Mystery Diagnosis is a TV docudrama that airs on Discovery Life and TLC showcasing people with rare conditions and diseases that ran from 2005-2011.
Tropes for Mystery Diagnosis
Abusive Parents: Some parents are accused of this because a child's condition involves heavy bruising. One example is a little girl named Julia, who turned out to have a blood disorder called Glansman's Thrombostinia.
Arc Words: Mystery Diagnosis is very fond of these. They include:
For some unknown reason
In healthy individuals [explanation of how a healthy body works.] But in patients like [patient name], [explanation of disease's effects.]
"Nothing short of shocking" is used to describe test results often.
"Nothing could have prepared [X] for what [Y] revealed/what happened next/what they saw", etc.
New symptoms are always described as "emerging" or "stopping [X] dead in their tracks." New symptoms are also often characterized as "frightening," "even more frightening," or "bizarre."
Towards the end of the segment, expect a variation of "But why did it take so long for the doctors to diagnose the condition?". This is almost always worded as He/She/They "can't help but wonder" why the condition took so long to diagnose.
Each episode also has variations of comparisons between patients, because some of them have symptoms too debilitating to ignore, while others' symptoms act like a sleeping giant, and still others have symptoms, but don't do anything about them for a long time.
"Head-to-toe exam" and "thorough head-to-toe exam" are also used a lot.
There will often be a reference to "If you hear hoofbeats, look for horses, not zebras," and an admission that this condition was in fact a zebra.
Adult Fear: The reason the show is rated TV-14. This is especially true of the parents you see on the show with babies or young children. Actually, the whole thing can be rather freaky (see below).
Babies Make Everything Better: Maria Lazazarro, the mother in "The Girl Who Stopped Growing," invokes this trope. She explains that her daughter's being born with mysterious disabilities took a toll on her marriage and that when she and her husband decided to have a second baby, they figured it would fix things. The baby, little Samantha's brother Jake, was born with the same disabilities, later diagnosed as Cockayne Syndrome. The couple divorced after Jake was born.
Big Eater: The patient in the second half of "The Boy Who Couldn't Stop Eating," Connor Heybach, has Prader-Willi Syndrome. It's a condition in which the hypothalamus malfunctions, keeping the person with it from ever feeling full no matter how much or often they eat.
Also occurred with little Haven Fowler in "Trapped Inside their Bodies." One of the main symptoms of her ROHAAD Syndrome is rapid weight gain/obesity and eating great quantities of food in your sleep.
Completely inverted with Samantha Mina, who suffers from SMA Syndrome. This affects one of the arteries in the intestine and makes it impossible to eat without vomiting, cramps, and extreme pain.
In addition, commonly inverted with anyone whose symptoms include significant stomach issues, which often leads to weight loss and total or almost total loss of desire to eat.
Body Horror: To varying degrees depending on the episode you're watching. In some, the worst you'll get is a close-up of a blood draw. In others, you'll see close-ups of horrific rashes, bruising, or in one case, a home video of a boy whose psychological symptoms made him act in "bizarre" ways, such as exhibiting motor and verbal tics at an alarming rate. In the episode focusing on MSU Disease, surveillance footage is shown of the child afflicted with the condition convulsing violently on a hospital bed.
Color-Coded for Your Convenience: A mild and perhaps unintentional example. Patients and their families are usually shown sitting in front of red or yellow backgrounds (usually red for patients, yellow for family). Doctors are always shown with blue backgrounds.
Critical Research Failure: In Universe. Both literally on behalf of incorrect diagnoses, and figuratively in the case of one of the show's catchphrases ("But why did it take so long for the doctors to diagnose the condition?") - Never have any of the diseases featured not been known to science and medicine, but they often masquerade as other conditions, such as the improper deployment of Anti-Yo Antibody damaging the cerebellum, causing Paraneoplastic Cerebellar Degeneration being mistaken for dementia.
Darker and Edgier: Mystery Diagnosis is aired on the Discovery Fit and Health Channel, which is also home to Monsters Inside Me. Like MD, the stories featured on that show usually involve someone falling prey to symptoms which cannot be pinpointed. Unlike MD, the fates of these contributors can be pretty grim. In fact, several sufferers actually died from the parasite they contracted. To make it even worse, those victims are often children.
