Lisa is put on anti-depressants after reading Internet reports that Springfield will be a barren wasteland in 50 years. Meanwhile, Bart and Milhouse's friendship is, once again, strained, thanks to a girl named Jenny.

!! Tropes:

* BaitAndSwitch: At the end, Bart is seen offering someone flowers and asking for forgiveness. He was talking to [[spoiler:Milhouse]].
* MushroomSamba: Lisa starts seeing smiley faces everywhere once she's on the pills. It reaches the point where Marge catches Lisa almost ready to make out with an electric fan.
* PaperThinDisguise: Homer suspects ''Milhouse'' is "El Barto".