History GameBreaker / TheBindingOfIsaac

* Most people will tell you that Blood Rights is a terrible item due to being fueled by your health. Combine it with Taurus however and once per room you can spam it incessantly for the duration of your invulnerability. Guaranteed to utterly tear apart all but the most resilient bosses, but even then they will only be hanging by a thread after this treatment.

* The Stop Watch. All enemies (and their bullets) get the slowdown effect. ''Forever''. You have to pump 999 coins into the shop donation machine over many playthroughs to unlock it, but once unlocked it becomes part of the shop item rotation. The slowdown isn't just a time effect, either. Enemy bullets have a duration, so their range is drastically reduced. Enemy charge attacks likewise wear out almost instantly, giving them no charge distance. The only thing you have to watch out for is some enemy familiars (the Ovum of Blighted Over, the Mask of Mask and Heart if the Heart is alive), as they aren't affected by the slowdown. Tracking bullets may also chase you down unexpectedly.
** The Stop Watch is such a game breaker that it has gained a small {{hatedom}} among the ''Isaac'' community for making runs ''too easy'', being avoided as if it were a {{Scrappy Mechanic}} or even hacked out of the game altogether.

* The Stop Watch. All enemies (and their bullets) get the slowdown effect. ''Forever''. You have to pump 999 coins into the shop donation machine over many playthroughs to unlock it, but once unlocked it becomes part of the shop item rotation. The slowdown isn't just a time effect, either. Enemy bullets have a duration, so their range is drastically reduced. Enemy charge attacks likewise wear out almost instantly, giving them no charge distance. The only thing you have to watch out for is some enemy familiars (the Ovum of Blighted Over, the Mask of Mask and Heart if the Heart is alive), as they aren't affected by the slowdown. Tracking bullets may also chase you down unexpectedly. The Stop Watch is such a game breaker that it has gained a small {{hatedom}} among the ''Isaac'' community for making runs ''too easy'', being avoided as if it were a {{Scrappy Mechanic}} or even hacked out of the game altogether.

* Stop Watch. All enemies (and their bullets) get the slowdown effect. ''Forever''. You have to pump 999 coins into the shop donation machine over many playthroughs to unlock it, but once unlocked it becomes part of the shop item rotation. The slowdown isn't just a time effect, either. Enemy bullets have a duration, so their range is drastically reduced. Enemy charge attacks likewise wear out almost instantly, giving them no charge distance. The only thing you have to watch out for is some enemy familiars (the Ovum of Blighted Over, the Mask of Mask and Heart if the Heart is alive), as they aren't affected by the slowdown. Tracking bullets may also chase you down unexpectedly.

* Using A Card Against Humanity in a 2x2 room while holding the Petrified Poop. A Card Against Humanity fills the entire room with poop, while the Petrified Poop drastically increases the pickup drop rate from poops, and both items are relatively easy to obtain. Depending on how much of the room is clear, this can net a lot of coins/bombs/keys early in the game.

* Using A Card Against Humanity in a 2x2 room while holding the Petrified Poop. A Card Against Humanity fills entire room with poop, while the Petrified Poop is drastically increasing pickup drop rate from poops, and both items are relatively easy to obtain, which makes this combination one of the easiest ways to max out your coins/bombs/keys early in the game.

** One of the new items shown off is [[https://www.youtube.com/watch?v=IW4CiNmfgL4 Monstro's Lung]]. By itself, it doesn't seem to be that bad, considering it just allows you to shoot multiple blood tears in one charged shot. And then you get the [[StuffBlowingUp IPECAC]]. A combination of this with being able to fire multiple shots at once pretty much guarantees a OneHitKill on most enemies. And then you get an unknown item (most likely Cricket's Body) that ''increases the amount of explosions''. And then you get another unknown item (most likely Fire Mind) that '''''[[NoKillLikeOverkill leaves behind a wall of fire for each explosion]]'''''.

** One of the new items shown off is [[https://www.youtube.com/watch?v=IW4CiNmfgL4 Monstro's Lung]]. By itself, it doesn't seem to be that bad, considering it just allows you to shoot multiple blood tears in one charged shot. And then you get the [[StuffBlowingUp IPECAC]]. A combination of this with being able to fire multiple shots at once pretty much guarantees a OneHitKill on most enemies. And then you get an unknown item (most likely Cricket's Body) that ''increases the amount of explosions''. And then you get another unknown item (most likely Fire Mind) (revealed to be that '''''[[NoKillLikeOverkill leaves behind a wall of fire for each explosion]]'''''.

