* ActorAllusion:
** There's quite a few jabs at Creator/WilliamShatner's iconic Captain Kirk role, such as when Denny is given a cellphone by one of his many girlfriends and it makes the ''Franchise/StarTrek'' communicator beeping sound whenever he flips it open.
** Also, when describing a parasitic water bug,
-->'''Alan''': They call them cling-ons.
-->'''Denny''': Did you say ''Klingons''!?
** The third season episode "Son of the Defender" used footage from the 1950's Defender TV movie featuring Shatner to present Denny as a young attorney clashing with his father. It was surprisingly emotional.
** In one episode, Valerie Bertinelli appeared as a guest character, and her appearance was heralded with the theme from ''Series/OneDayAtATime'', the show that made her a star.
* ActorSharedBackground: Denny Crane's larger-than-life persona, and his anxieties about being washed-up. One could argue that Shatner fits that bill and in many ways Denny is a reflection of himself. Especially Denny doing Priceline commercials. David E Kelley mentioned wanting William Shatner for the role precisely because he would fit perfectly and was willing to poke fun at himself.
* FakeAmerican: Canadian Creator/WilliamShatner as staunch, gun-loving Denny Crane.
* IAmNotSpock: For a lot of people, this show was responsible for Creator/WilliamShatner not just being Captain Kirk. In fact inverted, now people make Denny Crane jokes about old ''Series/{{Star Trek|The Original Series}}'' episodes.
* YouMightRememberMeFrom: Creator/CandiceBergen's earlier claim to fame was on the [[LongRunner long-running]] sitcom ''Series/MurphyBrown''.
** And Christian Clemenson played sidekick to Bruce Campbell as another lawyer, Socrates Poole, in ''Series/TheAdventuresOfBriscoCountyJr''.
*** Perhaps more relevantly, Clemenson played Spader's brother in Bad Influence.
*** John Larroquette, who joined the cast as the straight-laced DeadpanSnarker Carl Sack is certainly better known for playing a lawyer, who was the complete opposite on ''Series/NightCourt'', Dan Fielding.