NANA. This troper can't even give specific examples - every single episode left her in tears.
This troper teared up at the scene where Nana and Hachiko go to Trapnest's concert in Hachiko's hometown, and Nana sees Ren for the first time in two years.
It doesn't help that the song Trapnest performed was the extremely touching a little pain, either.
This troper also bawled when Hachiko saw Shouji hugging Sachiko. She (Hachiko) was so shocked that she refused to fight for Shouji, and broke up with him.
Just thinking about this makes this troper feel sad and depressed.
Another tearjerker scene was when Hachiko broke up with Nobu because she got pregnant and decided that Takumi was the better choice since he would be able to support the child without any trouble. She also thought that she was in love with Takumi.
Don't forget when Ren died.
Yasu going with Misato to Nana's hotel to tell her the news. And she was so happy somebody came for her, too.
This troper fought to keep themself from breaking into tears each time the ending song, Kuroi Namida, started playing.