* Subversion in ''ComicBook/{{Watchmen}}'': Rorschach considers himself the OnlySaneMan, but is batshit insane. In the end [[spoiler: it gets double subverted, and it turns out that he was probably right.]]
** Dr. Manhattan is an inversion--he's all but omniscient, but his irregular perception of the timeline causes him to seem insane (sociopathic, at the very least) to people with a regular linear perception of time.
** Both Nite Owls are probably the legitimate examples, especially the first one; they realise how messed all superheroes are, including themselves, but can't do anything about it. They're still the most level-headed capes in the book.
* Ironically the initial characterization of Franchise/TheDCU's ComicBook/PlasticMan, who was a straight man (with somewhat goofy powers) in a world full of total nutbars. Every incarnation of him since has made ''him'' a total nutbar instead.
* Basically the entire point of ''{{normalman}}'', where norm is the only, um, normal man on a planet full of violent superhumans who quite literally get off on crazy "action scenes". The fact that he's a DeadpanSnarker indicates how well he takes his situation.
* In ''TwistedToyfareTheater'', Spider-Man is basically the only person in the entire world with a single lick of common sense. However, this has caused him to become so [[JadeColoredGlasses jaded]] he flat-out refuses to participate in any kind of action if he can avoid it, for example immediately taking the blue pill to go back to sleep when Morpheus offered to take him to Film/TheMatrix.
** Well, Spider-Man might have company in the "not completely out of his mind" department in SelfDemonstrating/DoctorDoom, the series' ''other'' main character. Maybe.
* Sara in ''ComicStrip/KnightsOfTheDinnerTable''.
* In ''MortadeloYFilemon'', Filemon is the only main character who occasionally shows a hint of sanity and common sense.
** Ex. The Black Gang has escaped from their shared prison cell. Filemon: "''Ten'' holes in the wall. Only those idiots could have thought of that." Mortadelo and the Superintendant: "What do you mean?"
** It's more like a SanityBall between Mortadelo, Filemon and the Superintendant. The Superintendant usually holds it when he has to explain the mission, Mortadelo and Filemon take turns during it.
* ''{{Nodwick}}'' frequently plays the role of OnlySaneMan to his party, having by far the greatest amount of common sense of the lot and being less bound by the ContractualGenreBlindness that seems to come naturally to adventurers. This happens in almost every standalone story they're in, but by far the most noticeable is the comic's [[http://nodwick.humor.gamespy.com/gamespyarchive/index.php?date=2011-04-24 pastiche of]] ''Literature/LordOfTheRings''.
* It might be a scary thought that the [[LargeHam Caged Demonwolf, Devourer of Worlds]] may be the OnlySaneMan of ''Comicbook/{{Empowered}}''.
** Emp, Mindf**k or Maidman also played the sane man amongst the other capes, depending on the situation. So there we have bondage bait with a track record of always losing, a woman who survived torture from her crazy brother, lives alone on a space station and carried out a telepathic affair with another cape, and [[WholesomeCrossdresser Batman if he'd dressed as a maid.]] The Empverse is wierd...
* Comicbook/GreenLantern seems to be the only person written as remotely sane in ''ComicBook/AllStarBatmanAndRobinTheBoyWonder''.
* ''ILuvHalloween'' - Finch, a skull-mask wearing little kid who stuffs razor blades into apples as revenge for getting an apple for Halloween and sets a woman's head on fire, is actually the most level-headed and rational (next to Devil-lad) of the amoral cast of trick-or-treaters.
* ComicBook/{{Asterix}} and Getafix the Druid are the only two in their town who occasionally show a hint of sanity and common sense.
* Some of the more important members of ComicBook/{{Batman}}'s RoguesGallery are like this in different circumstances.
** SelfDemonstrating/TheJoker is a mass-murdering, antisocial lunatic. However, his deductive reasoning and scientific knowledge are dangerously functional, his ability to predict the outcome of situations is often only foiled by [[ThePowerOfLove abstract principles]], and he even drops hints of understanding that the [[FourthWallObserver universe he lives in is fictional]]. [[DependingOnTheWriter Writer pending, of course.]]
** The Penguin, as one of the few major Batman villains who is typically considered sane (as such his sentencing would be completed at Blackgate Penn rather than Arkham), serves as this by default. When working with other villains he tends to act as a [[CloudcuckoolandersMinder mediator]], defusing arguments and ensuring everyone remains on track; however, he can become exasperated by the "eccentricities" of the other members of Batman's Rogues Gallery, and should he feel that the potential profit of the business arrangement is simply not worth the costs and risks associated with the crime at hand, that his input is being ignored, or that his life and livelihood are being groundlessly threatened by their erratic behavior, there is a strong chance he will [[ScrewThisImOuttaHere wash his hands of the endeavor]] at his earliest convenience. This goes for the [[BatmanTheAnimatedSeries animated series]], as well.
