!!A
* ''Anime/AceAttorney'': [[Manga/AttackOnTitan Eren Jaegar]] has it rough being a lawyer facing with his rival [[VideoGame/HyruleWarriors Zant]], solving cases with [[Anime/PuellaMagiMadokaMagica Madoka Kaname]] and [[WebComic/AxisPowersHetalia Norway]].
* ''Manga/AiYoriAoshi'': College student [[WesternAnimation/Ben10AlienForce Ben Tennyson]] bumps into childhood friend/[[ChildhoodMarriagePromise arranged bride]] [[VisualNovel/FateStayNight Saber]], become an OfficialCouple (in secret) and move into a mansion consisting of Ben's guardian [[Manga/AzumangaDaioh Yukari Tanizaki]] and tenants/[[TheUnwantedHarem unwanted harems]] [[Manga/InuYasha Kagome Higurashi]], [[Franchise/{{Disgaea}} Laharl]], [[Manga/ShugoChara Kusu Kusu]] and [[Anime/NurseWitchKomugi Komugi Nakahara]].
* ''Manga/AhMyGoddess'': [[Anime/TenchiMuyo Tenchi Masaki]] is an ordinary college student who accidentally gets [[VideoGame/MetalGearSolid3 The Boss]] to be his girlfriend. The Boss's sisters [[VideoGame/SoulCalibur Ivy]] and [[Anime/XMen Storm]] are also major characters.
* ''Manga/{{Akira}}'': [[Manga/YuYuHakusho Yuusuke Urameshi]] becomes insane after being tested on by the government. It's up to his friend [[Anime/TransformersEnergon Ironhide]] and [[Anime/MobileSuitGundamThe08thMSTeam Karen Joshua]] to stop him.
* ''LightNovel/AllisonAndLillia'': TeenGenius [[Anime/AfterWarGundamX Kid Salsamille]] and AcePilot [[Manga/{{Naruto}} Hinata Hyuuga]] go on a year long treasure hunt around the world. It then shifts over fifteen years to the adventures of [[Anime/MagicalGirlLyricalNanoha Fate Testarossa]], Kid and Hinata's daughter and her friend [[Anime/{{Vandread}} Hibiki Tokai]].
* ''VideoGame/{{Amagami}}'': [[Anime/LibraryWar Atsushi Dojo]] just got dumped by [[Manga/HighSchoolOfTheDead Zeke]] on Christmas Eve. He then goes on with his life, while being annoyed by his younger sister [[AgarestSenki Fiona]], and can either romance his sempai [[Anime/TengenToppaGurrenLagann Boota]], his best friend [[SuikodenV Muroon]], his kouhai [[ShugoChara Il]] (while her story was narrated by [[LightNovel/DemonKingDaimao Peterhausen]]), another one of his kouhai [[Manga/BlackCat Rinslet Walker]], his childhood friend [[Manga/HidamariSketch Sae]], the class president [[Anime/NowAndThenHereAndThere Lala-Ru]], or [[spoiler: StalkerWithACrush [[VideoGame/CrossEdge Vivi]]]].
* ''VideoGame/AmnesiaOtome'': [[Anime/CodeGeass Nunnally Lamperouge]] is an [[ExactlyWhatItSaysOnTheTin Amnesiac]] [[AmnesiacHero Heroine]] who falls in love with [[Manga/FairyTale Natsu Dragneel]], [[Manga/AttackOnTitan Jean Kirschtein]], [[Anime/NeonGenesisEvangelion Kaworu Nagisa]], [[Manga/{{Naruto}} Sai]], and [[VisualNovel/DanganRonpa Chihiro Fujisaki]].
* ''Manga/AngelSanctuary'': [[Anime/BlueGender Yuji Kaidou]] wants to [[BrotherSisterIncest fuck his sister]] [[Manga/{{Mahoromatic}} Mahoro Ando]]. [[JustHereForGodzilla Oh and something about being caught in the middle of a war between Heaven and Hell]]....including how [[Manga/AttackOnTitan Eld Jinn]] wants to [[FoeYay fuck Yuji]] for being the [[ReincarnationRomance reincarnation]] of [[IncestIsRelative his sister]] [[Anime/TenchiMuyo Ryoko]].
* ''Anime/AnoHanaTheFlowerWeSawThatDay'': [[LightNovel/OokamiSan Ryoushi Morino]], [[Anime/CodeGeass Suzaku Kururugi]], [[LightNovel/SwordArtOnline Asuna Yuuki]], [[LightNovel/{{Oreimo}} Ayase Aragaki]] and [[Franchise/AceAttorney Phoenix Wright]] reunite after ten years to grant the wish of their deceased friend, [[Manga/SKETDance Roman Saotome]].
* ''Franchise/{{Anpanman}}'': [[Anime/MobileSuitGundam Matilda Ajan]] fights the evil forces of [[Anime/DragonBallZ Frieza and Bulma]].
* ''Manga/ArakawaUnderTheBridge'': [[Anime/MobileSuitGundam00 Tieria Erde]] falls into a river and gets saved by [[Manga/BlackButler Ciel Phantomhive]] and becomes the latter's boyfriend in return. [[VideoGame/TalesOfSymphonia Kratos Aurion]] narrates.
* ''Manga/ArcadeGamerFubuki'': [[Manga/RozenMaiden Hinaichigo]] is a girl that puts on panties to become a pro gamer. And faces off against people like [[Anime/MobileSuitGundam Amuro Ray]], [[Anime/BambooBlade Kirino Chiba]] and even [[Series/KamenRider Rider 1]]
* ''Manga/{{ARIA}}'': ThreeAmigos [[Manga/HanamaruKindergarten Yamamoto]], [[Anime/MagicalGirlLyricalNanoha Subaru]] and [[VisualNovel/{{CLANNAD}} Kyou]] work for a gondolier tour business under their respective mentors [[Manga/XxxHolic Yuko]], [[Anime/CodeGeass Cornelia]] and [[Anime/RevolutionaryGirlUtena Utena]] and would mentoring [[Anime/PuellaMagiMadokaMagica Mami]], [[VisualNovel/{{CLANNAD}} Nagisa]], & [[LightNovel/ThePetGirlOfSakurasou Mashiro]].
* ''Manga/AssassinationClassroom'': Highschoolers who consist among others of [[VideoGame/Persona5 Sadayo Kawakami]], [[VisualNovel/LittleBusters Mio Nishizono]], [[Anime/KillLaKill Mako Mankanshoku]], [[Manga/BlackButler Ran-Mao]], [[Manga/KOn Ritsu Tainaka]], [[Anime/BloodLad Staz Charlie Blood]], and [[Manga/BlueExorcist Rin Okumura]] are asked to kill their teacher [[Manga/BlackButler Grell Sutcliffe]] before the end of their year or else the world is destroyed.
** ''OVA Pilot'': [[Manga/{{Nisekoi}} Chitoge Kirisaki]], [[Manga/{{Oreimo}} Kirino Kosaka]], [[VisualNovel/SuperDanganRonpa2 Sonia Nevermind]], [[Manga/MahouSenseiNegima Negi Springfield]], and others try to kill [[VisualNovel/FateStayNight Gilgamesh]].
* ''LightNovel/TheAsteriskWar'': [[LightNovel/TheIrregularAtMagicHighSchool Mikihiko Yoshida]] gets transferred to a school for magical fighters and earns the affections of [[Anime/MobileSuitGundamIronBloodedOrphans Almiria Bauduin]], [[LightNovel/{{Oreshura}} Mana Natsukawa]], [[Manga/WitchCraftWorks Tanpopo Kuraishi]] and [[Manga/MonthlyGirlsNozakiKun Chiyo Sakura]]. Together, they must win the fighting tournament between schools and discover what happened to Mikihiko's sister [[LightNovel/StrikeTheBlood Nina Adelard]].
* ''LightNovel/AsuraCryin'': [[Anime/YesPrettyCure5 Nuts]] and his childhood ghost friend, [[Manga/SamuraiHaremAsuNoYoichi Ayame]], find out from [[Anime/StrikeWitches Mina]] that they can summon a giant robot thing. At the same time, a fire-throwing demon miko by the name of [[Anime/PaniPoniDash Ichijou]] comes into Nuts' life to help him figure out just what's going on.
* ''Manga/AttackOnTitan'': [[Anime/GuiltyCrown Shu Ouma]] lost his mother, [[Manga/FullmetalAlchemist Trisha Elric]], when man-eating giants broke into the fortress city. He joins [[Anime/TengenToppaGurrenLagann Yoko Littner, Kittan Bachika]], [[VideoGame/FireEmblemAwakening Robin/The Avatar, Lucina]], [[Anime/MobileSuitGundamAGE Millais Alloy]], [[Music/{{Vocaloid}} Miku Hatsune]], [[Anime/{{Tsuritama}} Yuki Sanada]], [[Manga/TheWorldGodOnlyKnows Keima Katsuragi]], [[Manga/YuruYuri Akari Akaza]], [[VisualNovel/UminekoWhenTheyCry Battler Ushiromiya]], [[LightNovel/{{Bakemonogatari}} Koyomi Araragi]] and [[Manga/{{Bleach}} Toshiro Hitsugaya]] to defeat these monsters.
* ''Manga/AxisPowersHetalia'': [[Manga/BlackLagoon Rock]], [[VideoGame/StreetFighterIV Guile]], and [[Anime/YuGiOh Katsuya Jounouchi]] unite to become the Axis Powers. They fight the Allied Powers, led by [[Anime/TengenToppaGurrenLagann Kamina]] who controls [[WesternAnimation/FostersHomeForImaginaryFriends Bloo]], [[Anime/FullmetalAlchemist Gluttony]], [[Manga/{{Trigun}} Vash the Stampede]], and [[Manga/ThePrinceOfTennis Shusuke Fuji]].
** [[Manga/FullmetalAlchemist Alphonse is Edward's]] younger... sister?
** ''[[GenderFlip "I Was Overwhelmed by Heroines"/Nyotalia]]'': Some of the cast becomes [[Manga/{{Parasyte}} Akiho Suzuki]], [[Manga/FullmetalAlchemist May Chang]], [[Manga/SayonaraZetsubouSensei Nami Hito]], [[Anime/HighSchoolFleet Coco-chan]], [[Anime/PuellaMagiMadokaMagica Madoka Kaname]], [[Manga/{{Inuyasha}} Kagome Higurashi]], and [[Franchise/{{Neptunia}} Histoire]].
* ''Manga/AzumangaDaioh'': ChildProdigy [[Manga/{{Bleach}} Nel Tu]] goes to school and befriends {{Jerkass}} [[VisualNovel/ToHeart Shiho Nagaoka]], StraightMan [[WesternAnimation/AdventureTime Princess Bubblegum]], [[Manga/LoveHina Motoko Aoyama]], CloudCuckooLander [[LightNovel/HaruhiSuzumiya Tsuruya]] and [[YouGoGirl athletic]] [[Anime/MobileSuitGundamSeedDestiny Stella Lousier]]. They belong to [[Manga/YoureUnderArrest Miyuki Kobayakawa's]] class. Also features a possibly-hallucinatory [[Anime/{{Gunbuster}} Coach Ohta]] who is a bird.
** ''Azumanga Web Daioh'': The girls are [[Manga/OuranHighSchoolHostClub Honey]], [[VideoGame/{{Disgaea}} Etna]], [[VisualNovel/HigurashiWhenTheyCry Mion Sonozaki]], [[VisualNovel/FateStayNight Saber]], and [[Manga/{{Hellsing}} Heinkel Wolfe]]. Miyuki is [[Manga/SailorMoon Sailor Mercury]] in the other series.

!!B
* ''LightNovel/{{Baccano}}'': [[Anime/SailorMoon Jadeite]], [[Anime/SonicX Cream The Rabbit]], [[Anime/PantyAndStockingWithGarterbelt Brief]], [[Anime/TheBigO Roger Smith]] and [[LoadsAndLoadsOfCharacters slew of others]] get in a slew of problems in prohibition-era America.
* ''LightNovel/BakaAndTestSummonTheBeasts'': Class F Idiot [[Manga/TheWorldGodOnlyKnows Keima Katsuragi]] and his fellow students [[VideoGame/SenranKagura Asuka]], [[Anime/PuellaMagiMadokaMagica Mami Tomoe]], [[Anime/{{Free}} Makoto Tachibana]], [[Manga/BlackButler Mey-Rin]], and [[VisualNovel/DanganRonpa Chihiro Fujisaki]] try to defeat Class A students [[VideoGame/BlazBlue Makoto Nanaya]], [[Manga/LuckyStar Kagami Hiiragi]], among others in test score based battles in an academy run by Disciplinary Master [[Franchise/MetalGear Solid Snake]].
* ''LightNovel/{{Bakemonogatari}}'': [[Manga/SayonaraZetsubouSensei Nozomu Itoshiki]] finds himself helping [[Manga/{{ARIA}} Aika]] deal with a spirit problem by going to [[LightNovel/TheFamiliarOfZero Guiche]] for help. He ends up helping [[Manga/{{NEEDLESS}} Disc]], [[Series/KamenRiderDecade Kivaara]], [[LightNovel/KyouranKazokuNikki Yuka]] and [[Manga/{{Saki}} Mihoko]] as well. All while having to deal with his sisters, [[Manga/KamenNoMaidGuy Naeka]] and [[VisualNovel/ChaosHead Rimi]] at home.
* ''Anime/{{Bakugan}}'': [[TransformersAnimated Grimlock]] enters the human world to keep [[Anime/MobileSuitGundam00 Ian Vashti]] from destroying Vestroia. In order to do so, he has to work with [[Manga/MariaHolic Mariya Shido]] and her friends [[Anime/PumpkinScissors Marchis]], [[LightNovel/ChromeShelledRegios Mifi Lotten]], [[Manga/InuYasha Rin]], Anime/LeChevalierDEon & [[Anime/SonicX Tails]] and fight [[Manga/TenjhoTenge Souichirou Nagi]] [[spoiler:(Who's really Rin)]] & [[Anime/{{Dancougar}} General Gil Dorom]]; [[Manga/HayateTheCombatButler Wataru Tachibana]], [[Anime/{{Basquash}} Naviga Stelte]] & [[Anime/StrikeWitches Perrine-H. Clostermann]] start out as villains, but eventually make a FaceHeelTurn.
* ''Manga/{{Bakuman}}'': [[LightNovel/ACertainMagicalIndex Touma Kamijou]] decides to work as a manga artist with [[Manga/{{Naruto}} Sai]] in order to impress his friend [[Manga/HeavensLostProperty Ikaros]].
* ''Manga/BambooBlade'': Down on luck Kendo instructor [[Anime/MacrossFrontier Ozma Lee]] assembles a team of female Kendo students including [[VisualNovel/{{CLANNAD}} Tomoyo Sakagami]], [[Anime/TweenyWitches Arusu]], [[Anime/KaleidoStar Sora Naegino]], [[Manga/MahouSenseiNegima Negi Springfield]] and [[Manga/{{Chobits}} Yumi Omura]].
* ''[[Anime/GoLion Beast King GoLion]]'': [[Manga/{{Naruto}} Kakashi]], [[Manga/DragonBallZ Frieza]] [[spoiler: before he was KilledOffForReal]],[[Manga/GeGeGeNoKitaro Kitaro]], [[Manga/CrayonShinChan Action Mask]], [[WesternAnimation/{{Animaniacs}} Wakko Warner]], and [[Anime/MobileSuitGundam Fran Bow]] defend their planet from the forces of [[WesternAnimation/BatmanTheAnimatedSeries The Penguin]] and [[Manga/DetectiveConan Kogoro Mouri]].
* ''Anime/BeastWarsII'': [[Anime/ArmoredTrooperVotoms Chirico Cuvie]] and his team fight the evil forces of [[Anime/YuGiOh Gouzaburou Kaiba]], [[Manga/AxisPowersHetalia Japan]] & [[Anime/{{Bakugan}} Helios]] (and their lackeys). [[Manga/AzumangaDaioh Tomo Atoda]] and [[VideoGame/{{Medabots}} Metabee]] watch from outer space.
* ''Manga/{{Beelzebub}}'': Young delinquent [[WesternAnimation/CatDog Cat]] is forced to become the surrogate father of AntiAntichrist [[Anime/BlackRockShooter Dead Master]].
* ''Manga/{{Berserk}}'': [[VideoGame/SonicTheHedgehog Knuckles the Echidna]] is pissed about what [[{{Anime/Inuyasha}} Naraku]] did to him and [[Franchise/StreetFighter Chun-Li]] in the past
** ''Berserk: The Golden Age Arc'' onward: [[Franchise/KamenRider Kamen Rider Birth]] is pissed about what [[Manga/BlackButler Claude Faustus]] did to him and [[VideoGame/{{Skullgirls}} Cerebella]].
* ''Anime/TheBigO'': [[Manga/FruitsBasket Ayame Sohma]] is a skilled negotiator who's often accompanied by his RobotBuddy [[Anime/MobileSuitGundamWing Relena Darlian]]. He frequently runs afoul of [[Anime/SailorMoon Makoto Kino]].
* ''Manga/BirdyTheMighty'':
** OVA Series: SpacePolice officer [[Anime/SailorMoon Usagi Tsukino]] accidentally kills [[Anime/NeonGenesisEvangelion Kensuke Aida]] while chasing after an intergalactic criminal, and winds up SharingABody with Kensuke until she can shut down their syndicate, ran by [[Anime/MacrossPlus Sharon Apple]]. [[VideoGame/MetalGearSolid Solid Snake]], another member of the syndicate, at one point breaks Usagi's arm, [[Anime/CodeGeass C.C.]] is interested in Kensuke, and [[Anime/ShamanicPrincess Apolline Faria]] is Kensuke's sister.
** ''Decode'': Same premise and the crime syndicate's still ran by Sharon (though she's not seen as much this time), but the SpacePolice officer is [[Manga/RosarioToVampire Ruby Tojo]] and she has an IdolSinger disguise, the kid she accidentaly kills is [[Anime/SpiritedAway Haku]], it's [[Anime/CowboyBebop Jet Black]] who breaks Ruby's arm, [[Anime/QueensBlade Nowa]] is Haku's sister, [[Manga/ShugoChara Amu]] is just friends with Haku, and [[Manga/{{Hellsing}} Rip Van Winkle]] is Haku's love interest. Additionally, [[VideoGame/LollipopChainsaw Nick Carlyle]] is a TV producer with [[TheSocialDarwinist Social Darwinist]] tendencies. In the second season, it's revealed that Ruby was friends with [[Manga/DeathNote Teru Mikami]] and Teru's taking care of [[Anime/OutlawStar Melfina]].
* ''Manga/BlackButler'': [[LightNovel/{{Durarara}} Shizuo Heiwajima]] is simply one hell of a butler for [[Manga/OuranHighSchoolHostClub Haruhi Fujioka]], who is an orphan engaged to marry [[Anime/KillLaKill Nui Harime]]. Other staff for Lyuze include [[Manga/BlueExorcist Konekomaru Miwa]], [[VideoGame/AssassinsCreed Desmond Miles]], and [[Manga/SoulEater Blair]]. [[Anime/CodeGeass Lelouch]] is Shizuo's StalkerWithACrush
** In the second season, [[Manga/{{Naruto}} Hinata Hyuga]] and [[Manga/TokyoGhoul Uta]] are their rivals.
** In the drama CD, Shizuo and Haruhi [[TheOtherDarrin were]] [[VideoGame/FinalFantasyVII Sephiroth]] and [[Manga/RozenMaiden Shinku]].
* ''Manga/BlackLagoon'': [[Manga/AxisPowersHetalia Italy]], [[Anime/{{Pokemon}} Dawn]], [[Manga/OnePiece Sanji]], and [[Anime/{{Monster}} Inspector Runge]] form an unlikely team against gangs of terrorists and Neo-Nazis. [[Manga/DragonBall Lunch]] is a Russian mafiya boss who occasionally hires them.
** At one point, they face off against CreepyTwins [[Anime/CodeGeass Euphemia]] and [[Manga/AzumangaDaioh Chiyo]].
* ''Anime/BlackRockShooter'' (OVA): [[LightNovel/{{Bakemonogatari}} Nadeko Sengoku]] must travel to another world to rescue her best friend [[LightNovel/{{Durarara}} Celty Sturluson]]. Meanwhile, Sengoku's other friend, [[Manga/MahouSenseiNegima Ku Fei]] [[MindScrew may or may not]] be involved in the other world.
* ''[[Anime/BloodC Blood-C]]'': [[Manga/FullmetalAlchemist Lan Fan]] is a {{miko}} who battles vampire-like creatures.
* ''Anime/BloodPlus'': After being saved by [[Anime/TengenToppaGurrenLagann Kamina]], [[LightNovel/{{Toradora}} Ami Kawashima]] discovers that she has vampire-like powers and, with the help of her best friend [[Manga/{{Kekkaishi}} Yoshimori]], she must fight her EvilTwin, [[Anime/MobileSuitGundamWing Relena Peacecraft]].
* ''LightNovel/BludgeoningAngelDokurochan'': [[Anime/StrikeWitches Mio Sakamoto]] repeatedly turns [[VideoGame/SoulSeries Cassandra Alexandra]] into a bloody mess and then resurrects [[CrossDressingVoices him]] for laughs. [[LightNovel/{{Toradora}} Taiga Aisaka]] wants to end Cassandra's suffering but she continually fails at that.
* ''Manga/BlueExorcist'': [[LightNovel/ACertainMagicalIndex Accelerator]] learns he and his genius brother [[Anime/CodeGeass Lelouch]] are the sons of Satan, which unintentionally causes their surrogate father [[Manga/FullmetalAlchemist Maes Hughes]] to die. He goes to a school run by [[LightNovel/{{Durarara}} Izaya]] to learn how to become an exorcist.
* ''Manga/BoboboboBobobo'': [[Anime/SoulEater Excalibur]], [[Manga/SayonaraZetsubouSensei Kafuka Fuura]], [[Manga/AxisPowersHetalia France]], [[Anime/MobileSuitGundamSeed Cagalli Yula Attha]], [[Anime/YuGiOh Seto Kaiba]], and [[Manga/AzumangaDaioh Chiyo Mihama]] all fight an evil empire.
* ''Manga/Brave10'': [[VideoGame/FinalFantasyXIII Snow Villiers]] is constantly being pestered to protect by shrine maiden [[VideoGame/DaemonBride Yui Emelia Mitsukihara]], which culminates him staying along with the famous general [[VideoGame/StreetFighterAlpha Charlie Nash]] who employs 'ninja/assassins' like [[VideoGame/BlazBlue Jin Kisaragi]] and [[VisualNovel/FateStayNight Rider]] (Snow's childhood friend) and recruiting some more, all while dealing those who wants to capture Yui Emelia, which includes ninja [[VideoGame/FinalFantasyVII Cloud Strife]] and one-eyed general [[Anime/TekkamanBlade Tekkaman Evil]]
* ''LightNovel/BrothersConflict'': After her father remarries, [[Anime/ACertainScientificRailgun Mikoto Misaka]] is given the option to [[BrotherSisterIncest screw]] one of thirteen brothers including: [[Manga/JoJosBizarreAdventure Jonathan Joestar]], [[Anime/{{Free}} Rei Ryugazaki]], [[Manga/BlackButler Undertaker]], [[Anime/BlueExorcist Rin Okumura]], [[Anime/OuranHighSchoolHostClub Hikaru Hitachiin]], [[VideoGame/DanganRonpa Kiyotaka Ishimaru]], [[Anime/DeathParade Decim]], [[WebComic/AxisPowersHetalia Lithuania]], [[LightNovel/{{Durarara}} Shizuo Heiwajima]], [[VisualNovel/FateZero Waver Velvet]], [[Anime/DigimonAdventureTri Yamato Ishida]], [[Anime/YuGiOhGX Jaden Yuki]], and [[VisualNovel/DiabolikLovers Kanato Sakamaki]]. Mikoto has a WeaselMascot in the form of [[Anime/SayonaraZetsubouSensei Nozomu Itoshiki]].
* ''Anime/BubblegumCrisis'':
** OVA: [[Manga/{{Hellsing}} Integra Hellsing]], [[Manga/BlackLagoon Roberta]], [[Manga/SgtFrog Aki Hinata]], and a signer are a team of superheroines that must deal with robots that go rogue. [[Manga/DeathNote Mello]] is Integra's brother.
** ''Tokyo 2040'': Same premise, only Integra is [[LightNovel/FullMetalPanic Kaname Chidori]], Roberta is [[Anime/DigimonAdventure02 Miyako Inoue]], Aki is [[VideoGame/{{Darkstalkers}} Lilith Aensland]], the signer is [[Anime/{{Vandread}} Jura Basil Elden]], and Mello is [[Manga/{{Bokurano}} Kunihiko Moji]].
* ''Manga/BusouRenkin'': After being killed by a homunculus, [[Anime/CodeGeass Lelouch Lamperouge]] is revived by a strange heart implant that doubles as [[BladeOnAStick his signature weapon]]. His partner-in-action, [[Manga/{{Naruto}} Ino Yamanaka]], fights against the homunculi with a series of blades hidden beneath her school uniform.

