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** Post-Crisis ComicBook/{{Supergirl}} has [[NuclearNasty Reactron]]. Over the course of both her solo series, and the ''NewKrypton'' crossover, the two clashed repeatedly, leading to Reactron's murder of Supergirl's father, her mother Alura's ColdBloodedTorture of Reactron upon his capture, and the eventual destruction of New Krypton when Reactron blew up himself, the planet, and Kara's mother. For both of them the conflict was always personal.
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** Post-Crisis ComicBook/{{Supergirl}} has [[NuclearNasty Reactron]]. Over the course of both her solo series, and the ''NewKrypton'' ''ComicBook/NewKrypton'' crossover, the two clashed repeatedly, leading to Reactron's murder of Supergirl's father, her mother Alura's ColdBloodedTorture of Reactron upon his capture, and the eventual destruction of New Krypton when Reactron blew up himself, the planet, and Kara's mother. For both of them the conflict was always personal.
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* [[ComicBook/TheMightyThor Thor]] has ComicBook/{{Loki}}.
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* [[ComicBook/TheMightyThor Thor]] has ComicBook/{{Loki}}.SelfDemonstrating/{{Loki}}.
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** TheKingpin (who would also be an impressive fourth place on Spidey's Arch Enemy list, as well as a contender for ThePunisher's). As the ultimate gang boss, everything that Daredevil fights against can be traced back to him, and he's orchestrated several collapses of Matt's life, during "Born Again", "Devil In Cell Block D" and various other arcs, hurting him worse than anyone else ever has. As practically the {{deuteragonist}} of the series, Kingpin will always be a part of Matt Murdock's life for better or worse, a fact that his late wife Vanessa, comments on in-series.
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** TheKingpin ComicBook/TheKingpin (who would also be an impressive fourth place on Spidey's Arch Enemy list, as well as a contender for ThePunisher's). As the ultimate gang boss, everything that Daredevil fights against can be traced back to him, and he's orchestrated several collapses of Matt's life, during "Born Again", "Devil In Cell Block D" and various other arcs, hurting him worse than anyone else ever has. As practically the {{deuteragonist}} of the series, Kingpin will always be a part of Matt Murdock's life for better or worse, a fact that his late wife Vanessa, comments on in-series.
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** [[AntagonisticOffspring Later, Logan's son]] {{Daken}}.
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** [[AntagonisticOffspring Later, Logan's son]] {{Daken}}.{{ComicBook/Daken}}.
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** Hugo Strange was likely intended to be the Moriarty to Batman's Holmes, until The Joker usurped him in popularity. His initial plots involved rather fantastic devices such as towering monster men and "fear dust". [[http://i6.photobucket.com/albums/y241/Hefmeister/hugo7crop-1.jpg He also served as an inspiration for The Joker]], who appeared two months after his debut. Hugo Strange did not appear for 37 years after his intended death in ''Detective Comics'' #46, but since then, his appearances have generally involved exploiting Batman's secret identity and ruining Bruce Wayne so that he alone can be Batman.
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* ComicStrip/SuskeEnWiske: Krimson is the main recurring villain.
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* ComicStrip/SuskeEnWiske: ComicBook/SuskeEnWiske: Krimson is the main recurring villain.
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* ComicStrip/{{Jommeke}}: Jommeke and his friends are often confronted by Anatool, the servant nobody can trust. However, he is somewhat of a HarmlessVillain, seeing that Jommeke and his friends can easily thwart his evil schemes. De Koningin van Onderland ("The Queen of Onderland") on the other hand doesn't appear that much in Jommeke's stories, but when she does she is generally considered to be his most frightening and dangerous opponent.
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* ComicStrip/{{Jommeke}}: ComicBook/{{Jommeke}}: Jommeke and his friends are often confronted by Anatool, the servant nobody can trust. However, he is somewhat of a HarmlessVillain, seeing that Jommeke and his friends can easily thwart his evil schemes. De Koningin van Onderland ("The Queen of Onderland") on the other hand doesn't appear that much in Jommeke's stories, but when she does she is generally considered to be his most frightening and dangerous opponent.
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* ComicStrip/{{Asterix}}: Julius Caesar would be this, even though there's a mutual respect between the Gauls and Caesar and they usually leave each other alone. Caesar is often seen as a VoiceOfReason and above the corruption of many of his legionnairies. He will defend the Gauls if he understands that some Romans have done them wrong in a way that even he couldn't defend.
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* ComicStrip/{{Asterix}}: ComicBook/{{Asterix}}: Julius Caesar would be this, even though there's a mutual respect between the Gauls and Caesar and they usually leave each other alone. Caesar is often seen as a VoiceOfReason and above the corruption of many of his legionnairies. He will defend the Gauls if he understands that some Romans have done them wrong in a way that even he couldn't defend.
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* ComicStrip/BuckDanny: Lady X.
* ComicStrip/LuckyLuke: Lucky Luke often faces off against the Daltons.
* ComicStrip/LuckyLuke: Lucky Luke often faces off against the Daltons.
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* ComicStrip/BuckDanny: ComicBook/BuckDanny: Lady X.
*ComicStrip/LuckyLuke: ComicBook/LuckyLuke: Lucky Luke often faces off against the Daltons.
*
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* ComicStrip/TheSmurfs: Gargamel who, in the comics at least, wants to turn the Smurfs into gold. In the animated series he simply wants to eat them.
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* ComicStrip/TheSmurfs: ComicBook/TheSmurfs: Gargamel who, in the comics at least, wants to turn the Smurfs into gold. In the animated series he simply wants to eat them.
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* ComicStrip/DonaldDuck: Scrooge McDuck often combats the Beagle Boys. His business rival Flintheart Glimgold sometimes funcions as his own personal arch enemy too. However his most dangerous opponent is Magica Despell, who threatens to steal his lucky dime and melt it into the Vesuvius volcano.
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* ComicStrip/DonaldDuck: ComicBook/DisneyDucksComicUniverse: Scrooge McDuck [=McDuck=] often combats the Beagle Boys. His business rival Flintheart Glimgold sometimes funcions as his own personal arch enemy too. However his most dangerous opponent is Magica Despell, who threatens to steal his lucky dime and melt it into the Vesuvius volcano.
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* ComicStrip/{{Tintin}}: Tintin's arch nemesis is Rastapopoulos.
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* ComicStrip/{{Tintin}}: Franchise/{{Tintin}}: Tintin's arch nemesis is Rastapopoulos.
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* ComicStrip/BlakeAndMortimer: Blake and Mortimer often face off against Olrik.
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* ComicStrip/BlakeAndMortimer: ComicBook/BlakeAndMortimer: Blake and Mortimer often face off against Olrik.
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* ComicBook/SwampThing has Anton Arcane, his most persistent enemy, who at least deserves credit for [[JokerImmunity simply not staying dead.]]
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** General Zod is the Arch Enemy of Superman's father Jor-El, the one responsible for stopping his coup and imprisoning him in the Phantom Zone, with Superman inheriting the grudge. Following Superman's defeat of Zod in ''Last Son'' and the events of ''ComicBook/NewKrypton'', the rivalry turns very personal for the both of them.
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** General Zod is the Arch Enemy of Superman's father Jor-El, the one responsible for stopping his coup and imprisoning him in the Phantom Zone, with Superman inheriting the grudge. Following Superman's defeat of Zod in ''Last Son'' and the events of ''ComicBook/NewKrypton'', the rivalry turns very personal for the both of them.them, and along with Luthor and Brainiac, he's one of the few beings that Superman genuinely hates.
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for the hundredth time—Darkseid is a general DCU villain, not a Superman one. Not to mention that Darkseid is \'\'not\'\' \"the one villain bad enough to push Superman into a homicidal rage\". Brainiac and Mongul I have both evoked that reaction.
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* Franchise/{{Superman}} has ComicBook/LexLuthor, {{Brainiac}}, General Zod, and {{Darkseid}}.
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* Franchise/{{Superman}} has ComicBook/LexLuthor, {{Brainiac}}, and General Zod, and {{Darkseid}}.Zod.
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** While he could be seen as the BigBad of the whole DC Universe, {{Darkseid}} definitely could fit this role for Superman, as he's the one villain bad enough to push Supes into a homicidal rage.
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** {{X-23}} and Kimura.
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** {{X-23}} ComicBook/{{X 23}} and Kimura.
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*** In addition to Spidey, Venom has Carnage, his son, as an arch-enemy. Spider-Man can't normally defeat Carnage on his own. The fact that Venom willingly comes to aid Spider-Man shows that he must hate Carnage more. Either that, or he just wants to be the one to deliver the killing blow.
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*** In addition to Spidey, Venom has Carnage, ComicBook/{{Carnage}}, his son, as an arch-enemy. Spider-Man can't normally defeat Carnage on his own. The fact that Venom willingly comes to aid Spider-Man shows that he must hate Carnage more. Either that, or he just wants to be the one to deliver the killing blow.
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* ComicStrip/PaulusDeBoskabouter: Paulus the wood gnome has one recuring arch nemesis and that is Eucalypta the WickedWitch.
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* ComicStrip/{{Agent327}}: Hendrik IJzerbroot's most dangerous opponent is Boris Kloris.
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* ComicStrip/{{Agent327}}: ComicBook/{{Agent327}}: Hendrik IJzerbroot's most dangerous opponent is Boris Kloris.
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* {{Darkhawk}}
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* {{Darkhawk}}ComicBook/{{Darkhawk}}
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* ComicStrip/TomPoes: Bul Super and Hiep Hieper. Even though Joachim Sickbock and Hocus P. Pas are far more dangerous.
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* ComicStrip/TomPoes: ComicBook/TomPoes: Bul Super and Hiep Hieper. Even though Joachim Sickbock and Hocus P. Pas are far more dangerous.
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* ''ComicBook/{{Catwoman}}'' had Black Mask (the original version) as her arch-enemy in her early-2000s series. In a DarkerAndEdgier twist, she ended up murdering him after he tried to fridge her friends and relatives once too often.
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* Colonel Olrik is the Arch Enemy of BlakeAndMortimer.
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* ComicStrip/{{Tintin}}: Tintin's arch nemesis is Rastapopoulos.
* ComicStrip/QuickAndFlupke: Quick and Flupke are often confronted by Agent 15. Seeing that the two boys are brats your mileage may vary whether Agent 15 is actually the hero of the series or not.
