* AlternativeCharacterInterpretation: The main character can be interpreted as a virus invading Eden's mainframe, made popular by [[Creator/{{Toonami}} SARA]]'s review of the game.
* CrowningMusicOfAwesome: Pretty much the entire game, but the notable standouts include Stage 3 (Ken Ishii's "Creation (The State of Art)") and Stage 5 (Adam Freeland's "Fear (Don's Magical Adventure Mix)", which [[{{Sampling}} samples]] its main riff from Marlena Shaw's version of "California Soul").
** DoubleSubverted with the Area 4 music ("ROCK IS SPONGE"). For most of the level, you get a cool, percussion-heavy piece. Then, out of nowhere, a random electric guitar appears in the boss. At first this seems jarring... but then you put the rest of the level out of your mind... [[CrowningMomentOfAwesome and realize that the boss music is AWESOME.]]
** Hydelic's [[https://www.youtube.com/watch?v=e4DBcmuMVbs trance mix]], created for the new Area X in ''Rez Infinite'', encompasses various genres of trance, ending with a beautiful vocal piece for the credits.
* FridgeHorror: Eden is shutting itself down because it's under so much stress from trying to handle so much information, and a virus infected her. You're tasked with...forcing it back into duty.
** However, she does ask you to save her right before the final boss and thanks you in the white butterfly ending's post-credits message.
* MemeticMutation: Eden doubting her existence, to the point where fans portray her as having an existential crisis over ''anything'', even stupid things like finding out there's no pizza left.
* PlayTheGameSkipTheStory: [[AttentionDeficitOohShiny Ooh, pretty lights!]]
* ThisIsYourPremiseOnDrugs: The game has been likened to ''{{TRON}}'' on ecstasy.
* WatchItForTheMeme: The game got more publicity from the fact the Japanese version came with a freaking vibrator.
* WhatDoYouMeanItsNotSymbolic: The AI's name is Eden. Area 5 is a tour of the evolution of life from single-celled organisms, to sea life, to the migration to land, and ultimately, either leaving Earth to colonize other planets or the [[AscendToAHigherPlaneOfExistence Ascent To A Higher Plane Of Existence]] (depending on your interpretation).
* WhatDoYouMeanItWasntMadeOnDrugs: A common reaction to seeing gameplay footage.