!!C
* ''Anime/{{Canaan}}'': Beginning professional photographer [[LightNovel/BakaAndTestSummonTheBeasts Aiko Kudo]] travels to Shanghai to meet [[Anime/AngelBeats Asami Iwasawa]], a girl who saved Aiko before. [[Anime/SoulEater Crona]] targets her, causing Asami to rescue her again. Every now and again, [[Manga/SgtFrog Giroro]] shows up as a Taxi driver.
* ''Anime/CardCaptorSakura'': When her father [[Franchise/MetalGear Otacon]] brings home a book from the university he teaches at, [[VideoGame/FateExtra Saber]] accidentally releases the seal on the book's cover and sends the magic cards inside scattering to the winds. [[Manga/SailorMoon Sailor Mercury]], the guardian beast of the cards, tasks her with their recovery, bestowing unto her a magic staff and the ability to manipulate the cards' power. Now, alongside her best friend [[Anime/PerfectBlue Mima Kirigoe]], she tracks down the cards, often butting heads with her rival [[WesternAnimation/MyLittlePonyFriendshipIsMagic Spike]] and his childhood friend/cousin [[Anime/CodeGeass CC]] all while trying to keep this new life of hers a secret from her family (consisting of her father, and her brother [[VideoGame/Persona4 Kanji]]) and her crush [[Anime/NeonGenesisEvangelion Shinji Ikari]]. In time, she even meets the magician who created the cards, [[Series/PrisonBreak Brad Bellick]] [[spoiler: Including his reincarnation [[Anime/{{Monster}} Johan Liebert]]]].
* ''LightNovel/CatPlanetCuties'': [[Anime/BattleSpiritsShonenToppaBashin Toppa Bashin]] discovers CatGirl [[Anime/BirdyTheMighty Natsumi Hayamiya]] at his Grandfather's funeral. Military based hi-jinks with [[Manga/ToLoveRu Lala Satalin Deviluke]] and [[Anime/{{Blassreiter}} Elea]] and ([[JustifiedTrope somewhat justified]]) cat girl harem ensure.
* ''VisualNovel/{{CLANNAD}}'': [[Anime/MobileSuitGundam00 Graham Aker]] has a change encounter with [[VisualNovel/HigurashiWhenTheyCry Rena Ryuuguu]], who is interested in reviving her school's drama club. Graham's buddy [[LightNovel/{{Baccano}} Jacuzzi Splot]] gets [[ButtMonkey beaten up a lot]].
* ''Manga/{{Chobits}}'': [[LightNovel/HaruhiSuzumiya Kyon]] discovers [[Anime/MobileSuitGundamSEED Lacus Clyne]] in the trash, and eventually begins to develop feelings for him.
* ''VideoGame/ChousokuHenkeiGyrozetter'': [[WesternAnimation/TransformersPrime Shockwave]] recruits [[Anime/RioRainbowGate Rio Rollins]], [[Anime/{{Heroman}} Nick]], [[Anime/NobunagaTheFool Magellan]], [[LightNovel/ACertainMagicalIndex Index]] and [[Anime/YuGiOhArcV Masumi Kotsu]] to fight the evil forces of [[Anime/TransformersCybertron Starscream]] and his henchmen [[Anime/GundamBuildFighters Nils Nielsen]] and [[Music/{{Vocaloid}} Hatsune Miku]]. [[Film/ThreeHundred Leonidas]] and [[Anime/BurstAngel Sei]] also turn up to help the heroes.
* ''Anime/CodeGeass'': [[Manga/XxxHoLic Watanuki]] teams up with mysterious waif [[Anime/CardcaptorSakura Meiling]] to form a guerrilla army so they can make the world a better place for [[Anime/EurekaSeven Eureka]]. Along the way they team up with [[SchoolRumble Tenma]]. However, [[Manga/AzumangaDaioh Chiyo's Dad]] has other plans.
* ''Anime/CowboyBebop'': [[Anime/RanmaOneHalf Ryoga Hibiki]], [[Anime/{{Pokemon}} Professor Oak]], [[Anime/NeonGenesisEvangelion Rei Ayanami]], and [[Anime/DigimonTamers Terriemon]] are bounty hunters who try to make a living while avoiding Ryoga's greatest enemy: '''[[Anime/CodeGeass EMPEROR CHARLES ZI BRITANNIA]]'''.
* ''Anime/CrayonShinChan'': [[Manga/SayonaraZetsubouSensei Majiru Itoshiki]] lives with his parents [[Anime/BlueExorcist Father Fujimoto]] ([[TheOtherDarrin later]] [[{{Manga/Berserk}} Griffith]]) and [[WesternAnimation/SupermanTheAnimatedSeries Livewire]] , baby sister [[{{VisualNovel/Clannad}} Ushio]], and dog [[WesternAnimation/TheSimpsons Ralph Wiggum]]. Majiru goes to school with [[Manga/OsomatsuKun Karamatsu]], [[Anime/FistOfTheNorthStar Ba(r)t]], [[Anime/YoKaiWatch Kanchi Imada]], and [[VisualNovel/FateStayNight Saber]].
* ''Manga/CromartieHighSchool'': [[VideoGame/FinalFantasyVII Cloud Strife]], [[WebComic/OnePunchMan Fukegao]], [[Anime/KillLaKill Ira Gamagoori]], and [[Anime/CowboyBebop Vicious]] ([[BlatantLies who is totally not a robot]]) are a [[JapaneseDelinquents gang of delinquents]] attending the [[WorldOfBadass world's toughest]] [[WorldOfHam high school]].
* ''Anime/CuteHighEarthDefenseClubLove'': [[Manga/{{Nichijou}} Tsuyoshi Nakanojo]], [[Anime/MobileSuitGundamIronBloodedOrphans Eugene Sevenstark]], [[Anime/{{Free}} Toru Iwashimizu]], [[Anime/DanganRonpa3 Soshun Murasame]], and [[WebComic/OnePunchMan Charanko]] are drafted by [[Anime/NeonGenesisEvangelion Keel Lorenz]] to defend the earth against [[WebComic/AxisPowersHetalia Germany]]'s group consisting of [[Manga/SayonaraZetsubouSensei Nozomu Itoshiki]], [[Anime/CodeGeass Lelouch]], and [[Manga/BlackButler Snake]].

!!D
* ''Daisuki! Franchise/HelloKitty'': A day in the life of [[Anime/NeonGenesisEvangelion Rei Ayanami]].
* ''VisualNovel/DanganRonpa The Animation'': [[Anime/NeonGenesisEvangelion Shinji Ikari]], [[VideoGame/TalesOfVesperia Yuri Lowell]], [[VideoGame/TalesOfXillia Milla Maxwell]], [[VideoGame/KidIcarusUprising Viridi]], [[Anime/CodeGeass Suzaku Kururugi]], [[VideoGame/{{Persona 4}} Teddie]], [[Anime/PuellaMagiMadokaMagica Homura Akemi]], [[Anime/{{Bleach}} Hanataro Yamada]], [[Anime/SenkiZesshouSymphogear Maria Cadenzavna Eve]], [[Anime/SuitePrettyCure Ellen Kurokawa]], [[VideoGame/SengokuBasara Date Masamune]], [[Manga/{{Naruto}} Orochimaru]], [[VideoGame/BlazBlue Amane Nishiki]], [[Manga/DeathNote Teru Mikami]] and [[Manga/MagicKnightRayearth Hikaru Shidou]] are all in a GildedCage school where the only way to escape is to kill someone without being found out. The school's headmaster? Anime/{{Doraemon}}.
** ''Anime/DanganRonpa3'': [[Manga/DetectiveConan Conan Edogawa]] along with other survivors of the past games (including [[LightNovel/{{Bakemonogatari}} Nadeko Sengoku]]) are forced to participate in one last killing game headed by Doraemon (who has now turned into [[Manga/ChibiMarukoChan Maruko]]). Some of the other participants include [[Manga/{{Naruto}} The Third Hokage]], [[Manga/{{Berserk}} Griffith]], [[Manga/FullmetalAlchemist Maes Hughes]], [[Music/{{Vocaloid}} Hatsune Miku]], [[VisualNovel/{{Clannad}} Nagisa Furukawa]], [[Manga/BlackButler The Undertaker]], [[Manga/SchoolLive Yuki Takeya]], [[Anime/PokemonOrigins Blue]], [[Manga/TokyoGhoul Juzo Suzuya]], and [[Manga/JoJosBizarreAdventure Mohammed Avdol]]. This time the mastermind is [[spoiler: [[Manga/LuckyStar Konata Izumi]]]]
* ''LightNovel/DateALive'': [[Anime/ActiveRaid Takeru Kuroki]] is an OrdinaryHighSchoolStudent whose sister [[LightNovel/SwordArtOnline Suguha Kirigaya]] tasks him to date Spirits [[LightNovel/InfiniteStratos Laura Bodewig]], [[VideoGame/BlazBlue Celica A. Mercury]], [[Manga/MariaHolic Kanako Miyamae]], [[Manga/TenjouTenge Aya Natsume]], twins [[LightNovel/GonnaBeTheTwinTail Twoearle]] and [[LightNovel/{{Haruchika}} Chika Homura]], to name a few. [[Manga/{{Nichijou}} Mai Minakami]] has sworn to destroy all Sprits, which makes things complicated because she is in love with Takeru as well. In TheMovie, [[LightNovel/TheIrregularAtMagicHighSchool Honoka Mitsui]] appears as a new Spirit.
* ''Anime/DeadLeaves'': Anime/InuYasha and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Princess Luna]] find themselves in a prison, staffed by [[WesternAnimation/TransformersPrime Wheeljack]] and [[Anime/ZatchBell Baltro]].
* ''Manga/DeathNote'': [[Anime/SoulEater Death the Kid]] finds a mystical artifact that causes people to die if their name is written in it. [[Manga/OnePiece Usopp]], the world's greatest detective, tries to stop him. [[spoiler: After Usopp dies, [[Manga/RanmaOneHalf Akane Tendo]] and [[Series/BuffyTheVampireSlayer Oz]] take his place.]]
* ''Anime/DeltoraQuest'': [[Anime/BattleSpiritsShonenToppaBashin Kakeru Nohara]] is joined by swordsman [[Manga/DoctorSlump Senbei Norimaki]] and wild girl [[{{LightNovel/Durarara}} Erika Karisawa]] on a quest to free the land from [[TransformersAnimated Ultra Magnus]].
* ''Anime/DemashitaPowerpuffGirlsZ'': [[Manga/BlackButler Mey-Rin]], [[Anime/OjamajoDoremi Momoko Asuka]], and [[VisualNovel/{{Clannad}} Botan]] are three ordinary girls that are accidentally given super powers by Professor [[VideoGame/FinalFantasyVII Rude]]. Together they have to fight similarly powered villains like [[Anime/FullmetalAlchemist Hohenheim]], [[Manga/DragonBallZ Frieza]], [[WesternAnimation/CliffordTheBigRedDog Emily Elizabeth]], and [[VideoGame/{{Xenosaga}} M.O.M.O.]]. The town's mayor is [[Franchise/MetalGear Otacon]] and VideoGame/{{Kirby}} is Rude's son.
* ''Manga/DetectiveConan'': [[Anime/MobileFighterGGundam Sai Saici]] is a well-known teenaged detective until [[Anime/DragonBallZ Dodoria]] and his partner [[Anime/NeonGenesisEvangelion Gendo Ikari]] drug him and becomes [[Anime/KikisDeliveryService Kiki]]. She's then taken in by [[Anime/ShinkonGattaiGodannar Shukyuu]] & [[Manga/FistOfTheNorthStar Kenshiro]] and is also joined by [[Anime/CowboyBebop Faye Valentine]] (who also shrunk), [[Anime/RanmaOneHalf Genma Saotome]], [[{{LightNovel/Slayers}} Garv]], officer [[Manga/OnePiece Bellamy]] and [[LoadsAndLoadsOfCharacters many others]].
* ''Manga/TheDevilIsAPartTimer'': [[Anime/BloodLad Staz Charlie Blood]], the Devil, falls through a portal into Japan, accompanied by his faithful aide, [[Manga/JoJosBizarreAdventure Josuke Higashikata]]. However, his sworn enemy [[Franchise/DanganRonpa Kyoko Kirigiri]] tracks him down. He ends up doing battle with uber-slacker [[Manga/TheWorldGodOnlyKnows Keima Katsuragi]] and pervert [[Anime/BenTo Hiroaki Uchimoto]]. Also, [[Manga/{{Nisekoi}} Chitoge Kirisaki]] has a ''really'' big crush on him.
* ''AudioPlay/DiabolikLovers'': [[VideoGame/TheIdolmaster Fuka Toyokawa]] is held hostage-[[FreudianSlip I mean]] falls in love with a group of vampire brothers consisting of [[Manga/HaventYouHeardImSakamoto Sakamoto]], [[Manga/BlackButler Finnian]], [[LightNovel/BrothersConflict Ukyo Asahina]], [[Anime/SailorMoonCrystal Nephrite]], [[Manga/{{Beelzebub}} Tatsumi Oga]], and [[Manga/BlackCat Train Heartnet]].
** ''More Blood'': [[Manga/{{Naruto}} Sasori]],[[Manga/SilverSpoon Yugo Hachiken]],[[Anime/{{Free}} Makoto Tachibana]], and [[LightNovel/{{Durarara}} Kasuka Heiwajima]] join in. [[Manga/{{Berserk}} Griffith]] and [[VideoGame/Persona4 Yosuke Hanamura]] are also there.
* ''Anime/DigimonAdventure'': [[VideoGame/DragonQuest Dai]], [[Anime/CromartieHighSchool Noboru Yamaguchi]], [[Anime/TenchiMuyo Mihoshi]], [[WesternAnimation/EdEddAndEddy Marie Kanker]], [[Anime/AhMyGoddess Keiichi Morisato]], [[VideoGame/Persona3 Chihiro Fushimi]], and [[VideoGame/GuiltyGear Bridget]] all land in a digital world, each gaining their own companion. They face off against the likes of [[Manga/OnePiece Sir Crocodile]] and [[VideoGame/SonicTheHedgehog Eggman]]. [[Manga/SailorMoon Chibi-Usa]] later joins them.
** ''Digimon Adventure 2'': Chibi-Usa is back, this time with her old friend Bridget, who has matured into [[WesternAnimation/SouthPark Terrence]]. Together with [[WesternAnimation/TheBoondocks Huey Freeman]], [[Anime/{{Pokemon}} Flannery]], and [[Manga/DragonBall Uub]], later joined by [[Manga/FullmetalAlchemist Edward Elric]], they fight to yet again save the digital world. A major antagonist is [[VideoGame/DotHack Balmung]], and the final bad guy ultimately ends up being an old friend of Uub's father, [[VideoGame/FinalFantasyVII Sephiroth]].
*** ''Anime/DigimonAdventureTri''The gang from the first series is back, now having matured into [[Manga/TokyoGhoul Ken Kaneki]], [[VideoGame/FireEmblemAwakening Robin]], [[Franchise/LoveLive Umi Sonoda]], [[Anime/{{Jormungand}} Jonah]], [[Anime/KatekyoHitmanReborn Haru Miura]], [[Anime/MajesticPrince Ataru Suruga]], [[Anime/SpacePatrolLuluco Alpha Omega Nova]], and [[VideoGame/HyperdimensionNeptunia Dreamcast]].
** ''Anime/DigimonTamers'': [[WesternAnimation/ChalkZone Rudy Tabootie]], [[VideoGame/StreetFighterIV Chun Li]], and [[Anime/FullMetalAlchemist Envy]] are paired with [[Disney/SleepingBeauty Merryweather]], [[Manga/FruitsBasket Arisa Uotani]], and [[Anime/CowboyBebop Ed]].
** ''Anime/DigimonFrontier'': [[Anime/YuGiOh Mokuba Kaiba]], [[Manga/InuYasha Shippo]], [[VisualNovel/FateStayNight Shinji Matou]], [[WesternAnimation/SupermanTheAnimatedSeries the Toyman]], and [[Anime/OjamajoDoremi Caitlin]] arrive in the Digimon world and can take on different forms.
* ''LightNovel/DirtyPair'': [[Anime/TransformersVictory Holi]] and [[Manga/RanmaOneHalf Kodachi Kuno]] who accompanied by their pet [[Anime/BravePoliceJDecker Gunmax]], are a pair of detectives whom leave a trail of (mostly accidental) destruction in their wake.
* ''Manga/DoctorSlump'': [[Manga/FullmetalAlchemist Armstrong]] invents [[Manga/BlackLagoon Balalinka]], a [[RobotGirl robotic]] GenkiGirl.
** In the 90's remake Armstrong and Balalinka are [[Manga/DragonBallZ Lord Slug]] and [[VideoGame/SonicTheHedgehog Amy Rose]].
* ''Anime/{{Doraemon}}'': ''(1973 Version)'' In the future, an unhappy [[Anime/KimbaTheWhiteLion Kimba]] creates a robotic cat named [[Film/TheSmurfs Papa Smurf]] (which later becomes [[Manga/DragonBall Son Goku]]) to be sent back to time and use its tools so the younger Kimba can impress his grade school crush [[WesternAnimation/SnoopyComeHome Frieda]]. He also have to deal with his tormentor [[Manga/OsomatsuKun Iyami]] and their friend [[Disney/TheJungleBook Kaa]].
** ''1979 Version'': In the future, an unhappy [[Franchise/TheMuppets Gonzo]] creates a robotic cat named [[Manga/SazaeSan Katsuo Isono]] to be sent back to time and use its tools so his younger self, [[Anime/{{Yatterman}} Doronjo]], can impress his grade school crush [[Anime/SpeedRacer Trixie]] and change his future. He also have to deal with his tormentor [[Anime/NyanKoi Chatora]] and their friend [[Disney/{{Pinocchio}} Jiminy Cricket]]. Katsuo has a younger sister in [[Anime/CastleInTheSky Sheeta]] and Chatora's is [[Anime/{{Pokemon}} Max]]
** ''2005 Version'': In the future, an unhappy [[VideoGame/FinalFantasyVII Rufus Shinra]] (alternatively, [[VideoGame/Persona3 Shuji Ikutsuki]]) creates a robotic cat named [[WesternAnimation/InvaderZim GIR]] to be sent back to time and use its tools so his younger self can impress his grade school crush [[Anime/BakaAndTest Yoko Takahashi]] and change his future. He also have to deal with his tormentor [[Manga/AssassinationClassroom Ryoma Terasaka]] and their friend [[Anime/NeonGenesisEvangelion Toji Suzuhara]]. Rufus's parents are Manga/SailorMoon and [[WesternAnimation/{{Reboot}} Guardian Bob]].
* ''Manga/DragonBall'': [[Anime/DigimonTamers Guilmon]] meets [[Manga/{{Trigun}} Meryl Stryfe]] who ropes him into a search for the Dragon Balls so she can wish for the perfect man, however in order to gather all seven they must contend with the shape-shifting pig [[Anime/KirbyOfTheStars Dr. Escargon]], desert bandits [[Anime/MobileSuitGundam Amuro Ray]] and [[Anime/HareGuu Guu]] and most notably, [[Manga/OnePiece Buggy the Clown]] and his bumbling minions [[Manga/GingaNagareboshiGin Gin]] and [[Manga/DoctorSlump Suppaman]]. After summoning the Dragon [[Manga/FullmetalAlchemist Alex Louis Armstrong]], Guilmon heads out on his own to train under [[Manga/MagicKnightRayearth Chang Ang]] alongside [[Manga/YuYuHakusho Koenma]].
** ''Anime/DragonBallKai'': After alien invaders, [[VideoGame/SuperSmashBros Captain Falcon]] and [[Manga/OnePiece Mr. 1]] kill several of Guilmon's allies, the remaining heroes must venture into space to gather the Namekian Dragon Balls. Unfortunately, they are unaware that someone else is after these mystical artifacts, the most fearsome dictator in the galaxy, [[Anime/DemashitaPowerpuffGirlsZ "Him"]].
*** After Him is defeated, [[Anime/CodeGeass Mao]] comes from the future to tell Guilmon that two androids, [[Manga/SaintSeiya Black Pegasus]] and [[VisualNovel/HigurashiWhenTheyCry Miyo Takano]], will arrive in three years to kill everyone. What Mao did not expect was a third android, [[Anime/YuGiOh Seto Kaiba with green hair]] (or [[VideoGame/FireEmblemShadowDragonAndTheBladeOfLight Mar]][[VideoGame/SuperSmashBros th]]), as well as a much bigger threat, [[Manga/ZatchBell Victoream]].
*** Several years later, Guilmon's now grown-up son [[Manga/GalaxyExpress999 Tetsuro]] is now going to high school and ends up donning the identity of a superhero, but runs across [[Manga/SailorMoon Sailor Saturn]], the daughter of [[Anime/CowboyBebop Jet Black]], who ends up discovering who he really is. Saturn challenges Tetsuro to the World Martial Arts Tournament, and it isn't long before all of his follow fighters enter the tournament as well as Guilmon, who is allowed to return to Earth for one day. But all that must be put on hold when the gang is enlisted by [[Manga/{{Touch}} Tatsuya Uesugi]] into stopping [[Manga/OnePiece Wapol and his henchman Crocodile]] from awakening the creature [[Manga/SlamDunk Kazushi Hasegawa]] in what soon becomes a battle for the fate of the universe itself.
* ''LightNovel/DragonCrisis'': [[Manga/TheWorldGodOnlyKnows Keima Katsuragi]] is an ordinary high school student until [[Anime/CodeGeass C.C.]], his second cousin returns from America forcing him to join her unauthorized organization. The two intercept a trade and discover what was being traded - RubyGloom.
* ''{{LightNovel/Durarara}}'': [[LightNovel/{{Kanokon}} Tayura Minamoto]], at the invitation of his friend [[Manga/DeathNote Light Yagami]], transfers to a school in Tokyo. Tayura then witnesses an urban legend on his first day in the city: a headless [[Manga/{{Beelzebub}} Satanic baby]]. [[Manga/JoJosBizarreAdventure Jotaro Kujo]] has a short temper, ''especially'' regarding [[VisualNovel/FateStayNight Shinji Matou]].