The channel is also home to Mystery ER, which has the exact same premise as Mystery Diagnosis, except that everything tends to be solved in the ER. Some episodes are Darker and Edgier than MD, including one where a child wasn't traditionally ill; his mom was committing Munchausen by Proxy.
The channel (now Discovery Life) has become home to Diagnose Me. This show could be considered a Darker and Edgier version of Mystery Diagnosis because the narration is largely replaced with reenactments of the actual symptoms and doctor's appointments, some of which can get pretty graphic. Some of the diseases featured are highly graphic as well, including a disease that causes fingernails to grow from the scalp, and one that causes the hormone liptin to cease functioning. This results in a heavily distended stomach, starving hunger, alarming thinness, and huge skin welts.
Doctor Jerk: Some of the doctors on the show act like this, especially the ones who are treating children (notably girls) and tell the parents the kid is just being overly dramatic, when the parent knows something is really wrong or the child is clearly in pain or distress.
Early Installment Weirdness: Quite a bit of it, mostly due to the change of narrators from David Guion to David Scott. Guion's voice is softer and more modulated, but he has some pronunciation issues. In one episode, he drops the "p" in "symptom" and very nearly drops the "m" when talking about a woman named Kim.
The show also originally had three "medical mysteries" of about twenty minutes each. By about the second season, this was dropped in favor of two half-hour stories.
In the earliest episodes, narration was exclusively in past tense ("Kathy took Isaac to the pediatrician" rather than "Kathy takes...") From about season two on, narration was in present tense except in cases where past tense was absolutely needed.
Initially, more common diseases were featured, such as Pulmonary Hypotension, Trigeminal Neuralgia and Emphysema. Eventually, these episodes were phased out in favour of the more rare and mysterious conditions.
Edutainment Show: Of course, nothing is a substitute for actual medical advice, but if you're a big fan, you will learn a lot about rare diseases and symptoms.
Gross-Up Close-Up: Sometimes, particularly if the patient of the day is suffering from a flesh-eating disease (which happened a few times). This can also happen with large amounts of blood, or even diagrams (such as those that show cholesterol building up around a heart).
I Just Want to Be Normal: Lampshaded and played straight. Naturally, contributors' illnesses make them feel this way, and they say it. Many parents fear that mysterious conditions will keep their kids from being "normal" children as well.
Incurable Cough of Death: If an episode involves a respiratory condition, expect plenty of coughing, which can be mistaken for this. Justified in that sometimes, the respiratory symptoms do all but kill the featured patient.
Mama Bear: Some of the moms of young children on the show who, when confronted with doctors who basically tell them to go home and quit stressing over their kids, tell the doctors to shove it and start doing their own research.
Trademark Favorite Food: A variant; it's more of a Symptomatic Favorite Food. Applies to any illness that makes the patient crave certain foods to get the nutrients or ingredients in them. Salt is a common craving-inducer, which usually indicates a kidney problem. One patient in particular, a young child with ADH deficiency, had an intense craving for water due to her condition causing her to drink but never feel quenched. She eventually drank so much water that she dealt incurable damage to her brain from it swelling up.
Two First Names: Patient Kylie Monica and Dr. Carrie Judy (from two separate episodes).
Woobie of the Week: The patients understandably become so distraught over their illnesses, they pretty much have to be this. Especially true in the case of kids.
Your Princess Is in Another Castle: Happened a couple of times, where the actual diagnosis was not a diagnosis itself, but a hallmark of some other disease. Examples included cold agglutinin disease as a hallmark for undiagnosed leukemia and Crohn's symptoms as a cover for a disease called Hermansky-Pudlak syndrome.
Sometimes happens because the guests are diagnosed with some type of common or mild disease. They are given medication that seems to work for awhile or clears up the symptoms completely, but then stops working or doesn't respond to a new symptom. Can also happen in cases where the treatment or side effects related to the real diagnosis are actually more devastating than the disease itself.
Also happens when doctors persistently diagnose or treat what they think is one disease, but turns out to be another. Examples include: