Tear Jerker / Jessica

• When Cameron loses his mother from cancer. Cameron gets so angry by this he accidentally crushes his Yellow Cartridge, killing Jessica.
• Cameron was about to feel better about losing his mother but then his brother ended up dying. Unknown if it was from severe sadness or suicide.
• When Cameron sees Jessica all beaten and torn because he accidentally stepped on her Yellow Cartridge.
• When Jessica gives Cameron her "The Reason You Suck" Speech.

  Jessica: "You kept me close. We were the best of friends. Then you broke me – killed me – and then discarded me. I will never die. I am too close to your heart. I thought you cared. I thought you really cared. Wasn't I special to you, Cameron? Wasn't I your best friend? Yes. We were partners, you and I. We took down Team Rocket together. We conquered Kanto, Johto, and even Red together... I thought you cared, but I was wrong. You let rage get the better of you and snapped me like a twig. You crushed me, as well as my heart. You killed me. You're a murderer, Cameron."

• When the characters tell Cameron of their disappointment in him.

  Belle: Cameron... how could you do such a thing...?

  Cheren: You... I looked up to you... how could you betray me...?

  Alder: This... is unforgivable... but maybe, she will...

  N: You said that you wanted people and Pokémon to live in peace... then why did you...?