!!E
* ''Anime/EurekaSeven'': [[Manga/{{Saki}} Kazue Nanpo]] falls in love with mysterious mecha pilot [[Anime/SoulEater Tsubaki]] and joins an anti-military group including [[Anime/ChronoCrusade Satella Harvenheit]], [[Anime/TigerAndBunny Jake Martinez]] and [[Anime/DigimonAdventure Etemon]].
* ''Anime/ExcelSaga'': [[Manga/OnePiece Boa Hancock]] and [[Anime/CodeGeass Euphemia li Britannia]] are two agents of [[Anime/SoulEater Excalibur]], who intends to take over a city.

!!F
* ''VisualNovel/FateStayNight'': [[Manga/{{Naruto}} Sasuke Uchiha]], who's best friends with [[LightNovel/{{Durarara}} Izaya Orihara]],[[VideoGame/Persona4 Tohru Adachi]], and [[LightNovel/InfiniteStratos Maya Yamada]], accidentally summons [[Manga/PandoraHearts Alice]] (after being attacked by [[Manga/{{Berserk}} Guts]]) and then allies with [[VideoGame/BlazBlue Rachel Alucard]] and [[Manga/BlackButler The Undertaker]] to participate in a Battle Royale for the Holy Grail, facing off against [[Manga/AzumangaDaioh Sakaki]], [[Manga/{{Inuyasha}} Seiryu]], [[Anime/StrikeWitches Sanya V Litvyak]], Anime/MDGeist, [[Manga/FullmetalAlchemist Roy Mustang]], VideoGame/{{Bayonetta}}, [[spoiler: and finally [[Manga/{{Hellsing}} Alucard]] and [[Anime/FruitsBasket Kyo Sohma]]]].
** ''VisualNovel/FateZero'': Ten years earlier, [[VisualNovel/DanganRonpa Jin Kirigiri]] summoned Alice after being hired by [[Manga/FairyTale Erza Scarlet]]'s family to compete in the Holy Grail War against two other clans headed by [[WesternAnimation/YoungJustice Super Boy]] and [[Manga/DragonBallZ Zarbon]]. Now he and Alice must compete against [[Franchise/MetalGear Solid Snake]], [[Anime/FullmetalAlchemist Scar]], [[LightNovel/TheSlayers Zelgadis Graywords]], [[VideoGame/StreetFighter Balrog]], [[spoiler: and eventually the StartOfDarkness for Alucard and Kyo]].
** ''Manga/FateKaleidlinerPrismaIllya'': Meanwhile in an AlternateUniverse, Sanya and Rachel are [[MagicalGirl Magical Girls]] along with [[Anime/CodeGeass Nunnally Lamperouge]] and [[Manga/HayateTheCombatButler Hinagiku Katsura]] that must fight evil spirits. Sanya's wands [[MythologyGag are]] [[VideoGame/MeltyBlood Kohaku and Hisui]].
** ''Anime/FatePrototype'': Meanwhile in [[WhatCouldHaveBeen another alternate universe]], [[Manga/PrincessJellyfish Tsukimi Kurashita]] accidentally summons [[Anime/CodeGeass Suzaku Kururugi]] and now must battle the forces of [[Anime/RevolutionaryGirlUtena Touga Kiryuu]], [[Manga/KOn Yui Hirasawa]], [[Anime/PuellaMagiMadokaMagica Homura Akemi]] and [[Manga/XxxHolic Doumeki]], and [[Manga/DeathNote Light Yagami]] and [[Manga/CardCaptorSakura Yukito Tsukishiro]].
* ''Manga/FistOfTheNorthStar'' In a post-apocalyptic Earth previously ravaged by nuclear war, [[Manga/CityHunter Ryo Saeba]], successor to the deadly Hokuto Shinken martial art style, emerges as its savior. With his traveling companions [[Manga/CrayonShinChan Masao-kun]] and [[Anime/{{Pokemon}} Jirachi]], he initially travels to win back his love Manga/SallyTheWitch, who was taken from him by friend turned rival, Nanto Seiken practitioner [[Anime/DragonBallZ Piccolo]]. Later, he encounters opposition and assistance by several other Nanto Seiken masters: [[LightNovel/VampireHunterD D]], [[VideoGame/MetalGearSolid Liquid Snake]], [[Anime/SpeedRacer Go Mifune]] and [[VideoGame/DeadOrAlive Zack]]. Also, he reunites with his brothers and fellow Hokuto Shinken practitioners, the heartless [[VideoGame/{{Persona3}} Takeharu Kirijo]], the benevolent [[Film/HarryPotter Severus Snape]], and the ambitious [[Anime/NeoHumanCasshern Braiking Boss]], who seeks to become the soul Hokuto Shinken master and ruler of Earth/The Heavens, establishing himself as the BigBad.
* ''Anime/{{FLCL}}'': [[Anime/KillLaKill Nonon Jakuzure]] is an [[spoiler: AxCrazy]] ManicPixieDreamGirl...who is also a SpaceCop. Yes it's [[WidgetSeries that kind of anime]].
* ''Anime/{{Free}}'': [[Anime/DateALive Shido Itsuka]], [[VideoGame/FinalFantasyXV Noctis]], [[VideoGame/ArcanaFamiglia Nova]], and [[Manga/JoJosBizarreAdventure Noriaki Kakyoin]] form a swimming club and competes against a rival school consisting of [[Manga/SoulEater Death the Kid]], [[Anime/YuGiOh Seto Kaiba]], [[Franchise/DanganRonpa Kazuichi Soda]], [[LightNovel/BakaAndTest Kouta Tsuchiya]], and [[Anime/OsomatsuSan Iyami]]. Death's sister Liz is the CuteSportsClubManager of Shido's team.
* ''Manga/FruitsBasket'': [[Manga/LoveHina Naru Narusegawa]] is a girl who ends up as a live in maid with [[Anime/CardcaptorSakura Keroberos]] the rat, [[Manga/{{Chobits}} Hiromu Shinbo]] the cat and [[Manga/{{Bleach}} Byakuya Kuchiki]] the dog. Other members of their family include Anime/SailorMoon the boar, [[Manga/OuranHighSchoolHostClub Honey]] the rabbit, [[Manga/{{Naruto}} Kakashi Hatake]] the seahorse, [[WesternAnimation/{{Doug}} Roger Klotz]] the cow, [[Disney/TheLionKing Simba]] the snake, [[Manga/DaaDaaDaa Miyu Kozuki]] the tiger, [[Manga/MaisonIkkouku Ibuki Yagami]] the ram, and [[Disney/TheBlackCauldron Ellonwy]] the monkey. Naru's best friends are former gang member [[Manga/WeddingPeach Angel Salvia]] and psychic [[Anime/KazemakaseTsukikageRan Ran Tsukikage]].
* ''Anime/FullmetalAlchemist'': [[Manga/{{Naruto}} Temari]] and her younger sister [[LightNovel/ShakuganNoShana Shana]] attempt to get their bodies back by using a mysterious stone. Along the way, [[Series/{{Teletubbies}} Tinky Winky]] wants to kill them.
** ''Manga/FullmetalAlchemist: Brotherhood'': More of the same, but Tinky has become Disney/{{Aladdin}}.
* ''LightNovel/FullMetalPanic'': [[Manga/NodameCantabile Shinichi Chiaki]] is a ChildSoldier who is assigned, alongside with his team mate [[Manga/FullmetalAlchemist Roy Mustang]] and leader [[LightNovel/TheFamiliarOfZero Agnes Chevalier de Milan]], by [[Manga/DetectiveConan Inspector Yokomizo]] to guard [[Manga/{{Inuyasha}} Kagome Higurashi]] from overseas threats. Meanwhile, Inspector Yokomizo works in a [[CoolBoat highly advanced submarine]] with its [[TheCaptain captain]] [[Anime/CodeGeass C.C.]] and her executive officer [[Manga/ChronoCrusade Edward "The Elder" Hamilton]] to eliminate the source of those threats.
* ''Manga/FushigiYuugi'': [[VideoGame/{{Darkstalkers}} Felicia]] and [[Manga/AhMyGoddess Urd]] get sucked into the novel's universe, but Felicia gets stuck into said universe and she later falls in love with [[LightNovel/{{Slayers}} Zelgadis Greywords]]. The other Suzaku warriors includes [[Anime/ExcelSaga Il Palazzo]], [[Anime/SailorMoon Sailor Star Healer]], [[LightNovel/FullMetalPanic Sousuke Sagara]], [[SonicTheHedgehog Knuckles]], [[VideoGame/FatalFury Yamazaki]] and [[Anime/RevolutionaryGirlUtena Utena]], who must defeat [[Manga/TriGun Millions Knives]] and his minions.
* ''Anime/FutureDiary'': [[Manga/{{Nichijou}} Mai Minakami]] and [[Anime/TheLegendOfTheLegendaryHeroes Iris Eris]] are summoned by [[Manga/AzumangaDaioh Chiyo's Father]] to compete with several others in [[ThereCanBeOnlyOne a Survival Game to see who will succeed him as God]]. Other participants include (in numerical order) [[Manga/StraitJacket George Thomson]],[[VideoGame/DynastyWarriorsGundam M'Quve]], [[Manga/RozenMaiden Jun Sakurada]],[[Anime/LoveChunibyoAndOtherDelusions Toka Takanashi]], [[VisualNovel/FateStayNight Gilgamesh]] and [[LightNovel/HaruhiSuzumiya Ryoko Asakura]], [[Manga/LuckyStar Akira Kogami, Ayano Minegishi, Soujiro Izumi]], [[Anime/TheVisionOfEscaflowne Leon Schezar]], and [[LightNovel/ACertainMagicalIndex Pierce Aogami]]. Mai is in a [[spoiler: [[PsychoticLoveTriangle Psychotic]]]] LoveTriangle with Iris and [[VideoGame/Persona3 Makoto Yuki]].
* ''Anime/FutureGPXCyberFormula'': [[Anime/{{Pokemon}} Harley]] becomes a racer after he rescues [[Manga/OnePiece Mr. 11]] from thieves. Anime/SailorMoon is a [[PitGirls race queen]] and [[Anime/MobileSuitGundamWing Heero Yuy]], [[Anime/RanmaOneHalf Mousse]], [[Manga/{{Bleach}} Sosuke Aizen]], [[Anime/DragonBallZ Broly]], [[VideoGame/MegaManX Zero]] and [[Manga/DragonBall Oolong]] are also racers.

!!G
* ''Anime/{{Gankutsuou}}'': A version of ''Literature/TheCountOfMonteCristo'' '''''InSpace!''''' [[Anime/CodeGeass Lelouch]] and [[VisualNovel/SchoolDays Makoto Ito]] are best friends who meet [[VideoGame/MarvelVsCapcom3 Albert Wesker]] one night at a space party. Murder ensues.
* ''Anime/GargantiaOnTheVerdurousPlanet'': [[LightNovel/TokyoRavens Harutora Tsuchimikado]] and his HumongousMecha [[Manga/{{Gintama}} Gintoki Sakata]] rediscover Earth, the long-lost homeworld of humanity, and become friends with people like [[Anime/SailorMoonCrystal Sailor Mercury]], [[Manga/ShamanKing Amidamaru]], [[LightNovel/ACertainMagicalIndex Kaori Kanzaki]] and [[Anime/AldnoahZero Yuki Kaizuka]]. Harutora's commanding officer, [[Manga/MonthlyGirlsNozakiKun Masayuki Hori]] and his HumongousMecha [[Manga/MaidSama Misaki Ayuzawa]] land on another part of the planet and they all have a climactic battle.
* ''Manga/GeGeGeNoKitaro'': [[Anime/{{Voltron}} Pidge]] is a one-eyed ghost-child thing who protects humans in danger from yokai of Japanese folklore. His father is a [[Anime/SazaeSan ceiling mouse]] who lives in his eye socket. He's sometimes friends with half-yokai [[Film/TheGoodtheBadandtheUgly Tuco]]. In Episode 20 Pidge employs [[Manga/{{Kinnikuman}} Sayuri Kinniku]] to threaten Tuco out of his latest scheme for his own good. Manga/SazaeSan sings the ending theme song.
** ''(1985 anime)'' [[ToyStory Bo Peep]] and [[AllDogsGotoHeaven Charlie B. Barkin]] are supernatural frenemies.
* ''Anime/GhostStories'': [[Anime/RevolutionaryGirlUtena Utena Tenjou]] finds her mother's old spellbook. She gathers her friends [[Manga/{{Bleach}} Kinta Hanakari]], [[Manga/TokyoMewMew Mew Aqua]], Manga/AstroBoy, Utena's brother Anime/{{Hamtaro}}, and a demon cat named [[Manga/{{Hellsing}} Alucard]] to save the world.
* ''Anime/{{Gigantor}}'': Casts of characters vary in different versions.
** 1963 version has [[Anime/KotetsuJeeg Queen Himika]] taking the control of Tetsujin 28. [[Manga/MazingerZ Dr. Hell]] was an Inspector.
** 1980s version has [[Manga/DragonBall Mai]] with it. [[VideoGame/SuperRobotWarsZ Anborn Jeus]] was his girlfriend and [[Manga/MazingerZ Dr. Hell]] was still a comedic inspector. Not to mention [[Anime/ShinMazinger Hades]] and [[Anime/MobileSuitGundam Matilda Ajan]] were among the major villains of the series.
** 2004 series has [[WesternAnimation/MyLittlePonyFriendshipIsMagic Spike]] took the control of Tetsujin.
* ''Manga/{{Gintama}}'': [[VideoGame/BlazBlue Ragna the Bloodege]], [[LightNovel/{{Baccano}} Jacuzzi Splot]], [[Manga/MahouSenseiNegima Tsukuyomi]], and their gigantic dog [[LightNovel/TheFamiliarOfZero Montmorency]], take various odd jobs in order to pay their rent from the landlord, [[Manga/{{Naruto}} Orochimaru]].
* ''Anime/GirlsUndPanzer'': in an interschool competition in which teams of girls operate [[TankGoodness tanks]], one team consisting of [[Anime/DokiDokiPreCure Alice Yotsuba]], [[LightNovel/{{Durarara}} Maomin]], [[Anime/TanteiOperaMilkyHolmes Keiko Totsugawa]], [[Manga/{{Sekirei}} Oriha]] and a gunner competes with their school's existence at stake.
* ''LightNovel/GonnaBeTheTwinTail'': [[Series/GameOfThrones Joffrey Baratheon]] is a guy who love twin-tails, until he meets a girl named [[VideoGame/GranblueFantasy Anchira]] who transform him into [[VideoGame/LeagueOfLegends Jinx]].
* ''Anime/GlassMask'' (1984): [[WesternAnimation/{{Recess}} Alordayne Grotke]] is girl with a dream to act, so she runs away from home to attend an acting school. Her talent is noted by the [[Anime/SailorMoon Makaiju]], and wants Miss Grotke to ressurect the role in a play she was going to star in before a stage accident and health problems made her stop acting. However, Makaiju also has her eyes on professional actress [[Anime/LittleLulu Lulu]], who just wants to succeed on her own.
* ''Anime/TheGreatMissionToSavePrincessPeach'': [[Anime/SailorMoon Tuxedo Mask]] falls in love with [[WesternAnimation/TheBraveLittleToaster Toaster]], who is captured by [[WesternAnimation/TheSimpsonsMovie Marge Simpson]]. [[spoiler: Finally, when Tuxedo Mask and his brother [[WesternAnimation/{{JohnnyTest}} Johnny Test]] do save her, it turns out that Toaster is engaged to [[Manga/ZatchBell Kyanchome]].]]
* ''Manga/GreatTeacherOnizuka'': [[Manga/HajimeNoIppo Masaru Aoki]] is an ex-{{delinquent}} who became a high school teacher. Among his class are {{Teen Genius}}es [[Anime/MobileSuitGundamWing Heero Yuy]] and Anime/SailorMoon, MommasBoy [[LightNovel/FullMetalPanic Sousuke Sagara]], ditzy [[VisualNovel/FateStayNight Saber]], [[Manga/FlameOfRecca Recca]] who's always bullied by [[Manga/OnePiece Nami]], and Aoki's constant antagonist [[Anime/DigimonAdventure02 Veemon]].
* ''Anime/{{Grenadier}}'': Busty Gunslinger [[Anime/MagicalGirlLyricalNanoha Caro Ru Lushe]] is on a journey to learn the Ultimate Battle Strategy. She is joined by Samurai [[Anime/SamuraiChamploo Mugen]] and Balloon Maker [[Manga/AzumangaDaioh Ayumu Kasuga]].
* ''Franchise/{{Gundam}}''
** ''Anime/MobileSuitGundam'': [[Manga/SaintSeiya Pegasus Seiya]] gets drafted into [[Anime/{{Daitarn 3}} Banjou Haran's]] battleship to fight against [[Manga/FistOfTheNorthStar Souther's]] empire, whose [[TheDragon dragon]] is [[Anime/RurouniKenshin Hiko Seijurou]], who plots to overthrow Souther's empire (and he's done that to Souther's brother [[Anime/ScienceNinjaTeamGatchaman Ken The Eagle]]). Seiya [[GetAHoldOfYourselfMan gets slapped to shape by Banjou]]. Both Seiya and Hiko fell for [[Manga/SaintSeiya Athena]], but then Seiya accidentally killed Athena.
** ''Anime/MobileFighterGGundam'': [[VideoGame/MarvelVsCapcom3 Viewtiful Joe]] travels around the world with [[Anime/TenchiMuyo Kiyone Makibi]] to look for his brother [[Manga/OnePiece Bartholomew Kuma]]. Giant robots are involved.
** ''Anime/MobileSuitGundamWing'': [[Manga/FushigiYuugi Tamahome]] was sent to Earth for a mission. He was attacked and was found by [[VideoGame/{{Persona 2}} Maya Amano]] and she developed an attraction to him. He doesn't seem to like it and he threatens to kill her. On missions, he is eventually accompanied by his comrades [[Anime/RanmaOneHalf Mousse]], [[Anime/DragonBallZ Android 17]], [[Anime/{{Beyblade}} Max Mizuhara]] and [[VideoGame/SengokuBasara Chousokabe Motochika]].
** ''Anime/AfterWarGundamX'': [[Manga/GreatTeacherOnizuka Eikichi Onizuka]] rescues [[Anime/GalaxyAngel Vanilla H]] and joins [[Manga/{{Naruto}} Pain's]] gang. They are constantly persisted by brothers [[Manga/{{Inuyasha}} Naraku]] and [[Manga/YuYuHakusho Yusuke]].
** ''Anime/TurnAGundam'': The three "hometown friends" from this series would later go on to change the world on their own:
*** [[Creator/RomiPark Loran]] becomes a [[Manga/FullmetalAlchemist state alchemist and saves the world]].
*** [[Creator/KumikoWatanabe Fran Doll]] tries to [[Manga/SgtFrog take it over]].
*** [[Creator/JunFukuyama Keith]] actually succeeds in [[Anime/CodeGeass taking it over]].
** ''Anime/MobileSuitGundamSEED'': Childhood friends [[Manga/SteamDetectives Narutaki]] and [[Manga/ElementalGelade Coud]] are forced to fight each other in war. [[spoiler:They eventually join forces.]]
*** ''Anime/MobileSuitGundamSeedDestiny'': Coud returns with his girlfriend [[Anime/MaiHime Shizuru]] to have a peace meeting with PLANT chairman [[Manga/OnePiece Shanks]], but the trio of [[Manga/{{Bleach}} Grimmjow]], [[VideoGame/FinalFantasyX Tidus]] and [[Manga/AzumangaDaioh Kagura]] led by [[Anime/WeissKreuz Ran "Aya" Fujimiya]], stole three mechas and caused havoc. Coud decides to fight, but is outnumbered. Luckily, [[Anime/DGrayMan Lavi]] came to his aid, along with his pals [[Anime/TheVisionOfEscaflowne Hitomi]] and [[{{Manga/Saiyuki}} Sanzo]].
** ''Anime/MobileSuitGundam00'': Season 1 features [[VideoGame/KingdomHearts Riku]], [[Manga/InitialD Takumi Fujiwara]], [[Anime/{{Vandread}} Hibiki Tokai]] and [[Manga/SayonaraZetsubouSensei Nozomu Itoshiki]] fighting all factions of the world to unite them. Season 2 features [[RelationshipVoiceActor Riku reuniting with Sora]] and eventually co-piloting the titular machine. The machine is armed with GN Swords and ThePowerOfFriendship. Together with their new teammates [[Manga/{{Bleach}} Kisuke]] ([[spoiler:Takumi's BackupTwin]]) and [[Anime/WolfsRain Cheza]] ([[spoiler:Hibiki's [[BattleCouple girl]][[VictoriousChildhoodFriend friend]]]]), they fight [[Manga/DragonBall Yamcha]] and his sissy goons.
** ''Anime/GundamBuildFighters'': [[Anime/{{Heroman}} Joey]] is good Gundam builder but is a terrible fighter. [[Anime/GingaDensetsuWeed Weed]] suddenly joins him to help. [[Manga/AttackOnTitan Mikasa]] then also joins Joey, along with [[VisualNovel/{{Clannad}} Tomoya]] and [[Anime/GingaEKickoff Ryuji]] as a scientist.
** ''Anime/MobileSuitGundamIronBloodedOrphans'': [[Manga/SangatsuNoLion Rei Kiriyama]] is a child soldier for [=CGS=] in Mars. When his friend [[Manga/{{Chihayafuru}} Arata Wataya]] declares a coup against the management of [=CGS=], he immediately joins him, together [[Anime/AldnoahZero Inaho Kaizuka]]. Meanwhile, [[LightNovel/ACertainMagicalIndex Sasha Kreuzhev]] visits the [=CGS=] to ask for escort. [[Anime/CodeGeass Suzaku Kururugi]] and [[Anime/DeateNote Teru Minami]] are observing the situation in Mars.