*** If they've ''really'' managed to piss him off in the process he'll sometimes spill his guts to Batman in exchange for immunity.
** Mr. Freeze is a literal case since he is imprisoned in Arkham Asylum in spite of being mentally healthy because it is the only local penal facility that can accommodate his bizarre medical condition of needing a strongly refrigerated environment to live.
* Zibarro from ''ComicBook/AllStarSuperman'' is a very literal OnlySaneMan: He's the only Bizarro on the [[BizarroUniverse planet]] who acts like a normal person, instead of a deranged backwards-speaking manchild.
** If you're not aware, Zibarro was what happened when Bizarro Superman decided everyone on Earth should have a Bizarro-clone; Superman lives on Earth, so he has Bizarro Superman, but Bizarro lives on Earth, so he has Bizarro Bizarro: Zibarro.
* Franklin from the ''{{Peanuts}}'' comics: he is the only character not to have some sort of quirk or obsession. He is also the only person to point out exactly how weird everyone else in Charlie Brown's neighbourhood is. ''And'' - in a twist that was particularly ironic in the late 1960s - he is the only black character in the strip.
-->'''Charlie Brown:''' Franklin! Where are you going?
-->'''Franklin:''' I'm going home, Charlie Brown. This neighborhood has me shook. I didn't mind the girl in the booth or the beagle with the goggles, but that business about the "Great Pumpkin" - no, sir!
-->'''Charlie Brown:''' But...
-->'''Schroeder:''' Hi! Did you guys know there are only sixty more days until Beethoven's birthday?
-->'''Charlie Brown:''' Oh, [[CatchPhrase good grief]]!
-->'''Franklin:''' ''[under his breath]'' Like, wow!
* Wallace Wells, Kim Pine and Stacey Pilgrim are by far the most consistently sane characters in the ''ScottPilgrim'' series.
* In the Giffen-[=DeMatteis=]-Helfer [[JusticeLeagueOfAmerica Justice League]], [[ComicBook/MartianManhunter J'onn J'onnz]] was this for the Justice League of America, while CaptainAtom was for Justice League Europe.
* {{Deadpool}} sometimes has a sidekick named Weasel, a gadgeteer that builds some of his equipment for him. During Deadpool's time with the Great Lakes Avengers this was especially prominent.
* Franchise/{{Batman}}'s trusted BattleButler Alfred often has his moments. Either he'll just snark or suggest [[ForgetsToEat Bruce actually eat something.]]
* This is how [[SonicTheComic Sonic]] feels whenever he's in the [[{{Cloudcuckooland}} Special Zone]] and how he feels while in Shanazar.
* Dr. Caitlin Fairchild, the only one who bothers trying to treat The {{New52}} version of ''Comicbook/{{Superboy}}'' like he's not a thing.
* In ''{{Magazine/Mad}}'', during the parody of FatalAttraction, the dog serves as this, objecting to his owner's immoral and poorly thought out actions.
* ''ComicBook/{{Superlopez}}'': ''All members'' of the Supergroup see themselves as this. No wonder they almost wrecked their secret lair fighting over who would be leader.
* In ''[[ComicBook/TheMultiversity Thunderworld #1]]'', one of the alternate Sivanas is much, ''much'' more restrained than the others, identifying himself as "a man with personal problems," and is greatly disturbed by his insane and violent (and violently insane) counterparts. There's also the fact that he believed the other Sivanas were going to save the world, not enslave it, so he's pretty much the good Sivana counterpart.
* ''Comicbook/AvengersVsXMen'' was an IdiotPlot of ''epic'' proportions. How bad was it? In the main event, Reed Richards was the ''only'' member of the cast to suggest that, since the Phoenix Five have made paradise on earth, maybe the Avengers should just ''let them''.
** In the ''Comicbook/AvengersAcademy'' tie-in, both the Academy kids and X-Teens in general display ''far'' more sense about the situation than the adults. However it's Comicbook/{{X 23}} who's the first to call out Wolverine on his actions and to make it clear that involving the kids in ''any'' way -- including by imprisoning the mutants just for being tied to the X-Men -- is outright ''wrong''. When Phoenix!Emma later returns to destroy Juston's Sentinel, Laura is also the first to tell her off.
* The title character of ''{{NewspaperComics/Dilbert}}''. He's about the least dysfunctional character in the comic and the closest to a genuinely good one.