* ComicStrip/BlakeAndMortimer: Blake and Mortimer often face off against Olrik.
* ComicStrip/SuskeEnWiske: Krimson is the main recurring villain.
* ComicStrip/{{Nero}}: In the early stories this role went to Matsuoka, a FuManchu like antagonist. Later Ricardo the Napolitan maffiosi became Nero's most frequent target.
* ComicStrip/{{Asterix}}: Julius Caesar would be this, even though there's a mutual respect between the Gauls and Caesar and they usually leave each other alone. Caesar is often seen as a VoiceOfReason and above the corruption of many of his legionnairies. He will defend the Gauls if he understands that some Romans have done them wrong in a way that even he couldn't defend.
* ComicStrip/{{Jommeke}}: Jommeke and his friends are often confronted by Anatool, the servant nobody can trust. However, he is somewhat of a HarmlessVillain, seeing that Jommeke and his friends can easily thwart his evil schemes. De Koningin van Onderland ("The Queen of Onderland") on the other hand doesn't appear that much in Jommeke's stories, but when she does she is generally considered to be his most frightening and dangerous opponent.
* ComicStrip/{{Agent327}}: Hendrik IJzerbroot's most dangerous opponent is Boris Kloris.
* ComicStrip/BuckDanny: Lady X.
* ComicStrip/LuckyLuke: Lucky Luke often faces off against the Daltons.
* ComicStrip/DeKiekeboes: Balthazar is the most recurring antagonist in the series, though generally considered to be a HarmlessVillain. Far more dangerous are Timothea Triangl- a BondVillain who underwent a sex change- and Dédé La Canaille, a criminal who wants to murder Kiekeboe for putting him into jail.
* ComicStrip/TheSmurfs: Gargamel who, in the comics at least, wants to turn the Smurfs into gold. In the animated series he simply wants to eat them.
* ComicStrip/TomPoes: Bul Super and Hiep Hieper. Even though Joachim Sickbock and Hocus P. Pas are far more dangerous.
* ComicStrip/DonaldDuck: Scrooge McDuck often combats the Beagle Boys. His business rival Flintheart Glimgold sometimes funcions as his own personal arch enemy too. However his most dangerous opponent is Magica Despell, who threatens to steal his lucky dime and melt it into the Vesuvius volcano.
** Similarly Donald Duck considers both Gladstone Gander and Neigbour Jones his personal arch enemies.
* ComicStrip/{{Urbanus}}: Urbanus often fights off against Jef Patat, a sleazy trickster.
* ComicStrip/QuickAndFlupke: Quick and Flupke are often confronted by Agent 15. Seeing that the two boys are brats your mileage may vary whether Agent 15 is actually the hero of the series or not.
* ComicStrip/BlakeAndMortimer: Blake and Mortimer often face off against Olrik.
* ComicStrip/SuskeEnWiske: Krimson is the main recurring villain.
* ComicStrip/{{Nero}}: In the early stories this role went to Matsuoka, a FuManchu like antagonist. Later Ricardo the Napolitan maffiosi became Nero's most frequent target.
* ComicStrip/{{Asterix}}: Julius Caesar would be this, even though there's a mutual respect between the Gauls and Caesar and they usually leave each other alone. Caesar is often seen as a VoiceOfReason and above the corruption of many of his legionnairies. He will defend the Gauls if he understands that some Romans have done them wrong in a way that even he couldn't defend.
* ComicStrip/{{Jommeke}}: Jommeke and his friends are often confronted by Anatool, the servant nobody can trust. However, he is somewhat of a HarmlessVillain, seeing that Jommeke and his friends can easily thwart his evil schemes. De Koningin van Onderland ("The Queen of Onderland") on the other hand doesn't appear that much in Jommeke's stories, but when she does she is generally considered to be his most frightening and dangerous opponent.
* ComicStrip/{{Agent327}}: Hendrik IJzerbroot's most dangerous opponent is Boris Kloris.
* ComicStrip/BuckDanny: Lady X.
* ComicStrip/LuckyLuke: Lucky Luke often faces off against the Daltons.
* ComicStrip/DeKiekeboes: Balthazar is the most recurring antagonist in the series, though generally considered to be a HarmlessVillain. Far more dangerous are Timothea Triangl- a BondVillain who underwent a sex change- and Dédé La Canaille, a criminal who wants to murder Kiekeboe for putting him into jail.
* ComicStrip/TheSmurfs: Gargamel who, in the comics at least, wants to turn the Smurfs into gold. In the animated series he simply wants to eat them.
* ComicStrip/TomPoes: Bul Super and Hiep Hieper. Even though Joachim Sickbock and Hocus P. Pas are far more dangerous.
* ComicStrip/DonaldDuck: Scrooge McDuck often combats the Beagle Boys. His business rival Flintheart Glimgold sometimes funcions as his own personal arch enemy too. However his most dangerous opponent is Magica Despell, who threatens to steal his lucky dime and melt it into the Vesuvius volcano.
** Similarly Donald Duck considers both Gladstone Gander and Neigbour Jones his personal arch enemies.
* ComicStrip/{{Urbanus}}: Urbanus often fights off against Jef Patat, a sleazy trickster.
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** TheKingpin (who would also be an impressive fourth place on Spidey's Arch Enemy list). As the ultimate gang boss, everything that Daredevil fights against can be traced back to him, and he's orchestrated several collapses of Matt's life, during "Born Again", "Devil In Cell Block D" and various other arcs, hurting him worse than anyone else ever has. As practically the {{deuteragonist}} of the series, Kingpin will always be a part of Matt Murdock's life for better or worse, a fact that his late wife Vanessa, comments on in-series.
to:
** TheKingpin (who would also be an impressive fourth place on Spidey's Arch Enemy list).list, as well as a contender for ThePunisher's). As the ultimate gang boss, everything that Daredevil fights against can be traced back to him, and he's orchestrated several collapses of Matt's life, during "Born Again", "Devil In Cell Block D" and various other arcs, hurting him worse than anyone else ever has. As practically the {{deuteragonist}} of the series, Kingpin will always be a part of Matt Murdock's life for better or worse, a fact that his late wife Vanessa, comments on in-series.
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** While he could be seen as the BigBad of the whole DC Universe, he definitely could fit this role for Superman, as he's the one villain bad enough to push Supes into a homicidal rage.
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** While he could be seen as the BigBad of the whole DC Universe, he {{Darkseid}} definitely could fit this role for Superman, as he's the one villain bad enough to push Supes into a homicidal rage.
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* Franchise/{{Superman}} has ComicBook/LexLuthor, {{Brainiac}} and General Zod.
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* Franchise/{{Superman}} has ComicBook/LexLuthor, {{Brainiac}} and {{Brainiac}}, General Zod.Zod, and {{Darkseid}}.
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** While he could be seen as the BigBad of the whole DC Universe, he definitely could fit this role for Superman, as he's the one villain bad enough to push Supes into a homicidal rage.
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* ComicBook/ThePunisher has Jigsaw. In The Punisher's case, "Arch Enemy" just means "enemy who's still alive". In the MAX imprint one could make a case for Barracuda for similar reasons.
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* ComicBook/ThePunisher has Jigsaw. In The Punisher's case, "Arch Enemy" just means "enemy who's still alive". In the [[ComicBook/ThePunisherMAX MAX imprint imprint]] one could make a case for Barracuda for similar reasons.
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* ComicBook/{{Magik}} and Belasco. Belasco turned Magik into what she is, and she has never stopped blaming him for this, and usurped him as ruler of Limbo. Eventually, Belasco's daughter took over this role for Magik.
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* ComicBook/{{Magik}} and Belasco. Belasco turned Magik into what she is, and she has never stopped blaming him for this, and usurped him as ruler of Limbo. Eventually, Belasco's daughter took over this role for Magik.Magik.
* ComicBook/JudgeDredd and Judge Death. The former is a trigger-happy fascist enforcer of a post-nuclear future, the latter a psychopathic undead monster from another dimension who wants to slaughter every living thing.
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* ComicBook/JudgeDredd and Judge Death. The former is a trigger-happy fascist enforcer of a post-nuclear future, the latter a psychopathic undead monster from another dimension who wants to slaughter every living thing.
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** Araña and Amun, formerly. Now Araña and Hobgoblin.
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** Araña and Amun, formerly. Now Araña and Hobgoblin.Hobgoblin (at least for a while).
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** Elixir and Wither.
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** Spider-Woman and Madame Hydra/Viper.
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** ComicBook/{{Magik}} and Belasco.
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* In ''ComicBook/{{Tomahawk}}'', the British Spy and MasterOfDisguise Lord Shilling was the arch-enemy of Tomahawk.
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* In ''ComicBook/{{Tomahawk}}'', the British Spy and MasterOfDisguise Lord Shilling was the arch-enemy of Tomahawk.Tomahawk.
* Matt Fraction's ''Hawkeye'' ongoing is seemingly setting up Madame Masque as Kate Bishop's arch-enemy. While it's for largely petty reasons (Kate tied her up and stole her identity for an issue), Masque has devoted an absurd amount fo time to wrecking Kate's life ever since.
* Spider-Woman and Madame Hydra/Viper, due to Jessica being raised by Hydra and possibly becoming the next Madame Hydra.
* From the ''New X-Men'', Elixir and Wither. Both were in a love triangle with Wallflower before she died, and have the opposite powers to one another. Elixer heals, Whither... whithers things.
* ComicBook/{{Magik}} and Belasco. Belasco turned Magik into what she is, and she has never stopped blaming him for this, and usurped him as ruler of Limbo. Eventually, Belasco's daughter took over this role for Magik.
* Matt Fraction's ''Hawkeye'' ongoing is seemingly setting up Madame Masque as Kate Bishop's arch-enemy. While it's for largely petty reasons (Kate tied her up and stole her identity for an issue), Masque has devoted an absurd amount fo time to wrecking Kate's life ever since.
* Spider-Woman and Madame Hydra/Viper, due to Jessica being raised by Hydra and possibly becoming the next Madame Hydra.
* From the ''New X-Men'', Elixir and Wither. Both were in a love triangle with Wallflower before she died, and have the opposite powers to one another. Elixer heals, Whither... whithers things.
* ComicBook/{{Magik}} and Belasco. Belasco turned Magik into what she is, and she has never stopped blaming him for this, and usurped him as ruler of Limbo. Eventually, Belasco's daughter took over this role for Magik.
