Superman: "Somehow? That's not very scientific."
Batman: "Frustrating, isn't it? Maybe next time I tell you how much I hate magic, you won't give me that look."
"That's impossible! It's completely unscientific! I just can't — I refuse to believe in it!"
— Stein Heigar, Infinite Ryvius
Mei Ling: "I can understand the clothes, but to change [Zelda's] skin and eye color? That must take some powerful magic."
Mei Ling: "Come on, Snake! Don't get all grumpy and talk about how unscientific it is."
— Super Smash Bros.. Brawl
"Genetic mutations I can accept. Heck, multi-national ninja gangs, too, for that matter. But reincarnation? I'm sorry, there's just no scientific basis for that."
—Donatello, Teenage Mutant Ninja Turtles IDW
Tieria: Just how the heck is THAT even physically possible!?
Kira: Well...that's Aquarion for you.
Tieria: That's not the type of answer that I'm looking for!
— Super Robot Wars Z2: Hakai-Hen
"Who are you? I mean, you're me, but I'm me too. How can there be two me's? It's not scientifically possible. You are not scientifically possible!"
"It's easy to shrug off psychic phenomena as being "unscientific," but assuming the person experiencing them isn't totally faking it, it's probably more scientific to consider such experiences in psychological or neuro-physiological terms. They could, for example, be considered the result of "naturally-occuring magnetic or electrical phenomena that affect the brain," or they could be analyzed as a type of "mass hypnosis," etc. It's unscientific to laugh off poorly understood phenomena instead of trying to analyze them."
— From Ghost in the Shell: Man-Machine Interface