!!H
* ''Manga/HajimeNoIppo'': [[Manga/ThePrinceOfTennis Kaoru Kaidou]] is being beaten up by [[Anime/CodeGeass Kaname Ohgi]] and his pals when pro-boxer [[Anime/{{Witchblade}} Reiji Takayama]] intervenes. Takayama took Kaido to the gym and from then on, Kaido decided to become a boxer to discover the true meaning of strength.
* ''LightNovel/HaruhiSuzumiya'': [[Manga/TheDaughterOfTwentyFaces Chiko]] forces [[RaidouKuzunohaVsKingAbaddon Raidou Kuzunoha]] to join her club. [[Manga/MinamiKe Chiaki]], [[VisualNovel/{{Shuffle}} Kaede]] and [[Manga/BlackButler Sebastian Michaellis]] also join.
** ''[[Anime/HaruhiChan Nyoron Churuya-san]]'': [[Manga/AzumangaDaioh Osaka]] is a super {{Moe}} ButtMonkey.
* ''Manga/HayateTheCombatButler'': After [[Manga/{{Hellsing}} Schrodinger]]'s parents sell him to some [[{{Yakuza}} "nice people"]], he's forced to become a butler to [[VideoGame/Persona4 Rise Kujikawa]] along with [[Manga/RozenMaiden Suigintou]]. Also starring [[LightNovel/OokamiSan Ryoko Okami]] and narrated by [[Manga/CromartieHighSchool Mechazawa]].
* ''LightNovel/HaiyoreNyarukoSan'': [[LightNovel/{{Toradora}} Ami Kawashima]] is an OrdinaryHighSchoolStudent who gains an UnwantedHarem of humanoid abominations consisting of [[Anime/PuellaMagiMadokaMagica Nagisa Momoe]], [[LightNovel/{{Shimoneta}} Anna Nishikinomiya]], and [[Manga/FullmetalAlchemist Alphonse Elric]].
* ''Manga/HeavensLostProperty'': Local pervert [[Anime/MobileSuitGundamSeed Kira Yamato]] finds a mysterious girl named [[Anime/EdenOfTheEast Saki Morimi]], who she sees as her master. At times, Kira will transform into his female counterpart [[Music/{{Vocaloid}} Hatsune Miku]] in order to do more perverted things.
* ''Anime/HellGirl'': [[VisualNovel/{{Clannad}} Kotomi Ichinose]] delivers divine retribution to both the [[AssholeVictim Asshole]] VictimOfTheWeek and (when they die) the person who cursed them via the Internet.
* ''Anime/{{Hellsing}}'': [[Anime/{{Gankutsuou}} Edmond Dantes]] is a vampire under the control of [[Anime/SailorMoon Queen Nehellenia]].[[{{Manga/Bleach}} Rukia Kuchiki]] is a policewoman who is turned into a vampire. Along with Roeas' BattleButler [[Anime/TheBigO Norman Burg]] and , they fight people such as Father [[Manga/NininGaShinobuden Onsokumaru]].
** ''[[Manga/{{Hellsing}} Hellsing Ultimate]]'': Mostly the same except Onsokumaru is [[TheOtherDarrin now]] [[Anime/FutureDiary Deus Ex Machina]] and they have to fight a legion of ThoseWackyNazis led by [[Anime/CodeGeass Clovis la Britanna]] and includes [[Manga/{{Naruto}} Gamabunta]], [[Manga/HayateTheCombatButler Hayate Ayazaki]], [[VideoGame/Persona3 Aegis]], and [[Manga/FullmetalAlchemist Olivier Mira Armstrong]].
* ''Manga/HidamariSketch'': [[Anime/TengenToppaGurrenLagann Kiyal]] gets into the art department of a private high school whose principal is the constantly-trembling [[Anime/DigimonFrontier Nanomon]], and moves into the apartments across the street, where she befriends fellow first-year [[Anime/ALittleSnowFairySugar Pepper]], and their sempai, the motherly [[LightNovel/HaruhiSuzumiya Mikuru Asahina]] and more reticent flat chested {{Meganekko}} [[Anime/GalaxyAngel Milfeulle Sakuraba]]. (The apartments, incidentally, are run by [[Anime/DiGiCharat Puchiko]].) The first-years have [[Anime/FutariWaPrettyCureSplashStar Choppy]] for an art teacher. Milfeulle is occasionally visited by little sister [[Anime/DigimonSavers Ikuto Noguchi]], and has a rivalry with [[Manga/ToLoveRu Golden Darkness]]. When they move up to the next year, the four are joined in the apartments by new first-years [[Manga/{{Bleach}} Menoly]], who's in the art department, and [[Anime/SoulEater Maka Albarn]], who's not.
* ''LightNovel/HighSchoolDXD'': [[VideoGame/FinalFantasyXIII Hope Estheim]] gets killed by [[Manga/HayateTheCombatButler Yukiji Katsuragi]] but gets revived as a devil by [[Manga/DailyLivesOfHighSchoolBoys The Literature Girl]]. She then invites him on her club composed of herself, [[LightNovel/ACertainMagicalIndex Kaori Kanzaki]], [[VideoGame/DigitalDevilSaga Serph Sheffield]], and [[VideoGame/TrinityUniverse Tsubaki]]. They're latter joined by [[Anime/TheIdolMaster Yukiho Hagiwara]].
* ''Manga/HighSchoolOfTheDead'': [[VisualNovel/FateStayNight Archer]], [[LightNovel/{{Kampfer}} Senou Natsuru]], [[Anime/GaoGaiGar Guy Shishioh]], [[Anime/TengenToppaGurrenLagann Nia]], [[LightNovel/{{Durarara}} Celty Sturluson]], and [[LightNovel/{{Bakemonogatari}} Karen Araragi]] fight zombies.
* ''VisualNovel/HigurashiWhenTheyCry'': [[Anime/MobileSuitGundamSeed Kira Yamato]], [[LightNovel/LadiesVersusButlers Sernia Iori Flameheart]], [[Manga/{{Inuyasha}} Kagome Higurashi]], [[Anime/CodeGeass Kaguya Sumeragi]], and [[Manga/BGataHKei Yamada]] are all stuck in a murder mystery.
* ''Manga/HimoutoUmaruChan'': [[Anime/SailorMoonCrystal Tuxedo Mask]]'s [[TheAce seemingly perfect]] sister [[VisualNovel/NewDanganRonpaV3 Himiko Yumeno]] turns out to be a lazy, [[ClosetGeek closeted otaku]].
* ''Manga/HappyHappyClover'': [[LightNovel/{{Akikan}} Melon]] is a hyperactive bunny who befriends [[VisualNovel/{{SchoolDays}} Kotonoha Katsura]], along with [[Manga/{{SoulEater}} Black☆Star]] and [[LightNovel/{{CatPlanetCuties}} Sara]] who's babysitter is [[{{Manga/ZatchBell}} Reira]] and dreams on traveling with [[{{Manga/SoulEater}} Excalibur]].

!!I
* ''Manga/ICantUnderstandWhatMyHusbandIsSaying'': [[VisualNovel/HigurashiWhenTheyCry Rika Furude]] is an OfficeLady married to {{Otaku}} [[LightNovel/KaraNoKyoukai Mikiya Kokutou]]. HilarityEnsues.
* ''Anime/TheIdolmaster'': Join [[Anime/ShinMazinger Kouji Kabuto]] as he is drafted by [[Manga/{{Naruto}} Jiraiya]] to produce IdolSinger like overly average [[VisualNovel/KoihimeMusou Enjutsu]], super-serious-in-singing [[VisualNovel/SteinsGate Kurisu Makise]], super-shy [[TheOtherDarrin formerly-known-as-]][[VideoGame/DisgaeaHourOfDarkness Thursday the Robot]], hyperactive [[VideoGame/ArcanaHeart Lilica Felchenrow]], ditzy [[VideoGame/BlazBlue Litchi Faye-Ling]], haughty little [[TheOjou Ojou-sama]] [[VideoGame/{{Persona 4}} Rise Kujikawa]], tomboyish [[VideoGame/ArcanaHeart Kamui Tokinomiya]], twin girls [[Music/{{Vocaloid}} Rin & Len Kagamine]], amongst others... He is also assisted by [[VideoGame/FireEmblemPathOfRadiance Princess Elincia of Crimea]] as his secretary, and must also endure the antagonism made by [[ValkyrieProfile Lezard Valeth]].
** ''Anime/TheIdolmasterCinderellaGirls'': [[VideoGame/{{Caligula}} Shogo Satake]] is now tasked with producing a new generation of idols including the {{Moe}} {{NEET}} [[VideoGame/SenranKagura Minori]], delusional Gothic Lolita [[Anime/LoveChunibyoAndOtherDelusions Rikka Takanashi]], hyperactive [[VideoGame/FireEmblemFates Olivie]], FragileFlower [[Manga/{{Noucome}} Yuragi Hakoniwa]], icy Russian [[VideoGame/LeagueOfLegends Jinx]], spicy kogal [[LightNovel/{{Haganai}} Yukimura Kusunoki]], baking master [[Anime/NoRin Akari "Bio" Suzuki]], talkative [[Anime/KillLaKill Mako Mankanshoku]], cat lover [[LightNovel/{{Another}} Mei Misaki]], among others.
* ''LightNovel/InfiniteStratos'': [[VideoGame/KingdomHeartsBirthBySleep Ventus is tutored by Aqua]] and [[VisualNovel/FateStayNight Sakura Matou]] on how to pilot a PoweredArmor. Ventus must also deal with the hearts of his fellow colleagues [[Anime/OccultAcademy Maya Kumashiro]], [[Series/KamenRiderOOO Mezool]], [[Anime/TheIdolmaster the Futami twins]], Anime/BlackRockShooter and [[Anime/TengenToppaGurrenLagann Yoko Littner]], all pounding on him like Heartless.
* ''Manga/{{Inuyasha}}'': [[Manga/OnePiece Usopp]], a half-demon living in Feudal Japan, falls in love with [[Manga/{{Trigun}} Milly Thompson]], a high school student who finds herself transported back into the past. Along the way, they befriend perverted monk [[Anime/IrresponsibleCaptainTylor Justy Ueki Tylor]], mighty demon hunter [[Manga/AzumangaDaioh Kagura]] (who falls in love with Tylor), and the fox demon [[Manga/SgtFrog Sgt. Keroro]]. They also frequently encounter Usopp's brother [[Anime/CodeGeass Jeremiah "Orange-kun" Gottwald]] and the prideful wolf demon [[Manga/TheKindaichiCaseFiles Kindaichi]]. They're doing all of this to stop the demented [[VideoGame/FinalFantasyVII Sephiroth]].
* ''Anime/IsThisAZombie'': After [[LightNovel/{{Toradora}} Ryuji Takasu]] is resurrected by [[Anime/DateALive Mii Fujibakama]], he accidentally absorbs [[Anime/HeavensLostProperty Nymph]]'s powers and has to become a [[DraggedIntoDrag crossdressing]] MagicalGirl.
** Ryuji fantasizes Mii as Manga/SailorMoon, [[Anime/CodeGeass Kaguya Sumeragi]], [[Manga/AzumangaDaioh Chiyo Mihama]], [[Manga/DragonBallZ Videl]], [[VisualNovel/{{Clannad}} Ushio Okazaki]], [[Manga/CardCaptorSakura Sakura Kinomoto]], [[LightNovel/HaruhiSuzumiya Tsuruya]], [[Manga/{{Inuyasha}} Kikyo]], and [[LightNovel/InfiniteStratos Squall Meusel]]. And that's just Season 1!

!!J
* ''{{Franchise/Jewelpet}}'': [[Manga/FruitsBasket Momiji]] [[Creator/AyakaSaitou Sohma]], LightNovel/{{Haruhi|Suzumiya}} [[Creator/AyaHirano Suzumiya]] and [[Manga/LuckyStar Patricia "Patty" Martin]] are partnered with Eri Kamei, AKINA and [[WesternAnimation/MyLittlePonyFriendshipIsMagic Twilight]] [[Creator/MiyukiSawashiro Sparkle]] to find lost Jewel Charms with the help from [[Creator/MamoruMiyano Setsuna]] [[Anime/MobileSuitGundam00 F.Seiei]]. While stopping [[Anime/OjamajoDoremi Onpu]] [[Creator/RumiShishido Segawa]] from getting them and later on stopping the plans of the powerful yet tyrannical Jewelpet named [[Anime/CodeGeass Lelouch]] [[Creator/JunFukuyama vi Brittania]]!
* ''Manga/JoJosBizarreAdventure''
** 1993 OVA/Adventure Adventure: [[Anime/RevolutionaryGirlUtena Akio Ohtori]] who believes himself to be possessed by an evil spirit, is greeted by his grandfather, [[VideoGame/KingdomHearts Master Xehanort]] and [[Manga/DeathNote Watari]] an Egyptian fortune teller who tells Akio that the spirit is the cause of [[WesternAnimation/BatmanTheAnimatedSeries The Gray Ghost]]'s head attached to his ancestor and gaining a Stand. Later, Akio's mother [[Manga/RanmaOneHalf Shampoo]] falls sick because of her stand. They are also joined later by [[Manga/DragonBallZ Tien Shinhan]] to save Shampoo.
** 2010's Series
*** ''Phantom Blood'': After [[VideoGame/{{Overwatch}} Lucio]]'s foster brother Manga/BoboboboBobobo turns into a vampire and [[YouKilledMyFather kills their father]], he teams up with [[WesternAnimation/TeenageMutantNinjaTurtles1987 Raphael]] and [[WebComic/OnePunchMan Drive Knight]] to stop him.
*** ''Stardust Crusaders'': [[LightNovel/{{Durarara}} Shizuo Heiwajima]] who believes himself to be possessed by an evil spirit, is greeted by his grandfather, [[Anime/CowboyBebop Jet Black]] and [[Manga/FullmetalAlchemist Scar]] an Egyptian fortune teller who tells Shizuo that the spirit is the cause of Bobobo-bo Bo-bobo's head attached to his ancestor and gaining a Stand. Later, Shizuo's mother [[Manga/LoveHina Kaolla Su]] falls sick because of her stand. They are also joined later by [[Anime/{{Free}} Rei Ryugazaki]] to save Kaolla.

!!K
* ''Anime/{{K}}'': [[Webcomic/AxisPowersHetalia Italy]] is being chased two opposing groups, the Red clan (led by [[Anime/YuGiOh Seto Kaiba]] and composed of [[Anime/CodeGeass Suzaku Kururugi]], [[VisualNovel/UminekoWhenTheyCry Maria Ushiromiya]], [[Manga/XxxHolic Kimihiro Watanuki]] and [[Anime/MacrossFrontier Alto Saotome]]) and the Blue clan (led by [[Manga/{{Gintama}} Gintoki Sakata]] and composed of [[LightNovel/{{Durarara}} Celty Sturluson]] and [[Manga/DeathNote Light Yagami]]). Then, he meets [[Manga/BlackButler Sebastian Michaelis]] and [[LightNovel/BodaciousSpacePirates Marika Katou]].
** ''More Kings'': Now they must face off against the Green Clan (led by [[Manga/PrisonSchool Andre]]) consisting of [[Manga/{{Bleach}} Ichigo Kurosaki]], [[Manga/TokyoGhoul Juzo Suzuya]], [[Manga/TheWorldGodOnlyKnows Keima Katsuragi]], among others.
* ''Literature/KaiketsuZorori'' (Series): [[{{Disney/Aladdin}} Genie]] wants world domination.
** (Film) [[{{Disney/Aladdin}} Iago]] becomes a wizard's apprentice to try and achieve world domination.
* ''Anime/KamisamaMinaraiHimitsuNoCocotama'': [[Anime/RegaliaTheThreeSacredStars Yui]] is a fifth grader who likes to take care of her things until [[Manga/HunterXHunter Gon Freecss]] was born from her colored pencil set and got accidentally discovered by her. She must agree to sign his contract in order for him to exist which she agrees. She is later joined by [[Manga/KOn Yui Hirasawa]], [[Manga/YuGiOh Téa Gardner]], [[{{Manga/Hamtaro}} Oxnards]], [[Anime/MagicalGirlLyricalNanohaAs Shamal]], [[VideoGame/GaistCrusher Jinta Atō]], [[Anime/AquarionEvol MIX]], [[Manga/MagicKnightRayearth Mokona]] and [[Anime/SuitePrettyCure Kanade Minamino]] as Yui tries to keep their existence a secret and keep them out of trouble. Joining Yui is a transfer student named [[Anime/RinneNoLagrange Madoka Kyono]] and her partner Cocotamas [[Manga/ToLoveRu Haruna Sairenji]], [[Anime/MacrossFrontier Sheryl Nome]] and [[Anime/YuriKumaArashi Kumacaron]].
* ''LightNovel/{{Kampfer}}'': [[Manga/HighSchoolOfTheDead Rei Miyamoto]] is an ordinary high schooler who finds out she can turn into [[Anime/TengenToppaGurrenLagann Yoko]]. She fights other people with her friends Anime/CuteyHoney, [[Franchise/LyricalNanoha Nanoha]], and [[Series/ICarly Carly]].
* ''Anime/KazemakaseTsukikageRan'': [[Manga/FruitsBasket Saki Hanajima]] is a [[HardDrinkingPartyGirl Sake loving]] female {{ronin}} who is joined by martial artist [[Manga/OnePiece Nami.]]
* ''Manga/KenichiTheMightiestDisciple'': In order to become stronger, [[Anime/MobileFighterGGundam Domon Kasshu]] trains with [[Manga/ChronoCrusade Rosette Christopher]], [[Anime/ErgoProxy Hoody]], [[Manga/OnePiece Arlong]], [[Anime/MazingerZ Koji Kabuto]], [[Anime/TheBigO Alex Rosewater]], [[Manga/MaisonIkkoku Yusaku Godai]] and [[Anime/HellGirl Ai Enma]].
* ''Anime/KikisDeliveryService'': [[Manga/DetectiveConan Conan Edogawa]] and his cat [[Manga/RanmaOneHalf Shampoo]] move to a seaside town to practice magic.
* ''Manga/KimiNiTodoke'': [[Anime/HellGirl Ai Enma]] is a socially awkward girl that resembles a horror movie character ,but that doesn't stop her and [[LightNovel/FateZero Waver Velvet]] from falling in love.
* ''Manga/{{Kinnikuman}}'': [[Film/ANewHope Luke Skywalker]] is a bungling superhero who learns that he is a prince from outer space.
* ''LightNovel/KinosJourney'': [[Literature/BattleRoyale Shiori Kitano]] and her talking motorcycle move from town to town having adventures and solving problems.
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%% ''Kiss X Sis'' was removed from the wiki for violating the content policy.
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* ''Manga/KissHimNotMe'': After drastically losing weight YaoiFanGirl [[Manga/SayonaraZetsubouSensei Kaere Kimura]] gains the attention of [[UnwantedHarem several male classmates]] such as [[Anime/{{Free}} Haruka Nanase]], [[LightNovel/{{Another}} Manabu Maejima]], and [[LightNovel/SwordArtOnline Kirito]]; who she'd rather [[ShipperOnDeck ship with]] than be with. [[LightNovel/{{Durarara}} Celty Sturluson]] is a {{Bifauxnen}} and fellow Fujoshi.
* ''Manga/KOn'': [[ShugoChara Su]], [[LightNovel/AsuraCryin Aine Shizuma]], [[VisualNovel/UminekoWhenTheyCry Satan]] and [[VideoGame/FinalFantasyXIII Serah Farron]] join a light music club. [[Anime/MagicalGirlLyricalNanoha Vita]] is their teacher, and [[LightNovel/{{Oreimo}} Kirino Kousaka]] later joins the gang.
* ''LightNovel/KonoSubarashiiSekaiNiShukufukuO'': After his ridiculous death, [[Anime/AquarionEvol Jin Muso]] meets the goddess [[Manga/AkameGaKill Akame]], who offers him the chance to be reborn in a world of adventures. Jim agrees but not before forcing Akame to come along with him. There, Jin and Akame form an adventurng party with [[LightNovel/UndefeatedBahamutChronicle Noct Leaflet]] and [[LightNovel/{{Oreshura}} Ai Fuyuumi]]. HilarityEnsues from then on.
* ''[[Anime/SamuraiPizzaCats Kyattou Ninden Teyandee]]'': Manga/InuYasha, [[Anime/TenchiMuyo Ryoko]] and [[Manga/OnePiece Arlong]] are feline ninja who fight an evil band of ninja crows led by [[Anime/CowboyBebop Spike Spiegel]] while working at a pizzeria.
* ''Anime/{{Kyousogiga}}'': [[LightNovel/ShakuganNoShana Shana]] went to Mirror Kyoto with [[Manga/DeathNote Near]] and [[Manga/HayateTheCombatButler Hayate Ayasaki]] where she meets [[Anime/MobileSuitGundamWing Trowa Barton]], [[Anime/BloodPlus Saya Otonashi]] and [[Anime/MobileSuitGundamSeedDestiny Shinn Asuka]], who are protectors of the city and waiting for their parents, [[Anime/CardcaptorSakura Cerberus]] and [[Anime/MobileSuitGundamSeed Athrun Zala]]. She also meets [[Anime/PuellaMagiMadokaMagica Homura Akemi]], and her assistant, [[Franchise/AceAttorney Miles Edgeworth]].