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** [[Franchise/{{Marvel 2099}} Spider-Man 2099]] and Tyler Stone.
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** [[Franchise/{{Marvel 2099}} Spider-Man 2099]] ComicBook/SpiderMan2099 and Tyler Stone.
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* In ''ComicBook/{{Tomahawk}}'', the BritishSpy and MasterOfDisguise Lord Shilling was the arch-enemy of Tomahawk.
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* In ''ComicBook/{{Tomahawk}}'', the BritishSpy British Spy and MasterOfDisguise Lord Shilling was the arch-enemy of Tomahawk.
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* In the [[ComicBook/RobinSeries Robin comics of the 90's]], King Snake (the father of Bane) filled this role for Tim Drake.
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* In the [[ComicBook/RobinSeries Robin comics of the 90's]], King Snake (the father of Bane) filled this role for Tim Drake.Drake.
* In ''ComicBook/{{Tomahawk}}'', the BritishSpy and MasterOfDisguise Lord Shilling was the arch-enemy of Tomahawk.
* In ''ComicBook/{{Tomahawk}}'', the BritishSpy and MasterOfDisguise Lord Shilling was the arch-enemy of Tomahawk.
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Split from the main page due to length.
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* Most {{Super Hero}}es have one.
* Franchise/{{Superman}} has ComicBook/LexLuthor, {{Brainiac}} and General Zod.
** Lex Luthor is Superman's ultimate Arch Enemy and typically uses his brain against the Man of Steel's brawn, carefully avoiding any actions that could make Superman be justified in attacking him. To the point where only the muckraking [[SecretIdentityIdentity Clark Kent]], not Superman, can even put a scratch on Luthor. In ''ComicBook/InfiniteCrisis'', Alexander Luthor Jr. (son of a heroic alternate universe Luthor) eventually becomes convinced that one of the few things every universe has in common is that the resident Luthor and Superman (or Superman analogue) will always be archenemies.
** After Luthor, {{Brainiac}} comes in a close second, being one of the oldest villains in the rogues gallery, and certainly one of the most evil. He can match Superman blow-for-blow, shows up constantly, is [[TheDreaded feared by all Krytponians]] regularly endangers the world or even the multiverse, holds a Kryptonian city hostage, and recently killed Jonathan Kent. As one writer pointed out, he's the alien Superman isn't, an evil [[AlienInvasion otherworldy invader]] instead of a messianic refugee.
** General Zod is the Arch Enemy of Superman's father Jor-El, the one responsible for stopping his coup and imprisoning him in the Phantom Zone, with Superman inheriting the grudge. Following Superman's defeat of Zod in ''Last Son'' and the events of ''ComicBook/NewKrypton'', the rivalry turns very personal for the both of them.
** The Ultra-Humanite was originally designed to be Superman's arch-enemy - brilliant mind in a crippled body contrasting to the incredible physical might of Superman - but many of his traits were absorbed by fellow MadScientist Lex Luthor, and Ultra-Humanite rapidly faded from Superman's RoguesGallery and became a more general villain for DC.
** Post-Crisis ComicBook/{{Supergirl}} has [[NuclearNasty Reactron]]. Over the course of both her solo series, and the ''NewKrypton'' crossover, the two clashed repeatedly, leading to Reactron's murder of Supergirl's father, her mother Alura's ColdBloodedTorture of Reactron upon his capture, and the eventual destruction of New Krypton when Reactron blew up himself, the planet, and Kara's mother. For both of them the conflict was always personal.
* Franchise/{{Batman}} has Joker, Rā's al Ghūl, and Two-Face.
** SelfDemonstrating/TheJoker is Batman's Arch Enemy. His insanity and chaotic nature are the complete opposite of Batman's rigidly, even obsessively ordered intelligence. Though it's also their similarities. Both were shaped by great tragedy and loss (at least in the Joker's most commonly accepted origin story). Many people have said that Batman is just as insane as SelfDemonstrating/TheJoker, he just manifests it in a [[CrazySane different]] and more positive way and keeps control over it. SelfDemonstrating/TheJoker himself has pointed this out numerous times and in many adaptations.
----> '''SelfDemonstrating/TheJoker:''' [[ComicBook/TheKillingJoke "You had a bad day once, am I right?... Why else would you dress up like a flying rat?"]]
** ComicBook/RasAlGhul has a great deal of respect for Batman, may be even more dangerous, and a far larger scale threat, than the Joker, and is the father of one of Bruce's main love interests. If not the Arch Enemy, Ra's is definitely the main BigBad of Batman's enemies.
** ComicBook/TwoFace was once a great friend of Batman's, and is a personification of his failure. He's also got an ugly relationship with all of the Robins.
* The wrathful vengeance of SelfDemonstrating/DoctorDoom will never be sated! Never — until the earth runs red with the blood of that accursed '''[[ComicBook/FantasticFour REED RICHARDS!!]]'''
** The rest of the Fantastic Four as well, to a lesser extent. After he crushed Doom's hands, the Thing also jumped pretty high on his list.
* SelfDemonstrating/{{Sinestro}} is [[Comicbook/GreenLantern Hal Jordan's]] Arch Enemy; similarly, the [[Comicbook/GreenLantern Green Lantern Corps]] treat the Sinestro Corps as their most dangerous opposing organization (even though the Red Lanterns have the potential to go on homicidal rampages if left unchecked).
* Franchise/WonderWoman's is generally Circe or Cheetah, depending on who's writing. Ares gets in on the act too. He was, after all, her original [[TheGoldenAgeOfComicBooks Golden Age]] arch enemy, and is the biggest bad in her rogues gallery. As of Flashpoint Hera may be stepping into the role.
* Comicbook/{{Aquaman}}'s Arch Enemy spot is shared with [[CainAndAbel his brother]], Ocean Master and Black Manta.
** Depending on continuity the reasons behind Arthur and Orm's rivalry differs. But it usually revolves around the two brothers fighting over who is more fit to lead Atlantis. With Black Manta, their relationship is just full of mutual hatred.
* ComicBook/{{Deathstroke}} the Terminator is Robin/Nightwing's Arch Enemy. Of all the Titans, Slade hated Grayson the most. Whenever Slade and Grayson were in the same fight, regardless of how many others were involved, they nearly always went after each other. This animosity was ramped up immensely when Slade orchestrated the destruction of Blüdhaven, Nightwing's "Gotham" so to speak, and, when he, even more recently, cybernetically hijacked Damian Wayne's body in an attempt to kill Grayson. Deathstroke also harbors a grudge against Grayson for "[[HeelFaceTurn stealing his kids]]" from him
* ComicBook/{{Shazam}}: Things get interesting here, and a little complicated. Billy/Captain Marvel has usually considered Black Adam or Dr. Sivana to be his worst enemy. Freddy/Captain Marvel Jr. considers Captain Nazi, who killed his grandfather, to be his worst enemy. However, the archenemy of the Marvel family as a whole, and certainly the most dangerous of their foes, is telepathic Venusian worm, Mister Mind, who destroyed their hometown, brainwashed their friends, and murdered their cousin. Whenever Mind shows up, you can bet that the storyline will get darker, and Billy, Mary, and Freddy alike will take it very personally.
* Franchise/TheFlash. Flash varies from era to era.
** In the GoldenAge comics, it was the Thinker, who appeared more often than any other villain. In the SilverAge, it was Gorilla Grodd, who was the one exception in his roster of HarmlessVillain antagonists. In the BronzeAge it was Zoom/Reverse-Flash and his repeated attempts to outright steal his foe's life, who eventually [[spoiler: killed his wife.]] Wally West in the ModernAge had Vandal Savage at first, and later the acclaimed Mark Waid run boosted Abra Kadabra to this role by making that villain much DarkerAndEdgier. Finally, Geoff Johns promoted Captain Cold to leader of the rogues -- in the SilverAge it was usually the original Mirror Master or an outside villain in this role -- and also contributed a new Zoom as a contender for the role, another villain who was far too dangerous to join the Rogues. And now that Barry's back, it seems to be [[spoiler: the original Reverse-Flash again.]]
** Another candidate for Wally's Arch Enemy under Waid is Mirror Master II; much was made of his role as a second-generation villain "reflecting" Wally; he discovered the Mirror Dimension at the same time as Wally began channeling the Speed Force, and he was a member of Luthor's "All Archenemies" Injustice Gang.
* Then, the Justice League's arch-nemesis is the Legion of Doom/Injustice League/Injustice Gang.
** The Justice Society's arch-enemy is the Injustice Society of the World.
* Merlyn is considered ComicBook/GreenArrow's arch-enemy. Due to both being skilled archers on opposite sides of the law.
* ComicBook/CaptainAtom had General Wade Eiling. Although Cap [[MagnificentBastard didn't know that Eiling was his arch-enemy]].
* Franchise/{{Superman}} [[EvilCounterpart Prime]] possibly sees the fourth [[Franchise/TheFlash Flash]] (Bart Allen), the second [[Comicbook/GreenLantern Ion]] (Sodam Yat) and Kon-El, the cloned Superboy as his archenemies. Prime's new enemies, the WesternAnimation/LegionOfSuperHeroes might think so, too, [[spoiler:bringing back ''all three'' heroes (two BackFromTheDead, in fact) to combat Prime.]]
* ComicBook/JonahHex has Quentin Turnbull.
* [[ComicBook/NewGods Orion, Mister Miracle, and the Forever People]] all have Darkseid.
** Existence, all superheroes, all living beings, and every single universe in the history, future, present moment, or wiped timeline of reality has [[ComicBook/CrisisOnInfiniteEarths The Anti-Monitor]].
* The ComicBook/{{Legion Of Super-Heroes}} has three: Mordru, the Fatal Five, and the Legion of Super-Villains. The Fatal Five probably win the title for showing up the most often, but the L.S.V. has Lightning Lad's personal arch enemy Lightning Lord, and Mordru is ''certainly'' the most powerful of the three.
** The Time Trapper is another arch-enemy of the Legion.
* Franchise/SpiderMan has various Arch Enemies. Part of the reason this situation arises is that the Green Goblin [[ComicBookDeath died in the 70s]] and spent a good 20-odd years dead before he came back to torment his foe, which is probably the record for dead A-list villains to beat; it also means that Ock and Venom are arguably more famous, even though the Goblin is easily the most dangerous of the three. The other reason is that the Goblin, as Norman Osborn, suffered frequent bouts of amnesia in the run up to his death so he didn't even remember that he was Spidey's arch-enemy, which helped Doc Ock who was the next most formidable villain. Venom appeared in the 80s and made his chops by being in some ways a more personal (and visually stunning) enemy than either of the other two (that and overexposure). So essentially, Spidey has three arch-enemies because they kept replacing each other. However, since his return the Goblin has cemented himself as Spidey's one true Arch-foe.
