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- In Hayes's first appearance, she inflicts Body Horror on Kreutzer. Once she reveals herself to Lux, she has a Slasher Smile in the novel and plans to reenact the horrible human experiments that took place on the island 5 years ago.
- Saniya's B-Blood Drag-Ride has ominous Tainted Veins, which causes two of the Triad to question if she's actually using a Drag-Ride. Worse yet, it seems to be responding to Hayes's abyss-taming flute.
- The Old Empire's experiments obviously count, but we don't see the results until Philuffy turns into a humanoid Abyss with Black Eyes of Crazy and proceeds to choke Lux.
- Hayes, everything about her and her ambitions will really have you tossing and turning. And it's revealed that she and her sisters can cheat death via their special Baptism, allowing her to return in Volume 12.
- During episode 12, Hayes launches a Sword Beam that carves into the capital city's diameter, most likely killing many civilians.
- Philuffy's corpse needs a Gory Discretion Shot, not as a result of battle injury, being attacked by wild beasts, or being set upon by brigands, but in an official Empire laboratory where she's dragged against her will, no older than 12-years-old, as a result of officially sanctioned Empire experimentation, and she's infected with a piece of an Eldritch Abomination (Ragnarok Yggdrasil), and being well aware of it. What's worse is that she can be controlled by a special flute, and attempting to resist this control could slowly and painfully kill her. Small wonder she runs and hides, begging Lux to kill her when he finds her. The only good news is that the process might be reversible depending on what technology the alliance finds at Avalon.
- The effects of Elixir aren't pretty, since overdosing on it gives the user Tainted Veins, Black Eyes of Crazy, and a good dose of Sanity Slippage, turning them into Humanoid Abomination known as "Nocturne." Worse yet, upon death, the user will turn into dust like an Abyss. The only good news is that if the user doesn't overdose on it or doesn't expend themselves too much, the effects aren't permanent as shown in Mel's case. Additionally, the effects of Elixir are permanent, albeit without the risk of turning into a monster if the user undergoes proper "Baptism" surgery.
- In Volume 12, the main cast has to risk-taking small doses of Elixir in order to resist Iblis's ability to drive them mad. While the dosage is small enough to avoid the side-effects, it's still unsettling that the risk is still there.
- Volume 14 Chapter 4 reveals the purpose of the Abyss is to kill people and harvest them as ingredients to make Elixir. The effects of Elixir is more potent the more genetically similar the sacrifice is to the user, which implies the Lords only kept the "traitor" branch around as high-quality livestock.
- The Ragnarok Iblis has the ability to give people in a large radius horrifying delusions. When the Triad is affected, they imagine an Abyss eating a student and chopping off her head, while another Abyss possesses another student. Worse yet, if they weren't snapped out of it, they could have been tricked into attacking their classmates.
- Listelka may be outwardly polite, but she can be just as nightmarish as Hayes.
- She becomes uncharacteristically cold if Fugil is insulted, to the point where Hayes is frightened. Mishis won't even voice her suspicions about him in fear of incurring Listelka's wrath.
- Not only was she willing to set Lux's Wedge to kill Aeril, but she also planned on turning her into a vegetable and sex doll to propagate the Lords' genes. She says all this to her maid with absolutely no hesitation or guilt, showing that she's nearly as sociopathic, but higher-functioning, than Hayes.
- After Aeril activates a portion of Avalon, Listelka uses the Ruin's functions to revive the Ragnaroks and massacre most of the world alliance's army, giving her a larger body count than Hayes.
- The most unexpected example is Queen Raffi, who spent most of the story as a Reasonable Authority Figure trying to hold the kingdom together despite all the rebel elements trying to restore the Old Empire. After teaming up with Fugil and accepting Elixir, she becomes a lot more ruthless, but in an eerily calm and composed manner, to the point where some readers compare her to Listelka.
- She personally guts a member of the Old Empire faction with a sword device before leaving the rest to be slaughtered by the Automata. Even if they deserved it due to all the tragedy they put her through, she's still disturbingly nonchalant about it.
- When removing Lux's collar, she directs killing intent towards him and is in a position to throttle him to death. While she didn't follow through with it, she could have ended the story right there. Though this also counts as a Awesome Moment for Lux for managing to keep a poker face during this tense moment, causing Raffi to falsely assume that Lux is unaware of her plans.
- In Volume 17, she tortures Alma with Iblis's insanity-inducing sound. It shows how far she has fallen now that she's willing to torture her own kin.
- She starts eating people because of Sacred Eclipse's impulse to eat humans and convert them into Elixir. At one point, a Drake user from the Azure Division tries to spy on her, hoping that he won't be noticed. She calmly states, with blood on her mouth, that she is fully aware of his presence, and then Mind Rapes him with Iblis's power before eating him. Fortunately, she didn't notice Yoruka also spying on her.
- Her behavior is due to being fused with Sacred Eclipse, and Fugil had other originally well-intentioned people do the same thing. Worse yet, anyone who fuses with Sacred Eclipse is eventually destroyed in mind and body. Then there's the implication that Fugil was originally planning for this to happen to Lux.
