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  • Complete Monster: Zachary Barrows and Nathaniel Cade have faced some nasty villains in their quest to protect the United States with these the worst:
    • Dr. Johann Konrad Dippel is an Evilutionary Biologist, the inspiration for Victor Frankenstein and the Arch-Enemy of Nathaniel Cade. With centuries of wicked and painful experimentation on humans, Konrad also harvests people for spare parts to keep himself eternally young, which is showcased when he mutilates a young prostitute he frequents and tricks her into surrendering to death so he may use her life for his. When her pimp comes by, Konrad infects him with an agonizing flu strain he perfected, also intending on unleashing a Zombie Apocalypse on the USA, killing countless people, even betraying his co-conspirator Helen Holt by infecting her with an agent to leave her permanently paralyzed and never aging. Escaping, Konrad begins selling his services to terrorist groups to utilize his strains and agents to kill more people for the highest bidder.
    • Helen Holt is a born sociopath, one of the worst that the Shadow Company has to offer and the nemesis of Zachary Burrows. A vain monster who showed her true colours in the CIA by betraying her team to the Islamic extremists they were observing because she felt they were deliberately sidelining her, Helen allies with the vile Konrad and helps in his attempt to attack the United States with a zombie army in return for eternal life and beauty. After Zachary and Cade insult her, she plots her terrible revenge on them due to the perceived slight. Allying with the ancient Serial Killer monster known as the Bogeyman, she helps it in a murder spree that kills countless people in brutal mutilations and horrific murders. Her ultimate goal is to have it murder the U.S. President's daughter and young son as the ultimate way to get back at Cade by seeing him fail at his life's work.
    • The President's Vampire (second book): Colonel Graves, real name Peter Sinclair, is a high-ranking member of the Shadow Company and the man who had President Kennedy assassinated. Finagling a pardon, Graves also subjects many people to horrific experimentation with the Snakehead virus to mutate many others into reptilian monsters which he feeds with innocents and others, kidnapping many people to experiment on, from terrorists to college kids who just wore the wrong shirt. Graves intends to start "doomsday" by unleashing them on the population of the heartland, even taking children and making them into brain-dead incubators for the virus.
  • Squick: Nikki's pimp is infected with a fast-working virus that turns all of his body into a material to build its own body, this being a creepy fungi-like thing with plant-like tendrils and reptilian, scaled skin. Before this happens, he has giant warts all over his body (including on eyelids) that blow to make way for the scaly hide.


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