- JoJo's Bizarre Adventure: Golden Wind: Trish Una, daughter of the part's Big Bad, has a Stand named Spice Girl, whose kiai happens to be "Wannabe".
- Agent X: Super mercenary Taskmaster apparently has EVERYTHING Spice Girls related, including their solo stuff.
Films - Animated
- Chicken Little: Abby and Runt are singing "Wannabe" on karaoke when Chicken Little calls them about the piece of the sky falling in his room.
- Bend It Like Beckham: "All I'm saying, is there's a reason Sporty Spice is the only one without a fella."
- Dog Days (2018): In an attempt to bond with Amelia, Grace plays "Wannabe" on her phone, and Kurt joins her in an impromptu dance party. Amelia says, "May I be excused?" and leaves.
- Muppets from Space: Rizzo has a "Mice Girls" poster.
- In Social Queue, Zoe wears a Spice Girls T-shirt.
- The Boys (2019): Billy passionately compares his team to the Spice Girls, stating that they are all rubbish separately but are great together.
- Lucifer (2016): Lucifer interrogates as suspects asking "tell me what you want, what you really, really want".
- One Tree Hill:
- Brooke Davis is stated to have a mug in the shape of Posh Spice’s head.
- Brooke, Peyton, Haley, Rachel, Bevin and Shelley spontaneously break into a dance routine to "Wannabe" during their last party as high school students; the scene then cuts away to Skills singing along to the lyrics before defending himself by noting that the song's catchy.
- Saturday Night Live: A sketch from the Season 46 finale, which depicts a 1998 episode of The Hollywood Squares, features Baby Spice (Anya Taylor-Joy) as one of the contestants. Fortunately, she's the only celebrity who doesn't get removed from the broadcast for the immoral things they've done since then.
- A Series of Unfortunate Events (2017): an exchange between Larry and Carmelita references their famous song.Larry: Just tell me what you want, what you really really want.
Carmelita: Oh, I'll tell you what I want, what I really really want. - Sports Night: In the first season episode "Intellectual Property", Dan finds out the network is being charged $2,500 because he sang "Happy Birthday" to Casey on the air.note Dan points out on his own birthday, Casey gave him Mallomars, and that even if the four remaining Spice Girls had served them to him while wearing hot pants, it still wouldn't have been worth $2,500.
- ''Doctor Who in "The Giggle" the Toymaker dances to their song "Spice Up You're Life" in order to try and intimidate UNIT.
- Amphibia: In "Ivy on the Run", during Anne's flashback, she sings "I'll tell you what I need, what I really, really need!" while banging on pots and pans.
- Pinky and the Brain: In "My Feldmans, My Friends", Pinky's response to Brain's usual question is "How will we get the Spice Girls into the paella?".