** [[NormanOsborn The Green Goblin]]. Unlike most superhero arch-villains, he actually ''is'' the most dangerous foe of his enemy, possessing far greater resources and deep personal information (he was the first to discover Spider-Man's secret identity) that the others mostly all lack (though one could argue that, apart from Osborn killing Gwen Stacy, Venom was originally more [[ItsPersonal personal]] with his invasions of Peter Parker's life). There's also the whole "best friend's father" thing.
** DoctorOctopus: What Peter could end up becoming if he abused his intelligence and powers. (Peter was even a former student of his in [[WesternAnimation/SpiderManTheAnimatedSeries the animated series]]). Also the first villain to really defeat Spider-Man, completely shattering his confidence for a while, and is certainly the longest lasting and most recurring.
*** Currently with the [[DoNotGoGentle epic manouver]] [[ThanatosGambit Doc Ock]] [[GrandTheftMe has pulled]] he's arguably put himself on top of the list.
** ComicBook/{{Venom}}: EvilCounterpart. Not only is he effectively an even stronger version of Spidey himself, but Peter's SpiderSense doesn't work on him, which means Eddie / Venom could be right behind him without Peter knowing. Being bonded with the symbiote also gave Venom knowledge of Peter's secret identity, which Venom immediately used to scare Peter by harassing Mary Jane and Aunt May. Venom's initial grudge against him was kind of weak, but every adaptation makes it a lot more personal.
*** In addition to Spidey, Venom has Carnage, his son, as an arch-enemy. Spider-Man can't normally defeat Carnage on his own. The fact that Venom willingly comes to aid Spider-Man shows that he must hate Carnage more. Either that, or he just wants to be the one to deliver the killing blow.
* SelfDemonstrating/{{Magneto}} is Professor X's Arch Enemy, extending to the ComicBook/XMen. They are often actually [[FriendlyEnemy friendly enemies]].
** The Brotherhood of Evil Mutants serves as a collective Arch Enemy to the X-Men as a whole, though they have generally been replaced with more and more frightening mutant supremacists such as Mr. Sinister's Marauders, the Hellfire Club, or the various henchman of Apocalypse.
* ComicBook/{{Wolverine}}
** Sabretooth, as he represents Wolverine without any inhibitions, giving into his feral nature.
** [[AntagonisticOffspring Later, Logan's son]] {{Daken}}.
** A brave attempt was made to kill off Sabretooth and make new villain Romulus Wolverine's new arch-enemy, but it failed spectacularly.
* Mystique could be considered Rogue's arch-nemesis. Due to Rogue feeling like she's being used. And what she did to Ms. Marvel led her to leave Mystique's Brotherhood.
** For obvious reasons, Ms. Marvel can also be considered Mystique's Arch Enemy, in fact ''Ms. Marvel'' Vol. 2 #48-50 even refers to Mystique as Ms. Marvel's Arch Enemy.
*** Mystique also killed Ms. Marvel's then-lover towards the end of her first series. As for herself, Mystique may also consider the Shadow King her arch-enemy, seeing that he was responsible for her life-partner Destiny's death.
** Cyclops and his family have Sinister, who is obsessed with gaining control of the Summers bloodline, and has repeatedly used cloning and various other gambits to get said control. Scott takes this very personally.
* TheSentry's Arch Enemy is The Void, which is his own alternate personality. Complicated.
* ComicBook/AntMan's is ComicBook/{{Ultron}}, the rogue robot he created. Though the villain he's most likely to face by himself is probably Whirlwind. Since Ultron's programming is based on Ant-Man's own thought patterns, this also means that Ant-Man is his own worst enemy. Used to be Egghead...but he died.
* [[ComicBook/TheMightyThor Thor]] has ComicBook/{{Loki}}.
* Comicbook/DoctorStrange
** [[EvilCounterpart Baron Mordo]] formerly. The [[DimensionLord Dread Dormammu]] and Nightmare the lord of the Dream Dimension currently.
* ComicBook/CaptainAmerica has the RedSkull and the Barons Zemo (both the father and son).
* ComicBook/IronMan's traditional Arch Enemy was The Mandarin, but he's faded a bit over time as the YellowPeril aspect of the character is no longer kosher. Matt Fraction brought him back in big way during his run on ''Invincible Iron Man'', however, nicely cementing The Mandarin's status as the worst that Iron Man's rogues gallery has to offer.
** Seeing as thirteen different people have taken up the mantle, the Crimson Dynamo certainly is one of his most recurring and dangerous enemies, and has the best shot, after The Mandarin, of claiming this title. As a Communist holdout, the Dynamo also makes a useful counterpoint to Stark's capitalist ideology.
** During the eighties and nineties, and up until his apparent death in the early 2000s, [[CorruptCorporateExecutive evil industrialist]] Justin Hammer served as the archenemy of [[SecretIdentity Tony Stark]]. He was the mover and shaker behind "Demon in a Bottle", "Armour Wars I", and several other major arcs, and made repeated attempts to take down Stark Industries and their founder, all in order to increase his own profits. Hammer was one of the few villains Stark always took seriously, their hatred was definitely mutual, and in the end, his legacy lives on to this day in the form of his equally mad daughter and granddaughter.
* ComicBook/ThePunisher has Jigsaw. In The Punisher's case, "Arch Enemy" just means "enemy who's still alive". In the MAX imprint one could make a case for Barracuda for similar reasons.
* ComicBook/{{Daredevil}} has three modern day contenders.
** Bullseye. A PsychoForHire who typically acts as TheDragon to Kingpin, Bullseye's killed two of Matt Murdock's girlfriends, tried to kill his wife, Milla, and has generally dedicated himself to making Matt's life as hellish as possible; he's also inspired the likes of Lady Bullseye. In return, Matt wants Bullseye dead, and is willing to violate ThouShaltNotKill for him in a way he will for nobody else.
** TheKingpin (who would also be an impressive fourth place on Spidey's Arch Enemy list). As the ultimate gang boss, everything that Daredevil fights against can be traced back to him, and he's orchestrated several collapses of Matt's life, during "Born Again", "Devil In Cell Block D" and various other arcs, hurting him worse than anyone else ever has. As practically the {{deuteragonist}} of the series, Kingpin will always be a part of Matt Murdock's life for better or worse, a fact that his late wife Vanessa, comments on in-series.
** The {{ninja}} clan known as The Hand collectively fill the third slot on Matt's hit parade. They're among his most persistent enemies, many of his major foes (Elektra, Lady Bullseye, Kingpin) have either worked for them or tried to gain control of them at one point or another, they're the ultimate adversaries of his mentor, Stick, and worst of all, they want Matt to be their new leader. It's hard to get more personal than that.
** Originally, as written by Creator/StanLee, it was the Owl. These days, he's reduced to second-string status; while still dangerous he just doesn't carry the emotional weight that Bullseye, Kingpin, and The Hand do.
* ComicBook/SilverSurfer:
** {{Galactus}}, depending on the day of the week.
** Also Mephisto, who hates Norrin for just being so danged ''good.''
* The Sphinx and ComicBook/{{Nova}}.
* {{Sleepwalker}} and Cobweb.
* {{Darkhawk}}
** Mob boss Phillip Bazin, later replaced by Dargin Bokk, creator of the Darkhawk armor.
** And now replaced by Talon and possibly the whole Fraternity of Rapors, real creators of his armor.
* The ComicBook/BlackPanther and Klaw.
** There's also M'Baku, the Man-Ape, who is an EvilCounterpart to T'Challa for the White Gorilla cult.
* The Comicbook/IncredibleHulk
** The Leader.
** And The Abomination. And Gen. Thunderbolt Ross [[spoiler:who was revealed to be the [[EvilCounterpart Red Hulk]]]], bringing this feud to new, even more bitter heights.
** One could even make a case about Hulk being [[EnemyWithin Banner's.]]
* ComicBook/SheHulk had Titania.
* Ben Reilly's, aka the ComicBook/ScarletSpider, was Kaine...[[HeelFaceTurn now the current Scarlet Spider.]]
* SelfDemonstrating/{{Deadpool}} has T-Ray.
* RomSpaceknight and the Dire Wraiths.
* The Franchise/{{Micronauts}} and Baron Karza.
* ComicBook/CaptainMarVell had ComicBook/{{Thanos}}. Although Thanos did double duty as Adam Warlock's arch enemy, too. And he screwed with the ComicBook/SilverSurfer pretty seriously, too. After arcs like ''Infinity Gauntlet'' and other stories on that scale a case could be made that Thanos is the Arch Enemy of the Franchise/MarvelUniverse.
* The Octopus is the Arch Enemy of ComicBook/TheSpirit.
* Colonel Olrik is the Arch Enemy of BlakeAndMortimer.
* The Shredder to the Franchise/TeenageMutantNinjaTurtlesMirage and their [[TheObiWan Obi-Wan]] Master Splinter. Shredder goes down pretty early in the original comics. However the first issue clearly shows the backstory Splinter and Shredder have, that Splinter and the Turtles owe their origins to Shredder, and that Splinter trained the Turtles for the sole purpose of killing Shredder to avenge Hamato Yoshi. Regardless of how long Shredder was around for, he's still their archnemesis.
** The Arch Enemy dynamic is played interestingly in the story. After Shredder was killed, the Turtles never really had another central enemy. A few issues show that the Turtles aren't really sure what to do with themselves with Shredder gone. In fact, in the City At War arc that capped off the original series, Leonardo argues that killing Shredder was more Splinter's goal than theirs.
* AtomicRobo has the Nazi Baron Heinrich von Helsingard. Dr. Dinosaur may also qualify for Robo in modern times.
** Thomas Edison for Nikola Tesla and, by extension, Robo.
* One volume of ''ComicBook/{{Powers}}'' deconstructs the usual comic treatment of archenemies. It shows what were essentially the world's first superhero and supervillain. The two are immortal and have existed since humanity was still diverging from the ape, and have had a grudge just as long. When they meet for the last time in the present day, the hero, (who has a case of TheFogOfAges) demands to know why he and the villain have been fighting so long. The villain, whose memory is not impaired like the hero's, admits that he can no longer even remember what originally sparked their feud.