** One of the new items shown off is [[https://www.youtube.com/watch?v=IW4CiNmfgL4 Monstro's Lung]]. By itself, it doesn't seem to be that bad, considering it just allows you to shoot multiple blood tears in one charged shot. And then you get the [[StuffBlowingUp IPECAC]]. A combination of this with being able to fire multiple shots at once pretty much guarantees a OneHitKill on most enemies. And then you get an unknown item that ''increases the amount of explosions''. And then you get another unknown item that '''''[[NoKillLikeOverkill leaves behind a wall of fire for each explosion]]'''''.

* Speaking of Tammy's Head, Rebirth has made it absolutely absurd when stacked with Tear effects. Brimstone? Produces an 8-way laser of death (that stacks with Homing Tears effect). Parasite? Produces more sub-teardrops, and once again, stacks with Rubber Cement to make bouncing, splitting tears. And yes, you can make them be homing, piercing, bouncing, splitting tears. All that, and Tammy's Head recharges once per room.

* The "Magic Fingers" item allows you to do room-wide damage by spending a single coin, essentially a Blood Rights only with money instead of life. It gets gamebreaking because the damage it does scales with Isaac's damage, which can make it absurdly powerful if you get high damage/low rate of fire items. As long as you have enough money to pay for it, which is easy enough to come by, you can stroll through most of the game with the press of the button. Even if you have to penny pinch, it can at least let you get through the bosses with ease.

* The "Magic Fingers" item which it destroys the enemies in a room with just one coin. Even bosses are not safe from it (even bosses like Satan and Mom.

* Stop Watch. All enemies (and their bullets) get the slowdown effect. ''Forever''. You have to pump 999 coins into the shop donation machine over many playthroughs to unlock it, but once unlocked it becomes part of the shop item rotation.

** Unlocking the Soul also unlocks The Mind, which is permanent mapping (including secret rooms!) in just one item.

* And then there's the [[AnimalCrossing Gnawed Leaf]]. It makes Isaac immune to all damage when he stands still for two seconds, but that immunity goes away when he moves or shoots a tear. If you couple this with an item that does damage by itself without any player input, it makes it impossible to lose under most circumstances. Especially if you have a level 3 or 4 Meat Boy or Bandage Girl. Then, as long as no enemy is behind an obstacle, you just sit back and let Meat Boy or Bandage Girl kill everything. Even with just a damaging orbital it can trivialize a lot of rooms.

*** Blank Card + Rune of Jera + a single battery consumable = Infinite item duplication.

* The Soul is one of the most difficult unlocks in the game, requiring winning with a OneHitPointWonder through the path without a real EleventhHourSuperpower to assist you. What does it do? BulletDodgesYou in a game where many of the final bosses employ BulletHell. It also helps that you unlock The Mind in the process, which is permanent full mapping in a single item.

* Tammy's Head and Brimstone now have synergy, turning a single tear burst into an infinite range eight-direction blast that can kill everything in many rooms in one shot. It has a recharge time of one room. Also, there's now a character who ''starts'' with Brimstone, and while Azazel's Tammy burst does have a limited range it's still extremely powerful.

* Speaking of Tammy's Head, Rebirth has made it absolutely absurd when stacked with Tear effects. Brimstone? Produces an 8-way laser of death (that stacks with Homing Tears effect). Parasite? Produces more sub-teardrops, and once again, stacks with Rubber Cement to make bouncing, splitting tears. And yes, you can make them be homing, piercing, bouncing, splitting tears. All that, and Tammy's head recharges once per room.

* Stop Watch. All enemies (and their bullets) get the slowdown effect. ''Forever''. It takes a while to unlock, but when you do you can buy it in shops.

* Two words: [[http://platinumgod.co.uk/dark-bum Dark Bum]]. He converts every two hearts he picks up into a soul heart, though he may occasionally toss out a spider (hostile or friendly), instead. Considering that there are a ton of Red Heart drops throughout the game, this makes getting a full set of soul hearts trivially easy for anyone remotely good at dodging. He's especially good when used by Eve (whose CriticalStatusBuff isn't negated by Soul Hearts) and [[spoiler:???/Blue Baby]], neither of whom have much use for red hearts otherwise. He used to be even more broken, dropping hearts at a 1:1 ratio with no downside.