!!L
* ''Anime/LegendOfGalacticHeroes'' in the future, where mankind has expanded far beyond the confines of Earth and are in midst of war between two factions, [[Anime/DragonBallZ Vegeta]], a poor, but ambitious noble from the Galactic Empire, sets out to lead the Empire and unite the Universe under his rule. He is assisted mainly by his childhood friend and close subordinate [[TransformersVictory Wingwaver]], and his handpicked squad of talented commanders. Chief among them are his earliest followers [[Manga/AzumangaDaioh Chiyo's Dad]] and [[Anime/ScienceNinjaTeamGatchaman Ken The Eagle]]. Meanwhile, on the other side, [[Anime/UFORoboGrendizer Duke Fleed]] of the Free Planets Alliance, a gifted tactician and Vegeta's eventual WorthyOpponent, and is tasked with defending the Alliance along with fellow solders [[Anime/MobileSuitZetaGundam Jerrid Messa]], [[Anime/MobileSuitGundam Kai Shiden]], and later his adopted son [[Manga/{{Akira}} Tetsuo Shima]], among others.
* ''Anime/TheLegendOfKoizumi'' OVA: Former Japanese prime minister [[VideoGame/FinalFantasyVII Sephiroth]] delegates with Korean leader [[Manga/OnePiece Brook]] and his son [[Manga/GreatTeacherOnizuka Eikichi Onizuka]] [[MundaneMadeAwesome using mahjong.]] Later, Sephiroth delegates with Chinese leaders [[VideoGame/MetalGearSolid Liquid Snake]] and [[Manga/ZatchBell Dr. Riddles]], which takes a turn for the worse when Communist leader [[Manga/FistOfTheNorthStar Raoh]] is brought back from the dead.
* ''Anime/LesMiserablesShojoCosette'': [[Anime/{{Macross7}} Ray Lovelock]] is being chased down by [[JuOn Takeo Saeki]] and he adopts [[Anime/CodeGeass Empress Tianzi]] who later grows up as [[Anime/CodeGeass Nunnually vi Britannia]] and falls in love with [[LightNovel/ACertainMagicalIndex Motoharu Tsuchimikado]].
* ''Anime/ALittleSnowFairySugar'': Orderly 11-year-old [[Manga/OnePiece Marguerite]] has her plans turned upside-down by a little fairy named [[Anime/KidouTenshiAngelicLayer Madoka Fujisaki]], who has the power to make snow. They are soon joined by wind fairy apprentice [[Anime/MakaiSenkiDisgaea Laharl]] and sun fairy apprentice [[Manga/GunslingerGirl Emilio]], and all of them have taken up residence in her home, where she lives with her grandmother [[Manga/DetectiveConan Takako Inubushi]]. Part of the problem is that she's the only human around who can see and hear them. The three need to find a "twinkle" in order to become full-fledged season fairies of their respective types, but they cannot find out what it is, and indeed, have different ideas of what it's like... not to mention that Elder [[Anime/DigimonFrontier Cerberumon]] isn't helping much, especially given his fixation on the romantic pursuit of full-fledged rain fairy [[Anime/ExcelSaga Excel]], who in turn, seems to have an interest in cloud fairy [[TransformersAnimated Waspinator]], who just wants to make the perfect cloud. Mixed up in all this craziness are Marguerite's friends [[Manga/InuYasha Chiyo]] and [[Anime/FutariWaPrettyCureSplashStar Kayo Ando]], inventor [[Manga/KOn Sawako Yamanaka]], and RichBitch and self-proclaimed rival [[Manga/{{Aria}} President Aria]].
* ''Anime/LostUniverse'': [[{{Manga/Saiyuki}} Goku]] and his SpaceshipGirl [[Anime/SaberMarionetteJ Lime]] roam the galaxy fighting evildoers, one of whom happens to be [[{{LightNovel/Slayers}} Gourry Gabriev]].
* ''Manga/LoveHina'': [[Anime/{{Pokemon}} Takeshi]] lives with his CoolBigSis aunt [[LightNovel/{{Slayers}} Lina Inverse]], and is surrounded by hot chicks such as [[Anime/UltraManiac Ayu]], [[VideoGame/MegaManX Lumine]], [[LightNovel/FullMetalPanic Kaname]], [[Manga/AzumangaDaioh Sakaki]], [[Anime/CodeGeass Rakshata]] and [[Manga/{{Bleach}} Hiyori]].
* ''Anime/LuckyStar'': [[Manga/ZettaiKarenChildren Kaoru Akashi]], [[WesternAnimation/MyLittlePonyFriendshipIsMagic Fluttershy]], [[Manga/{{Saki}} Koromo]] and [[Anime/MacrossFrontier Sheryl Nome]] indulge in [[ProudToBeAGeek nerdy pursuits]]. [[Anime/FutureDiary Kamado Ueshita]] and [[Manga/{{Nichijou}} Sakamoto]] star in a low-budget TV show that airs between episodes.
** In the drama CD, the girls were [[VisualNovel/{{Clannad}} Kyou Fujibayashi, Nagisa Furukawa]], [[Anime/CodeGeass Kallen]], and [[Manga/BokuraGaIta Masafumi "Take" Takeuchi]].
* ''Anime/LupinIII'': [[Manga/DoctorSlump Dr. Mashirito]], [[Manga/DeathNote Watari]], Anime/CaptainHarlock & [[Anime/CuteyHoney Honey Kisaragi]] are a quartet of thieves that constantly get chased by a pissed off [[Series/KamenRiderBlackRX Grand Lord Crisis]].
** Except for that one time when [[Manga/DragonBall Piccolo]], [[Manga/{{Cyborg 009}} 005]], [[Anime/{{Dancougar}} Ryo Shiba]] & [[Manga/BlackLagoon Balalaika]] assumed their identities, attended a wedding between Ryo & [[Manga/DragonBall Chi Chi]] and get caught up in a treasure hunt. All the while, [[Franchise/TransformersGeneration1 Megatron]] is after their asses.

!!M
* ''[[Anime/SpeedRacer Mach GoGoGo]]'': [[Anime/MobileSuitGundam Garma]] races cars while [[WesternAnimation/TheSimpsons Bart Simpson]] and [[Manga/HunterXHunter Zeno Zoldyck]] sneak in the back. Anime/MayaTheBee is Garma's girlfriend.
* ''Anime/{{Macross}}'':
** ''Anime/SuperDimensionFortressMacross'': Young civilian pilot [[Anime/SuperDimensionCavalrySouthernCross Bowie Emerson]] [[note]][[Anime/SailorMoonCrystal Tuxedo Mask]] [[TheOtherDarrin in most media released after]] his tragic AuthorExistenceFailure[[/note]] become comes to Macross Island upon the requests of his mentor [[Manga/DetectiveConan Kogoro Mouri]] to see the launch of the SDF-1 Macross, captained by [[WesternAnimation/StarWarsTheCloneWars Count Dooku]], however Bowie is forced into combat when aliens, lead by [[Manga/FistOfTheNorthStar Devil Rebirth]], attack Macross Island. Bowie, however he also has to deal with a love triangle between [[CelebrityVoiceActor a pop singer]] and bridge officer [[Anime/NeonGenesisEvangelion Naoko Akagi]].
* ''Anime/{{Madlax}}'': Legendary mercenary [[Anime/YuGiOhGX Asuka Tenjoin]] and [[RichBitch wealthy]] heir [[TheTwelveKingdoms Princess Shoukei]], two females who have little memory of their pasts, team up and investigate [[WesternAnimation/TheAngryBeavers Norbert]], who's taken interest to them.
* ''Anime/MagicalGirlLyricalNanoha'': [[VideoGame/Disgaea2CursedMemories Rozalin]] attempts to befriend [[VideoGame/EndlessFrontier Neige Hausen]] who is suffering from her mad mother [[WesternAnimation/JusticeLeague Hawkgirl]].
** ''Anime/MagicalGirlLyricalNanohaAs'': [[VideoGame/BlazBlue Rachel Alucard]] found out a sealed book which contains a sealed [[Franchise/AceAttorney Franziska von Karma]], along with her guardians [[Anime/DiGiCharat Dejiko]], [[VideoGame/SuperRobotWarsAdvance Lamia Loveless]], [[VideoGame/TalesOfDestiny Reala]] and [[VideoGame/SamuraiShodown Asura]]. Rozalin and Neige try to befriend them.
** ''Anime/MagicalGirlLyricalNanohaStrikers'': Rozalin, Neige and Rachel formed a squadron consisting [[VideoGame/BlazBlue Taokaka]], [[Anime/MusouKakyouASummerDaysDream Reimu Hakurei]], [[CrossdressingVoices shota version of]] [[Anime/TengenToppaGurrenLagann Yoko Littner]] and [[VideoGame/ArcanaHeart Heart Aino]]. They stumble upon ''[[VideoGame/TalesOfLegendia Norma Beatty]]'' and has to protect her from the forces of WesternAnimation/JohnnyBravo.
* ''Anime/MagicalPrincessMinkyMomo'': [[Manga/DrSlump Arale]] undergoes a MagicalGirlQueenlinessTest.
* ''Manga/MahouSenseiNegima'': [[LightNovel/ACertainMagicalIndex Mikoto Misaka]] teaches a class consisting of *huff* [[VisualNovel/{{Clannad}} Ryou Fujibayashi]], [[Anime/CodeGeass Cornelia li Britannia]], [[Manga/AzumangaDaioh Osaka]], [[VideoGame/CastlevaniaTheDraculaXChronicles Marie Renard]], [[Manga/{{Beelzebub}} Hilda]], [[Manga/SayonaraZetsubouSensei Kafuka Fuura]], [[Franchise/StreetFighter Sakura Kasugano]], [[Manga/FruitsBasket Tohru Honda]], [[Manga/{{Monster}} Nina Fortner]], [[Anime/MariaHolic Mariya Shidou]], [[LightNovel/HaruhiSuzumiya Ryoko Asakura]], and [[LoadsAndLoadsOfCharacters that's only the more crucial characters]]!!!
* ''Manga/MaidSama'': [[Anime/SquidGirl Eiko Aizawa]] is the student council president of a formerly all-boys' school, but has a part time job as a maid at a cafe run by [[LightNovel/OokamiSan Otohime]]. She may or may not be falling in love with [[VisualNovel/ShukufukuNoCampanella Leicester Maycraft]].
* ''Anime/MaiHiME'': [[Anime/KaleidoStar May Wong]], [[Anime/CodeGeass Nina Einstein]] and [[Anime/MagicalGirlLyricalNanoha Suzuka Tsukimura]] are among a dozen girls sent to school to fight shadowy demons...a school run by [[spoiler:three-hundred-and-]]eleven-year-old [[LightNovel/FullMetalPanic Tessa Testarossa]]. [[Anime/NeonGenesisEvangelion Kaworu Nagisa]] sticks around to [[HiddenAgendaVillain watch the chaos unfold]].
* ''Anime/MaiOtome'': [[Manga/XXXHolic Mokona]] enrolls in a MagicalGirlWarrior academy, but her powers can only activate with the help of [[spoiler:fake]] princess [[Anime/CodeGeass C.C.]]. [[LightNovel/SpiceAndWolf Holo the Wise Wolf]] is Mokona's #1 rival, and the adopted daughter of [[Anime/TengenToppaGurrenLagann Kamina]], who is working under the strict orders of the tyrannical [[Anime/MobileSuitGundamSEED Athrun Zala]]. [[Manga/AzumangaDaioh Yomi]], the school's #2 student, [[GreenEyedMonster is jealous of]] Mokona and Holo to a homicidal degree (''especially'' Mokona).
* ''Anime/MariaHolic'': [[Anime/DiGiCharat Dejiko]] moves to an All-Girls Catholic School due to her dislike of men and thinks she met the perfect girl in the form of [[VisualNovel/SteinsGate Ruka Urushibara]]...unfortunately for her, Ruka is actually a CreepyCrossdresser who has switched identities with his [[HalfIdenticalTwins Half Identical Twin]] Sister [[Anime/DeathNote Misa Amane]] as part of a bet to see who will win chairmanship of the school, and his maid [[Anime/SayonaraZetsubouSensei Chiri Kitsu]] is the only other person in on it.
* ''Marvel Disk Wars - The Avengers'': Although he now suffers from cancer, [[Manga/JoJosBizarreAdventure Dio Brando]] is now [[Film/Deadpool2016 near-invulnerable, moderately crazy, a superlative (if unorthodox) martial artist and swordsman, always carrying at least two guns and, terrifyingly, is capable of tearing the fourth wall asunder.]]
* ''Manga/MariaSamaGaMiteru'': [[VisualNovel/FateStayNight Rin Tohsaka]], [[Manga/DragonBallZ Android 18]], [[VisualNovel/DanganRonpa Junko Enoshima]], [[Anime/HellGirl Ai Enma]], [[Manga/{{Beelzebub}} Hilda]], [[Manga/{{Claymore}} Ophelia]], and others attend an all-girls Catholic school, SchoolgirlLesbian hijinks [[BaitAndSwitchLesbians may or may not ensue]].
* ''Anime/MazingerZ'': [[Anime/GoLion Emperor Daibazzal]], a megalomanaical MadScientist, sends his henchman who is half [[Manga/{{Devilman}} Silene]] and half [[Manga/FullmetalAlchemist King Bradley]] with an army of [[MonsterOfTheWeek mechanical monsters]] to wreak havoc. The only one who can stop them is [[KenichiTheMightiestDisciple Apachai Hopachai]] piloting a giant robot invented by his late grandfather. Joining him are [[Manga/{{Kinnikuman}} Alexandria Meat]] whose [[{{Fembot}} robot]] fires breast missles and [[Anime/DairuggerXV Kazuto Nagano]] who gets his own robot.
* ''Manga/MidoriDays'': [[Anime/TengenToppaGurrenLagann Kittan]] is a tough fighter who just wants to have a girlfriend. Without any explanation, his right hand becomes [[Anime/MaiHime Mai Tokiha]].
* ''Manga/MinamiKe'': [[Manga/MahouSenseiNegima Negi Springfield]], [[Anime/MagicalGirlLyricalNanoha Erio Mondial]], and [[VisualNovel/UminekoWhenTheyCry Sakutaro]] are siblings and are engaging [[SliceOfLife normal lives]].
* ''Manga/{{Mnemosyne}}'': Private investigator [[Anime/HellGirl Ai Enma]] and her assitant [[LightNovel/ShakuganNoShana Shana]] happen to be an immortal couple.
* ''Manga/MonthlyGirlsNozakiKun'': [[Manga/DailyLifeWithMonsterGirl Papi]]'s crush [[VideoGame/BlazBlue Hazama]] turns out to be a renowned [[ShoujoDemographic Shoujo manga]] artist and becomes his assistant along with [[LightNovel/ACertainMagicalIndex Accelerator]]. Also starring {{Tsundere}} [[TheAce popular girl]] [[Franchise/DanganRonpa Touko Fukawa]] and {{Bifauxnen}} [[VisualNovel/{{Clannad}} Nagisa Furukawa]]. [[ShowWithinAShow The manga]] they're making has [[Anime/TheIdolmasterCinderellaGirls Nana Abe]] and [[Manga/DeathNote Light Yagami]] as their main characters
* ''Anime/{{Monster}}'': [[WesternAnimation/CorpseBride Victor Van Dort]] saves [[Anime/CardCaptorSakura Eriol Hiiragizawa]] who turns out to be a mass murderer, and decides to fix the mistake. Eriol's long lost twin sister is [[VisualNovel/{{Clannad}} Kotomi Ichinose]].
* ''Anime/MyNeighborTotoro'': [[Anime/RanmaOneHalf Akane Tendo]] and [[Manga/FushigiYuugi Nuriko]] have strange and wonderful adventures when they move to the country with their dad, the mastermind who brought you [[VideoGame/{{Earthbound}} Giygas]]. Said mastermind's wife is [[Anime/LuckyStar Kanata Izumi]].
* ''Literature/MayaTheBee'': [[{{Manga/SpeedRacer}} Francine]] is a female bee who is friends with [[{{Anime/DragonBall}} Son Goku]] and [[{{Manga/DevilMan}} Alphonse]]
* ''Manga/MyLoveStory'': GentleGiant [[Anime/PokemonOrigins Blue]] is in love with [[VideoGame/TheLastOfUs Ellie]], but she seems to already be in love with the very {{Bishonen}} [[Anime/{{Free}} Haruka Nanase]].
* ''Manga/MysteriousGirlfriendX'' has [[Manga/TsubasaReservoirChronicle Syaoran]] being addicted to [[NewMeat someone else's]] [[{{Fetish}} drool]], who gets hit on by [[Manga/MyBrideIsAMermaid NaGARsumi]]; his older sister who have just graduated from [[LightNovel/ACertainMagicalIndex a certain Maid Academy]], and then [[VisualNovel/{{Clannad}} Kyou Fujibayashi]] hooking up with [[LightNovel/RoKyuBu Subaru Hasegawa]]. Yeah.
* ''Anime/MusouKakyouASummerDaysDream'': It's springtime in Gensokyo, and [[VideoGame/TheKingOfFighters Nakoruru]] is preparing for the annual feast. But something is amiss, as she soon finds out her donation box has been stolen! And it's not just there, either; the Scarlet Devil Mansion (When [[VideoGame/ArcanaHeart Eko]], [[WesternAnimation/AdventureTime Princess Bubblegum]] and [[Anime/QueensBlade Nowa]] lives) and its library have been robbed as well. With the help of [[WesternAnimation/TheSecretLifeOfPets Gidget]] and [[Film/TerminatorGenisys Sarah Connor]], can Nakoruru get to the bottom of this incident before the feast is ruined?
** In the second episode, someone stole the watermelons from CuteGhostGirl [[VideoGame/SenranKagura Yomi]] and her servant, [[VideoGame/SonicBoom Sticks the Jungle Badger]]'s house and now it's up to Sticks to recover them. Two moon rabbits, [[VideoGame/SenranKagura Hibari]] and [[Anime/QueensBlade Lamica]] are involved in the whole mess when doing an errant from her master [[Anime/{{Another}} Mei Misaki]] and her servant [[Film/TheHungerGames Johanna Mason]].

!!N
* ''Anime/NajicaBlitzTactics'': [[Anime/MobileSuitGundamWing Sally Poe]] is an undercover secret agent who's day job is a perfume worker. While on a mission, she encounters [[Manga/SgtFrog Sumomo]], a highly advanced android. Gratuitous amounts of {{Fanservice}} ensure.
* ''Manga/{{Nana}}'': Two strangers with the same first name and contrasting personalities perky college student-to-be [[Anime/{{Pokemon}} May/Haruka]] and cool, aloof rocker [[VideoGame/Persona4 Naoto Shirogane]] meet on a train and move out to Tokyo to find new purpose in their lives, forming an OddFriendship in the process.
* ''Manga/{{Naruto}}'': [[Manga/HighSchoolOfTheDead Rika Minami]], [[VideoGame/NoMoreHeroes Bad Girl]] and [[Manga/AxisPowersHetalia England]] are three ninja in training under [[Anime/DarkerThanBlack November 11]] in order to become master shinobi. At the end of the seres, [[spoiler: England does a HeelFaceTurn and joins [[Manga/{{Gintama}} Otose]] in order to kill his brother, [[VideoGame/FinalFantasyX Auron]]. Bad Girl decides to train under [[Anime/{{Gunbuster}} Reiko Kashiwara]] in order to get stronger. And Rika leaves the village to train with [[Franchise/KingdomHearts Xigbar]].]]
** ''Manga/{{Naruto}} Shippuden'': After training with Xigbar for three years, Rika returns and, with new comrades like [[LightNovel/TheFamiliarOfZero Saito]] and [[Manga/SoulEater Lord Death]], she searches for her friend England. She is also being persued by a sinister organization led by [[VideoGame/MetalGearSolid2 Raiden]], [[spoiler: who is really working for [[Manga/GetterRobo Hayato Jin]] who is disguised as [[Manga/{{Hellsing}} Jan Valentine]]. Also, Rika later finds out that her parents are [[StreetFighter Ryu]] and [[Anime/SailorMoon Sailor Jupiter]].]]
** Later in the series, Rika trains with [[Anime/GaoGaiGar Geki Hyuuma]] to try and gain control of her SuperpoweredEvilSide, [[{{Transformers}} Optimus Prime]].
* ''Anime/NeonGenesisEvangelion'': Three unstable teens--shy [[Anime/CardcaptorSakura Yukito Tsukishiro]], brash [[{{Manga/Berserk}} Casca]], and seemingly emotionless [[LightNovel/{{Slayers}} Lina Inverse]]--are forced by ruthless leader [[Manga/OnePiece Don Krieg]] to battle "Angels" while under the command of Anime/SailorMoon. [[spoiler: One of said "Angels" turns out to be [[Manga/{{Naruto}} Gaara]] and Lina turns out to be a clone of Yukito's [[OedipusComplex mother]] [[Anime/CowboyBebop Faye Valentine]] and has the DNA of another Angel]].
** ''Anime/RebuildOfEvangelion'': Mostly the same except they're now joined by [[VideoGame/Persona3 Aegis]].
* ''Manga/{{Nichijou}}'': [[VisualNovel/SteinsGateZero Katsumi Nakase]],[[Anime/FutureDiary Minene Uryuu]], and [[Anime/DateALive Origami Tobiichi]] live [[BlatantLies completely normal lives]] in a class taught by ChildProdigy [[Manga/LuckyStar Akira Kogami]], with her robot [[LightNovel/{{Another}} Matsuko Arita]] and talking cat [[RelationshipVoiceActor Minoru Shiraishi]]. Other classmates include [[LightNovel/ACertainMagicalIndex Pierce Aogami]],[[Manga/DeadmanWonderland Kyoko Kasuga]], and [[Anime/CuteHighEarthDefenseClubLove Yumoto Hakone]].
* ''Literature/NightOnTheGalacticRailroad'': [[Manga/DragonBall Krillin]] and [[VideoGame/ApeEscape Specter]] go on a [[MindScrew surreal]], existential trip.
* ''Anime/NightRaid1931'': [[Anime/MobileSuitGundam00 Allelujah Haptism]], [[Manga/{{Bleach}} Ulquiorra Cifer]], [[Anime/GunXSword Van]] and [[Anime/YuriKumaArashi Lulu Yurigasaki]] are super-powered spies working for the ImperialJapan in 1930's Shanghai. [[Manga/OnePiece Sanji]] is the long-lost brother of Lulu and Allelujah's girlfriend is [[VisualNovel/FateStayNight Saber]].
* ''Anime/{{Nightwalker}}'': VampireDetective [[Anime/MobileFighterGGundam George De Sand]] is joined by agent [[Anime/SailorMoon Makoto Kino]], GirlFriday [[Manga/OuranHighSchoolHostClub Haruhi Fujioka]] and imp [[WesternAnimation/{{Animaniacs}} Dot Warner]].
* ''LightNovel/NogizakaHarukaNoHimitsu'': [[VisualNovel/{{Tsukihime}} Arcueid's]] brother and [[Manga/LoveHina Kaolla Su's]] friend is a [[Manga/AhMyGoddess real estate agent]] who has to protect a secret of crossdressing [[Anime/{{Monster}} Johan Liebert]], who once won a piano contest against [[Manga/MahouSenseiNegima Negi Springfield]]. [[Anime/MobileSuitGundam00 Nena Trinity]] is also involved. This won't end well...
* ''Anime/{{Noir}}'': Professional assassin [[Anime/RevolutionaryGirlUtena Juri Arisugawa]] and an amnesiac [[Anime/GunXSword Wendy Garret]] get tangled with organized crime and international conspiracies as they discover more about each other's pasts.
* ''Manga/NotariMatsutarou'': [[Film/XMenApocalypse Apocalypse]] is a scumbag trouble-making student who is in love with his teacher [[Anime/TenchiMuyo Mihoshi]].
* ''Manga/NoMatterHowILookAtItItsYouGuysFaultImNotPopular'': [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rainbow Dash]], a deranged and anti-social shut-in, desperately tries to find ways to become popular. Her brother is [[VisualNovel/{{Clannad}} Tomoya Okazaki]] and her "slutty" best friend is [[Anime/DeadmanWonderland Shiro]].

