Quotes: Room 101

Interrogation Chamber IX was stained black with blood.
The Ordo Malleus possessed the best interrogation personnel and equipment in the Imperium, and each interrogation chamber had seen generations of psychological theories turned into practice.
Psychic surgery that placed a new, compliant personality inside a prisoner's head. Complex stress cascade scenarios that could convince a man the universe had ended and that his interrogators were gods. Total personality destruction that removed every facet of a person's mind except for the part that contained whatever the Malleus wanted to know.

It is not uncommon to see patients undergo permanent psychological trauma in the presence of the Sphere, before the nerve stapler has even been strapped into position. Its effect on the general consciousness of the culture is profound: husbands have seen wives go inside, and mothers their children. Dr. Xynan left the surface of the sphere semitranslucent for a reason. You can hear them in there; you can see them. It is a thing of terrible beauty.
Baron Klim, Sid Meierís Alpha Centauri, "The Music of the Spheres",