YMMV / Mystery Diagnosis

• Nightmare Fuel: If you're skittish about doctors and/or medical procedures, the entire show is this.
  • Some examples of music in the show could be this. Of particular note is a synthesizer-heavy tune used when a race to the emergency room or clinic is discussed.
  • The entire premise of some of the episodes, more specifically the episodes where the illness in question have no precursor.
  • Out of all the conditions featured, the rare genetic disorder of metabolism Lesch-Nyhan Syndrome is especially cruel, and frightening. Affected sufferers suffer from chronic muscle weakness, developmental delays... and an overwhelming compulsion to harm themselves, initially through biting, but then by beating oneself to the point of bleeding violently and wavering in and out of consciousness. The child afflicted with the condition in the episode where it is featured goes to the point of biting his own lower lip clean off his face. Even after the vast majority of his deciduous teeth were extracted, the child still had such a compulsion to harm himself that he began repeatedly smashing his head into any hard surface he could find, but his cries of pain showed quite clearly that he didn't want to do this. This child had essentially become a slave to his illness, aware in some capacity of what was happening, but with no ability to stop his self-destructive behaviour.
• Paranoia Fuel: A lot of the diseases featured are caused when the body inexplicably attacks itself out of nowhere. Enough said.
• Squick: And how!
• Tear Jerker: If a child is sick, expect major Tear Jerker potential. A late episode even had a doctor choking up on camera.
  • When some of the illnesses diagnosed are terminal, have no cure, can't be treated, or if they were diagnosed too late.
  • The case of the woman with FOP and she died before the episode premiered.
  • Also applies if the implications of a child's disease is eventual early death, even with treatment. Many parents have emotional reactions if they think their children will get a diagnosis such as cancer or cystic fibrosis. One of the best examples is Harry Crowther, who was doing great at filming, but is assumed to have a short life because of his atypical progeria.