!!O
* ''Anime/OjamajoDoremi'': [[LightNovel/SisterPrincess Hinako]], a clumsy and hyper elementary school student, becomes a witch apprentice after discovering that [[WesternAnimation/InvaderZim Zim]] is a witch. After her best friends, brainy [[Manga/ZatchBell Suzume Mizuno]] and athletic Osakan transfer student [[LightNovel/HaruhiSuzumiya Tsuruya]] find out her secret, they become witch apprentices, too. They also recieve their own fairies: Hinako gets clumsy [[Anime/DigimonAdventure Tailmon]], Suzume gets kindhearted [[Series/BoyMeetsWorld Angela Moore]], and Tsuruya gets tough [[HeathcliffAndTheCatilacCats Riff-Raff]]. Later joining the team is Hinako's little sister, [[Manga/HighSchoolGirls Ikue Ogawa]]. They gain a rival witch apprentice, [[Manga/HanaYoriDango Sakurako Sanjo]], under the apprenticeship of Zim's rival, but later joins the team. A later addition to the girls is Japanese-American transfer student [[Anime/DemashitaPowerpuffGirlsZ Rolling Bubbles]]. The girls have to take care of a baby from the witch world as well, [[VideoGame/FireEmblemAwakening Nowi]], who uses magic to age up into an eleven-year-old.
** This isn't the only time Tsuruya would be [[Manga/AzumangaDaioh associated with Osaka]].
* ''Manga/OnePiece'':
** [[Manga/DragonBall Krillin]] starts his own pirate crew, recruiting swordsman [[VideoGame/SengokuBasara Date Masamune]], navigator [[Anime/{{Pokemon}} Saturn]], sniper [[WesternAnimation/SouthPark Kyle Broflovski]], chef [[Anime/TigerAndBunny Wild Tiger]], doctor [[Anime/{{Pokemon}} Pikachu]], archaeologist [[Anime/NeonGenesisEvangelion Ritsuko Akagi]], shipwright [[Manga/FullmetalAlchemist Yoki]] and musician [[Manga/TheLegendOfKoizumi Kim Jong-il]]. Eventually [[spoiler:they are split up by [[Anime/DragonBallZ Captain Ginyu]] and Krillin must save his brother [[UruseiYatsura Ataru Moroboshi]] from being executed.]]
** Furthermore it's revealed that Krillin's father is [[Manga/FullmetalAlchemist King Bradley]]; his followers include [[Manga/DragonBall Yamcha]] ([[Manga/{{Naruto}} Naruto]], as a kid) and [[Manga/{{Inuyasha}} Kagome Higurashi]].
** In an "abandoned" island, Krillin's crew meets MadScientist [[Manga/DragonBall Frieza]] and his assistant [[Manga/DeathNote Naomi Misora]]. There, they form an alliance with [[Manga/AttackOnTitan Levi]].
* ''LightNovel/{{Oreimo}}'': [[Manga/FullMetalAlchemist Greed]] can't believe that his sister [[LightNovel/DateALive Kotori Itsuka]] can be this cute and perverted.
* ''Manga/OsomatsuKun'':
** 1966 series: [[Manga/SazaeSan Sazae]] is the clueless leader of a group of sextuplets, with stern [[Anime/{{Yatterman}} Boyacky]][[note]]As well as every ''Anime/TimeBokan'' SmartGuy to date[[/note]] as their father.
** 1988 series: [[{{Manga/YuGiOh}} Ryou Bakura]], [[Anime/CrayonShinChan Toru Kazama]], [[Anime/{{Pokemon}} Ash Ketchum]], [[Anime/DetectiveConan Sonoko Suzuki]], [[Anime/Macross7 Ivane Geperuniti]], and [[LightNovel/{{Slayers}} Lina Inverse]] are all related. Their collective rival is none other than homeless, oden-loving [[Franchise/OnePiece Monkey D. Luffy]].
* ''Anime/OsomatsuSan'': Years later the sextuplets become [[VideoGame/FinalFantasyVII Cloud Strife]], [[{{VisualNovel/Clannad}} Tomoya Okazaki]], [[{{Anime/Durarara}} Izaya Orihara]], [[Anime/XxxHolic Kimihiro Watanuki]], [[Anime/BlackButler Sebastian Michaelis]], and [[VideoGame/KingdomHearts Sora]].
* ''VisualNovel/OtomeWaBokuNiKoishiteru'': After his grandfather passes away, [[VisualNovel/LittleBusters Riki Naoe]] infiltrates an all-girls school in drag in order to become eligible for chairmanship of it ([[ExcusePlot just go with it]]) where he falls for [[Anime/{{Shimoneta}} Anna Nishikinomiya]], [[Anime/IkkiTousen Hakufu Sonsaku]], [[VisualNovel/UminekoWhenTheyCry Mammon]], [[VisualNovel/{{Clannad}} Ryou Fujibayashi]], [[VideoGame/BlazBlue Litchi Faye-Ling]], and [[LightNovel/HaruhiSuzumiya Mikuru Asahina]].
* ''Manga/OuranHighSchoolHostClub'': As punishment for breaking an expensive vase, [[Anime/TheVisionOfEscaflowne Hitomi Kanzaki]] is forced to join [[Anime/SoulEater Death the Kid's]] "Pretty Boys" club to earn her keep. Members of said club include twincestous brothers [[Manga/TrinityBlood Pope Alessandro XVIII]] and [[VisualNovel/{{Tsukihime}} Shiki Tohno]], Vice President [[Manga/DeathNote Mikami Teru]], boy Lolita [[Manga/FruitsBasket Momiji Sohma]] and his stoic companion [[VisualNovel/{{Utawarerumono}} Orobo]], as well as their manager, [[VisualNovel/RumblingHearts Mayu Tamano]].

!!P
* ''Anime/{{Paprika}}'': [[Anime/{{Pokemon}} Musashi]] and [[Franchise/GhostInTheShell Batou]] try to figure who stole a dream-seeing device built by [[Anime/SailorMoon Tuxedo Mask]] ([[spoiler: It's [[Anime/TokyoGodfathers Gin]] and his lackey [[Manga/RanmaOneHalf Ryoga Hibiki]]!]]), with the help of Musashi's alter-ego, a perky red-headed [[Anime/NeonGenesisEvangelion Rei Ayanami]].
* ''Anime/PantyAndStockingWithGarterbelt'': LoveableSexManiac [[Manga/{{Heroman}} Holly Jones]] and ElegantGothicLolita [[LightNovel/{{Durarara}} Mika Harima]] are two angels sent to battle ghosts (including spectral Chihuahua [[Manga/{{Bleach}} Nanao Ise]]) under the command of [[Anime/GaoGaiGar Kotaro Taiga]]. They are later helped out by [[LightNovel/{{Baccano}} Firo Prochainezo]] who has a crush on Holly, and later fight two demon sisters, [[Anime/FreshPrettyCure Cure Passion]] and [[Manga/LetterBee Niche]], and their boss, [[WesternAnimation/MyLittlePonyFriendshipIsMagic Discord.]]
* ''Anime/ParanoiaAgent'': [[Manga/{{Monster}} Anna Liebert]], best known for creating [[Manga/NurseWitchKomugi Komugi]], is bludgeoned by a bat-wielding [[LightNovel/{{Baccano}} Jacuzzi Splot]]. [[Manga/DragonBallZ Nappa]] and [[Anime/KillLaKill Senketsu]] are sent to investigate the attacks.
* ''Anime/{{Pokemon}}'': [[Anime/YuGiOh Ryou Bakura]] goes on a journey to become a Pokémon master, with [[VideoGame/MegaManLegends Tron Bonne]] and [[Manga/LoveHina Keitaro Urashima]] providing support. Constantly they're hounded by [[LightNovel/{{Slayers}} Lina Inverse]], [[Manga/FullmetalAlchemist Roy Mustang]], and [[Manga/ShamanKing Manta Oyamada]] who are constantly trying to steal [[Manga/OnePiece Tony Tony Chopper]]. An egg later hatches for Tron Bonne, revealing [[WesternAnimation/ThunderCats2011 Snarf]]. Keitaro takes a break during season 2, and [[Anime/PrettyCure Mepple]] fills in.\\\
Eventually, Tron Bonne is replaced by [[Manga/{{Nana}} Nana "Hatchi" Komatsu]] and [[HelloKitty Pekkle]]. In turn, they are eventually replaced by [[Manga/BlackLagoon Revy]]. Then they and Keitaro are replaced by [[Anime/PuellaMagiMadokaMagica Madoka Kaname]] and [[Anime/SoulEater Death the Kid]]. Madoka and Death the Kid are then replaced by [[Manga/AttackOnTitan Eren Yeager]], his little sister [[Anime/YesPrettyCure5 Urara Kasugano]], and [[Anime/CardfightVanguard Yuri Usui]], a childhood acquaintance of Bakura.
* ''Anime/PokemonOrigins'': Manga/{{Naruto}} and [[LightNovel/ReZero Julius Euclius]] start their Pokémon journey when they receive their Pokémon from Anime/SpeedRacer. On their journey they become stronger by battling Gym Leaders like [[LightNovel/HaruhiSuzumiya Kyon]] as Naruto gets involved in taking down the nefarious Team Rocket run by [[Manga/SoulEater Lord Death]].
* ''Manga/ThePrinceOfTennis'': [[Manga/PandoraHearts Oz Vessalius]] joins the Seigaku tennis club led by [[VideoGame/MegaManX Zero]]. Also in the team are his sempai and constant companion [[Manga/{{Trigun}} Vash]], prodigy [[Manga/HunterXHunter Kurapika]], AwesomeByAnalysis [[Anime/YuGiOh Seto Kaiba]], {{Keet}} and doubles genius [[Anime/DigimonTamers Impmon]] and grumpy [[Manga/HajimeNoIppo Ippo]].
* ''Franchise/PrettyCure''
** ''Anime/FutariWaPrettyCure'': [[Anime/MobileSuitGundam00 Sumeragi Lee Noriega]] and [[Anime/CodeGeass C.C.]] are two MagicalGirls who fight the forces of evil. Later on, they're joined by [[Manga/{{Chobits}} Chii]].
** ''Anime/YesPrettyCure5'': [[Anime/EurekaSeven Renton Thurston]] gets distracted by a butterfly and bumps into [[Anime/DragonBallZ Trunks.]] He then uses the power of dreams to turn into a MagicalGirl. With his best friend [[Anime/DigimonFrontier Takuya]], [[Anime/PantyAndStockingWithGarterbelt Anarchy Stocking,]] [[Anime/CuteyHoney Honey Kisaragi]], and [[Anime/DigimonAdventure Mimi]], Renton is tasked with collecting 55 pixie creatures in order to restore Trunks, [[Manga/GunslingerGirl Triela]], and [[Anime/BirdyTheMighty Tstutomu's]] homeworld.
*** ''Yes! Precure 5 GO!GO!'': The team is joined by AloofAlly [[Manga/FutureDiary Tsubaki Kasugano]], who is really Triela, and [[Manga/FullmetalAlchemist Edward Elric.]]
** ''Anime/HeartCatchPrettyCure'': Shy flower girl [[Anime/SenkiZesshouSymphogear Tsubasa Kazanari]] gets to be "The Weakest MagicalGirl Ever" and work her ass off to become competent in fighting monsters under [[VideoGame/SoulSeries Zasalamel]] and his 'daughter' [[VideoGame/KidIcarusUprising Pit]], along with QuirkyMinibossSquad [[FateExtra Francis Drake]], [[VideoGame/SamuraiWarriors Ishida Mitsunari]] and [[Series/KaizokuSentaiGokaiger Warz Gils]], working under [[Anime/SaintSeiyaOmega Pegasus Kouga]] to prevent them to turn the world into desert, also helped with her [[TheFashionista fashionista]] [[Anime/RomeoXJuliet Juliet]], WholesomeCrossdresser student council president [[VideoGame/SuperRobotWarsDestiny Cliana Rimskaya]] and the legendary former MagicalGirl BroughtDownToNormal [[VideoGame/TalesOfVesperia Judith]].
** ''Anime/SuitePrettyCure'': Frequently fighting friends [[Anime/CodeGeass Kallen]] and [[Manga/{{Bleach}} Rukia]] become MagicalGirls tasked with helping [[Anime/ExcelSaga Excel]] collect musical notes before [[Anime/{{Pokemon}} Dawn]] can steal them.
* ''Manga/PrincessJellyfish'': [[VisualNovel/SuperDanganRonpa2 Chiaki Nanami]] lives in an all-female dorm with [[Manga/DeathNote Rem]], [[Manga/LovelyComplex Risa Koizumi]], [[Manga/{{Chobits}} Sumomo]], and [[Anime/HellGirl Ai Enma]]; when one day she meets WholesomeCrossdresser [[WesternAnimation/StevenUniverse Garnet]].
* ''Anime/PsychoPass'': Manga/{{Kobato}} joins the police force which is composed of [[LightNovel/FateZero Gilgamesh, Ryuunosuke Uryuu]], [[Anime/DGrayMan Lenalee Lee]] and [[LightNovel/{{Baccano}} Szilard Quates]] and led by [[Anime/BloodC Fumito Nanahara]].
* ''Anime/PuellaMagiMadokaMagica'': [[Anime/{{Pokemon}} Iris]] and her friend [[Manga/HighschoolOfTheDead Saya Takagi]] are approached by [[Anime/LuckyStar Kagami Hiiragi]], who offers to grant them each one wish in return for making them {{magical girl}}s. [[Manga/SgtFrog Natsumi Hinata]], [[VideoGame/TheLegendOfZeldaOcarinaOfTime Navi]], and [[Manga/MahouSenseiNegima Konoka Konoe]] are also major characters. [[spoiler:Navi gets eaten horribly, AndThereWasMuchRejoicing among ''Zelda'' fans.]]
** ''Anime/PuellaMagiMadokaMagicaTheMovieRebellion'': In what seems to be a happier iteration of the world, the five girls plus strangely familiar TeamPet [[Franchise/{{Neptunia}} Blanc]] defend Mitakihara from creatures known as Nightmares. It comes to a head when Iris and Saya's friend [[Manga/SayonaraZetsubouSensei Nami Hito]] continues to be rebuffed by her boyfriend, [[VisualNovel/UminekoWhenTheyCry Belphegor]], and spawns a Nightmare herself. But wait Natsumi feels like there's something ''wrong'', and is determined to figure out what's truly going on.

!!Q
* ''Anime/QueensBlade'': [[VisualNovel/FateStayNight Saber]], [[Manga/NyanKoi Nyamses]], [[Manga/{{Freezing}} Satellizer El Bridget]], [[LightNovel/HyakkaRyouranSamuraiGirls Sanada Yukimura]], [[AgarestSenki Routier]], [[ShugoChara Amu Hinamori]], [[Anime/{{Grenadier}} Rushuna Tendo]], [[Anime/PuellaMagiMadokaMagica Sayaka Miki]], [[Anime/MagicalGirlLyricalNanoha Vivio Takamachi]], [[VideoGame/{{Utawarerumono}} Eruru]], [[Manga/SugarSugarRune Waffle]], [[VideoGame/ValkyriaChronicles Selveria Bles]], [[Anime/MobileSuitGundamUnicorn Marida Cruz]] and [[Anime/MobileSuitGundamSeed Lacus Clyne]] battle it out to see who would become [[ThereCanOnlyBeOne the next queen.]] ''Seikon No Qwaser's'' Ekaterina "Katja" Kurae is the one who foresees the match.