* While ''Comicbook/GreenLantern'' ''Rebirth'' and ''ComicBook/BlackestNight'' initially pegged Parallax as the Arch Enemy of ComicBook/TheSpectre, it seems that the Spectre's ''true'' nemesis is actually Butcher the Rage Entity. The Spectre exists to punish murderers, and Butcher is apparently the homicidal spawn of the first murder -- the embodiment of murderous rage.
* The Iron Major is Comicbook/SgtRock's Arch Enemy.
* Raven Red, an EvilCounterpart of Jet, is the only villain to appear more than once in ''Comicbook/JetDream''.
* ''ComicBook/SinCity'' villains usually don't live past their initial story but Manute has menaced Dwight [=McCarthy=] enough times to count. [[spoiler: Manute is dead now but he shows up anyway due to the nonlinear timeline.]]
** The Yellow Bastard did go up against Hartigan a few times before kicking the bucket. We only ended up seeing two confrontations in the same story, though.
* After becoming evil, being killed, and then brought back to life, Maxwell Lord has become the Arch Enemy to ComicBook/BoosterGold.
* As with the Brotherhood being the collective Arch Enemy of the X-Men, Comicbook/TheAvengers have the Masters of Evil.
** Kang is also arguably the Avengers' Arch Enemy.
* Baron Wolfgang von Strucker has served this mainly to ComicBook/NickFury, but also a bit to ComicBook/CaptainAmerica. Makes sense seeing as he's the leader of ComicBook/{{HYDRA}}.
* The Fabulous Frog-Man is a SuperZero wearing the PowerArmor of his father (ComicBook/{{Daredevil}} villain Leap Frog) which he cannot control so he just bounces around aimlessly and sometimes gets lucky. The White Rabbit is a ditzy {{Harmless Villain}}ess that read too much ''Literature/AliceInWonderland'' when she was a little girl and now dresses like a PlayboyBunny and pretends to be a Super Villainess despite having no powers or skills. They became each other’s arch-enemies because they are so pathetic nobody else would take them seriously.
* The ComicBook/MartianManhunter has had several contenders over the years including Commander Blanx and his {{expy}} (and J'onn's EvilTwin) Malefic. The best example, however, may well be GalacticConqueror and [[TheJuggernaut walking engine of destruction]], Despero. While Despero is usually a [[Franchise/JusticeLeagueOfAmerica Justice League]] calibre threat, J'onn is always the one he attacks first, and he takes a [[KickTheDog perverse delight]] in forcing the Martian to telepathically relive the destruction of Mars. At one point, Despero went so far as to MindRape J'onn into believing he was on a Mars that hadn't been destroyed by Blanx and/or Malefic...only to then invade the dream and personally slaughter the psychic constructs of J'onn's family that he had created. J'onn ''hates'' Despero about as much as he hates anyone, and is usually the JLA member who ends up having to put the crazed being down at the end of his rampages.
* In their fictional universe the characters from the two BritishComics ''ComicBook/TheBeano'' and ''ComicBook/TheDandy'' are arch enemies with frequent jokes but at the other's expense and infrequent raids between the comics. This arch enemy rivalry has died down quite alot since The Dandy's revamp. Also characters from within the two comics have their own arch enemies as well. ComicStrip/DennisTheMenaceUK has Walter the Softy, The Bash Street Kids had the Blob Street Kids, the Three Bears had Hank and Grizzly Gus (another more evil looking bear who hasnt been in the strip for years) and Desperate Dan had Dangerous Dan McGroo.
** This arch-enemy comic rivalry was taken UpToEleven in the Fleetway comic ''ComicBook/WhizzerAndChips'' which was one comic which was made up of two comics and these two comics and their characters were archenemies with even more frequent 'raids' in the two comics than with the Beano and Dandy
* Darkhell is this to [[ComicBook/LesLegendaires the Legendaries]], and this on ''soooo'' many levels: [[CreateYourOwnVillain he was the one who made part of them what they are now]], was the first threat they faced, fought them for several years, is the most recurring antagonist in the series and was the [[BigBad most dangerous]] [[TheDreaded of their enemies until]] [[BiggerBad Ana]][[GodOfEvil thos]] shew up. [[spoiler:Now that he finally died for real, it seems like his self-proclaimed heir Abyss is taking the mantle.]]
** Darkhell had his own arch-enemy, Skroa (though more of a [[TheRival Rival]] than an actual one) before the Legendaries formed, but ended up defeating him.
* ComicBook/GenerationX (specifically M, although he targeted the rest of the team as well) had Emplate.
* Comicbook/MoonKnight had Raoul Bushman, Marc Spector's commander in his mercenary days, who proved to be much more violent and ruthless.
* More Marvel archfoes:
** ComicBook/TheInhumans king Black Bolt's Arch Enemy is his [[CainAndAbel insane brother]], Maximus Boltagon the Mad. Currently (July 2012), the two have buried the hatchet, with Maximus loyally, if eccentrically, serving Black Bolt.
** Havok used to have the Living Monolith, who fed off Havok's power.
** Ex-mafioso [[ProfessionalKiller hitman]] Underworld's Arch Enemy was his traitorous, sociopathic brother, Mr. Pain, whom he killed.
** The Johnny Blaze/Zarathos incarnation of Comicbook/GhostRider's Arch Enemy is Mephisto.
** The Danny Ketch/Noble Kale incarnation of Ghost Rider's Arch Enemy is Blackheart.
** Shi'ar empress Lilandra Neramani and her sister Deathbird.
** Banshee and his cousin "Black Tom" Cassidy.
** Colossus and his brother Mikhail.
** Agent X and Black Swan.
** The Eric O'Grady Ant-Man and [[SociopathicSoldier Mitch Carson]].
** The ComicBook/SubMariner and Attuma.
*** Also Llyra, killer of Lady Dorma.
** The Arthurian-era Black Knight and Mordred.
** ComicBook/CaptainBritain and the first Slaymaster.
** Araña and Amun, formerly. Now Araña and Hobgoblin.
** Angel and Cameron Hodge.
** ComicBook/{{Cable}} and Apocalypse.
** ComicBook/{{Blade}} has Dracula and Deacon Frost (who also has Hannibal King).
** [[Franchise/{{Marvel 2099}} Spider-Man 2099]] and Tyler Stone.
** Beast and evil alternate self Dark Beast.
** Longshot and Mojo.
** The ComicBook/{{Runaways}} and the Pride, in particular Geoffrey Wilder.
** Merlin and Morgan le Fay.
** Doom 2099 and Tyger Wylde.
** Gravity and Black Death.
** The ComicBook/PowerPack and Snark leader Queen Mother Maraud.
** Ka-Zar and his brother the Plunderer.
** Spider-Man J and Lord Gokibu.
** Bishop and Trevor Fitzroy.
** Odin and Surtur.
** ComicBook/{{Elektra}} and Kirigi.
** [[ComicBook/ImmortalIronFist Iron Fist]] had Master Khan, now he has Steel Serpent.
** Moondragon and the Dragon of the Moon.
** The Guardian and Jerry Jaxon.
** {{X-23}} and Kimura.
** The Alana Jobson version of Jackpot "dibbed" the Goblin knockoff Menace as her Arch Enemy.
** ComicBook/{{Quasar}} and Maelstrom.
** [[ComicBook/NewAvengers The New Avengers]] and TheHood.
** Xavin and Commander Chrell.
** "Dum Dum" Dugan's archfoe was Godzilla, back when Marvel held Franchise/{{Godzilla}}'s comic license.
** Shang-Chi and Franchise/FuManchu, his father. Since Marvel no longer has Fu Manchu's license, he goes unnamed in his most recent appearances.
** Nightwatch and Warbringer.
** Annex and Brace.
** The Prowler and Nightcreeper.
** Solo and Deathstorm.
** The third ComicBook/SpiderWoman and Flesh and Bones.
** WonderMan and his brother, the Grim Reaper.
** ComicBook/HowardTheDuck and Dr. Bong.
** [[LukeCageHeroForHire Luke Cage]] and Chemistro.
** [[ComicBook/TheIncredibleHercules Hercules]] and ComicBook/{{Ares}}.
** Spider-Man 2211 and Hobgoblin 2211, his daughter.
** Amadeus Cho and Pythagoras Dupree.
** The Sarah Ehret version of Jackpot and the fourth Rose.
** ComicBook/JessicaJones and the Purple Man.
** ComicBook/{{Dazzler}} and Mortis.
** ComicBook/{{Hawkeye}} and Crossfire.
** Komodo and ex-boyfriend Hardball, [[FaceHeelTurn before he returned to good guys]].
** Elixir and Wither.
** Psylocke and Matsu'o Tsurayaba.
** Spider-Woman and Madame Hydra/Viper.
** New Mutant ComicBook/{{Warlock}} and his progenitor, Magus.
** Skaar and Hiro, the sons of Hulk.
** At one point, Kid Omega proclaimed No-Girl his Arch Enemy.
** The original Human Torch and the Mad Thinker.
** ComicBook/AdamWarlock and the Magus.
** ComicBook/{{Magik}} and Belasco.
** Ulysses Bloodstone and Ulluxy'l Kwan Tae Sy.
* Nothing can compare to what John Constantine the ''ComicBook/{{Hellblazer}}'' has. Having {{Satan}} as an arch-enemy is simply the worst.
* In ComicBook/SonicTheComic Sonic has two Arch-Enemies [[BigBad Doctor Robotnik]] and [[EnemyWithout Super Sonic]], Knuckles Arch-Enemy is [[MadScientist Doctor]] [[OmnicidalManiac Zachary]], [[EvilCounterpart Vermin]] [[MadeOfIndestructium the Cybernik]] is the Arch Enemy of [[OnlyKnownByTheirNickname Shortfuse]] [[MadeOfIndestructium the Cybernik]] and Tails' Arch-Enemy is Trogg.
