Tear Jerker: The climax of "Goth to Have Friends". Feeling ignored by Budge, Creepie makes friends with the local goth kids, and offers to help meet their favorite band, the Hissing Cockroaches. Unfortunately for them, the Hissing Cockroaches are actual hissing cockroaches. They run off before they could know that, leaving a saddened Creepie alone to be comforted by her bug friends. Fortunately, her and Budge start hanging out again by the end of the episode.
Though Creepie does befriend them again in "Going For Brogue".
Ugly Cute: It's a show with lots and lots of accurately drawn, but personified, bugs. Nearly everything is Ugly Cute.