These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
The Woobie: Holmes. Early on, Watson overshoots his bounds with a question about Holmes's past, and Holmes, previously in decent humor, gets cool and goes to his room. Later on, the man himself tells Madame Valladon that his fiancee died just a day before the wedding. He seems to have gotten over it, but the fact remains that he was that close to getting married once. The end simply tops it off, and Watson isn't about to deny him his cocaine.