These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Tearjerker: Gia's death and the lead-up to it is an obvious one, but there are many others. Gia's reaction to Wilhelmina's death, Linda forcing Gia to choose between her and the drugs (made even worse when Gia chooses the drugs), Gia's rape at her drug dealer's hands...
Gia's heartbreakingly innocent reaction to finding out she has AIDS.
Gia: How do I get rid of it?
The Woobie: Both Gia and Linda become this during the course of the movie.