These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
What Do You Mean, It Wasn't Made on Drugs?: The creators have answered this in interviews, pointing out that Williams Street, like all corporations, has a drug policy. Though, when asked whether they make the show while drunk, they simply say they're always drunk.