils of its own blood into people to puppeteer their bodies.

* Outenkun of ''Manga/SoulHunter'' and his blood that melts metal and can turns into noxious, acidic gas.

[[caption-width-right:304:Just had to eat at Denny's, didn't you?]]

* ''VideoGame/MortalKombat9'' DLC character, Skarlet, uses her own blood as a weapon and is, herself, a creature made of blood. Noob Saibot in the same game bleeds a black inky substance that he also uses to create the clones that he uses in his attacks.

* In ''VideoGame/DeathStranding'', the many [[OurGhostsAreDifferent Beached Things]] that stand in your way react very poorly to Sam's body due to his status as a "repatriate" ([[ResurrectiveImmortality someone who's able to resurrect from death]]), so throughout many points in the game, Sam stock ups on forming anti-BT weapons [[AbnormalAmmo coated with his bodily fluids]], from shower water, urine, feces, and most prominently, his blood. This sometimes works as a handy way to stabilize difficulty following a rough encounter as it means Sam can come better equipped, but this also means that sometimes, [[CastFromHitPoints the player will have no choice but to sacrifice some blood voluntarily]] to deal with something expected to be really big.

* Surprisingly uncommon in ''VideoGame/{{Bloodborne}}'', considering how prominent blood is in the game, but it does pop up a couple of times. Queen Yharnam uses her blood as a weapon in her fight, either by spraying toxic blood or by fashioning blades out of it. In the Old Hunters DLC, Maria also powers up her swordplay with blood magic in her battle, which she learned from the Cainhursts.

** Emishi also has flammable blood, and once used it to [[spoiler:try to burn Shido to death]]. It's a desperate, last-chance attack, though; he usually sticks to his [[WhipItGood whip]].

* ''LightNovel/FateRequiem'': Erice Utsumi can turn her blood into bullets and weapons like axes. Her blood is also toxic to Servants and when she kills them with it, the blood absorbs and dissolves their spirits.

* Mirai from ''LightNovel/BeyondTheBoundary'' has "cursed blood"; as well as being highly corrosive, she can form it into a sword with which to attack. However, [[BlessedWithSuck due to these powers]], she is treated as "cursed" and ostracized by her fellow youmu hunters; there's also the risk of her losing too much blood and passing out.

* ''Manga/InuYasha'' can use his own blood as an EmergencyWeapon, throwing crescent-shaped, sharp-edged splatters that are similar in effect to RazorWind. Though it's rarely used after he learns a SwordBeam attack.

* In ''LightNovel/SwordArtOnline'', during ''Alicization Uniting, when Eugeo's Blue Rose Sword snaps in half, he uses Incarnation to reforge the blade using how own blood so that Kirito can use it. The new sword is red in color and is christened the Red Rose Sword.

* One guy in ''LightNovel/TrinityBlood'' has blood that instantly combusts when it comes it contact with air. The main character can also make a scythe out of his while in his SuperMode.

* ''Franchise/TheFlash'': After experimenting on his blood with the blood of metapowered criminals, the hemophilic Ramsay Rosso developed the ability to transform his flesh into a blood-like physiology and became the supervillain Bloodwork.

* ComicBook/TheJoker has highly toxic blood; DependingOnTheWriter, it's either from [[NoOSHACompliance his tumble into a vat of chemicals]] [[MonsterClown that resulted in his appearance]], or from [[GettingHighOnTheirOwnSupply sampling his own toxins]].
* [[Franchise/TheDCU DC's]] ''ComicBook/{{Lobo}}'' has the ability to spawn a full-sized clone from a single drop of blood, though it was genetically removed by Vril Dox, his former employer in ''ComicBook/{{LEGION|DCComics}}'' Different writers have seen fit to bring it back at their discretion.
* The [[Franchise/GreenLantern Red Lanterns]] have this as their main gimmick. To go a little more in depth, should you feel great rage and receive a Red Ring, you ''vomit out all your blood,'' which is then replaced by red light constructs of your bloodstream. Which means that any Red Lantern who overcomes the UnstoppableRage the ring induces (with one exception) dies immediately.

* Franchise/{{Superman}} was once bitten by Franchise/{{Dracula}}, but his solar-powered blood made the vampire lord ''explode''.

* ''Literature/GrimoiresSigil'': Harper's specialty is in blood magic, which she uses to easily dispatch the Kesterline mages holding her hostage due to Sebastian choosing to leave her alone, but can also be used to heal by using it to clot wounds.
* Sanguine from ''Literature/SuperMinion'' has control over blood. He can bleed himself for a weapon to attack with, and can also bleed an enemy dry from the slightest wound.
* Naofumi has a spell in ''LightNovel/TheRisingOfTheShieldHero'' granted to him by [[EvilWeapon the Rage Shield]], "Blood Sacrifice". [[CastFromHitPoints By expelling enough of his own blood,]] it summons a terrible maw to appear and bite down on his victim before dragging their bloodied corpse into a pool of bubbling blood.
* Granny Weatherwax from the ''Literature/{{Discworld}}'' novel ''Literature/CarpeJugulum''. [[spoiler:There's really not more to it than that: she uses blood as a weapon, and the weapon is her. Well, the blood is a delivery system...]]

* In the ''Series/DoctorWho'' novel ''Forever Autumn'', the Doctor temporarily disrupts the antagonists' biological ship by smearing a drop of his blood over one of its surfaces. Later on [[spoiler:he threatens to overwhelm the ship completely by slitting his wrists all over the floor]].

* Creator/JohnScalzi's ''Literature/OldMansWar'':

* ''TabletopGame/Warhammer40000'':

* Werewolf blood is toxic to vampires in ''Series/{{Being Human|UK}}''. George exploits this in one episode by biting his own wrist and forcefeeding his blood to a vampire, killing it.

** Mayuri tends to fill Nemu's body full of poisons and various experimental drugs. In at least once case, when an enemy tried to use her body to regenerate himself, the poison was transferred to him with dire results.