Eh, some come close, but a seeable brain is ridiculous enough.
Anyway, I love her tank design in the show, and think that if she was playable, that'd be the best version. Of course, that won't happen unless somehow Captain N could get in.
I kind of like her bipedal design, but not as much. If only because a "brain in a tank" sounds far more interesting than just another typical one-eye bipedal strong monster. Albeit, her Prime design still kicks tons of ass, but I'm not sure she'd make a great character who kicks ass. That version anyway.
I'd still prefer Ridley in Smash first. More appearances, is a personal character to Samus, more characterization, and is another dragon.