** Sonic hatred of Robotnik increased after [[CreateYourOwnVillain Sonic Created Robotnik]].
* MickeyMouse as seen in more recent [[ComicBook/DisneyMouseAndDuckComics comics]] has his own kind of dynamic with his two arch enemies WesternAnimation/{{Pete}} and the Phantom Blot. Mickey is typically more or less an AmateurSleuth, naturally opposed to both of them as professional criminals. Pete is generally shown as a more crude but very experienced and enterprising criminal, whereas the Blot is a shadowy criminal mastermind. Pete [[EvenEvilHasStandards is not completely evil]] and has been shown with a kind of affection towards Mickey as an opponent and is more prone to end up in an EnemyMine situation with him, whereas the Blot is closer to being simply sociopathic. The two can even get contrasted in the same story, with Pete more human and the Blot more effortlessly smooth and evil. It's still DependingOnTheWriter.
* In the [[ComicBook/RobinSeries Robin comics of the 90's]], King Snake (the father of Bane) filled this role for Tim Drake.
* Franchise/{{Superman}} has ComicBook/LexLuthor, {{Brainiac}} and General Zod.
** Lex Luthor is Superman's ultimate Arch Enemy and typically uses his brain against the Man of Steel's brawn, carefully avoiding any actions that could make Superman be justified in attacking him. To the point where only the muckraking [[SecretIdentityIdentity Clark Kent]], not Superman, can even put a scratch on Luthor. In ''ComicBook/InfiniteCrisis'', Alexander Luthor Jr. (son of a heroic alternate universe Luthor) eventually becomes convinced that one of the few things every universe has in common is that the resident Luthor and Superman (or Superman analogue) will always be archenemies.
** After Luthor, {{Brainiac}} comes in a close second, being one of the oldest villains in the rogues gallery, and certainly one of the most evil. He can match Superman blow-for-blow, shows up constantly, is [[TheDreaded feared by all Krytponians]] regularly endangers the world or even the multiverse, holds a Kryptonian city hostage, and recently killed Jonathan Kent. As one writer pointed out, he's the alien Superman isn't, an evil [[AlienInvasion otherworldy invader]] instead of a messianic refugee.
** General Zod is the Arch Enemy of Superman's father Jor-El, the one responsible for stopping his coup and imprisoning him in the Phantom Zone, with Superman inheriting the grudge. Following Superman's defeat of Zod in ''Last Son'' and the events of ''ComicBook/NewKrypton'', the rivalry turns very personal for the both of them.
** The Ultra-Humanite was originally designed to be Superman's arch-enemy - brilliant mind in a crippled body contrasting to the incredible physical might of Superman - but many of his traits were absorbed by fellow MadScientist Lex Luthor, and Ultra-Humanite rapidly faded from Superman's RoguesGallery and became a more general villain for DC.
** Post-Crisis ComicBook/{{Supergirl}} has [[NuclearNasty Reactron]]. Over the course of both her solo series, and the ''NewKrypton'' crossover, the two clashed repeatedly, leading to Reactron's murder of Supergirl's father, her mother Alura's ColdBloodedTorture of Reactron upon his capture, and the eventual destruction of New Krypton when Reactron blew up himself, the planet, and Kara's mother. For both of them the conflict was always personal.
* Franchise/{{Batman}} has Joker, Rā's al Ghūl, and Two-Face.
** SelfDemonstrating/TheJoker is Batman's Arch Enemy. His insanity and chaotic nature are the complete opposite of Batman's rigidly, even obsessively ordered intelligence. Though it's also their similarities. Both were shaped by great tragedy and loss (at least in the Joker's most commonly accepted origin story). Many people have said that Batman is just as insane as SelfDemonstrating/TheJoker, he just manifests it in a [[CrazySane different]] and more positive way and keeps control over it. SelfDemonstrating/TheJoker himself has pointed this out numerous times and in many adaptations.
----> '''SelfDemonstrating/TheJoker:''' [[ComicBook/TheKillingJoke "You had a bad day once, am I right?... Why else would you dress up like a flying rat?"]]
** ComicBook/RasAlGhul has a great deal of respect for Batman, may be even more dangerous, and a far larger scale threat, than the Joker, and is the father of one of Bruce's main love interests. If not the Arch Enemy, Ra's is definitely the main BigBad of Batman's enemies.
** ComicBook/TwoFace was once a great friend of Batman's, and is a personification of his failure. He's also got an ugly relationship with all of the Robins.
* The wrathful vengeance of SelfDemonstrating/DoctorDoom will never be sated! Never — until the earth runs red with the blood of that accursed '''[[ComicBook/FantasticFour REED RICHARDS!!]]'''
** The rest of the Fantastic Four as well, to a lesser extent. After he crushed Doom's hands, the Thing also jumped pretty high on his list.
* SelfDemonstrating/{{Sinestro}} is [[Comicbook/GreenLantern Hal Jordan's]] Arch Enemy; similarly, the [[Comicbook/GreenLantern Green Lantern Corps]] treat the Sinestro Corps as their most dangerous opposing organization (even though the Red Lanterns have the potential to go on homicidal rampages if left unchecked).
* Franchise/WonderWoman's is generally Circe or Cheetah, depending on who's writing. Ares gets in on the act too. He was, after all, her original [[TheGoldenAgeOfComicBooks Golden Age]] arch enemy, and is the biggest bad in her rogues gallery. As of Flashpoint Hera may be stepping into the role.
* Comicbook/{{Aquaman}}'s Arch Enemy spot is shared with [[CainAndAbel his brother]], Ocean Master and Black Manta.
** Depending on continuity the reasons behind Arthur and Orm's rivalry differs. But it usually revolves around the two brothers fighting over who is more fit to lead Atlantis. With Black Manta, their relationship is just full of mutual hatred.
* ComicBook/{{Deathstroke}} the Terminator is Robin/Nightwing's Arch Enemy. Of all the Titans, Slade hated Grayson the most. Whenever Slade and Grayson were in the same fight, regardless of how many others were involved, they nearly always went after each other. This animosity was ramped up immensely when Slade orchestrated the destruction of Blüdhaven, Nightwing's "Gotham" so to speak, and, when he, even more recently, cybernetically hijacked Damian Wayne's body in an attempt to kill Grayson. Deathstroke also harbors a grudge against Grayson for "[[HeelFaceTurn stealing his kids]]" from him
* ComicBook/{{Shazam}}: Things get interesting here, and a little complicated. Billy/Captain Marvel has usually considered Black Adam or Dr. Sivana to be his worst enemy. Freddy/Captain Marvel Jr. considers Captain Nazi, who killed his grandfather, to be his worst enemy. However, the archenemy of the Marvel family as a whole, and certainly the most dangerous of their foes, is telepathic Venusian worm, Mister Mind, who destroyed their hometown, brainwashed their friends, and murdered their cousin. Whenever Mind shows up, you can bet that the storyline will get darker, and Billy, Mary, and Freddy alike will take it very personally.
* Franchise/TheFlash. Flash varies from era to era.
** In the GoldenAge comics, it was the Thinker, who appeared more often than any other villain. In the SilverAge, it was Gorilla Grodd, who was the one exception in his roster of HarmlessVillain antagonists. In the BronzeAge it was Zoom/Reverse-Flash and his repeated attempts to outright steal his foe's life, who eventually [[spoiler: killed his wife.]] Wally West in the ModernAge had Vandal Savage at first, and later the acclaimed Mark Waid run boosted Abra Kadabra to this role by making that villain much DarkerAndEdgier. Finally, Geoff Johns promoted Captain Cold to leader of the rogues -- in the SilverAge it was usually the original Mirror Master or an outside villain in this role -- and also contributed a new Zoom as a contender for the role, another villain who was far too dangerous to join the Rogues. And now that Barry's back, it seems to be [[spoiler: the original Reverse-Flash again.]]
** Another candidate for Wally's Arch Enemy under Waid is Mirror Master II; much was made of his role as a second-generation villain "reflecting" Wally; he discovered the Mirror Dimension at the same time as Wally began channeling the Speed Force, and he was a member of Luthor's "All Archenemies" Injustice Gang.
* Then, the Justice League's arch-nemesis is the Legion of Doom/Injustice League/Injustice Gang.
** The Justice Society's arch-enemy is the Injustice Society of the World.
* Merlyn is considered ComicBook/GreenArrow's arch-enemy. Due to both being skilled archers on opposite sides of the law.
* ComicBook/CaptainAtom had General Wade Eiling. Although Cap [[MagnificentBastard didn't know that Eiling was his arch-enemy]].
* Franchise/{{Superman}} [[EvilCounterpart Prime]] possibly sees the fourth [[Franchise/TheFlash Flash]] (Bart Allen), the second [[Comicbook/GreenLantern Ion]] (Sodam Yat) and Kon-El, the cloned Superboy as his archenemies. Prime's new enemies, the WesternAnimation/LegionOfSuperHeroes might think so, too, [[spoiler:bringing back ''all three'' heroes (two BackFromTheDead, in fact) to combat Prime.]]
* ComicBook/JonahHex has Quentin Turnbull.
* [[ComicBook/NewGods Orion, Mister Miracle, and the Forever People]] all have Darkseid.
** Existence, all superheroes, all living beings, and every single universe in the history, future, present moment, or wiped timeline of reality has [[ComicBook/CrisisOnInfiniteEarths The Anti-Monitor]].
* The ComicBook/{{Legion Of Super-Heroes}} has three: Mordru, the Fatal Five, and the Legion of Super-Villains. The Fatal Five probably win the title for showing up the most often, but the L.S.V. has Lightning Lad's personal arch enemy Lightning Lord, and Mordru is ''certainly'' the most powerful of the three.
** The Time Trapper is another arch-enemy of the Legion.
* Franchise/SpiderMan has various Arch Enemies. Part of the reason this situation arises is that the Green Goblin [[ComicBookDeath died in the 70s]] and spent a good 20-odd years dead before he came back to torment his foe, which is probably the record for dead A-list villains to beat; it also means that Ock and Venom are arguably more famous, even though the Goblin is easily the most dangerous of the three. The other reason is that the Goblin, as Norman Osborn, suffered frequent bouts of amnesia in the run up to his death so he didn't even remember that he was Spidey's arch-enemy, which helped Doc Ock who was the next most formidable villain. Venom appeared in the 80s and made his chops by being in some ways a more personal (and visually stunning) enemy than either of the other two (that and overexposure). So essentially, Spidey has three arch-enemies because they kept replacing each other. However, since his return the Goblin has cemented himself as Spidey's one true Arch-foe.
** [[NormanOsborn The Green Goblin]]. Unlike most superhero arch-villains, he actually ''is'' the most dangerous foe of his enemy, possessing far greater resources and deep personal information (he was the first to discover Spider-Man's secret identity) that the others mostly all lack (though one could argue that, apart from Osborn killing Gwen Stacy, Venom was originally more [[ItsPersonal personal]] with his invasions of Peter Parker's life). There's also the whole "best friend's father" thing.
