While searching for the Lost City, the Blasterpals are shot down by the evil Dr. Minus, who is trying to take over the galaxy. But as luck would have it, their rocket ship crash-lands right next to the Lost City itself, which might just contain a secret that will stop Dr. Minus' plans.
This game was later remade as Math Blaster: Ages 9-12.
This game provides examples of:
- Cephalothorax: The creatures you make in the Creature Creator are spheres, cones, and cubes with faces and limbs.
- Combining Mecha: The Lost City (really just four buildings) combine into a new ship for the Blasterpals after all of the puzzles are finished.
- Early-Installment Weirdness: Dr. Minus uses the term "Blasternauts" (plural) to refer to the three heroes collectively. Evidently, the term "Blasterpals" hadn't been established yet.
- Large Ham: Dr. Minus has his moments.
- Millennium Bug: Like its predecessor, the game suffers from this— any game played after 2000 will produce a completion certificate with the date given as the corresponding year in the 1900s. As in, if you finished the game in 2001, your certificate would say 1901.
- Mooks: Dr. Minus's forces are comprised of Negatrons, blobby-looking yellow humanoids that appear in the Maze Craze and Positron Splash minigames.
- Pop Up Video Games: Downplayed. When the Lost City combines together, the player is given the option to view the resulting ship's internal systems. Each system animates when viewed.
- Red Right Hand: Dr. Minus has a humanoid-looking left hand while his right hand is a robotic claw. With his legs, it's reversed, with his right leg looking humanoid while the left one looks robotic.
- Retro Rocket: The purple one from In Search of Spot returns... and is promptly shot down. It never appears again for the rest of the series.
- Space Is Noisy: The Blasterpals can hear Dr. Minus's ship catching up with theirs in the opening. Blasternaut initially thinks its Spot revving his jets.
- Video Game 3D Leap: This game creates the Blasterpals with CGI, an upgrade that did not carry over to most subsequent entries. And even here, they revert to 2D when they're inside a Mini-Game.
- Villain: Exit, Stage Left: At the end of the game, Dr. Minus is thwarted, but he escapes to swear vengeance. As with the Trash Alien in the previous game, this never really amounted to anything in subsequent games. The only time Dr. Minus appears after Lost City is a cameo in Mega Math Blaster, in which he is shown in a jail cell.
