* ActorAllusion: Michael-Leon Wooley, the voice of Twayne, once provided the voice for Audry II, the man-eating plant from ''Little Shop Of Horrors'' on Broadway. In the episode ''Little Ship of Horrors'' there is a species of plant people resembling Audrey II running a flower shop. Wooley provided the voice of the shop owner.
* HeyItsThatVoice: Kong is [[Series/ThirtyRock Ken Parcell]].
** Natasha Leggero, the voice of Callie, was a 2010 ''Last Comic Standing'' judge (Leggero was also the replacement voice of Ethyl on Comedy Central's ''Brickleberry''), while Randall's voice actor Kurt Metzger was a contestant (and even won best joke of the season). Both also later ended up on Comedy Central's 2010 Hot List.
** After her sex change in "Mark Loves Dick", Callie's voice changes into [[{{Archer}} H. Jon Benjamin.]]
** At least three ''SaturdayNightLive'' cast members have done voicework on this show: Kate [=McKinnon=] (who appeared on the show before she joined ''SNL''), Bill Hader, and Kristen Wiig.
* NamesTheSame: One of the characters on this show is named Frank Grimes. It's not the same one who was angry at Homer for living a cushy life (despite being a total idiot) and ends up having a VillainousBreakdown and electrocuting himself after Homer enters and wins a nuclear plant design contest for children. Justified as David M. Stern (a former writer and story consultant for ''TheSimpsons'') worked on this show.