** DoctorOctopus: What Peter could end up becoming if he abused his intelligence and powers. (Peter was even a former student of his in [[WesternAnimation/SpiderManTheAnimatedSeries the animated series]]). Also the first villain to really defeat Spider-Man, completely shattering his confidence for a while, and is certainly the longest lasting and most recurring.
*** Currently with the [[DoNotGoGentle epic manouver]] [[ThanatosGambit Doc Ock]] [[GrandTheftMe has pulled]] he's arguably put himself on top of the list.
** ComicBook/{{Venom}}: EvilCounterpart. Not only is he effectively an even stronger version of Spidey himself, but Peter's SpiderSense doesn't work on him, which means Eddie / Venom could be right behind him without Peter knowing. Being bonded with the symbiote also gave Venom knowledge of Peter's secret identity, which Venom immediately used to scare Peter by harassing Mary Jane and Aunt May. Venom's initial grudge against him was kind of weak, but every adaptation makes it a lot more personal.
*** In addition to Spidey, Venom has Carnage, his son, as an arch-enemy. Spider-Man can't normally defeat Carnage on his own. The fact that Venom willingly comes to aid Spider-Man shows that he must hate Carnage more. Either that, or he just wants to be the one to deliver the killing blow.
* SelfDemonstrating/{{Magneto}} is Professor X's Arch Enemy, extending to the ComicBook/XMen. They are often actually [[FriendlyEnemy friendly enemies]].
** The Brotherhood of Evil Mutants serves as a collective Arch Enemy to the X-Men as a whole, though they have generally been replaced with more and more frightening mutant supremacists such as Mr. Sinister's Marauders, the Hellfire Club, or the various henchman of Apocalypse.
* ComicBook/{{Wolverine}}
** Sabretooth, as he represents Wolverine without any inhibitions, giving into his feral nature.
** [[AntagonisticOffspring Later, Logan's son]] {{Daken}}.
** A brave attempt was made to kill off Sabretooth and make new villain Romulus Wolverine's new arch-enemy, but it failed spectacularly.
* Mystique could be considered Rogue's arch-nemesis. Due to Rogue feeling like she's being used. And what she did to Ms. Marvel led her to leave Mystique's Brotherhood.
** For obvious reasons, Ms. Marvel can also be considered Mystique's Arch Enemy, in fact ''Ms. Marvel'' Vol. 2 #48-50 even refers to Mystique as Ms. Marvel's Arch Enemy.
*** Mystique also killed Ms. Marvel's then-lover towards the end of her first series. As for herself, Mystique may also consider the Shadow King her arch-enemy, seeing that he was responsible for her life-partner Destiny's death.
** Cyclops and his family have Sinister, who is obsessed with gaining control of the Summers bloodline, and has repeatedly used cloning and various other gambits to get said control. Scott takes this very personally.
* TheSentry's Arch Enemy is The Void, which is his own alternate personality. Complicated.
* ComicBook/AntMan's is ComicBook/{{Ultron}}, the rogue robot he created. Though the villain he's most likely to face by himself is probably Whirlwind. Since Ultron's programming is based on Ant-Man's own thought patterns, this also means that Ant-Man is his own worst enemy. Used to be Egghead...but he died.
* [[ComicBook/TheMightyThor Thor]] has ComicBook/{{Loki}}.
* Comicbook/DoctorStrange
** [[EvilCounterpart Baron Mordo]] formerly. The [[DimensionLord Dread Dormammu]] and Nightmare the lord of the Dream Dimension currently.
* ComicBook/CaptainAmerica has the RedSkull and the Barons Zemo (both the father and son).
* ComicBook/IronMan's traditional Arch Enemy was The Mandarin, but he's faded a bit over time as the YellowPeril aspect of the character is no longer kosher. Matt Fraction brought him back in big way during his run on ''Invincible Iron Man'', however, nicely cementing The Mandarin's status as the worst that Iron Man's rogues gallery has to offer.
** Seeing as thirteen different people have taken up the mantle, the Crimson Dynamo certainly is one of his most recurring and dangerous enemies, and has the best shot, after The Mandarin, of claiming this title. As a Communist holdout, the Dynamo also makes a useful counterpoint to Stark's capitalist ideology.
** During the eighties and nineties, and up until his apparent death in the early 2000s, [[CorruptCorporateExecutive evil industrialist]] Justin Hammer served as the archenemy of [[SecretIdentity Tony Stark]]. He was the mover and shaker behind "Demon in a Bottle", "Armour Wars I", and several other major arcs, and made repeated attempts to take down Stark Industries and their founder, all in order to increase his own profits. Hammer was one of the few villains Stark always took seriously, their hatred was definitely mutual, and in the end, his legacy lives on to this day in the form of his equally mad daughter and granddaughter.
* ComicBook/ThePunisher has Jigsaw. In The Punisher's case, "Arch Enemy" just means "enemy who's still alive". In the MAX imprint one could make a case for Barracuda for similar reasons.
* ComicBook/{{Daredevil}} has three modern day contenders.
** Bullseye. A PsychoForHire who typically acts as TheDragon to Kingpin, Bullseye's killed two of Matt Murdock's girlfriends, tried to kill his wife, Milla, and has generally dedicated himself to making Matt's life as hellish as possible; he's also inspired the likes of Lady Bullseye. In return, Matt wants Bullseye dead, and is willing to violate ThouShaltNotKill for him in a way he will for nobody else.
** TheKingpin (who would also be an impressive fourth place on Spidey's Arch Enemy list). As the ultimate gang boss, everything that Daredevil fights against can be traced back to him, and he's orchestrated several collapses of Matt's life, during "Born Again", "Devil In Cell Block D" and various other arcs, hurting him worse than anyone else ever has. As practically the {{deuteragonist}} of the series, Kingpin will always be a part of Matt Murdock's life for better or worse, a fact that his late wife Vanessa, comments on in-series.
** The {{ninja}} clan known as The Hand collectively fill the third slot on Matt's hit parade. They're among his most persistent enemies, many of his major foes (Elektra, Lady Bullseye, Kingpin) have either worked for them or tried to gain control of them at one point or another, they're the ultimate adversaries of his mentor, Stick, and worst of all, they want Matt to be their new leader. It's hard to get more personal than that.
** Originally, as written by Creator/StanLee, it was the Owl. These days, he's reduced to second-string status; while still dangerous he just doesn't carry the emotional weight that Bullseye, Kingpin, and The Hand do.
* ComicBook/SilverSurfer:
** {{Galactus}}, depending on the day of the week.
** Also Mephisto, who hates Norrin for just being so danged ''good.''
* The Sphinx and ComicBook/{{Nova}}.
* {{Sleepwalker}} and Cobweb.
* {{Darkhawk}}
** Mob boss Phillip Bazin, later replaced by Dargin Bokk, creator of the Darkhawk armor.
** And now replaced by Talon and possibly the whole Fraternity of Rapors, real creators of his armor.
* The ComicBook/BlackPanther and Klaw.
** There's also M'Baku, the Man-Ape, who is an EvilCounterpart to T'Challa for the White Gorilla cult.
* The Comicbook/IncredibleHulk
** The Leader.
** And The Abomination. And Gen. Thunderbolt Ross [[spoiler:who was revealed to be the [[EvilCounterpart Red Hulk]]]], bringing this feud to new, even more bitter heights.
** One could even make a case about Hulk being [[EnemyWithin Banner's.]]
* ComicBook/SheHulk had Titania.
* Ben Reilly's, aka the ComicBook/ScarletSpider, was Kaine...[[HeelFaceTurn now the current Scarlet Spider.]]
* SelfDemonstrating/{{Deadpool}} has T-Ray.
* RomSpaceknight and the Dire Wraiths.
* The Franchise/{{Micronauts}} and Baron Karza.
* ComicBook/CaptainMarVell had ComicBook/{{Thanos}}. Although Thanos did double duty as Adam Warlock's arch enemy, too. And he screwed with the ComicBook/SilverSurfer pretty seriously, too. After arcs like ''Infinity Gauntlet'' and other stories on that scale a case could be made that Thanos is the Arch Enemy of the Franchise/MarvelUniverse.
* The Octopus is the Arch Enemy of ComicBook/TheSpirit.
* Colonel Olrik is the Arch Enemy of BlakeAndMortimer.
* The Shredder to the Franchise/TeenageMutantNinjaTurtlesMirage and their [[TheObiWan Obi-Wan]] Master Splinter. Shredder goes down pretty early in the original comics. However the first issue clearly shows the backstory Splinter and Shredder have, that Splinter and the Turtles owe their origins to Shredder, and that Splinter trained the Turtles for the sole purpose of killing Shredder to avenge Hamato Yoshi. Regardless of how long Shredder was around for, he's still their archnemesis.
** The Arch Enemy dynamic is played interestingly in the story. After Shredder was killed, the Turtles never really had another central enemy. A few issues show that the Turtles aren't really sure what to do with themselves with Shredder gone. In fact, in the City At War arc that capped off the original series, Leonardo argues that killing Shredder was more Splinter's goal than theirs.
* AtomicRobo has the Nazi Baron Heinrich von Helsingard. Dr. Dinosaur may also qualify for Robo in modern times.
** Thomas Edison for Nikola Tesla and, by extension, Robo.
* One volume of ''ComicBook/{{Powers}}'' deconstructs the usual comic treatment of archenemies. It shows what were essentially the world's first superhero and supervillain. The two are immortal and have existed since humanity was still diverging from the ape, and have had a grudge just as long. When they meet for the last time in the present day, the hero, (who has a case of TheFogOfAges) demands to know why he and the villain have been fighting so long. The villain, whose memory is not impaired like the hero's, admits that he can no longer even remember what originally sparked their feud.
* While ''Comicbook/GreenLantern'' ''Rebirth'' and ''ComicBook/BlackestNight'' initially pegged Parallax as the Arch Enemy of ComicBook/TheSpectre, it seems that the Spectre's ''true'' nemesis is actually Butcher the Rage Entity. The Spectre exists to punish murderers, and Butcher is apparently the homicidal spawn of the first murder -- the embodiment of murderous rage.
* The Iron Major is Comicbook/SgtRock's Arch Enemy.
