* ActorInspiredElement: The part where Susan's dress rips at the club was suggested by Cary Grant. He had got his pants zipper caught in another woman's dress and had to instinctively follow her as a result.
* AFIS100YearsSeries:
** AFIS100Years100Movies: #97
** AFIS100Years100Laughs: #14
** AFIS100Years100Passions: #51
** AFIS100Years100Movies10THAnniversaryEdition: #88
* CreatorBacklash: Howard Hawks says he regretted making everyone in the cast crazy, wishing there had been a straight man or two to keep things grounded. Averted with the two stars though, as they loved working on the film.
* FatalMethodActing: Narrowly averted. Katherine Hepburn was standing right in front of the leopard, wearing a skirt lined with little metal pieces to make it swing prettily. She made a sudden turn and the leopard lunged for her back. Only the trainer's whip saved her.
* MissingTrailerScene: The trailer is actually made up of a lot of unused takes of existing scenes in the movie.
* PlayingAgainstType:
** Cary Grant, known for playing cool and charming guys, plays a mild-mannered, dorky scientist.
** Likewise, Katharine Hepburn, typically cast as a hyper-intelligent, on-the-ball, DefrostingIceQueen sort, as the scatterbrained Susan.
* RealitySubtext: The attitude of the two leads towards the leopard is reflected in their characters. Katherine Hepburn was more fearless around it, while Cary Grant was wary of it - to the point where doubles and stand-ins had to be used in a lot of scenes.
* ScienceMarchesOn: The clavicle in question comes from a brontosaurus, which, even at the time, was recognized by the scientific community as ''Apatosaurus''.
* StarDerailingRole: Briefly for Katherine Hepburn, who was labelled 'Box Office Poison' after this film. She broke her RKO contract after they only offered her a part in a B-movie. But she quickly rebounded with ''Film/ThePhiladelphiaStory''.
* ThoseTwoActors: The second of four movies to star Katherine Hepburn and Cary Grant.
* ThrowItIn: "I just went GAY all of a sudden!" Note the abrupt cut immediately after, indicating that the cast and crew lost it.
* WhatCouldHaveBeen:
** Howard Hawks' 1964 comedy ''Man's Favorite Sport?'' is an intentional {{homage}} to ''Bringing Up Baby'', and Hawks only cast Rock Hudson and Paula Prentiss as the leads in the later film after trying unsuccessfully to coax Cary Grant and Katharine Hepburn into reuniting for the project.
** The original script had some scenes in the middle of the movie where David and Susan declare their love for each other. These were filmed but not included in the final cut of the film.
** The script had an elaborate pie fight but it wasn't filmed.