* Two words: [[http://platinumgod.co.uk/dark-bum Dark Bum]]. He converts every two hearts he picks up into a soul heart, though he may occasionally toss out a hostile spider, instead. Considering that there are a ton of Red Heart drops throughout the game, this makes getting a full set of soul hearts trivially easy for anyone remotely good at dodging. He's especially good when used by Eve (whose CriticalStatusBuff isn't negated by Soul Hearts) and [[spoiler:???/Blue Baby]], neither of whom have much use for red hearts otherwise. He used to be even more broken, dropping hearts at a 1:1 ratio with no downside (and even ''more'' broken with characters who can't or shouldn't use red hearts, like Eve, Azazel or [[spoiler: ???/Blue Baby]]).

* Two words: [[http://platinumgod.co.uk/dark-bum Dark Bum]]. He converts every two hearts he picks up into a soul heart, though he may occasionally toss out a spider, instead. Considering that there are a ton of Red Heart drops throughout the game, this makes getting a full set of soul hearts trivially easy for anyone remotely good at dodging. He's especially good when used by Eve (whose CriticalStatusBuff isn't negated by Soul Hearts) and [[spoiler:???/Blue Baby]], neither of whom have much use for red hearts otherwise. He used to be even more broken, dropping hearts at a 1:1 ratio with no downside.

Note that any game breaker may be balanced simply being hard to find/get. Due to the random nature of the game there may not be a single one listed during a run, but also due to the difficulty the game has it may be required to have at least one of the game breakers to simply get through. Put simply: despite the number of game breakers you may not find one, or they may be balanced during the later levels of the game.

** Additionally, if you use a fully charged item, the 3 charges per room limit ''resets''. This means entering a room with 3 charges, waiting to use the item and waiting ''again'' with an enemy still present will yield a total of six bars per room, no 9-volt required. Find a room with an easy enemy (like a single doppelganger in the womb or utero) and your supply of bombs can be entirely converted to a supply of blue hearts by combining the battery with a nail or book of revelations. With Ipecac, fetus in a jar or epic fetus, you can create as many blue hearts as you have the patience to generate!

* Technology 2 (which shoots a laser that is [[DeathOfAThousandCuts weak as all hell but hits constantly]]). Because it hits very quickly, it will almost always activate items with on-hit properties such as Mom's Contact (which gives your shots a chance to freeze enemies), The Mulligan (which gives you a chance to spawn a kamikaze attack fly whenever you shoot an enemy) or the Common Cold (Which gives shots a chance to poison).
** It's even more overpowered with Polythemus, which does ridiculous damage but sets tears to minimum. It's balanced, but with Technology 2 will down all bosses in seconds and one shot enemies.

* Finding the Bloody Penny allows one to convert money drops into red hearts. Blood donation machines do the reverse, but can pay out nickels or dimes. In tandem, this can produce infinite money and consumable health for a floor. If found in an arcade, the combo can be exploited for infinite keys, bombs and Skatole. Even if the blood donation machine happens pay out, it will droop the Blood Bag, which fills heart containers and gives an HP up, or the IV Bag, which acts as a portable, more reliable blood donation machine.
** Especially if you consider that the Blood Bag's cooldown is slightly shorter than the MercyInvincibility. Which means that, with a single half-heart (on the first 6 floors), you can use it twice and get 3-4 coins on average, which in turn give you 1-2 hearts on average. So, even without a slot machine, you can get infinite coins and hearts.
* Dollar (max cash) + Money Is Power [[ExactlyWhatItSaysOnTheTin (boosts damage proportional to money total)]]= Total Annhilation.

* Combining Mom's Knife + Mom's Eye + Loki's Horns + Triple Shot + My Reflection + Tiny Planet could accurately be described as a "death blender", because this item combination ''(that Edmund McMillan says is so rare, you should probably go out and buy a lottery ticket after tearing through everything in your path)'' flings out three knives in each of the four cardinal directions (for a total of ''twelve knives'') that quickly spin around you before returning. [[http://bindingofisaac.com/post/82762252439/thats-not-a-knife It has to be seen to be believed.]]