!!R
* ''Manga/RanmaOneHalf'': [[Manga/DeathNote L]] is an expert martial artist who turns into [[{{LightNovel/Slayers}} Lina Inverse]] when splashed with water. [[Manga/DeathNote Near]] is a tsundere. They are thrown into an arranged marriage by their fathers ([[Anime/KirbyOfTheStars King Dedede]] and [[Anime/{{Macross7}} Exsedol Folmo]], respectively). They aren't too keen about this, and neither are their various suitors (which include [[Anime/YuGiOhGX Yubel]], [[Anime/CowboyBebop Spike Speigel]], [[Anime/{{Pokemon}} Giovanni]], and [[LightNovel/DirtyPair Yuri]]).
* ''Anime/RanpoKitanGameOfLaplace'': [[Anime/MatanteiLokiRagnarok (Adult) Loki]], [[Anime/DokiDokiPrecure Cure Ace]] and [[Anime/SailorMoonCrystal Gurio Umino]] solve mysteries and [[TheyFightCrime fight crime]]!
* ''Anime/RevolutionaryGirlUtena'': [[Anime/ElfenLied Mariko]], a tomboyish girl whose goal is to be a prince, must defend Rose Bride [[Anime/AhMyGoddess Megumi Morisato]] which means dueling the Student Council consisting of [[Manga/JoJosBizarreAdventure Dio Brando]], [[Manga/DragonBallZ Trunks]], Manga/SailorMoon, and [[Manga/CardCaptorSakura Kero]]. Dio's sister [[LightNovel/HaruhiSuzumiya Emiri Kimidori]] wants to [[BrotherSisterIncest screw him]]
* ''Anime/RingingBell'': After [[Manga/CandyCandy Candy White]]'s mother is killed by [[WesternAnimation/TransformersGenerationOne Megatron]] she seeks revenge...and then is taken under his wing and grows up into [[Manga/FistOfTheNorthStar Kenshiro]]. Narrated by [[Franchise/StarWars Yoda]].
* ''Manga/RosarioToVampire'': [[Manga/DetroitMetalCity Souichi Negishi]], due to a mix-up, is sent to a school for supernatural beings. He falls in love with [[Anime/MagicalGirlLyricalNanoha Fate Testarossa]], although other students (such as [[Manga/ToLoveRu Golden Darkness]], [[Manga/DoujinWork Sora Kitano]], and [[Manga/FullmetalAlchemist Alphonse Elric]]) also want to jump his bones.
* ''Manga/RozenMaiden'': [[Anime/FutureDiary Reisuke Houjou]] is a shut-in whose main companion is a [[LivingToys living doll]] named [[VideoGame/Persona3 Elizabeth]]. Elizabeth and several other dolls - [[Manga/AzumangaDaioh Kaorin]], [[LightNovel/HaruhiSuzumiya Asakura]], [[Anime/{{Claymore}} Claudia]], and [[Manga/{{Chobits}} Chii]] - make Reisuke's life an even bigger living hell in their [[ThereCanBeOnlyOne battle for the right to become the "perfect girl"]].
** ''Rozen Maiden: Zurückspulen'': In a parallel universe, Reisuke refuses to participate in the Alice Game and grows up to become [[Manga/TheDevilIsAPartTimer Sadao Maou]] where he receives the same offer.
* ''Manga/RurouniKenshin'': [[Anime/LeChevalierdEon Mary Shallot]], a samurai who has sworn never to kill again, ends up crashing in the residence of [[Anime/StreetFighterIITheAnimatedMovie Chun Li]], a young kendo practitioner. He also befriends martial artist [[Manga/LoveHina Keitaro Urashima]], KidSamurai [[Manga/FruitsBasket Ritsu Sohma]] and master medic [[Manga/AirMaster Kaori Sakiyama]].
!!S
* ''Anime/SaberMarionetteJ'': On a planet populated by men, [[Anime/RevolutionaryGirlUtena Wakaba Shinohara]], a poor but hard-working young man, finds himself with three [[RobotGirl female androids]]: GenkiGirl [[Anime/RanmaOneHalf female Ranma]], YamatoNadeshiko [[Manga/MahouSenseiNegima Sayo Aisaka]] and [[Manga/AzumangaDaioh Yukari Tanizaki]].
* ''Manga/{{Saki}}'': [[Manga/HayateTheCombatButler Hayate]], [[Anime/TengenToppaGurrenLagann Boota]], [[Anime/CodeGeass Lelouch, Kallen]], [[LightNovel/ShakuganNoShana Shana]] & [[VisualNovel/FateStayNight Rin]] get together and play {{Mahjong}}.
* ''Manga/SakuraDiaries'': High School Graduate [[Anime/CodeGeass Kaname Ohgi]] seeks to enter a prestigious university but ends up in a triangle between classy beauty [[Manga/FullmetalAlchemist Martel]] and his cute cousin [[Anime/WitchHunterRobin Yurika Dojima]].
* ''Manga/SaintSeiya'': [[Anime/SailorMoon Tuxedo Kamen]], [[Anime/MobileSuitGundam Bright Noa]], [[Manga/SilentMoebius Robert Device]], [[Manga/DetectiveConan Heiji Hattori]] and [[Anime/MobileFighterGGundam Schwartz Bruder]] are young warriors who fight for [[Anime/SailorMoon Luna]], who happens to be the incarnation of the goddess Athena.
** ''Anime/SaintSeiyaOmega'': The incarnation of goddess Athena is kidnapped by [[Anime/MazingerZ male Baron Ashura]], and thus it is up to [[VideoGame/SuperRobotWars Masaki Andoh]], [[Anime/TengenToppaGurrenLagann Kamina]], [[Manga/{{Bleach}} Yoruichi Shihouin]], [[VideoGame/BlazBlue Jin Kisaragi]] and [[VideoGame/Disgaea4APromiseUnforgotten Valvatorez]], alongside the lone wolf [[VisualNovel/FateStayNight Archer]] to rescue her.
* ''{{Manga/Saiyuki}}'': Literature/JourneyToTheWest, featuring a {{Jerkass}} [[Anime/MobileSuitGundamWing Duo Maxwell]], {{Keet}} [[Anime/MobileSuitGundamSEED Kira Yamato]], TeamMom [[VideoGame/DissidiaFinalFantasy Kuja]] and ChivalrousPervert [[Manga/OnePiece Sanji]], ordered by an ambiguously good [[Anime/MagicalGirlLyricalNanoha Precia Testarossa]] to retrieve an artifact stolen by [[VisualNovel/FateStayNight Caster]]. Barring their way is a group of {{Punch Clock Villain}}s consisting of NobleDemon [[VideoGame/GuiltyGear Ky Kiske]], little [[VideoGame/SengokuBasara Itsuki]], YamatoNadeshiko [[Anime/SailorMoon Hotaru Tomoe]], and BigBrotherMentor [[Manga/JoJosBizarreAdventure Jotaro Kujo]].
* ''Anime/SamuraiChamploo'': [[VisualNovel/FateStayNight Saber]] manages to trick [[Manga/OnePiece Roronoa Zoro]] and [[Franchise/KingdomHearts Saix]] into becoming her bodyguards in order to find a mysterious samurai.
* ''Anime/SayonaraZetsubouSensei'': [[VisualNovel/FateStayNight Shinji Matou]] is the suicidal [[WackyHomeroom homeroom]] teacher of [[PuellaMagiMadokaMagica Kyoko Sakura]], [[Anime/AttackOnTitan Armin Arlett]], [[LightNovel/HaruhiSuzumiya Mikuru Asahina]], [[Anime/DiGiCharat Dejikko]], [[{{Anime/Durarara}} Celty Sturluson]], [[Anime/MariaHolic Mariya Shidou]], and [[LoadsAndLoadsOfCharacters several other]] [[DysfunctionJunction basket cases]].
* ''Manga/SazaeSan'': (Using the most recent cast members) [[Anime/SallyTheWitch Yoshiko]] is married to [[Manga/DragonBall Master Roshi]] and has a child named [[VisualNovel/SuperDanganRonpa2 Usami]]. She also lives with her siblings [[Manga/FruitsBasket Ritsu Sohma]] and Manga/AstroBoy, and parents [[Manga/{{Berserk}} Ubik]] and [[Anime/SamuraiChamploo Ogin]].
** Now for [[TheOtherDarrin the Other Darrins]]: Roshi used to be [[Series/TheMuppetShow Scooter]], Ritsu was Manga/{{Doraemon}} and [[Film/ETTheExtraTerrestrial ET]], Astro Boy was [[ComicStrip/{{Peanuts}} Violet]] and Anime/MayaTheBee, Ubik was [[Franchise/StarWars Yoda]], and Ogin was [[VisualNovel/{{Clannad}} Shino Okazaki]].
* ''Anime/ScienceNinjaTeamGatchaman'': Earth is threatened by the Galactor terrorist organization, who plots to steal the world's natural resources and eventually become its sole ruler. In response, [[Franchise/StarWars Darth Vader]] of the International Science Origination deploys the Science Ninja Team as the counteroffensive, led by the heroic [[Anime/SailorMoon Nephrite]] and consisting of [[Film/KamenRiderZO Doctor Mochizuki]], rebellious 2nd in command, [[Anime/{{Pokemon}} Celebi]], the sole female, [[Anime/SpaceRunawayIdeon Cosmo Yuki]], Celebi's adopted kid brother, and country boy [[TheBigGuy Big Guy]] [[Manga/MaisonIkkoku Ibuki Yagami's Dad]].
* ''Manga/SgtFrog'': [[Manga/{{Inuyasha}} Shippo]] plots to take over the earth after landing in the home of [[Anime/PuellaMagiMadokaMagica Homura Akemi]] and [[Anime/RevolutionaryGirlUtena Utena Tenjou]] (and fails epically), joined by [[Anime/YoKaiWatch Jibanyan]], [[Manga/{{Hellsing}} Alucard]], [[Manga/JoJosBizarreAdventure Dio Brando]], and [[Manga/DragonBallZ Trunks]] along the way.
* ''Anime/SeitokaiYakuindomo'': [[VisualNovel/DaCapo Yoshiyuki Sakurai]] recently enrolled in a new high school, Ousai Academy, because it was an easier commute. From the very first day he gets pressganged into the Student Council, which is chaired by [[VisualNovel/UminekoWhenTheyCry Satan]]. Assisting her are [[Anime/HellGirl a girl possessed by the Hell Girl]] and [[Manga/{{Karin}} Karin Maaka]], a genius returnee with an IQ of 180 who speaks fluent English and can do ten-digit calculations. All they ever do is talk about sex.
* ''Anime/SenkiZesshouSymphogear'': [[Anime/PuellaMagiMadokaMagica Madoka Kaname]] gets drafted to fight [[VideoGame/{{Xenosaga}} Gnosis-like]] creatures, alongside a broken [[Franchise/LyricalNanoha Fate Testarossa]], who didn't accept that Madoka got her powers from her beloved DeadPartner [[Manga/RanmaOneHalf Nabiki Tendou]]. Their battles are observed by [[Manga/{{Naruto}} Itachi Uchiha]] and Madoka and Fate need to work together to stop [[LightNovel/SwordArtOnline Sinon]] and [[LightNovel/{{Durarara}} Erika Karisawa]] from doing evil things with said Gnosis-like creatures.
** ''Senki Zesshou Symphogear G'': After stopping the evil plans of Sinon and Erika, Madoka and Fate are now joined by Erika and now need to work together to stop [[Manga/KOn Mio Akiyama]], [[Franchise/LoveLive Eli Ayase]], [[Anime/GirlsUndPanzer Saori Takebe]], [[VideoGame/SenranKagura Ryouki]] and [[VideoGame/{{Blazblue}} Yuuki Terumi]] from using ancient technology to kill everyone.
** ''Senki Zesshou Symphogear GX'': Madoka, Fate and Erika, now joined by Mio, Eli and Saori, who've been taken in by Itachi's organisation now have to stop [[Manga/GochuumonWaUsagiDesuka Chino Kafuu]] and her 4 dolls, [[LightNovel/ChivalryOfAFailedKnight Stella Vermillion]], [[Anime/ValkyrieDriveMermaid Kasumi Shigure]], [[Anime/LittleWitchAcademia Sucy Manbavaran]] and [[VideoGame/SenranKagura Kafuru]].
* ''LightNovel/ShakuganNoShana'': [[WesternAnimation/KimPossible Ron Stoppable]] is walking in the street until he encounters FieryRedhead [[Manga/{{Gintama}} Kagura]] fighting a demon by chance. After the fated encounter, Kagura decided to attend Ron's school to observe him. Eventually she falls for him and forms a LoveTriangle with Ron's classmate [[Anime/OutlawStar Melfina]].
* ''Manga/ShamanKing'': [[Anime/{{Pokemon}} Nyarth]] is a ghost obssessed kid who befriends [[Anime/FullmetalAlchemist Lust]], a Shaman who is engaged to [[Manga/RanmaOneHalf Female Ranma]]. Together with Lust and his spirit companion [[Anime/TengenToppaGurrenLagann Kamina]], he goes on adventures with [[Manga/FullmetalAlchemist Edward Elric]], [[Anime/RurouniKenshin Sanosuke Sagara]] and later [[Manga/{{Hellsing}} Zorin Blitz]].
* ''Anime/ShinkonGattaiGodannar'': [[Franchise/AceAttorney Phoenix Wright]] marries the MUCH younger [[VisualNovel/{{CLANNAD}} Furukawa Nagisa]] and gets to fight a bunch of GiantSpaceFleaFromNowhere, assisted by a really busty [[VideoGame/CastlevaniaPortraitOfRuin Charlotte Aulin]], and occasionally gets interrupted/helped with a duet of loli [[Anime/MagicalGirlLyricalNanoha Signum]] and a gritty [[VideoGame/SengokuBasara Tokugawa Ieyasu]].
* ''Anime/ShirokumaCafe'': [[Anime/CodeGeass Lelouch]] is pressured by his mother, [[VideoGame/FinalFantasyVII Sephiroth]], to get a job. As a result he starts working at a cafe owned by [[Anime/TokyoGhoul Uta]] along with [[Anime/LuckyStar Miyuki Takara]]. [[{{Anime/Durarara}} Izaya Orihara]] is a frequent customer
* ''Manga/ShugoChara'': [[Manga/SoraNoManimani Mihoshi Akeno]] must battle TheHeartless by using the powers of [[Manga/HidamariSketch Yuno]], [[Anime/PrincessTutu Ahiru]] and [[Manga/KOn Yui Hirasawa]]. She also has a crush on [[Anime/MobileSuitGundam00 Graham Aker]], but her rival [[Franchise/LyricalNanoha Fate Testarossa]] won't let her have a word about that.
* ''VisualNovel/ShukufukuNoCampanella'': [[LightNovel/MayoiNekoOverrun Takumi Tsuzuki]] is a member of an adventurer's clan with [[LightNovel/ACertainMagicalIndex Komoe]]. [[Manga/{{NEEDLESS}} Solva]] and [[Manga/HidamariSketch Miyako]] join him on the night of a meteor show when Mimi Usa wakes up.
* ''Manga/SilentMobius'': [[Anime/MobileSuitGundamWing Dorothy Catalonia]], a sorceress of no small power, joins an [[AmazonBrigade all female police force]] consisting of [[HollywoodCyborg cyborg]] [[Manga/DragonBall Bulma]], {{Miko}} [[Anime/SoulEater Marie Mjolnir]], esper [[VideoGame/SakuraWars Orihime Soletta]] and hacker [[Anime/TsukuyomiMoonPhase Shizuru]], all of whom are under the command of [[Anime/OutlawStar "Hot Ice" Hilda]] in order to fight a race of extradimensional monsters.
* ''Manga/SketDance'': [[Anime/PantyAndStockingWithGarterbelt Brief]], [[Manga/HayateTheCombatButler Hayate Ayasaki]], and [[LightNovel/HaruhiSuzumiya Kyon]] create [[LightNovel/HaruhiSuzumiya another club]] to help out others.
* ''Manga/SkipBeat'': [[Anime/TengenToppaGurrenLagann Yoko]] is so in love with her childhood friend [[Anime/MobileSuitGundam00 Setsuna]], but when he became a celebrity, he dumps Yoko. With her feelings hurt, Yoko decided to become a celebrity that is bigger than Setsuna and joins the same talent agency of the country's biggest star and Setsuna's rival [[Manga/AyashiNoCeres Tooya]].
* ''Manga/SlamDunk'': [[Anime/DragonBallZ Trunks]] joins his school's basketball club to impress [[Manga/AzumangaDaioh Yukari Tanizaki]], but she has her eyes on another member of the team: [[Anime/CodeGeass Li Xingke]]. [[Manga/{{Bleach}} Tessai]], TheCaptain of the team, turns out to be Yukari's older brother, and he doesn't like Trunks that much. Other members of the team include vice captain [[VideoGame/MetalGearSolid Otacon]], point guard [[Anime/ScienceNinjaTeamGatchaman Jinpei]] and returning legendary junior high player [[Manga/DNAngel Dark Mousse]].
* ''LightNovel/{{Slayers}}'': Sorceress [[Anime/LostUniverse Canal Vorfeed]] and swordsman [[VideoGame/SuperRobotWarsOriginalGeneration Folka Albark]] team up for food and treasure. They are later joined by chimera [[VisualNovel/TriangleHeart3SweetSongsForever Kyouya]] [[Franchise/LyricalNanoha Takamachi]] and Princess [[Anime/YuGiOhGx Shou Marufuji]]. White Priestess [[Manga/AhMyGoddess Urd]] and Golden Dragon [[Manga/{{Inuyasha}} Sango]] once traveled with the group. Of course, they are all being manipulated by a mysterious demon priest known as [[Manga/{{Naruto}} Gaara of the Sand]].
* ''Manga/{{Softenni}}'': [[Manga/ShinryakuIkaMusume Sanae Nagatsuki]], [[VisualNovel/TheyAreMyNobleMasters Shinra Kuonji]], [[Anime/AngelBeats Yui]], [[Manga/ToLoveRu Haruna Sairenji]] and [[TransformersAnimated Sari Sumdac]] are a mostly incompetent middle school tennis team.
* ''Anime/SonicX'': [[VideoGame/FatalFrame Mafuyu Hinasaki]] is the king of speed, who, with help from [[Manga/DGrayMan Allen Walker]] helps fight off such guys as [[VideoGame/MetalGearSolid4GunsOfThePatriots Big Boss]] and [[Manga/BlackButler Lau]].
** Season 3: After [[Manga/{{Bleach}} Ichigo]] regresses back to Allen via inter-dimensional travel, the gang must help [[Anime/TenchiMuyo Ryo-Ohki]] defend the galaxy from the likes of [[Manga/{{Hellsing}} Alucard]].
* ''Anime/SoulEater'': [[Manga/NatsuNoArashi Jun]] and her human/weapon partner, [[Franchise/KingdomHearts Roxas]], battle against villians like the evil witch [[Manga/AzumangaDaioh Kagura]], and her insane [[AmbiguousGender daughter/son]], [[Anime/RebuildOfEvangelion Mari Illustrious]], with the aid of their friends, the cat witch [[Manga/LuckyStar Kagami]], [[Manga/FullmetalAlchemist Ling]], and [[Manga/LoveHina Sarah]]. Also, [[Anime/MobileSuitGundamSEED Mu La Flaga]] is a {{jerkass}} InfinityPlusOneSword.
* ''Manga/SoreGaSeiyuu'': [[LightNovel/ReZero Emilia]] is a shy, newcomer to voice acting. This series brought you to by [[LightNovel/ShakuganNoShana Yukari Hirai]].
* ''Anime/SpaceDandy'': [[VisualNovel/FateStayNight Archer]] is a dandy guy... in space! With the help of his [[CelebrityVoiceActor singer]] RobotBuddy and FunnyAnimal [[Anime/PantyAndStockingWithGarterbelt Brief]] - and occasionally helped by [[Manga/AzumangaDaioh Kagura]] - he aims to catalog rare alien species. But there's danger afoot [[Manga/DragonBallZ Mr. Satan]] - backed by [[Manga/FistOfTheNorthStar Souther]]- wants him dead. [[LightNovel/{{Durarara}} Izaya]] is a good friend of Archer who turns out to be the commander of the forces opposing Souther.
* ''Manga/SpecialA'': [[LightNovel/HaruhiSuzumiya Mikuru Asahina]] is [[FoeRomanceSubtext very obsessed]] with beating her childhood rival [[Anime/CodeGeass Lelouche vi Britania]].
* ''LightNovel/SpiceAndWolf'': [[VideoGame/DissidiaFinalFantasy The Onion Knight]] is a traveling merchant who comes across [[VideoGame/TheKingOfFighters Mai Shiranui]] one day. Together, they face the consuming evil of...'''''[[MundaneMadeAwesome economics.]]'''''
* ''Manga/SpiderRiders'': [[Anime/CardcaptorSakura Syaoran Li]] discovers another world, teams up with [[LightNovel/ScrappedPrincess Leopolde Scorpse]] the spider and fights alongside [[Anime/CodeGeass Nina Einstein]], [[Manga/SgtFrog Kururu]], [[Anime/LuckyStar Hiyori Tamura]] & [[Anime/BurstAngel Meg]] against the forces of [[Anime/{{Avenger}} Warrior Volk]], [[Anime/ElCazadorDeLaBruja Douglas Rosenberg]], [[Manga/LoveHina Motoko Aoyama]], [[Anime/DragonBallZ Garlic Jr]] and [[Anime/MobileSuitGundamWing Duo Maxwell]].
* ''Anime/SpiritedAway'': [[Anime/FromUpOnPoppyHill Sachiko Hirokoji]] witnesses her parents get turned into pigs and is forced to work with [[VideoGame/MetalGearSolid4GunsOfThePatriots EVA]]. Now she must work with [[Anime/{{Anohana}} Jinta]] to save her parents and escape the spirit world. She also gains help from [[Anime/XamdLostMemories Ishuu Benikawa]] and later EVA's son [[Anime/SummerWars Kenji Koiso]]. Other denizens of the spirit world include [[WesternAnimation/SamuraiJack Aku]], [[WesternAnimation/ThePrinceOfEgypt Pharaoh Seti I]], VideoGame/ProfessorLayton, [[Anime/HowlsMovingCastle Calcifer]], and [[Anime/EurekaSeven Matthieu]].
* ''Manga/StrawberryMarshmallow'': [[Manga/{{Bleach}} Ise Nanao]] unwillingly plays host to the antics of her [[TheGenericGuy plain]] younger sister [[Anime/MaiHime Natsuki Kuga]], and her friends [[Manga/{{Bleach}} Rukia Kuchiki]], [[Manga/SgtFrog Angol Mois]], and [[Manga/InitialD Natsuki Mogi]], a CuteClumsyGirl in glasses.
* ''Anime/StrikeWitches'': [[Manga/RosarioToVampire Kurumu Kurono]] is recruited by [[Anime/MaiHime Natsuki Kuga]] and [[Anime/MobileSuitGundamSEED Lacus Clyne]] to join a group of [[AmazonBrigade female pilots]] who fight aliens with powerful jet engines strapped to their legs...but [[PantyShot never wear pants]].
* ''Manga/SquidGirl'': [[Anime/SailorMoonCrystal Sailor Mercury]] emerges from the ocean with the intent of punishing humanity for polluting her home. She attempts to make a small beach hut restaurant, run by sisters [[Anime/PantyAndStockingWithGarterBelt Kneesocks]] and [[Manga/RozenMaiden Suigintou]], into her base of operations, but, after breaking a hole in the wall of it, she's forced by the two to work for them as a waitress. [[Anime/OsomatsuSan Karamatsu]] is one of the beach lifeguards, who has a rather obvious like for Suigintou. Mercury is frequently forced into fetishistic cosplay outfits by [[Manga/TheWorldGodOnlyKnows Elsie]].