* Raven Red, an EvilCounterpart of Jet, is the only villain to appear more than once in ''Comicbook/JetDream''.
* ''ComicBook/SinCity'' villains usually don't live past their initial story but Manute has menaced Dwight [=McCarthy=] enough times to count. [[spoiler: Manute is dead now but he shows up anyway due to the nonlinear timeline.]]
** The Yellow Bastard did go up against Hartigan a few times before kicking the bucket. We only ended up seeing two confrontations in the same story, though.
* After becoming evil, being killed, and then brought back to life, Maxwell Lord has become the Arch Enemy to ComicBook/BoosterGold.
* As with the Brotherhood being the collective Arch Enemy of the X-Men, Comicbook/TheAvengers have the Masters of Evil.
** Kang is also arguably the Avengers' Arch Enemy.
* Baron Wolfgang von Strucker has served this mainly to ComicBook/NickFury, but also a bit to ComicBook/CaptainAmerica. Makes sense seeing as he's the leader of ComicBook/{{HYDRA}}.
* The Fabulous Frog-Man is a SuperZero wearing the PowerArmor of his father (ComicBook/{{Daredevil}} villain Leap Frog) which he cannot control so he just bounces around aimlessly and sometimes gets lucky. The White Rabbit is a ditzy {{Harmless Villain}}ess that read too much ''Literature/AliceInWonderland'' when she was a little girl and now dresses like a PlayboyBunny and pretends to be a Super Villainess despite having no powers or skills. They became each other’s arch-enemies because they are so pathetic nobody else would take them seriously.
* The ComicBook/MartianManhunter has had several contenders over the years including Commander Blanx and his {{expy}} (and J'onn's EvilTwin) Malefic. The best example, however, may well be GalacticConqueror and [[TheJuggernaut walking engine of destruction]], Despero. While Despero is usually a [[Franchise/JusticeLeagueOfAmerica Justice League]] calibre threat, J'onn is always the one he attacks first, and he takes a [[KickTheDog perverse delight]] in forcing the Martian to telepathically relive the destruction of Mars. At one point, Despero went so far as to MindRape J'onn into believing he was on a Mars that hadn't been destroyed by Blanx and/or Malefic...only to then invade the dream and personally slaughter the psychic constructs of J'onn's family that he had created. J'onn ''hates'' Despero about as much as he hates anyone, and is usually the JLA member who ends up having to put the crazed being down at the end of his rampages.
* In their fictional universe the characters from the two BritishComics ''ComicBook/TheBeano'' and ''ComicBook/TheDandy'' are arch enemies with frequent jokes but at the other's expense and infrequent raids between the comics. This arch enemy rivalry has died down quite alot since The Dandy's revamp. Also characters from within the two comics have their own arch enemies as well. ComicStrip/DennisTheMenaceUK has Walter the Softy, The Bash Street Kids had the Blob Street Kids, the Three Bears had Hank and Grizzly Gus (another more evil looking bear who hasnt been in the strip for years) and Desperate Dan had Dangerous Dan McGroo.
** This arch-enemy comic rivalry was taken UpToEleven in the Fleetway comic ''ComicBook/WhizzerAndChips'' which was one comic which was made up of two comics and these two comics and their characters were archenemies with even more frequent 'raids' in the two comics than with the Beano and Dandy
* Darkhell is this to [[ComicBook/LesLegendaires the Legendaries]], and this on ''soooo'' many levels: [[CreateYourOwnVillain he was the one who made part of them what they are now]], was the first threat they faced, fought them for several years, is the most recurring antagonist in the series and was the [[BigBad most dangerous]] [[TheDreaded of their enemies until]] [[BiggerBad Ana]][[GodOfEvil thos]] shew up. [[spoiler:Now that he finally died for real, it seems like his self-proclaimed heir Abyss is taking the mantle.]]
** Darkhell had his own arch-enemy, Skroa (though more of a [[TheRival Rival]] than an actual one) before the Legendaries formed, but ended up defeating him.
* ComicBook/GenerationX (specifically M, although he targeted the rest of the team as well) had Emplate.
* Comicbook/MoonKnight had Raoul Bushman, Marc Spector's commander in his mercenary days, who proved to be much more violent and ruthless.
* More Marvel archfoes:
** ComicBook/TheInhumans king Black Bolt's Arch Enemy is his [[CainAndAbel insane brother]], Maximus Boltagon the Mad. Currently (July 2012), the two have buried the hatchet, with Maximus loyally, if eccentrically, serving Black Bolt.
** Havok used to have the Living Monolith, who fed off Havok's power.
** Ex-mafioso [[ProfessionalKiller hitman]] Underworld's Arch Enemy was his traitorous, sociopathic brother, Mr. Pain, whom he killed.
** The Johnny Blaze/Zarathos incarnation of Comicbook/GhostRider's Arch Enemy is Mephisto.
** The Danny Ketch/Noble Kale incarnation of Ghost Rider's Arch Enemy is Blackheart.
** Shi'ar empress Lilandra Neramani and her sister Deathbird.
** Banshee and his cousin "Black Tom" Cassidy.
** Colossus and his brother Mikhail.
** Agent X and Black Swan.
** The Eric O'Grady Ant-Man and [[SociopathicSoldier Mitch Carson]].
** The ComicBook/SubMariner and Attuma.
*** Also Llyra, killer of Lady Dorma.
** The Arthurian-era Black Knight and Mordred.
** ComicBook/CaptainBritain and the first Slaymaster.
** Araña and Amun, formerly. Now Araña and Hobgoblin.
** Angel and Cameron Hodge.
** ComicBook/{{Cable}} and Apocalypse.
** ComicBook/{{Blade}} has Dracula and Deacon Frost (who also has Hannibal King).
** [[Franchise/{{Marvel 2099}} Spider-Man 2099]] and Tyler Stone.
** Beast and evil alternate self Dark Beast.
** Longshot and Mojo.
** The ComicBook/{{Runaways}} and the Pride, in particular Geoffrey Wilder.
** Merlin and Morgan le Fay.
** Doom 2099 and Tyger Wylde.
** Gravity and Black Death.
** The ComicBook/PowerPack and Snark leader Queen Mother Maraud.
** Ka-Zar and his brother the Plunderer.
** Spider-Man J and Lord Gokibu.
** Bishop and Trevor Fitzroy.
** Odin and Surtur.
** ComicBook/{{Elektra}} and Kirigi.
** [[ComicBook/ImmortalIronFist Iron Fist]] had Master Khan, now he has Steel Serpent.
** Moondragon and the Dragon of the Moon.
** The Guardian and Jerry Jaxon.
** {{X-23}} and Kimura.
** The Alana Jobson version of Jackpot "dibbed" the Goblin knockoff Menace as her Arch Enemy.
** ComicBook/{{Quasar}} and Maelstrom.
** [[ComicBook/NewAvengers The New Avengers]] and TheHood.
** Xavin and Commander Chrell.
** "Dum Dum" Dugan's archfoe was Godzilla, back when Marvel held Franchise/{{Godzilla}}'s comic license.
** Shang-Chi and Franchise/FuManchu, his father. Since Marvel no longer has Fu Manchu's license, he goes unnamed in his most recent appearances.
** Nightwatch and Warbringer.
** Annex and Brace.
** The Prowler and Nightcreeper.
** Solo and Deathstorm.
** The third ComicBook/SpiderWoman and Flesh and Bones.
** WonderMan and his brother, the Grim Reaper.
** ComicBook/HowardTheDuck and Dr. Bong.
** [[LukeCageHeroForHire Luke Cage]] and Chemistro.
** [[ComicBook/TheIncredibleHercules Hercules]] and ComicBook/{{Ares}}.
** Spider-Man 2211 and Hobgoblin 2211, his daughter.
** Amadeus Cho and Pythagoras Dupree.
** The Sarah Ehret version of Jackpot and the fourth Rose.
** ComicBook/JessicaJones and the Purple Man.
** ComicBook/{{Dazzler}} and Mortis.
** ComicBook/{{Hawkeye}} and Crossfire.
** Komodo and ex-boyfriend Hardball, [[FaceHeelTurn before he returned to good guys]].
** Elixir and Wither.
** Psylocke and Matsu'o Tsurayaba.
** Spider-Woman and Madame Hydra/Viper.
** New Mutant ComicBook/{{Warlock}} and his progenitor, Magus.
** Skaar and Hiro, the sons of Hulk.
** At one point, Kid Omega proclaimed No-Girl his Arch Enemy.
** The original Human Torch and the Mad Thinker.
** ComicBook/AdamWarlock and the Magus.
** ComicBook/{{Magik}} and Belasco.
** Ulysses Bloodstone and Ulluxy'l Kwan Tae Sy.
* Nothing can compare to what John Constantine the ''ComicBook/{{Hellblazer}}'' has. Having {{Satan}} as an arch-enemy is simply the worst.
* In ComicBook/SonicTheComic Sonic has two Arch-Enemies [[BigBad Doctor Robotnik]] and [[EnemyWithout Super Sonic]], Knuckles Arch-Enemy is [[MadScientist Doctor]] [[OmnicidalManiac Zachary]], [[EvilCounterpart Vermin]] [[MadeOfIndestructium the Cybernik]] is the Arch Enemy of [[OnlyKnownByTheirNickname Shortfuse]] [[MadeOfIndestructium the Cybernik]] and Tails' Arch-Enemy is Trogg.
** Sonic hatred of Robotnik increased after [[CreateYourOwnVillain Sonic Created Robotnik]].
* MickeyMouse as seen in more recent [[ComicBook/DisneyMouseAndDuckComics comics]] has his own kind of dynamic with his two arch enemies WesternAnimation/{{Pete}} and the Phantom Blot. Mickey is typically more or less an AmateurSleuth, naturally opposed to both of them as professional criminals. Pete is generally shown as a more crude but very experienced and enterprising criminal, whereas the Blot is a shadowy criminal mastermind. Pete [[EvenEvilHasStandards is not completely evil]] and has been shown with a kind of affection towards Mickey as an opponent and is more prone to end up in an EnemyMine situation with him, whereas the Blot is closer to being simply sociopathic. The two can even get contrasted in the same story, with Pete more human and the Blot more effortlessly smooth and evil. It's still DependingOnTheWriter.
* In the [[ComicBook/RobinSeries Robin comics of the 90's]], King Snake (the father of Bane) filled this role for Tim Drake.
