- Harsher in Hindsight: The episode "Puffless" would eventually reveal that Lisa's maternal grandfather, Clancy Bouvier, died of lung cancer, something most of his family wasn't aware of. It's probably a good thing Homer stepped in when he did.
- Unintentional Period Piece:
- The family attending the midnight release of the final "Angelica Button" book references the release of Harry Potter and the Deathly Hallows the year the episode was produced.
- Lisa's point of reference for how bad smoking is is an episode of The Suite Life of Zack & Cody, a show that was on air for the latter half of The 2000s and would have been popular among Lisa's age group.
http://tvtropes.org/pmwiki/pmwiki.php/YMMV/TheSimpsonsS19E15SmokeOnTheDaughter
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