!!T
* ''Anime/TanteiOperaMilkyHolmes'': [[WesternAnimation/MyLittlePonyFriendshipIsMagic Pinkie Pie, Applejack, Rarity and Rainbow Dash]] are a group of super-powered detectives who lose their powers at the beginning and go through various hijinks to get them back.
* ''Anime/TekkamanBlade'': [[VideoGame/SuperRobotWarsCompact2 Kyosuke Nanbu]] becomes an armored warrior-monster who'd invade Earth, but turns out to be rebelling and helps out the Earthling led by [[Anime/MobileSuitGundam Bright Noah]] and assisted with [[{{LightNovel/Slayers}} Gourry Gabriev]] and [[Anime/CowboyBebop Faye Valentine]] (he fell in love with Faye), reunite with his little sister [[VideoGame/SuperRobotWarsCompact2 Excellen Browning]], only to see her die in front of him and must fight his evil little brother [[VideoGame/SuperRobotWarsGaiden Shu Shirakawa]] and big brother [[VideoGame/SuperRobotWarsCompact2 Stern Neue Regisseur]], who spearheaded the monsters attacking humanity.
* ''Anime/TenchiMuyo'': [[Manga/AhMyGoddess Keiichi Morisato]] is told by his grandfather [[VideoGame/MegaMan Dr. Wily]] of a demon in a cave. Driven nuts by it, he enters it and accidentally awakens [[Anime/MobileSuitGundamWing Quatre]]. Her awakening catches the attention of [[Anime/PleaseTeacher Hatsuho Kazami]], who is brought to Earth with her sister [[VideoGame/SakuraWars Sakura Shinguji]]. Quatre's ship [[VideoGame/SonicAdventure2 Omochao]] is reborn just in time for [[VideoGame/SuperRobotWarsOriginalGeneration Excellen Browning]] to arrive. Soon, [[Anime/MobileSuitGundam0083StardustMemory Anaval Gato]] arrives, looking to claim a lot of power, only for Keiichi to defeat him and rescue [[Anime/OnePiece Nico Robin]] with his newfound powers.
* ''Anime/TengenToppaGurrenLagann'': [[VideoGame/BlazBlue Jin Kisaragi]] and his best friend [[Manga/AxisPowersHetalia America]] both pilot a giant robot and, with the help of [[LightNovel/{{Kampfer}} Senou Natsuru]], battle an army led by [[VideoGame/TheLegendOfZeldaOcarinaOfTime Link]]. He also falls in love with [[Manga/HighSchoolOfTheDead Marikawa Shizuka]].
* ''Anime/TenkaiKnights'': [[LightNovel/{{Baccano}} Czeslaw Mayer]], [[Manga/RozenMaiden Jun Sakurada]], and [[WesternAnimation/BatmanBeyond Matt McGinnis]] fight for the fate of another world against the evil [[WesternAnimation/TeenageMutantNinjaTurtles1987 Rocksteady]]. They're later joined by [[Anime/DeadmanWonderland Toto Sakigami]] and [[Disney/BigHero6 Go Go Tomago]].
* ''Manga/TenjhoTenge'': [[Anime/MobileSuitGundamSeed Kira Yamato]] and [[Anime/{{Pokemon}} Kojiro]] are two new students at Todo Academy. They join the Juken Club, a fighting club consisting of [[Anime/SailorMoon Ami Mizuno]], her younger sister [[LightNovel/HaruhiSuzumiya Yuki Nagato]], and [[Anime/MobileFighterGGundam Domon Kasshu]], who has a crush on Yuki.
* ''Anime/TigerAndBunny'': Aging superhero [[VideoGame/FinalFantasyVIII Laguna]] [[VideoGame/DissidiaFinalFantasy Loire]] is forced to team up with a younger superhero, [[LightNovel/{{Baccano}} Claire Stanfield]]. Some of the other superheroes are [[Anime/YuGiOh Seto Kaiba]], [[Anime/PantyAndStockingWithGarterbelt Stocking]], [[Manga/KOn Tsumugi Kotobuki]], [[LightNovel/ACertainMagicalIndex Accelerator]], and [[Manga/ThePrinceOfTennis Genichirou Sanada]].
* ''Anime/TokyoGodfathers'': Three homeless people rescue an abandoned baby named [[VisualNovel/{{Clannad}} Ushio]] one Christmas Eve, and go on a quest to find her mother [[Franchise/MetalGear Meryl]].
* ''Manga/ToLoveRu'': [[Anime/SoulEater Liz Thompson]] is an ordinary high school girl who accidentally molests alien [[Manga/{{Kannagi}} Nagi]] in her bathroom. {{Fanservice}} ensues. In the sequel series, assassin [[Anime/{{Pokemon}} Oshawott]] and Nagi's sister [[Manga/KOn Yui Hirasawa]] are given more time in the spotlight.
* ''LightNovel/{{Toradora}}'': The romantic journeys of the tough-looking but actually gentle [[VideoGame/FireEmblemPathOfRadiance Black Knight]] and the pint-sized, initially angry [[LightNovel/BludgeoningAngelDokuroChan Sabato]]. [[VisualNovel/ToHeart Multi]] and [[Anime/PuellaMagiMadokaMagica Sayaka Miki]] also compete for the Black Knight's feelings.
* ''Manga/{{Toriko}}'': [[VideoGame/MegaManClassic Proto Man]] is a food bounty hunter who wishes to create the ultimate meal. [[Manga/FullmetalAlchemist Edward Elric]] is his traveling partner.
* ''Anime/TrainingWithHinako'': [[VisualNovel/FateStayNight Illyasviel von Einzbern]] is an OtakuSurrogate that becomes an [[AnimatedActor anime girl]] after [[TrappedInTVLand entering through the TV]]...[[EsotericHappyEnding We are supposed to find this to be a good thing]].
* ''TransformersGenerationOne'' Anime:
** ''Anime/TransformersHeadmasters'': During their war, [[Anime/TheBigO Dan Dastun]] and [[Anime/OutlawStar Hazanko]] encounter [[Anime/DragonBallZ Captain Ginyu, Oolong]], Manga/{{Devilman}}, [[Manga/YoureUnderArrest Detective Tokuno]], [[Film/{{Transformers}} The Fallen]], Anime/SpeedRacer & [[Manga/GunsmithCats Jonathan Washington]]. After Dan dies, [[Anime/MazingerZ Koji Kabuto]] assumes leadership (akin to the 1986 movie). [[Anime/SailorMoon Zoisite]] and [[Anime/ArmoredTrooperVotoms Ru Shako]] (who also narrates) both fight each other, die and get rebuilt. WesternAnimation/{{Captain Planet|and the Planeteers}} also dies (at the hands of Jonathan, no less).
** ''Anime/TransformersSuperGodMasterforce'': A group of robots consisting of [[Anime/MobileSuitGundam Garma Zabi]], [[Anime/MobileSuitGundam0083StardustMemory Chap Adel]], [[Manga/DragonBall Man Wolf]] & [[Manga/KoiKaze Zensou Saeki]] recruit [[Anime/{{Dancougar}} Sara Yuki]], [[Manga/AhMyGoddess Urd]], [[Manga/DragonBall Chaozu]], [[Anime/RoninWarriors Rowen]], [[Anime/OutlawStar Harry MacDougall]], [[Manga/ArakawaUnderTheBridge Toru Shirai]], [[Manga/DetectiveConan Detective Shiratori]] and [[{{Manga/Saiyuki}} Kougaiji]] against the war between [[Anime/MazingerZ Baron Ashura's male side]], [[Manga/{{Mahoromatic}} Slash]] / [[Manga/GetterRobo Michiru]], [[Anime/ScienceNinjaTeamGatchaman Jinpei the Swallow]], his brother [[Anime/BubblegumCrisis Nigel Kirkland]], [[CrouchingMoronHiddenBadass Badass idiots]] [[Manga/{{Kinnikuman}} Robin Mask, Buffaloman & Detective Gobugari]] and rookies [[Anime/MobileSuitGundamZZ Mondo Agake]], Manga/CaptainTsubasa and [[Anime/SaintSeiya Aphrodite]].
** ''Anime/TransformersVictory'': [[VideoGame/{{F-Zero}} Captain Falcon]] leads his team of [[Anime/MobileSuitGundam0083StardustMemory Alpha Bate]], [[{{LightNovel/Slayers}} Dilgear]], [[Anime/MobileSuitZetaGundam Astonaige Medoz]], [[Anime/LegendOfGalacticHeroes Siegfried Kircheis]], [[Anime/BlueGender Tony Frost]]; mini-bots [[LightNovel/DirtyPair Kei]], [[Anime/SailorMoon Sailor Mercury]] & [[Anime/ShamanicPrincess Apoline]] and his adopted son (yes you read that right), in the war against [[VideoGame/MetalGearSolid Roy Campbell]] and his forces.
* ''Anime/TransformersRobotsInDisguise'': [[VideoGame/TheKingOfFighters Terry Bogard]], alongside his spiteful brother [[Anime/HeroicAge Mobead]], [[VideoGame/{{Medabots}} Joe Suihan]], [[LightNovel/AriaTheScarletAmmo Goki Muto]], Speedbreaker[[note]]who's obsessed over red cars, which [[Anime/PaniPoniDash Hibiki Watanuki]] just happens to drive[[/note]], construction vehicles [[Anime/CoyoteRagtimeShow May]], [[Manga/HunterXHunter Kuroro Lucifer]], [[WesternAnimation/TransformersPrime Dreadwing]] and [[Manga/{{NANA}} Shoji Endo]] and bullet trains [[Anime/DaiGuard Tomoyoshi Ishizuka]], [[Anime/RurouniKenshin Eiji Mishima]] & [[VideoGame/TalesOfVesperia Raven]], together with [[VisualNovel/ToHeart Shiho Nagaoka]] and [[Manga/HappyLesson Kisaragi Ninomai]]. Fights [[Anime/YuGiOh Akunamukanon]] and his minions [[Anime/ReadorDie Ikkyu]] the poet, bumbling idiots [[Anime/BeastWarsII DJ, Starscream]] & [[Manga/OnePiece Emporio Ivankov]], sub-commander [[Anime/TigerAndBunny Rock Bison]] and military vehicles [[Anime/RurouniKenshin Aritomo Yamagata]], [[Anime/FullmetalAlchemist Denny Brosh]], [[Anime/ShinkonGattaiGodannar Go Saruwatari]], [[Anime/BattleSpiritsShonenToppaBashin Kyoji Kawato]] & [[Anime/YuGiOh Step Johnny]], who combine to form [[Manga/ThePrinceOfTennis Bobby Max]].
* ''Anime/TransformersArmada'': Autobots [[Franchise/RatchetAndClank Clank]], [[Manga/FlameOfRecca Recca Hanabishi]] and [[GIJoe Zartan]] travel across the Earth to find tiny, human-sized robots before [[Manga/SorcererHunters Gateau Mocha]], [[VideoGame/{{Tekken}} Jin Kazama]], [[WesternAnimation/TransformersAnimated Prowl]] and [[Anime/WitchHunterRobin Nagira]]. Along the way, the 'bots are joined in their search by fellow team members [[Anime/SDGundamForce Bakunetsumaru]], [[Manga/AttackOnTitan Hannes]], [[Anime/HanbunNoTsukiGaNoboruSora Tsukasa Sekoguchi]], [[WesternAnimation/SupermanTheAnimatedSeries Darkseid]] and [[Anime/BurstAngel Hayao Ichimonji]] and children [[Manga/{{Bleach}} Rikichi]], [[Anime/RedGarden Kate Ashley]], [[Manga/LoveHina Sachiyo Matsumoto]], [[LightNovel/FateZero Kariya Mato]] and [[Manga/SilverSpoon Taro Beppu]]. While [[Anime/ErgoProxy Vincent Law]], [[{{Film/Transformers}} Robert Epps]], [[Anime/CodeGeass Suzaku Kururugi]] and former Autobot [[{{Manga/Gintama}} Kondou Isao]] join the Decepticons. Towards the end, [[Anime/RioRainbowGate Mr. Clark]] becomes a threat.
** ''Anime/TransformersEnergon'': After the defeat of [[Anime/BlackCat River Zastory]]. Autobots [[Anime/TengenToppaGurrenLagann Kamina]], [[Anime/GaoGaiGar Gai Shishio]], [[Anime/TransformersGo Jinbu]], [[Anime/{{Macross7}} Basara Nekki]] and [[Manga/{{Akira}} Kaneda]], together with reformed Decepticons [[Anime/{{Avenger}} Parn]] and [[Manga/BlueExorcist Renzo Shima]] and humans DaveTheBarbarian & [[Anime/{{Futakoi}} Yosuke]] now face the Terrorcons and their leader [[BeastWars Tarantulas]]. But before long, [[{{Manga/Gantz}} Akitoshi Okazaki]] is revived, takes back Parn and Renzo, gives them, the ghost of [[BeastWars Quickstrike]] and [[Anime/IronMan Ramon Zero]] new bodies, steals [[Anime/DigimonAdventure Etemon]] from Tarantulas, adds [[WesternAnimation/BeastMachines Nightscream]] and his younger brother [[Manga/ProjectARMS Ryou Takatsuki]] to his ranks and tries to bring River back to life. The 'Bots meanwhile, encounter and recruit commander [[VisualNovel/{{CLANNAD}} Akio Furukawa]], rookie [[Manga/SkullMan Hayato Minagami]], {{Film/Thor}}, [[Anime/ElCazadorDeLaBruja Douglas Rosenberg]], former security guard [[Manga/BlackButler Lau]], [[{{VideoGame/Aikatsu}} Johnny Beppu]], [[VideoGame/TalesOfSymphonia Lloyd Irving]] and [[Anime/KiddyGrade Sinistra]].
** ''Anime/TransformersCybertron'': [[{{WesternAnimation/Gargoyles}} Goliath]] and his team of Autobots - [[Manga/SchoolRumble Kazuya Tanaka]], [[Manga/TegamiBachi Dr. Thunderland Jr.]], [[Anime/DarkerThanBlack Yuusuke Saitou]], [[Film/TransformersRevengeOftheFallen Sideswipe]], [[Series/GreysAnatomy George O'Malley]], [[LightNovel/DemonKingDaimao Boichiro Yamato]] and [[WesternAnimation/TheTransformers Spike Witwicky]], with humans [[Anime/DigimonTamers Hirokazu Shiota]], [[{{Franchise/Angelique}} Miriam]], [[Manga/RozenMaiden Souseiseki]], [[Anime/RocketGirls Motoko Mihara]] and [[Anime/GhostHound Seiichi Suzuki]], battle [[Anime/ArgentoSoma Michael Heartland]], [[Anime/WolfsRain Darcia]] and [[Anime/{{Planetes}} Hachirota Hoshino]] for [[MacGuffin four "Planet Keys"]] that are needed to restore InspectorGadget back to life. During the quest, [[VisualNovel/GreenGreen Hikaru Ichibanboshi]], [[Anime/SpeedGrapher Nakano]], [[Manga/ShugoChara Miki]], [[Manga/BlackLagoon Benny]], [[Anime/MobileSuitGundamSEEDDestiny Parnell Jesek]], [[VideoGame/SuperRobotWarsOriginalGeneration Kirk Hamill]], [[WesternAnimation/ABugsLife Francis]], [[VideoGame/GodOfWar Hades]], [[Anime/DinoZaurs Shieldsaurus]] and [[LightNovel/FullMetalPanic Goddard]] align themselves with the Autobots. While [[Anime/ParanoiaAgent Masami Hirukawa]], his buddy [[Franchise/PiratesOfTheCaribbean Captain Jack Sparrow]], [[Anime/NinjaScroll Kikori]], [[Anime/SoulEater Sid Barett]], [[VideoGame/InazumaEleven Someoka Ryuugo]], [[Manga/MahouSenseiNegima Yue Ayase]], [[Manga/FairyTail Count Balsamico]], [[WesternAnimation/TeenTitans Red Star]] and [[Manga/CromartieHighSchool Noboru Yamaguchi]] side with the Decepticons. Both [[VideoGame/StreetFighterIV Akuma]] and [[Anime/DogDays General Godwin]] end up [[HeelFaceTurn changing sides]] at different points in the series.
* ''Anime/TransformersGo'': Two teams of robots (one consisting of [[Anime/RinneNoLagrange Moid]], [[Anime/AquarionEvol Andy W Hole]] and [[{{Anime/Bakugan}} Golem]], the other with [[Film/{{Gremlins}} Billy Peltzer]], [[{{VisualNovel/Clannad}} Youhei Sunohara]] and [[Anime/NagiAsuALullInTheSea Itaru Shiodome]]) with the help of [[LightNovel/CatPlanetCuties Ichika]] and [[LightNovel/BodaciousSpacePirates Marika Kato]], do battle against the recently reawakened [[VideoGame/NamcoXCapcom Bravoman]], [[Anime/BeastWarsII Bighorn]], [[WesternAnimation/XMenEvolution Cyclops]] and [[LightNovel/{{Baccano}} Dallas Genoard]] to stop them from reviving their master.
* ''Manga/{{Trigun}}'': [[Manga/AxisPowersHetalia France]] roams the land for his brother [[Anime/CardcaptorSakura Yoshiyuki Terada]]. He is followed by [[Manga/DragonBall Bulma]], [[Manga/{{Inuyasha}} Kagome Higurashi]], and [[Manga/{{Bleach}} Sousuke Aizen]].
* ''Manga/TsubasaReservoirChronicle'': [[Franchise/KingdomHearts Vanitas]] travels with [[VideoGame/DynastyWarriors Lu Bu]], [[Anime/{{Pokemon}} Lucario]], and [[Anime/MaiOtome Arika Yumemiya]] to regain [[Anime/AngelBeats Yusa's]] memories.

!!V
* ''Manga/VampireKnight'': [[Manga/LoveHina Naru Narusegawa]] and [[Manga/DeathNote Light Yagami]] are students whose duty is to keep the Day Class from finding out that the Night Class is composed of Vampires such as [[Manga/RosarioToVampire Tsukune Aono]],[[Anime/CodeGeass Lelouch Lamperouge]] and [[Manga/MahouSenseiNegima Ayaka Yukihiro]]. Eventually Naru realizes that she is a vampire herself.
* ''Manga/VampirePrincessMiyu'': (OAV): [[Anime/DragonBallZ Chi-Chi]] is a vampire [[OlderThanTheyLook girl]] who, alongside her servant [[Manga/SaintSeiya Aries Mu]], must hunt down a race of demons. She crosses paths with spiritualist [[Manga/BlackLagoon Balalaika]].
** (Tv Series): [[Anime/NeonGenesisEvangelion Maya Ibuki]], a vampire [[OlderThanTheyLook girl]], and her servant [[VisionOfEscaflowne Allen Schezar]] hunt down demons. Maya poses as a [[{{Joshikousei}} student]] and befriends GenkiGirl [[Manga/DaaDaaDaa Nanami Tenchi]], [[{{Bokukko}} Tomboy]] [[Anime/SerialExperimentsLain Reika]] and {{Bookworm}} [[Anime/PrincessNine Mao Daidouji]].
* ''Anime/{{Vandread}}'': Life really does stink for [[Manga/FullmetalAlchemist Solf J. Kimble]]. His co-workers [[LightNovel/FullMetalPanic Sôsuke Sagara]] and [[Anime/DiamondDaydreams Tezuk]] constantly tease Kimble. [[WesternAnimation/GravityFalls Dipper]] is Kimble's robotic friend.

!!W
* ''Anime/WandabaStyle'': [[Manga/RozenMaiden Souseiseki]], [[VisualNovel/{{Clannad}} Nagisa Furukawa]], [[Anime/PuellaMagiMadokaMagica Homura Akemi]], and [[VisualNovel/FateStayNight Rin Tohsaka]] are an idol group determined to be the first one to go to the moon, leading the project is [[VisualNovel/DanganRonpa Chihiro Fujisaki]].
* ''Manga/WeddingPeach'': Clumsy [[Anime/DiGiCharat Rabi~En~Rose]], well-mannered [[Anime/FutariWaPrettyCure Cure White]], and tomboyish [[WesternAnimation/KaBlam June]] are Love Angels with the mission to destroy senders of hate, such as the Devil World's queen, [[Franchise/KingdomHearts Daisy Duck]], [[Anime/DigimonAdventure Igamon]], and Anime/SailorMoon (Who later becomes good). [[Anime/OjamajoDoremi Yuki-Sensei]] joins the team later on, and [[WesternAnimation/{{Rugrats}} Tommy Pickles]] was a former devil who's now on the Angels' side.
* ''Anime/WeissKreuz'': [[Anime/MobileSuitGundamWing Zechs Marquise]], [[Anime/MobileSuitGundam00 Lockon Stratos]], [[Anime/MobileFighterGGundam Dommon Kashuu]] and [[Anime/MobileSuitGundamSEED Clotho Buer]] are assassins with dark and troubled pasts.
* ''Anime/WelcomeToTheNHK'': [[Anime/MawaruPenguindrum Sanetoshi Watase]] is a shut-in who believes that he's the victim of a conspiracy. His Otaku neighbour [[Anime/ParanoiaAgent Little Slugger]] and [[Manga/TsubasaReservoirChronicle Sakura]] (a girl claiming to be working for a charity project) try to pull Sanetoshi out of his rut. In time, Sanetoshi is drawn into an ultimately botched suicide pact by [[Anime/ElfenLied Lucy]], and, later, into a pyramid scheme by [[WesternAnimation/StevenUniverse Lapis Lazuli]].
* ''Anime/TheWonderfulWizardOfOz'': [[Manga/NausicaaOfTheValleyOfTheWind Nausicaa]] travels alongside [[Manga/{{Monster}} Otto Heckel]], [[Anime/CastleInTheSky Shalulu]], and [[Franchise/StarWars Yoda]] in search for [[Series/KyoryuSentaiZyuranger Great Satan]] while trying to avoid [[Disney/TheEmperorsNewGroove Yzma]]. [[Anime/DigimonTamers Guilmon]] is also a princess.
* ''Manga/{{Working}}'': [[LightNovel/MaoyuuMaouYuusha The Hero]] is recruited by a petite [[LightNovel/HaiyoreNyarkoSan Nyarlathotep]] to work as a waiter in the family restaurant Wagnaria, where he faces a diverse group of colleagues, including androphobic [[Anime/NightRaid1931 Feng Lan]], katana-wielding [[LightNovel/{{Toradora}} Ami Kawashima]], ex-delinquent manager [[Manga/SgtFrog Sergeant Keroro]], stoic chef [[Manga/MinamiKe Hosaka]], his fellow chef [[Manga/SayonaraZetsubouSensei Nozomu Itoshiki]] and later [[Anime/{{Canaan}} Jin the Taxi Driver]], who brought along with him [[VisualNovel/{{CLANNAD}} Kyou Fujibayashi]].
** The Hero's sisters are later revealed as well, namely [[Manga/{{Saki}} Mako]], [[LightNovel/TheDevilIsAPartTimer Emilia]], [[Manga/HayateTheCombatButler Hinagiku]] and [[Anime/SoltyRei Solty]].
* ''Manga/TheWorldGodOnlyKnows'': [[LightNovel/AsuraCryin Takuma Higuchi]] is a Dating Sim God who makes a deal with the devil to capture runaway spirits with [[LightNovel/CatPlanetCuties Eris]]. Said spirits include {{Meganekko}} IdolSinger [[Manga/TheDevilIsAPartTimer Chiho Sasaki]], [[ShrinkingViolet shy]] [[CuteBookworm bookworm]] [[Anime/AngelBeats Kanade Tachibana]], token normal [[LightNovel/HaiyoreNyarukoSan Nyaruko]], [[{{Ojou}} Hime]][[{{Tsundere}} dere]] [[Anime/PuellaMagiMadokaMagica Madoka Kaname]], and strict librarian committee president [[Manga/SayonaraZetsubouSensei Kafuka Fuura]].

!!X
* ''Manga/{{X1999}}''(TV version): [[Anime/MobileSuitGundamSEED Shinn Asuka]] returns to Tokyo and must decide the fate of the world whether he should save it or destroy it. His childhood friends, [[Anime/HellGirl Enma Ai]] and [[VisualNovel/FateStayNight Archer]], got involved in this situation.
** (Movie version}: [[Anime/MobileFighterGGundam Domon Kasshu]] returns to Tokyo and must decide the fate of the world whether he should save it or destroy it. His childhood friends, [[Anime/CardcaptorSakura Tomoyo]] and [[Anime/CodeGeass Jeremiah]], got involved in this situation.
* ''Anime/XMen'': After [[Manga/{{Naruto}} the 5th Mizukage]] dies (again), [[Anime/TheBigO Michael Seebach]] rounds up all of his mutant students, which include [[Manga/{{Inuyasha}} Naraku]], [[Anime/SoulEater Shinigami-sama]], [[Anime/SailorMoon Sailor Mercury]], and [[VideoGame/MetalGearSolid Otacon]], to go to Japan to find [[VisualNovel/HigurashiWhenTheyCry Rika Furude]].
* ''Manga/XxxHolic'': [[Anime/CodeGeass Lelouch]] stumbles in a mysterious shop owned by [[VisualNovel/UminekoWhenTheyCry Beatrice]] who can grant wishes unless there's a price.

!!Y
* ''[[Anime/RoninWarriors Yoroiden Samurai Troopers]]'': [[Anime/DragonBallZ Trunks]], [[Anime/TheBraveExpressMightGaine Might Gaine]], [[Manga/DeathNote Mello]], LightNovel/CrusherJoe and [[{{Manga/Berserk}} Corkus]] don samurai armor to save the world from [[Anime/MobileFighterGGundam Dahal Muhammad]] and his henchmen [[Anime/DeadLeaves 777]] ([[spoiler:who later does a HeelFaceturn]]), [[Manga/AhMyGoddess Ohtaki]], [[Anime/BloodPlus David]] & a [[BrainwashedAndcrazy brainwashed]] [[Anime/SailorMoon Sailor Neptune]].
* ''Anime/YoKaiWatch'': [[LightNovel/SwordArtOnline Asuna]] tries to quell with supernatural sightings of Yo-kai in her city with the help of her butler, [[VisualNovel/FateStayNight Gilgamesh]]. One of the Yo-kai she befriends is a cat named [[Manga/SgtFrog Tamama]].
* ''Manga/YoureUnderArrest'': [[Anime/SaberMarionetteJ Bloodberry]] & [[Anime/SailorMoon Princess Kakyuu]] are a police duo in a force that also includes Series/GossipGirl [[Anime/TenchiMuyo Ryo-Ohki]], GentleGiant [[Manga/DoctorSlump King Nikochan]], a transgendered [[Anime/OutlawStar Jim Hawking]], Princess Kakyuu's love intrest [[VisualNovel/FateStayNight Gilgamesh]] and chief [[Anime/TransformersHeadmasters Soundblaster]].
* ''Anime/YuGiOh1998'': [[Anime/SailorMoon Sailor Uranus]], a former pharaoh of Egypt, is reincarnated in the body of [[Anime/NeonGenesisEvangelion Shinji Ikari]], who solved her puzzle. Together with Shinji's friends [[Manga/{{Naruto}} The Fourth Hokage]], [[{{Anime/Bleach}} Byakuya Kuchiki]], [[VideoGame/FinalFantasyVII Yuffie Kisaragi]],[[Anime/CodeGeass CC]], and Shinji's rival [[VideoGame/SuperSmashBros Marth]] , they play various games (not just card games) against such villains as Marth's sister [[Anime/SuperBook Joy]], and [[Anime/SailorMoon Prince Sapphire]].
* ''[[Anime/YuGiOh Yu-Gi-Oh! Duel Monsters]]'': Mostly the same as the first, except ; [[Anime/FromUpOnPoppyHill Hiroshi Tachibana]], a former pharaoh of Egypt, is reincarnated in the body of a boy who solved his puzzle. Together with his friends [[Manga/AxisPowersHetalia Japan]], [[{{Anime/Anohana}} Poppo Hisakawa]], [[Anime/TheCatReturns Yuki]], and Shirō's rival [[Manga/KatekyoHitmanReborn Spanner]]) (CC is completely absent), they play children's card games. Japan has a romantic subplot with [[WesternAnimation/InvaderZim Gaz]]. All of the good guys join forces to ultimately take down Manga/OsomatsuKun[[TheOtherDarrin /]][[Anime/{{Pokemon}} Ash Ketchum]].
* ''Anime/YuGiOhGX'': The hero of this story (who eventually becomes [[Manga/KatekyoHitmanReborn Dino]]) goes to a special school on an island. His rival is WesternAnimation/SpongeBobSquarePants, who has a crush on [[VideoGames/IceClimber Nana]]. His teacher is [[Anime/RanmaOneHalf Ranma Saotome]].
* ''Anime/YuGiOh5Ds'': [[Manga/KatekyoHitmanReborn Lambo and Dino's]] old singing buddy is living in the derelict ruins of the previous series' city, and has created his own motorcycle to hunt down is old friend [[Anime/GunXSword Vahn]] (whose Dann of Thursday turned into a giant Donut) because he stole something from him. Later on he meets up with two of his old friends, a director for a live action ''Manga/BlackButler'', and a shogun from ''Manga/{{Gintama}}''.
* ''Anime/YuGiOhBondsBeyondTime'': Hiroshi, Dino, and [[AndZoidberg the third guy]] are brought together through the power of TimeTravel to take down [[WesternAnimation/TheSimpsonsMovie Bart Simpson]].
* ''Anime/YuriOnIce'': [[LightNovel/{{Durarara}} Mikado]] becomes a figure skater under the tutelage of his idol [[Manga/BlackButler The Undertaker]] along with [[Manga/SoulEater Soul]].
* ''Manga/YuruYuri'': [[Manga/AttackOnTitan Krista Lenz]], [[Anime/TheIdolmasterCinderellaGirls Kanako Mimura]], [[Anime/{{Pokemon}} Axew]], and [[Anime/SuitePrettyCure Cure Muse]] have a club where they...[[{{Iyashikei}} just have fun]].
* ''Manga/YuYuHakusho'': [[Anime/{{Monster}} Johan Liebert]], [[VideoGame/FinalFantasyVI Kefka]], [[VideoGame/DissidiaFinalFantasy Pallazo]], [[Anime/NeonGenesisEvangelion Shinji Ikari]] and [[Anime/GaoGaiGar Guy Shishioh]] are hired (conscripted) by [[Manga/OnePiece Monkey D. Luffy]] to bust some yokai ass.


!!Z
* ''Manga/ZettaiKarenChildren'': [[LightNovel/HaruhiSuzumiya Haruhi]], [[Manga/NatsuNoArashi Arashi]], and [[Manga/ToLoveRu Lala]] are a super powered fighting team led by [[Anime/{{Basquash}} Iceman Hotty]], trying to stop an evil organization led by [[Series/KamenRiderDenO Urataros]].
* ''Anime/ZoidsChaoticCentury'': [[VideoGame/MegaManBattleNetwork GyroMan]] discovers a pair of capsules which contain [[VideoGame/MegaManBattleNetwork SharkMan]] and Franchise/{{Kirby}}. They soon run into [[Franchise/KingdomHearts Axel]] and VideoGame/{{Klonoa}} who soon join them to stop the evil plans of [[Anime/MobileFighterGGundam Chibodee Crocket]]. Soon enough Gyro Man encounters a mysterious rival known only as [[Franchise/DotHack Tsukasa]].

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