This is based on opinion. Please don't list it on a work's trope example list.
Tear Jerker / A Dirty Job
Charlie walking back into the hospital room to find a man in a minty green suit with his wife...who won't respond to him.
Also, by Christopher Moore, A Dirty Job, while hilarious, has the most touching "goodbye" scene between Charlie and his daughter, Sophie, as he dies from wounds suffered in the final battle with the Morrigan after realizing that he is not the new incarnation of Death; Sophie is. One sentence from Sophie is the worst: "Goodbye, Daddy." I couldn't stop crying for two hours. The author is a GENIUS!